JP2024508808A5 - - Google Patents

Info

Publication number
JP2024508808A5
JP2024508808A5 JP2023551180A JP2023551180A JP2024508808A5 JP 2024508808 A5 JP2024508808 A5 JP 2024508808A5 JP 2023551180 A JP2023551180 A JP 2023551180A JP 2023551180 A JP2023551180 A JP 2023551180A JP 2024508808 A5 JP2024508808 A5 JP 2024508808A5
Authority
JP
Japan
Prior art keywords
seq
car
cancer
sequence
cell
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023551180A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024508808A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2022/018117 external-priority patent/WO2022183101A1/en
Publication of JP2024508808A publication Critical patent/JP2024508808A/ja
Publication of JP2024508808A5 publication Critical patent/JP2024508808A5/ja
Pending legal-status Critical Current

Links

JP2023551180A 2021-02-26 2022-02-28 抗muc1-c抗体及びcar-t構造 Pending JP2024508808A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163154618P 2021-02-26 2021-02-26
US63/154,618 2021-02-26
PCT/US2022/018117 WO2022183101A1 (en) 2021-02-26 2022-02-28 Anti-muc1-c antibodies and car-t structures

Publications (2)

Publication Number Publication Date
JP2024508808A JP2024508808A (ja) 2024-02-28
JP2024508808A5 true JP2024508808A5 (enExample) 2025-03-07

Family

ID=80780549

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023551180A Pending JP2024508808A (ja) 2021-02-26 2022-02-28 抗muc1-c抗体及びcar-t構造

Country Status (9)

Country Link
US (1) US20240182597A1 (enExample)
EP (1) EP4298129A1 (enExample)
JP (1) JP2024508808A (enExample)
KR (1) KR20230150825A (enExample)
CN (1) CN116917327A (enExample)
AU (1) AU2022226565A1 (enExample)
CA (1) CA3211142A1 (enExample)
MX (1) MX2023009882A (enExample)
WO (1) WO2022183101A1 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL322083A (en) 2016-08-24 2025-09-01 Teneobio Inc Non-human transgenic animals that produce modified heavy chain antibodies only
IL317134A (en) 2016-12-21 2025-01-01 Teneobio Inc An antibody containing only heavy chains that binds a human B-cell maturation antigen, a pharmaceutical composition containing the same, its use in the treatment of B-cell disorders and a method for its preparation
CN111683966B (zh) 2017-12-22 2023-07-11 特尼奥生物股份有限公司 与cd22结合的重链抗体
WO2020206330A1 (en) 2019-04-05 2020-10-08 Teneobio, Inc. Heavy chain antibodies binding to psma
CR20210622A (es) 2019-06-14 2022-06-27 Teneobio Inc Anticuerpos multiespecíficos de cadena pesada que se unen a cd22 y cd3
WO2025218621A1 (zh) * 2024-04-15 2025-10-23 原启生物科技(上海)有限责任公司 靶向muc1的抗原结合蛋白

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
IL85035A0 (en) 1987-01-08 1988-06-30 Int Genetic Eng Polynucleotide molecule,a chimeric antibody with specificity for human b cell surface antigen,a process for the preparation and methods utilizing the same
EP1400536A1 (en) 1991-06-14 2004-03-24 Genentech Inc. Method for making humanized antibodies
US6096871A (en) 1995-04-14 2000-08-01 Genentech, Inc. Polypeptides altered to contain an epitope from the Fc region of an IgG molecule for increased half-life
JP4046354B2 (ja) 1996-03-18 2008-02-13 ボード オブ リージェンツ,ザ ユニバーシティ オブ テキサス システム 増大した半減期を有する免疫グロブリン様ドメイン
GB0115256D0 (en) 2001-06-21 2001-08-15 Babraham Inst Mouse light chain locus
WO2004042017A2 (en) 2002-10-31 2004-05-21 Genentech, Inc. Methods and compositions for increasing antibody production
EP1585768A2 (en) 2003-01-23 2005-10-19 Genentech, Inc. Methods for producing humanized antibodies and improving yield of antibodies or antigen binding fragments in cell culture
KR101151957B1 (ko) 2004-07-22 2012-06-01 로저 킹돈 크레이그 결합 분자
US20160355591A1 (en) 2011-05-02 2016-12-08 Immunomedics, Inc. Subcutaneous anti-hla-dr monoclonal antibody for treatment of hematologic malignancies
US20100122358A1 (en) 2008-06-06 2010-05-13 Crescendo Biologics Limited H-Chain-only antibodies
MX341884B (es) 2009-03-10 2016-09-07 Biogen Ma Inc Anticuerpos anti-antigeno de maduracion de celulas b (bcma).
GB0905023D0 (en) 2009-03-24 2009-05-06 Univ Erasmus Medical Ct Binding molecules
US9345661B2 (en) 2009-07-31 2016-05-24 Genentech, Inc. Subcutaneous anti-HER2 antibody formulations and uses thereof
WO2015116753A1 (en) * 2014-01-29 2015-08-06 Dana-Farber Cancer Institute, Inc. Antibodies against the muc1-c/extracellular domain (muc1-c/ecd)
KR20250175345A (ko) 2016-06-21 2025-12-16 테네오바이오, 인코포레이티드 Cd3 결합 항체
WO2018014039A1 (en) * 2016-07-15 2018-01-18 Poseida Therapeutics, Inc. Chimeric antigen receptors (cars) specific for muc1 and methods for their use
IL322083A (en) 2016-08-24 2025-09-01 Teneobio Inc Non-human transgenic animals that produce modified heavy chain antibodies only
PE20241349A1 (es) 2016-09-14 2024-07-03 Teneobio Inc Anticuerpos de union a cd3
AU2020407235A1 (en) * 2019-12-20 2022-07-07 Poseida Therapeutics, Inc. Anti-MUC1 compositions and methods of use

Similar Documents

Publication Publication Date Title
JP2024508808A5 (enExample)
JP7562528B2 (ja) 抗体及びその用途
JP7685095B2 (ja) 多重特異性抗体とその作製及び使用方法
TWI821474B (zh) Cd3抗體及其藥物用途
CN103687879B (zh) 多价抗原结合fv分子
JP2024507540A5 (enExample)
JP7399852B2 (ja) 多重特異性抗体とその作製及び使用方法
JP2018502050A5 (enExample)
JP2021530236A5 (enExample)
CN113330034A (zh) 针对B7-H3的IgV结构域的单克隆抗体及其用途
JP2022505445A5 (enExample)
JP2022550243A (ja) 抗pd-1抗体及びその使用
JP2020502233A5 (enExample)
KR20210107747A (ko) 항체 융합 단백질, 이의 제조 방법 및 이의 적용
JP2026510999A (ja) Cd19/cd38多重特異性抗体
WO2022194201A1 (zh) 一种靶向cldn18.2的抗体或其抗原结合片段及其应用
KR20250028265A (ko) 항체 및 이의 용도
KR20250012612A (ko) 고형 종양을 치료하는 방법
CN116496398B (zh) 一种特异性结合CD44的v5外显子的抗体及其用途
TWI922434B (zh) 一種融合蛋白及其用途
WO2025167974A1 (zh) 多特异性抗体或抗原结合片段
HK40111322A (zh) 多特异性抗体及其制备和使用方法
HK40111323A (zh) 多特异性抗体及其制备和使用方法
TW202400232A (zh) 多特異性分子與免疫檢查點抑制劑之組合
KR20250021381A (ko) 인테그린 베타-2를 표적화하는 항체