JP2024518710A5 - - Google Patents

Info

Publication number
JP2024518710A5
JP2024518710A5 JP2023562483A JP2023562483A JP2024518710A5 JP 2024518710 A5 JP2024518710 A5 JP 2024518710A5 JP 2023562483 A JP2023562483 A JP 2023562483A JP 2023562483 A JP2023562483 A JP 2023562483A JP 2024518710 A5 JP2024518710 A5 JP 2024518710A5
Authority
JP
Japan
Prior art keywords
formula
ionizable lipid
polymerosome
ionizable
seq
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023562483A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024518710A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/EP2022/059701 external-priority patent/WO2022218957A1/en
Publication of JP2024518710A publication Critical patent/JP2024518710A/ja
Publication of JP2024518710A5 publication Critical patent/JP2024518710A5/ja
Pending legal-status Critical Current

Links

JP2023562483A 2021-04-12 2022-04-12 可溶性封入ポリヌクレオチドとイオン化可能脂質とを含むポリマーソームならびにその作製および使用方法 Pending JP2024518710A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP21167911 2021-04-12
EP21167911.3 2021-04-12
PCT/EP2022/059701 WO2022218957A1 (en) 2021-04-12 2022-04-12 Polymersomes comprising a soluble encapsulated polynucleotide and an ionizable lipid as well as methods of making and uses thereof

Publications (2)

Publication Number Publication Date
JP2024518710A JP2024518710A (ja) 2024-05-02
JP2024518710A5 true JP2024518710A5 (https=) 2025-04-21

Family

ID=75786882

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023562483A Pending JP2024518710A (ja) 2021-04-12 2022-04-12 可溶性封入ポリヌクレオチドとイオン化可能脂質とを含むポリマーソームならびにその作製および使用方法

Country Status (8)

Country Link
US (1) US20250281405A1 (https=)
EP (1) EP4322922A1 (https=)
JP (1) JP2024518710A (https=)
CN (1) CN117440798A (https=)
AU (1) AU2022258552A1 (https=)
BR (1) BR112023021224A2 (https=)
CA (1) CA3214934A1 (https=)
WO (1) WO2022218957A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW202543585A (zh) 2024-03-08 2025-11-16 美商健臻公司 脂質奈米粒子
WO2026030375A2 (en) 2024-07-30 2026-02-05 Genzyme Corporation Lipid nanoparticles and methods of manufacture and use thereof

Family Cites Families (52)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US980A (en) 1838-10-13 Improvement in the mode of hardening or chilling the hubs of car and other wheels
US70185A (en) 1867-10-29 fan oh be
US569825A (en) 1896-10-20 John h
US5591A (en) 1848-05-23 Pump fob
US5661A (en) 1848-07-11 Boring and mortising machine
US669A (en) 1838-04-02 In the manufacture of gunpowder
US16A (en) 1836-08-31 Edwin m
US4676A (en) 1846-07-31 roller
US567A (en) 1838-01-09 Machine for r-uibbii
US5545A (en) 1848-05-02 Improvement in machinery for separating gold
US807A (en) 1838-06-27 Samuel gilson
US5625A (en) 1848-06-13 Machinery for cutting and punching copper sheathing
US2003A (en) 1841-03-12 Improvement in horizontal windivhlls
US4816A (en) 1846-10-17 Bell machinery for hotels
US633425A (en) 1899-01-26 1899-09-19 Louis Henry Clyborne Wire-tightener.
GB8308235D0 (en) 1983-03-25 1983-05-05 Celltech Ltd Polypeptides
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
JPS6147500A (ja) 1984-08-15 1986-03-07 Res Dev Corp Of Japan キメラモノクロ−ナル抗体及びその製造法
EP0173494A3 (en) 1984-08-27 1987-11-25 The Board Of Trustees Of The Leland Stanford Junior University Chimeric receptors by dna splicing and expression
GB8422238D0 (en) 1984-09-03 1984-10-10 Neuberger M S Chimeric proteins
US4676980A (en) 1985-09-23 1987-06-30 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Target specific cross-linked heteroantibodies
GB8607679D0 (en) 1986-03-27 1986-04-30 Winter G P Recombinant dna product
US5225539A (en) 1986-03-27 1993-07-06 Medical Research Council Recombinant altered antibodies and methods of making altered antibodies
US5567610A (en) 1986-09-04 1996-10-22 Bioinvent International Ab Method of producing human monoclonal antibodies and kit therefor
JP3101690B2 (ja) 1987-03-18 2000-10-23 エス・ビィ・２・インコーポレイテッド 変性抗体の、または変性抗体に関する改良
US5530101A (en) 1988-12-28 1996-06-25 Protein Design Labs, Inc. Humanized immunoglobulins
US5859205A (en) 1989-12-21 1999-01-12 Celltech Limited Humanised antibodies
WO1996033735A1 (en) 1995-04-27 1996-10-31 Abgenix, Inc. Human antibodies derived from immunized xenomice
US5229275A (en) 1990-04-26 1993-07-20 Akzo N.V. In-vitro method for producing antigen-specific human monoclonal antibodies
GB9021679D0 (en) 1990-10-05 1990-11-21 Gorman Scott David Antibody preparation
EP1400536A1 (en) 1991-06-14 2004-03-24 Genentech Inc. Method for making humanized antibodies
MX9204374A (es) 1991-07-25 1993-03-01 Idec Pharma Corp Anticuerpo recombinante y metodo para su produccion.
US5565332A (en) 1991-09-23 1996-10-15 Medical Research Council Production of chimeric antibodies - a combinatorial approach
WO1993008829A1 (en) 1991-11-04 1993-05-13 The Regents Of The University Of California Compositions that mediate killing of hiv-infected cells
US5573905A (en) 1992-03-30 1996-11-12 The Scripps Research Institute Encoded combinatorial chemical libraries
CA2140280A1 (en) 1992-08-17 1994-03-03 Avi J. Ashkenazi Bispecific immunoadhesins
US5731168A (en) 1995-03-01 1998-03-24 Genentech, Inc. Method for making heteromultimeric polypeptides
WO1996034096A1 (en) 1995-04-28 1996-10-31 Abgenix, Inc. Human antibodies derived from immunized xenomice
ES2176484T3 (es) 1995-08-18 2002-12-01 Morphosys Ag Bancos de proteinas/(poli)peptidos.
DE19544393A1 (de) 1995-11-15 1997-05-22 Hoechst Schering Agrevo Gmbh Synergistische herbizide Mischungen
EP0983303B1 (en) 1997-05-21 2006-03-08 Biovation Limited Method for the production of non-immunogenic proteins
AU776910B2 (en) 1998-12-08 2004-09-23 Merck Patent Gesellschaft Mit Beschrankter Haftung Modifying protein immunogenicity
US8323696B2 (en) 2008-08-29 2012-12-04 Ecole Polytechnique Federale De Lausanne Nanoparticles for immunotherapy
CN102460150B (zh) 2009-04-20 2015-05-20 新加坡科技研究局 囊泡系统及其用途
EP2601262A4 (en) 2010-08-05 2014-01-22 Agency Science Tech & Res VESIGN STRUCTURE WITH SEVERAL CHAMBERS AND METHOD FOR THEIR EDUCATION
EP4218808A3 (en) 2012-03-12 2023-08-09 Advanced BioAdjuvants, LLC Adjuvant and vaccine compositions
CN104936579B (zh) 2012-11-19 2020-02-07 新加坡科技研究局 用于引发对免疫原的免疫响应的方法
EP2898894A1 (en) 2014-01-27 2015-07-29 LTS LOHMANN Therapie-Systeme AG Nano-in-micro particles for intradermal delivery
US9636397B2 (en) 2015-03-24 2017-05-02 VaxLiant, LLC Adjuvant compositions and related methods
EP3162361A1 (en) * 2015-11-02 2017-05-03 Universität für Bodenkultur Wien Improved magnetically reactive vesicular bodies
WO2019145475A2 (en) * 2018-01-25 2019-08-01 Acm Biolabs Pte Ltd Polymersomes comprising a soluble encapsulated antigen as well as methods of making and uses thereof
KR20210061393A (ko) * 2018-09-18 2021-05-27 유니버시테이트 젠트 치료용 나노입자 및 이의 사용 방법

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