|
US4361549A
(en)
|
1979-04-26 |
1982-11-30 |
Ortho Pharmaceutical Corporation |
Complement-fixing monoclonal antibody to human T cells, and methods of preparing same
|
|
EP0198015B2
(en)
|
1984-10-02 |
1995-07-19 |
Biogen, Inc. |
Production of streptavidin-like polypeptides
|
|
US4690915A
(en)
|
1985-08-08 |
1987-09-01 |
The United States Of America As Represented By The Department Of Health And Human Services |
Adoptive immunotherapy as a treatment modality in humans
|
|
IN165717B
(enExample)
|
1986-08-07 |
1989-12-23 |
Battelle Memorial Institute |
|
|
US4851341A
(en)
|
1986-12-19 |
1989-07-25 |
Immunex Corporation |
Immunoaffinity purification system
|
|
US5219740A
(en)
|
1987-02-13 |
1993-06-15 |
Fred Hutchinson Cancer Research Center |
Retroviral gene transfer into diploid fibroblasts for gene therapy
|
|
US6303121B1
(en)
|
1992-07-30 |
2001-10-16 |
Advanced Research And Technology |
Method of using human receptor protein 4-1BB
|
|
US6352694B1
(en)
|
1994-06-03 |
2002-03-05 |
Genetics Institute, Inc. |
Methods for inducing a population of T cells to proliferate using agents which recognize TCR/CD3 and ligands which stimulate an accessory molecule on the surface of the T cells
|
|
IE913929A1
(en)
|
1990-11-13 |
1992-05-20 |
Immunex Corp |
Bifunctional selectable fusion genes
|
|
DE4228458A1
(de)
|
1992-08-27 |
1994-06-01 |
Beiersdorf Ag |
Multicistronische Expressionseinheiten und deren Verwendung
|
|
DE4237113B4
(de)
|
1992-11-03 |
2006-10-12 |
"Iba Gmbh" |
Peptide und deren Fusionsproteine, Expressionsvektor und Verfahren zur Herstellung eines Fusionsproteins
|
|
AU6953394A
(en)
|
1993-05-21 |
1994-12-20 |
Targeted Genetics Corporation |
Bifunctional selectable fusion genes based on the cytosine deaminase (cd) gene
|
|
ATE293686T1
(de)
|
1993-06-04 |
2005-05-15 |
Us Navy |
Verfahren zur selektiven stimulierung der t- zellproliferation.
|
|
US5827642A
(en)
|
1994-08-31 |
1998-10-27 |
Fred Hutchinson Cancer Research Center |
Rapid expansion method ("REM") for in vitro propagation of T lymphocytes
|
|
WO1996013593A2
(en)
|
1994-10-26 |
1996-05-09 |
Procept, Inc. |
Soluble single chain t cell receptors
|
|
WO1996018105A1
(en)
|
1994-12-06 |
1996-06-13 |
The President And Fellows Of Harvard College |
Single chain t-cell receptor
|
|
AU5132096A
(en)
|
1995-01-30 |
1996-08-21 |
Terrapin Technologies, Inc. |
Glubodies - multiplicities of proteins capable of binding a variety of small molecules
|
|
AU708375B2
(en)
|
1995-02-09 |
1999-08-05 |
University Of Washington |
Modified-affinity streptavidin
|
|
US6022951A
(en)
|
1995-04-11 |
2000-02-08 |
Univ Boston |
Streptavidin mutants
|
|
DE19608753C1
(de)
|
1996-03-06 |
1997-06-26 |
Medigene Gmbh |
Transduktionssystem und seine Verwendung
|
|
WO1997034634A1
(en)
|
1996-03-20 |
1997-09-25 |
Sloan-Kettering Institute For Cancer Research |
Single chain fv constructs of anti-ganglioside gd2 antibodies
|
|
DE19641876B4
(de)
|
1996-10-10 |
2011-09-29 |
Iba Gmbh |
Streptavidinmuteine
|
|
EP0977770A4
(en)
|
1997-03-14 |
2000-04-05 |
Univ Boston |
DIFFERENTLY FLAVORED STREPTAVIDINE
|
|
ATE533784T1
(de)
|
1997-10-02 |
2011-12-15 |
Altor Bioscience Corp |
Lösliche, einzelkettige proteine des t- zellrezeptors
|
|
US5985658A
(en)
|
1997-11-14 |
1999-11-16 |
Health Research Incorporated |
Calmodulin-based cell separation technique
|
|
WO1999060120A2
(en)
|
1998-05-19 |
1999-11-25 |
Avidex Limited |
Soluble t cell receptor
|
|
ATE304375T1
(de)
|
1998-05-23 |
2005-09-15 |
Univ Leiden Medical Ct |
Cd40 bindende antikörper und ctl peptide zur behandlung von tumoren
|
|
EP1109921A4
(en)
|
1998-09-04 |
2002-08-28 |
Sloan Kettering Inst Cancer |
FUSION RECEPTORS SPECIFIC TO MEMBRANE SPECIFIC PROSTATIC ANTIGEN AND USES THEREOF
|
|
US6410319B1
(en)
|
1998-10-20 |
2002-06-25 |
City Of Hope |
CD20-specific redirected T cells and their use in cellular immunotherapy of CD20+ malignancies
|
|
DE19932688B4
(de)
|
1999-07-13 |
2009-10-08 |
Scil Proteins Gmbh |
Design von Beta-Faltblatt-Proteinen des gamma-II-kristallins antikörperähnlichen
|
|
WO2001056603A1
(en)
|
2000-02-01 |
2001-08-09 |
Tanox, Inc. |
Cd40-binding apc-activating molecules
|
|
US20020131960A1
(en)
|
2000-06-02 |
2002-09-19 |
Michel Sadelain |
Artificial antigen presenting cells and methods of use thereof
|
|
ATE338124T1
(de)
|
2000-11-07 |
2006-09-15 |
Hope City |
Cd19-spezifische umgezielte immunzellen
|
|
EP1227321A1
(en)
|
2000-12-28 |
2002-07-31 |
Institut für Bioanalytik GmbH |
Reversible MHC multimer staining for functional purification of antigen-specific T cells
|
|
DE10113776B4
(de)
|
2001-03-21 |
2012-08-09 |
"Iba Gmbh" |
Isoliertes streptavidinbindendes, kompetitiv eluierbares Peptid, dieses umfassendes Fusionspeptid, dafür codierende Nukleinsäure, Expressionsvektor, Verfahren zur Herstellung eines rekombinanten Fusionsproteins und Verfahren zum Nachweis und/oder zur Gewinnung des Fusionsproteins
|
|
US7070995B2
(en)
|
2001-04-11 |
2006-07-04 |
City Of Hope |
CE7-specific redirected immune cells
|
|
US20090257994A1
(en)
|
2001-04-30 |
2009-10-15 |
City Of Hope |
Chimeric immunoreceptor useful in treating human cancers
|
|
IL160359A0
(en)
|
2001-08-31 |
2004-07-25 |
Avidex Ltd |
Soluble t cell receptor
|
|
WO2003029462A1
(en)
|
2001-09-27 |
2003-04-10 |
Pieris Proteolab Ag |
Muteins of human neutrophil gelatinase-associated lipocalin and related proteins
|
|
US7939059B2
(en)
|
2001-12-10 |
2011-05-10 |
California Institute Of Technology |
Method for the generation of antigen-specific lymphocytes
|
|
US20030170238A1
(en)
|
2002-03-07 |
2003-09-11 |
Gruenberg Micheal L. |
Re-activated T-cells for adoptive immunotherapy
|
|
US7446190B2
(en)
|
2002-05-28 |
2008-11-04 |
Sloan-Kettering Institute For Cancer Research |
Nucleic acids encoding chimeric T cell receptors
|
|
FR2841905B1
(fr)
|
2002-07-05 |
2004-09-03 |
Centre Nat Rech Scient |
Fragments fab mutants de l'anticorps anti-cd4 chimere 13b8.2 et leurs applications
|
|
CA2501870C
(en)
|
2002-10-09 |
2013-07-02 |
Avidex Limited |
Single chain recombinant t cell receptors
|
|
US20050129671A1
(en)
|
2003-03-11 |
2005-06-16 |
City Of Hope |
Mammalian antigen-presenting T cells and bi-specific T cells
|
|
US20050025763A1
(en)
|
2003-05-08 |
2005-02-03 |
Protein Design Laboratories, Inc. |
Therapeutic use of anti-CS1 antibodies
|
|
AU2005235811B2
(en)
|
2004-02-06 |
2011-11-03 |
Morphosys Ag |
Anti-CD38 human antibodies and uses therefor
|
|
ATE475669T1
(de)
|
2004-06-29 |
2010-08-15 |
Immunocore Ltd |
Einen modifizierten t-zellen-rezeptor exprimierende zellen
|
|
WO2006054961A2
(en)
|
2004-11-12 |
2006-05-26 |
Genentech, Inc. |
Novel composition and methods for the treatment of immune related diseases
|
|
US8188232B1
(en)
|
2004-11-15 |
2012-05-29 |
Washington University In St. Louis |
Compositions and methods for modulating lymphocyte activity
|
|
JP5225069B2
(ja)
|
2005-03-23 |
2013-07-03 |
ゲンマブ エー／エス |
多発性骨髄腫の治療のためのｃｄ３８に対する抗体
|
|
EP1914242A1
(en)
|
2006-10-19 |
2008-04-23 |
Sanofi-Aventis |
Novel anti-CD38 antibodies for the treatment of cancer
|
|
GB0620894D0
(en)
|
2006-10-20 |
2006-11-29 |
Univ Southampton |
Human immune therapies using a CD27 agonist alone or in combination with other immune modulators
|
|
SI2856876T1
(en)
|
2007-03-30 |
2018-04-30 |
Memorial Sloan-Kettering Cancer Center |
Constitutive expression of costimulatory ligands on adoptively transferred T lymphocytes
|
|
AU2008247382B2
(en)
|
2007-05-07 |
2014-06-05 |
Medimmune, Llc |
Anti-ICOS antibodies and their use in treatment of oncology, transplantation and autoimmune disease
|
|
US8479118B2
(en)
|
2007-12-10 |
2013-07-02 |
Microsoft Corporation |
Switching search providers within a browser search box
|
|
US9221914B2
(en)
|
2007-12-26 |
2015-12-29 |
Biotest Ag |
Agents targeting CD138 and uses thereof
|
|
JP5173594B2
(ja)
|
2008-05-27 |
2013-04-03 |
キヤノン株式会社 |
管理装置、画像形成装置及びそれらの処理方法
|
|
EP2331566B1
(en)
|
2008-08-26 |
2015-10-07 |
City of Hope |
Method and compositions for enhanced anti-tumor effector functioning of t cells
|
|
EP2361263A1
(en)
|
2008-10-31 |
2011-08-31 |
Abbott Biotherapeutics Corp. |
Use of anti-cs1 antibodies for treatment of rare lymphomas
|
|
MX341884B
(es)
|
2009-03-10 |
2016-09-07 |
Biogen Ma Inc |
Anticuerpos anti-antigeno de maduracion de celulas b (bcma).
|
|
RU2587621C2
(ru)
|
2009-04-01 |
2016-06-20 |
Дженентек, Инк. |
АНТИТЕЛА К FcRH5, ИХ ИММУНОКОНЪЮГАТЫ И СПОСОБЫ ИХ ПРИМЕНЕНИЯ
|
|
EP2486049A1
(en)
|
2009-10-06 |
2012-08-15 |
The Board Of Trustees Of The UniversityOf Illinois |
Human single-chain t cell receptors
|
|
TR201904484T4
(tr)
|
2009-11-03 |
2019-05-21 |
Hope City |
Transdüse T hücre seçimine yönelik kesik epiderimal büyüme faktörü reseptörü (EGFRt).
|
|
PH12013501201A1
(en)
|
2010-12-09 |
2013-07-29 |
Univ Pennsylvania |
Use of chimeric antigen receptor-modified t cells to treat cancer
|
|
JOP20210044A1
(ar)
|
2010-12-30 |
2017-06-16 |
Takeda Pharmaceuticals Co |
الأجسام المضادة لـ cd38
|
|
US9987308B2
(en)
|
2011-03-23 |
2018-06-05 |
Fred Hutchinson Cancer Research Center |
Method and compositions for cellular immunotherapy
|
|
US8398282B2
(en)
|
2011-05-12 |
2013-03-19 |
Delphi Technologies, Inc. |
Vehicle front lighting assembly and systems having a variable tint electrowetting element
|
|
US9023604B2
(en)
|
2011-07-18 |
2015-05-05 |
Iba Gmbh |
Method of reversibly staining a target cell
|
|
GB201116092D0
(en)
|
2011-09-16 |
2011-11-02 |
Bioceros B V |
Antibodies and uses thereof
|
|
CN104080797A
(zh)
|
2011-11-11 |
2014-10-01 |
弗雷德哈钦森癌症研究中心 |
针对癌症的靶向细胞周期蛋白a1的t细胞免疫疗法
|
|
CA2861491C
(en)
|
2012-02-13 |
2020-08-25 |
Seattle Children's Hospital D/B/A Seattle Children's Research Institute |
Bispecific chimeric antigen receptors and therapeutic uses thereof
|
|
WO2013126726A1
(en)
|
2012-02-22 |
2013-08-29 |
The Trustees Of The University Of Pennsylvania |
Double transgenic t cells comprising a car and a tcr and their methods of use
|
|
ES3011307T3
(en)
|
2012-02-23 |
2025-04-07 |
Juno Therapeutics Gmbh |
Chromatographic isolation of cells and other complex biological materials
|
|
RU2766608C2
(ru)
|
2012-04-11 |
2022-03-15 |
Дзе Юнайтед Стейтс Оф Америка, Эз Репрезентед Бай Дзе Секретари, Департмент Оф Хелс Энд Хьюман Сёрвисез |
Химерные антигенные рецепторы, нацеленные на антиген созревания b-клеток
|
|
EP2844743B1
(en)
|
2012-05-03 |
2021-01-13 |
Fred Hutchinson Cancer Research Center |
Enhanced affinity t cell receptors and methods for making the same
|
|
BR122020002986A8
(pt)
|
2012-08-20 |
2023-04-18 |
Seattle Childrens Hospital Dba Seattle Childrens Res Inst |
Método e composições para imunoterapia celular
|
|
MX370148B
(es)
|
2012-10-02 |
2019-12-03 |
Memorial Sloan Kettering Cancer Center |
Composiciones y su uso para inmunoterapia.
|
|
CN105073770B
(zh)
|
2012-11-16 |
2019-08-06 |
Iba股份有限公司 |
链霉亲和素突变蛋白及其使用方法
|
|
UY35468A
(es)
|
2013-03-16 |
2014-10-31 |
Novartis Ag |
Tratamiento de cáncer utilizando un receptor quimérico de antígeno anti-cd19
|
|
TWI725931B
(zh)
|
2013-06-24 |
2021-05-01 |
美商建南德克公司 |
抗ｆｃｒｈ５抗體
|
|
EP3131927B8
(en)
|
2014-04-14 |
2020-12-23 |
Cellectis |
Bcma (cd269) specific chimeric antigen receptors for cancer immunotherapy
|
|
SI3132247T1
(sl)
|
2014-04-16 |
2021-12-31 |
Juno Therapeutics Gmbh |
Postopki, kompleti in naprava za povečanje populacije celic
|
|
CA2946312A1
(en)
|
2014-04-23 |
2015-10-29 |
Juno Therapeutics, Inc. |
Methods for isolating, culturing, and genetically engineering immune cell populations for adoptive therapy
|
|
CN113604491A
(zh)
|
2014-05-02 |
2021-11-05 |
宾夕法尼亚大学董事会 |
嵌合自身抗体受体t细胞的组合物和方法
|
|
BR112017001183A2
(pt)
|
2014-07-21 |
2017-11-28 |
Novartis Ag |
tratamento de câncer usando receptor de antígeno quimérico anti-bcma humanizado
|
|
ES2878449T3
(es)
|
2014-07-24 |
2021-11-18 |
2Seventy Bio Inc |
Receptores antigénicos quiméricos de BCMA
|
|
TWI751102B
(zh)
|
2014-08-28 |
2022-01-01 |
美商奇諾治療有限公司 |
對ｃｄ１９具專一性之抗體及嵌合抗原受體
|
|
PL3198345T3
(pl)
|
2014-09-22 |
2021-08-23 |
Sacmi Cooperativa Meccanici Imola Societa' Cooperativa |
Linia do produkcji pojedynczych wyrobów w następujących po sobie w cyklu ciągłym
|
|
ES2987570T3
(es)
|
2014-11-05 |
2024-11-15 |
Juno Therapeutics Inc |
Métodos para la transducción y el procesamiento de células
|
|
AU2015357543B2
(en)
|
2014-12-05 |
2021-10-21 |
Eureka Therapeutics, Inc. |
Chimeric antigen receptors targeting Fc Receptor-like 5 and uses thereof
|
|
CN118271463A
(zh)
|
2014-12-05 |
2024-07-02 |
纪念斯隆-凯特琳癌症中心 |
靶向g-蛋白偶联受体的嵌合抗原受体及其用途
|
|
MY191537A
(en)
|
2014-12-05 |
2022-06-30 |
Memorial Sloan Kettering Cancer Center |
Chimeric antigen receptors targeting b-cell maturation antigen and uses thereof
|
|
SI3226897T1
(sl)
|
2014-12-05 |
2021-08-31 |
Memorial Sloan Kettering Cancer Center |
Protitelesa, ki ciljajo na B-celični maturacijski antigen, in postopki uporabe
|
|
BR112017011932A8
(pt)
|
2014-12-05 |
2022-11-08 |
Memorial Sloan Kettering Cancer Center |
Anticorpos direcionados a receptor acoplado a proteína g e métodos de uso
|
|
HRP20191873T1
(hr)
|
2014-12-12 |
2020-01-24 |
Bluebird Bio, Inc. |
Kimerni antigenski receptori
|
|
ES2818103T3
(es)
|
2015-01-16 |
2021-04-09 |
Juno Therapeutics Inc |
Anticuerpos y receptores de antígenos quiméricos específicos para ROR1
|
|
CN105384825B
(zh)
|
2015-08-11 |
2018-06-01 |
南京传奇生物科技有限公司 |
一种基于单域抗体的双特异性嵌合抗原受体及其应用
|
|
AU2016341529B2
(en)
|
2015-10-22 |
2023-03-30 |
Juno Therapeutics Gmbh |
Methods for culturing cells and kits and apparatus for same
|
|
EP3365453A2
(en)
*
|
2015-10-22 |
2018-08-29 |
Juno Therapeutics GmbH |
Methods, kits, agents and apparatuses for transduction
|
|
BR112018011336A2
(pt)
|
2015-12-04 |
2018-12-04 |
Memorial Sloan-Kettering Cancer Center |
anticorpo anti-fcrl5 isolado ou um fragmento de ligação ao antígeno do mesmo, anticorpo scfv anti-fcrl5 isolado, anticorpo isolado ou porção de ligação ao antígeno do mesmo, composição, imunoconjugado, molécula biespecífica, ácido nucleico isolado, vetor de expressão, célula hospedeira, método para detectar fcrl5 em uma célula ou tecido inteiro, método para tratar câncer em um indivíduo, uso do anticorpo ou fragmento de ligação ao antígeno do mesmo, kit para tratar câncer
|
|
ES2891578T3
(es)
|
2016-04-01 |
2022-01-28 |
Kite Pharma Inc |
Antígeno quimérico y receptores de células T y métodos de uso
|
|
CN106014789A
(zh)
|
2016-06-25 |
2016-10-12 |
郭远军 |
一种悬吊式一体化反装斜击式水轮发电机及其做功方法
|
|
JP7062640B2
(ja)
|
2016-07-29 |
2022-05-06 |
ジュノー セラピューティクス インコーポレイテッド |
抗ｃｄ１９抗体に対する抗イディオタイプ抗体
|
|
WO2018067993A1
(en)
|
2016-10-07 |
2018-04-12 |
TCR2 Therapeutics Inc. |
Compositions and methods for t-cell receptors reprogramming using fusion proteins
|
|
MX2019010906A
(es)
|
2017-03-14 |
2020-02-12 |
Juno Therapeutics Inc |
Metodos para almacenamiento criogenico.
|
|
JP7339160B2
(ja)
|
2017-04-27 |
2023-09-05 |
ジュノ セラピューティクス ゲーエムベーハー |
オリゴマー粒子試薬およびその使用方法
|
|
SG11202104355SA
(en)
*
|
2018-10-31 |
2021-05-28 |
Juno Therapeutics Gmbh |
Methods for selection and stimulation of cells and apparatus for same
|
|
EP3873937A2
(en)
|
2018-11-01 |
2021-09-08 |
Juno Therapeutics, Inc. |
Chimeric antigen receptors specific for g protein-coupled receptor class c group 5 member d (gprc5d)
|
|
ES2968737T3
(es)
|
2018-11-06 |
2024-05-13 |
Juno Therapeutics Inc |
Proceso para producir células T manipuladas genéticamente
|
|
SG11202107976SA
(en)
|
2019-01-29 |
2021-08-30 |
Juno Therapeutics Inc |
Antibodies and chimeric antigen receptors specific for receptor tyrosine kinase like orphan receptor 1 (ror1)
|