|
US5800992A
(en)
|
1989-06-07 |
1998-09-01 |
Fodor; Stephen P.A. |
Method of detecting nucleic acids
|
|
US6589726B1
(en)
|
1991-09-04 |
2003-07-08 |
Metrigen, Inc. |
Method and apparatus for in situ synthesis on a solid support
|
|
US5324633A
(en)
|
1991-11-22 |
1994-06-28 |
Affymax Technologies N.V. |
Method and apparatus for measuring binding affinity
|
|
US5695934A
(en)
|
1994-10-13 |
1997-12-09 |
Lynx Therapeutics, Inc. |
Massively parallel sequencing of sorted polynucleotides
|
|
SE9601676D0
(sv)
|
1996-04-30 |
1996-04-30 |
Ulf Landegren |
Improved probing of specific mucleic acids
|
|
WO1998030575A1
(en)
|
1997-01-08 |
1998-07-16 |
Proligo Llc |
Bioconjugation of macromolecules
|
|
US5888737A
(en)
|
1997-04-15 |
1999-03-30 |
Lynx Therapeutics, Inc. |
Adaptor-based sequence analysis
|
|
US5919626A
(en)
|
1997-06-06 |
1999-07-06 |
Orchid Bio Computer, Inc. |
Attachment of unmodified nucleic acids to silanized solid phase surfaces
|
|
US20070166741A1
(en)
|
1998-12-14 |
2007-07-19 |
Somalogic, Incorporated |
Multiplexed analyses of test samples
|
|
US7427678B2
(en)
|
1998-01-08 |
2008-09-23 |
Sigma-Aldrich Co. |
Method for immobilizing oligonucleotides employing the cycloaddition bioconjugation method
|
|
US6255469B1
(en)
|
1998-05-06 |
2001-07-03 |
New York University |
Periodic two and three dimensional nucleic acid structures
|
|
JP3662850B2
(ja)
|
1998-06-24 |
2005-06-22 |
イルミナ インコーポレイテッド |
微小球を有するアレイセンサーのデコード
|
|
WO2000006770A1
(en)
|
1998-07-30 |
2000-02-10 |
Solexa Ltd. |
Arrayed biomolecules and their use in sequencing
|
|
US6824866B1
(en)
|
1999-04-08 |
2004-11-30 |
Affymetrix, Inc. |
Porous silica substrates for polymer synthesis and assays
|
|
KR100379411B1
(ko)
|
1999-06-28 |
2003-04-10 |
엘지전자 주식회사 |
바이오칩 및 그의 생체 물질 패터닝 및 측정 방법
|
|
US7306904B2
(en)
|
2000-02-18 |
2007-12-11 |
Olink Ab |
Methods and kits for proximity probing
|
|
US6806361B1
(en)
|
2000-03-17 |
2004-10-19 |
Affymetrix, Inc. |
Methods of enhancing functional performance of nucleic acid arrays
|
|
US6917726B2
(en)
|
2001-09-27 |
2005-07-12 |
Cornell Research Foundation, Inc. |
Zero-mode clad waveguides for performing spectroscopy with confined effective observation volumes
|
|
US7148058B2
(en)
|
2000-06-05 |
2006-12-12 |
Chiron Corporation |
Protein microarrays on mirrored surfaces for performing proteomic analyses
|
|
US7158224B2
(en)
|
2000-06-25 |
2007-01-02 |
Affymetrix, Inc. |
Optically active substrates
|
|
WO2003044527A1
(en)
|
2001-11-22 |
2003-05-30 |
Riken |
Substrate for biomolecule microarray, process for producing the same, biomolecule microarray and method of collecting data on biomolecule microarray
|
|
US8013134B2
(en)
|
2001-11-23 |
2011-09-06 |
Olink Ab |
Kit for proximity probing with multivalent proximity probes
|
|
US20050054118A1
(en)
|
2002-02-27 |
2005-03-10 |
Lebrun Stewart J. |
High throughput screening method
|
|
KR100455293B1
(ko)
|
2002-05-15 |
2004-11-06 |
삼성전자주식회사 |
친수성 영역과 소수성 영역으로 구성되는 생물분자용어레이 판의 제조방법
|
|
AU2003240482B2
(en)
|
2002-05-30 |
2009-03-12 |
The Scripps Research Institute |
Copper-catalysed ligation of azides and acetylenes
|
|
US20070275411A1
(en)
|
2006-05-25 |
2007-11-29 |
Mcgall Glenn H |
Silane mixtures
|
|
US20040209383A1
(en)
|
2003-04-17 |
2004-10-21 |
Industrial Technology Research Institute |
Lift-off process for protein chip
|
|
US7183054B2
(en)
|
2003-06-03 |
2007-02-27 |
President And Fellows Of Harvard College |
Assay for identifying biological targets of polynucleotide-binding compounds
|
|
US7122482B2
(en)
|
2003-10-27 |
2006-10-17 |
Molecular Imprints, Inc. |
Methods for fabricating patterned features utilizing imprint lithography
|
|
US20050095577A1
(en)
|
2003-10-31 |
2005-05-05 |
Yang Dan-Hui D. |
Protein bioarray on silane-modified substrate surface
|
|
US7259258B2
(en)
|
2003-12-17 |
2007-08-21 |
Illumina, Inc. |
Methods of attaching biological compounds to solid supports using triazine
|
|
EP1701785A1
(en)
|
2004-01-07 |
2006-09-20 |
Solexa Ltd. |
Modified molecular arrays
|
|
DE602005027700D1
(de)
|
2004-05-25 |
2011-06-09 |
Helicos Biosciences Corp |
Verfahren zur nukleinsäureimmobilisierung
|
|
US20050287523A1
(en)
|
2004-06-01 |
2005-12-29 |
The Regents Of The University Of California |
Functionalized platform for individual molecule or cell characterization
|
|
JP2008504846A
(ja)
|
2004-06-10 |
2008-02-21 |
ニューヨーク ユニバーシティ |
ポリ核酸多重交叉分子の多角形ナノ構造および二重交叉接着に基づく格子の組み立て品
|
|
US7170050B2
(en)
|
2004-09-17 |
2007-01-30 |
Pacific Biosciences Of California, Inc. |
Apparatus and methods for optical analysis of molecules
|
|
US7315019B2
(en)
|
2004-09-17 |
2008-01-01 |
Pacific Biosciences Of California, Inc. |
Arrays of optical confinements and uses thereof
|
|
GB0507835D0
(en)
|
2005-04-18 |
2005-05-25 |
Solexa Ltd |
Method and device for nucleic acid sequencing using a planar wave guide
|
|
US20090018028A1
(en)
|
2005-05-12 |
2009-01-15 |
Stuart Lindsay |
Self-Assembled Nucleic Acid Nanoarrays and Uses Therefor
|
|
US7842793B2
(en)
|
2005-06-14 |
2010-11-30 |
The California Institute Of Technology |
Methods of making nucleic acid nanostructures
|
|
JP5331476B2
(ja)
|
2005-06-15 |
2013-10-30 |
カリダ・ジェノミックス・インコーポレイテッド |
遺伝子解析および化学解析用の単分子アレイ
|
|
US7514952B2
(en)
|
2005-06-29 |
2009-04-07 |
Altera Corporation |
I/O circuitry for reducing ground bounce and VCC sag in integrated circuit devices
|
|
US8592136B2
(en)
|
2005-09-13 |
2013-11-26 |
Affymetrix, Inc. |
Methods for producing codes for microparticles
|
|
EP1941276A1
(de)
|
2005-10-29 |
2008-07-09 |
Bayer Technology Services GmbH |
Verfahren zur bestimmung eines oder mehrerer analyten in komplex zusammengesetzten proben biologischen ursprungs und dessen verwendung
|
|
US7329860B2
(en)
|
2005-11-23 |
2008-02-12 |
Illumina, Inc. |
Confocal imaging methods and apparatus
|
|
US8492098B2
(en)
|
2006-02-21 |
2013-07-23 |
The Trustees Of Tufts College |
Methods and arrays for target analyte detection and determination of reaction components that affect a reaction
|
|
GB0605584D0
(en)
|
2006-03-20 |
2006-04-26 |
Olink Ab |
Method for analyte detection using proximity probes
|
|
EP3722409A1
(en)
|
2006-03-31 |
2020-10-14 |
Illumina, Inc. |
Systems and devices for sequence by synthesis analysis
|
|
US8685894B2
(en)
*
|
2006-05-25 |
2014-04-01 |
Arizona Board Of Regents, A Body Corporate Of The State Of Arizona Acting For And On Behalf Of Arizona State University |
Modified nucleic acid nanoarrays and uses therefor
|
|
US8349167B2
(en)
|
2006-12-14 |
2013-01-08 |
Life Technologies Corporation |
Methods and apparatus for detecting molecular interactions using FET arrays
|
|
US7948015B2
(en)
|
2006-12-14 |
2011-05-24 |
Life Technologies Corporation |
Methods and apparatus for measuring analytes using large scale FET arrays
|
|
US8262900B2
(en)
|
2006-12-14 |
2012-09-11 |
Life Technologies Corporation |
Methods and apparatus for measuring analytes using large scale FET arrays
|
|
US7855054B2
(en)
|
2007-01-16 |
2010-12-21 |
Somalogic, Inc. |
Multiplexed analyses of test samples
|
|
US8975026B2
(en)
|
2007-01-16 |
2015-03-10 |
Somalogic, Inc. |
Method for generating aptamers with improved off-rates
|
|
US7947447B2
(en)
|
2007-01-16 |
2011-05-24 |
Somalogic, Inc. |
Method for generating aptamers with improved off-rates
|
|
US20110136099A1
(en)
|
2007-01-16 |
2011-06-09 |
Somalogic, Inc. |
Multiplexed Analyses of Test Samples
|
|
US7964356B2
(en)
|
2007-01-16 |
2011-06-21 |
Somalogic, Inc. |
Method for generating aptamers with improved off-rates
|
|
WO2009012340A2
(en)
|
2007-07-16 |
2009-01-22 |
California Institute Of Technology |
Microfluidic devices, methods and systems for detecting target molecules
|
|
US8404830B2
(en)
|
2007-07-17 |
2013-03-26 |
Somalogic, Inc. |
Method for generating aptamers with improved off-rates
|
|
EP2265950B1
(en)
|
2008-03-05 |
2019-01-23 |
Axela Inc. |
Detection of biomarkers and biomarker complexes
|
|
US9340416B2
(en)
*
|
2008-08-13 |
2016-05-17 |
California Institute Of Technology |
Polynucleotides and related nanoassemblies, structures, arrangements, methods and systems
|
|
US8222047B2
(en)
|
2008-09-23 |
2012-07-17 |
Quanterix Corporation |
Ultra-sensitive detection of molecules on single molecule arrays
|
|
US20100137143A1
(en)
|
2008-10-22 |
2010-06-03 |
Ion Torrent Systems Incorporated |
Methods and apparatus for measuring analytes
|
|
US8148264B2
(en)
|
2009-02-25 |
2012-04-03 |
California Institue Of Technology |
Methods for fabrication of high aspect ratio micropillars and nanopillars
|
|
US8415171B2
(en)
|
2010-03-01 |
2013-04-09 |
Quanterix Corporation |
Methods and systems for extending dynamic range in assays for the detection of molecules or particles
|
|
US8236574B2
(en)
|
2010-03-01 |
2012-08-07 |
Quanterix Corporation |
Ultra-sensitive detection of molecules or particles using beads or other capture objects
|
|
US9678068B2
(en)
|
2010-03-01 |
2017-06-13 |
Quanterix Corporation |
Ultra-sensitive detection of molecules using dual detection methods
|
|
EP3345915B1
(en)
|
2010-04-12 |
2021-11-24 |
Somalogic, Inc. |
5-position modified pyrimidines and their use
|
|
WO2011140544A2
(en)
|
2010-05-07 |
2011-11-10 |
President And Fellows Of Harvard College |
Integrated nanobeam cavity array spectrometer
|
|
US8798414B2
(en)
|
2010-09-29 |
2014-08-05 |
President And Fellows Of Harvard College |
High quality factor photonic crystal nanobeam cavity and method of designing and making same
|
|
US8951781B2
(en)
|
2011-01-10 |
2015-02-10 |
Illumina, Inc. |
Systems, methods, and apparatuses to image a sample for biological or chemical analysis
|
|
GB201101621D0
(en)
|
2011-01-31 |
2011-03-16 |
Olink Ab |
Method and product
|
|
GB2510488B
(en)
|
2011-06-23 |
2020-04-08 |
Univ Texas |
Identifying peptides at the single molecule level
|
|
WO2016069124A1
(en)
|
2014-09-15 |
2016-05-06 |
Board Of Regents, The University Of Texas System |
Improved single molecule peptide sequencing
|
|
WO2013022694A1
(en)
|
2011-08-05 |
2013-02-14 |
President And Fellows Of Harvard College |
Compositions and methods relating to nucleic acid nano-and micro-technology
|
|
US9164053B2
(en)
|
2011-09-26 |
2015-10-20 |
The Regents Of The University Of California |
Electronic device for monitoring single molecule dynamics
|
|
CA2856163C
(en)
|
2011-10-28 |
2019-05-07 |
Illumina, Inc. |
Microarray fabrication system and method
|
|
WO2013119676A1
(en)
|
2012-02-06 |
2013-08-15 |
Arizona Board Of Regents, A Body Corporate Of The State Of Arizona Acting For And On Behalf Of Arizona State University |
Novel dna-origami nanovaccines
|
|
WO2013148186A1
(en)
|
2012-03-26 |
2013-10-03 |
President And Fellows Of Harvard College |
Lipid-coated nucleic acid nanostructures of defined shape
|
|
CA2868096C
(en)
|
2012-03-28 |
2019-12-31 |
Somalogic, Inc. |
Aptamers to pdgf and vegf and their use in treating pdgf and vegf mediated conditions
|
|
EP2834622B1
(en)
|
2012-04-03 |
2023-04-12 |
Illumina, Inc. |
Integrated optoelectronic read head and fluidic cartridge useful for nucleic acid sequencing
|
|
US8765359B2
(en)
|
2012-06-05 |
2014-07-01 |
Complete Genomics, Inc. |
Method of fabricating patterned functional substrates
|
|
CN104781416B
(zh)
|
2012-07-24 |
2017-07-04 |
哈佛学院院长及董事 |
核酸纳米结构的自装配
|
|
EP3699577B1
(en)
|
2012-08-20 |
2023-11-08 |
Illumina, Inc. |
System for fluorescence lifetime based sequencing
|
|
US9410887B2
(en)
|
2012-10-05 |
2016-08-09 |
California Institute Of Technology |
Optical sensor for analyte detection
|
|
US9975916B2
(en)
|
2012-11-06 |
2018-05-22 |
President And Fellows Of Harvard College |
Compositions and methods relating to complex nucleic acid nanostructures
|
|
JP6506768B2
(ja)
|
2013-09-24 |
2019-04-24 |
ソマロジック・インコーポレーテッド |
多重アプタマー標的の検出
|
|
CN105917003A
(zh)
|
2013-11-17 |
2016-08-31 |
宽腾矽公司 |
用于生物和化学试样的快速分析的有源像素集成装置
|
|
BR112016010165A2
(pt)
|
2013-11-21 |
2017-12-05 |
Somalogic Inc |
composições de nucleotídeos modificados de citidina-5-carboxamida e métodos relacionados às mesmas
|
|
US9275871B2
(en)
|
2014-01-09 |
2016-03-01 |
Micron Technology, Inc. |
Nanostructures having low defect density and methods of forming thereof
|
|
TWI621584B
(zh)
|
2014-05-22 |
2018-04-21 |
哈佛大學校長及研究員協會 |
可縮放核酸奈米製造技術
|
|
EP3460075B1
(en)
|
2014-07-15 |
2020-11-04 |
Illumina, Inc. |
Biochemically activated electronic device
|
|
US20170212101A1
(en)
|
2014-07-18 |
2017-07-27 |
Cdi Laboratories, Inc. |
Methods and compositions to identify, quantify, and characterize target analytes and binding moieties
|
|
MX384725B
(es)
|
2014-08-08 |
2025-03-14 |
Quantum Si Inc |
Dispositivo integrado con fuente de luz externa para el sondeo, detección y análisis de moléculas.
|
|
KR102585730B1
(ko)
|
2014-08-08 |
2023-10-10 |
퀀텀-에스아이 인코포레이티드 |
수신된 광자들의 시간 비닝을 위한 집적 디바이스
|
|
CN106796175B
(zh)
|
2014-08-08 |
2021-01-05 |
宽腾矽公司 |
用于探测、检测和分析分子的光学系统和检测芯片
|
|
US9987609B2
(en)
|
2014-09-05 |
2018-06-05 |
California Institute Of Technology |
Multiplexed surface enhanced Raman sensors for early disease detection and in-situ bacterial monitoring
|
|
CN117442748A
(zh)
|
2014-10-02 |
2024-01-26 |
希望之城公司 |
多价中间表位、中间表位结合抗体及其用途
|
|
EP3009520B1
(en)
*
|
2014-10-14 |
2018-12-12 |
Karlsruher Institut für Technologie |
Site-specific immobilization of DNA origami structures on solid substrates
|
|
US10513535B2
(en)
|
2014-10-24 |
2019-12-24 |
New York University |
Self-replication of nucleic acid origami tiles
|
|
WO2016140726A2
(en)
|
2014-12-16 |
2016-09-09 |
President And Fellows Of Harvard College |
Triggered assembly of metafluorophores
|
|
JP2018500905A
(ja)
|
2014-12-18 |
2018-01-18 |
ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア |
ナノチューブを使用した核酸ポリメラーゼ立体構造変化の検出
|
|
WO2016144755A1
(en)
|
2015-03-07 |
2016-09-15 |
President And Fellows Of Harvard College |
Single-stranded dna nanostructures
|
|
US9330932B1
(en)
|
2015-03-31 |
2016-05-03 |
Micron Technology, Inc. |
Methods of fabricating features associated with semiconductor substrates
|
|
US9466504B1
(en)
|
2015-03-31 |
2016-10-11 |
Micron Technology, Inc. |
Methods of fabricating features associated with semiconductor substrates
|
|
US9881786B2
(en)
|
2015-04-02 |
2018-01-30 |
Micron Technology, Inc. |
Methods of forming nanostructures using self-assembled nucleic acids, and nanostructures thereof
|
|
US10787704B2
(en)
|
2015-05-12 |
2020-09-29 |
Illumina, Inc. |
Field-effect apparatus and methods for sequencing nucleic acids
|
|
US10605730B2
(en)
|
2015-05-20 |
2020-03-31 |
Quantum-Si Incorporated |
Optical sources for fluorescent lifetime analysis
|
|
KR102713216B1
(ko)
|
2015-06-25 |
2024-10-02 |
로스웰 엠이 아이엔씨. |
바이오분자 센서들 및 방법들
|
|
US10597767B2
(en)
|
2016-02-22 |
2020-03-24 |
Roswell Biotechnologies, Inc. |
Nanoparticle fabrication
|
|
US11235972B2
(en)
|
2016-04-11 |
2022-02-01 |
President And Fellows Of Harvard College |
Sequence design for efficient assembly of nucleic acid structures
|
|
AU2017259794B2
(en)
|
2016-05-02 |
2023-04-13 |
Encodia, Inc. |
Macromolecule analysis employing nucleic acid encoding
|
|
US9829456B1
(en)
|
2016-07-26 |
2017-11-28 |
Roswell Biotechnologies, Inc. |
Method of making a multi-electrode structure usable in molecular sensing devices
|
|
US11168320B2
(en)
|
2016-08-09 |
2021-11-09 |
Arizona Board Of Regents On Behalf Of Arizona State University |
Structure assisted directed evolution of multivalent aptamers
|
|
US10646505B2
(en)
|
2016-09-07 |
2020-05-12 |
California Institute Of Technology |
DNA-functionalized scaffolds for drug capture applications
|
|
DK3548652T3
(da)
*
|
2016-12-01 |
2024-07-08 |
Nautilus Subsidiary Inc |
Fremgangsmåder til proteinanalyse
|
|
KR102560427B1
(ko)
|
2016-12-22 |
2023-07-28 |
퀀텀-에스아이 인코포레이티드 |
직접 비닝 픽셀을 갖는 집적 광검출기
|
|
US10508296B2
(en)
|
2017-04-25 |
2019-12-17 |
Roswell Biotechnologies, Inc. |
Enzymatic circuits for molecular sensors
|
|
CN111566261B
(zh)
|
2017-08-18 |
2025-03-25 |
诺迪勒思附属公司 |
选择结合试剂的方法
|
|
US11001606B2
(en)
|
2017-08-30 |
2021-05-11 |
California Institute Of Technology |
Compositions and methods for fractal assembly of micron-scale nucleic acid structures
|
|
US11125748B2
(en)
|
2017-09-01 |
2021-09-21 |
University Of British Columbia |
Method for organizing individual molecules on a patterned substrate and structures assembled thereby
|
|
US11214795B2
(en)
|
2017-09-25 |
2022-01-04 |
California Institute Of Technology |
Bistable polynucleotide devices for the sensing and quantification of molecular events
|
|
US11721412B2
(en)
|
2017-10-23 |
2023-08-08 |
Nautilus Subsidiary, Inc. |
Methods for identifying a protein in a sample of unknown proteins
|
|
EP4372383A3
(en)
|
2017-10-23 |
2024-11-06 |
Nautilus Subsidiary, Inc. |
Methods and systems for protein identification
|
|
WO2019089846A1
(en)
|
2017-10-31 |
2019-05-09 |
Encodia, Inc. |
Methods and compositions for polypeptide analysis
|
|
MX2020004559A
(es)
|
2017-10-31 |
2020-10-05 |
Encodia Inc |
Kits para análisis utilizando codificación y/o etiqueta de ácido nucleico.
|
|
WO2019108954A1
(en)
|
2017-12-01 |
2019-06-06 |
Arizona Board Of Regents On Behalf Of Arizona State University |
Materials and methods relating to single molecule arrays
|
|
DK3498865T3
(da)
|
2017-12-14 |
2020-12-21 |
Univ Muenchen Ludwig Maximilians |
Påvisning og kvantificering af enkeltmolekyler ved hjælp af DNA-nanoteknologi i microwells
|
|
WO2019195633A1
(en)
*
|
2018-04-04 |
2019-10-10 |
Ignite Biosciences, Inc. |
Methods of generating nanoarrays and microarrays
|
|
GB201807409D0
(en)
|
2018-05-04 |
2018-06-20 |
Oxford Nanoimaging Ltd |
Assay
|
|
US20210239705A1
(en)
|
2018-06-06 |
2021-08-05 |
Nautilus Biotechnology, Inc. |
Methods and applications of protein identification
|
|
EP3884048A4
(en)
|
2018-11-20 |
2022-08-17 |
Nautilus Biotechnology, Inc. |
DESIGN AND SELECTION OF AFFINITY REAGENTS
|
|
TWI857000B
(zh)
|
2019-01-29 |
2024-10-01 |
美商伊路米納有限公司 |
流體槽以及將複合物引入至流體槽之方法
|
|
EP3699142A1
(en)
*
|
2019-02-20 |
2020-08-26 |
Instytut Chemii Fizycznej Polskiej Akademii Nauk |
Method of immobilization nucleic acid structure on surface of graphene, graphene modified by immobilization of nucleic acid structure and its use
|
|
KR20210134692A
(ko)
|
2019-02-27 |
2021-11-10 |
나노모자이크 인크. |
나노센서들 및 그것의 사용
|
|
US11814659B2
(en)
|
2019-03-11 |
2023-11-14 |
Arizona Board Of Regents On Behalf Of Arizona State University |
Tunable nanoscale cages from self-assembling DNA and protein building blocks
|
|
CA3135206A1
(en)
|
2019-04-29 |
2020-11-05 |
Pierre Indermuhle |
Methods and systems for integrated on-chip single-molecule detection
|
|
WO2020254684A1
(en)
|
2019-06-21 |
2020-12-24 |
Tilibit Nanosystems Gmbh |
Conditionally switchable nanostructure
|
|
WO2021087402A1
(en)
|
2019-10-30 |
2021-05-06 |
Nautilus Biotechnology, Inc. |
Flow cell systems and methods
|
|
IL305336B2
(en)
*
|
2021-03-11 |
2025-09-01 |
Nautilus Subsidiary Inc |
Systems and methods for preserving biomolecules
|