JP2024513972A5 - - Google Patents

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Publication number
JP2024513972A5
JP2024513972A5 JP2023562698A JP2023562698A JP2024513972A5 JP 2024513972 A5 JP2024513972 A5 JP 2024513972A5 JP 2023562698 A JP2023562698 A JP 2023562698A JP 2023562698 A JP2023562698 A JP 2023562698A JP 2024513972 A5 JP2024513972 A5 JP 2024513972A5
Authority
JP
Japan
Prior art keywords
nucleic acid
nucleotide
acid according
sense strand
antisense
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023562698A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024513972A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2022/024692 external-priority patent/WO2022221457A1/en
Publication of JP2024513972A publication Critical patent/JP2024513972A/ja
Publication of JP2024513972A5 publication Critical patent/JP2024513972A5/ja
Pending legal-status Critical Current

Links

JP2023562698A 2021-04-13 2022-04-13 Rnaサイレンシング剤および使用方法 Pending JP2024513972A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163174507P 2021-04-13 2021-04-13
US63/174,507 2021-04-13
PCT/US2022/024692 WO2022221457A1 (en) 2021-04-13 2022-04-13 Rna silencing agents and methods of use

Publications (2)

Publication Number Publication Date
JP2024513972A JP2024513972A (ja) 2024-03-27
JP2024513972A5 true JP2024513972A5 (enExample) 2025-04-09

Family

ID=83639690

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023562698A Pending JP2024513972A (ja) 2021-04-13 2022-04-13 Rnaサイレンシング剤および使用方法

Country Status (7)

Country Link
US (1) US20240191229A1 (enExample)
EP (1) EP4323376A4 (enExample)
JP (1) JP2024513972A (enExample)
CN (1) CN117425664A (enExample)
AU (1) AU2022257002A1 (enExample)
CA (1) CA3216732A1 (enExample)
WO (1) WO2022221457A1 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11597744B2 (en) 2017-06-30 2023-03-07 Sirius Therapeutics, Inc. Chiral phosphoramidite auxiliaries and methods of their use
US20240401045A1 (en) * 2021-10-01 2024-12-05 Adarx Pharmaceuticals, Inc. Angiotensinogen-modulating compositions and methods of use thereof

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8188060B2 (en) * 2008-02-11 2012-05-29 Dharmacon, Inc. Duplex oligonucleotides with enhanced functionality in gene regulation
KR101728655B1 (ko) * 2008-12-18 2017-04-19 다이서나 파마수이티컬, 인크. 유전자 발현의 특이적 억제를 위한 연장된 다이서 기질 제제 및 방법
EP2264169A1 (en) * 2009-06-15 2010-12-22 Qiagen GmbH Modified siNA
US9243246B2 (en) * 2010-08-24 2016-01-26 Sirna Therapeutics, Inc. Single-stranded RNAi agents containing an internal, non-nucleic acid spacer
KR101696704B1 (ko) * 2013-12-17 2017-01-16 주식회사 인코드젠 오프-타겟을 막기 위해 변형된 rna 간섭 유도 핵산 및 그 용도
EP3736334A1 (en) * 2014-07-16 2020-11-11 Arrowhead Pharmaceuticals, Inc. Rnai compositions to treat apoc3-related diseases
EP3234134B1 (en) * 2014-12-17 2020-05-27 ProQR Therapeutics II B.V. Targeted rna editing

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