JP2024522272A5 - - Google Patents

Info

Publication number
JP2024522272A5
JP2024522272A5 JP2023572540A JP2023572540A JP2024522272A5 JP 2024522272 A5 JP2024522272 A5 JP 2024522272A5 JP 2023572540 A JP2023572540 A JP 2023572540A JP 2023572540 A JP2023572540 A JP 2023572540A JP 2024522272 A5 JP2024522272 A5 JP 2024522272A5
Authority
JP
Japan
Prior art keywords
antisense oligonucleotide
seq
oligonucleotide according
lna
nos
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023572540A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024522272A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/EP2022/065217 external-priority patent/WO2022254021A1/en
Publication of JP2024522272A publication Critical patent/JP2024522272A/ja
Publication of JP2024522272A5 publication Critical patent/JP2024522272A5/ja
Pending legal-status Critical Current

Links

JP2023572540A 2021-06-04 2022-06-03 アデノシンキナーゼを標的とするアンチセンスオリゴヌクレオチド Pending JP2024522272A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DKPA202170290 2021-06-04
DKPA202170290 2021-06-04
PCT/EP2022/065217 WO2022254021A1 (en) 2021-06-04 2022-06-03 Antisense oligonucleotides targeting adenosine kinase

Publications (2)

Publication Number Publication Date
JP2024522272A JP2024522272A (ja) 2024-06-13
JP2024522272A5 true JP2024522272A5 (enExample) 2025-07-07

Family

ID=82196319

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023572540A Pending JP2024522272A (ja) 2021-06-04 2022-06-03 アデノシンキナーゼを標的とするアンチセンスオリゴヌクレオチド

Country Status (6)

Country Link
US (1) US20240240188A1 (enExample)
EP (1) EP4347824A1 (enExample)
JP (1) JP2024522272A (enExample)
CN (1) CN117642505A (enExample)
AU (1) AU2022287241A1 (enExample)
WO (1) WO2022254021A1 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4388096A1 (en) * 2021-08-19 2024-06-26 Neumirna Therapeutics ApS Antisense oligonucleotides targeting adenosine kinase
WO2026068729A1 (en) * 2024-09-26 2026-04-02 Neumirna Therapeutics Aps Antimir-27b for treatment of parkinson's disease

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4236812B2 (ja) 1997-09-12 2009-03-11 エクシコン エ/エス オリゴヌクレオチド類似体
KR20020013513A (ko) 1999-03-18 2002-02-20 추후제출 Xylo-lna 유사체
DE60029314T2 (de) 1999-03-24 2007-07-12 Exiqon A/S Verbesserte Synthese für -2.2.1. I Bicyclo-Nukleoside
AU7406700A (en) 1999-10-04 2001-05-10 Exiqon A/S Design of high affinity rnase h recruiting oligonucleotide
JP4413493B2 (ja) 2000-10-04 2010-02-10 サンタリス ファーマ アー/エス プリンlna類似体の改善された合成方法
ATE287413T1 (de) 2001-07-12 2005-02-15 Santaris Pharma As Verfahren zur herstellung des lna phosphoramidite
AU2003222743B2 (en) 2002-05-08 2008-12-11 Roche Innovation Center Copenhagen A/S Synthesis of locked nucleic acid derivatives
US7481672B2 (en) 2005-07-21 2009-01-27 Rosemount Tank Radar Ab Dielectric connector, DC-insulating through-connection and electronic system
WO2007031091A2 (en) 2005-09-15 2007-03-22 Santaris Pharma A/S Rna antagonist compounds for the modulation of p21 ras expression
EP2007888A2 (en) 2006-04-03 2008-12-31 Santaris Pharma A/S Pharmaceutical composition comprising anti-mirna antisense oligonucleotides
EP2753631A1 (en) 2011-09-07 2014-07-16 Marina Biotech, Inc. Synthesis and uses of nucleic acid compounds with conformationally restricted monomers
EP2773779B1 (en) * 2011-11-04 2020-10-14 Population Bio, Inc. Methods and compositions for diagnosing, prognosing, and treating neurological conditions
MX2016005855A (es) 2013-11-14 2016-07-13 Roche Innovation Ct Copenhagen As Compuestos de conjugados antisentido de apolipoproteina b (apob).
TW202503057A (zh) 2014-10-10 2025-01-16 美商艾爾妮蘭製藥公司 用於抑制hao1(羥酸氧化酶1(乙醇酸鹽氧化酶))基因表現的組合物及方法

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