JP2024511996A5 - - Google Patents

Info

Publication number
JP2024511996A5
JP2024511996A5 JP2023557285A JP2023557285A JP2024511996A5 JP 2024511996 A5 JP2024511996 A5 JP 2024511996A5 JP 2023557285 A JP2023557285 A JP 2023557285A JP 2023557285 A JP2023557285 A JP 2023557285A JP 2024511996 A5 JP2024511996 A5 JP 2024511996A5
Authority
JP
Japan
Prior art keywords
cancer
pharmaceutically acceptable
alkyl
tautomer
stereoisomer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023557285A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024511996A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2022/020700 external-priority patent/WO2022197892A1/en
Publication of JP2024511996A publication Critical patent/JP2024511996A/ja
Publication of JP2024511996A5 publication Critical patent/JP2024511996A5/ja
Pending legal-status Critical Current

Links

JP2023557285A 2021-03-17 2022-03-17 抗がん剤としてのプリン誘導体 Pending JP2024511996A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163162460P 2021-03-17 2021-03-17
US63/162,460 2021-03-17
PCT/US2022/020700 WO2022197892A1 (en) 2021-03-17 2022-03-17 Purine derivatives as anticancer agents

Publications (2)

Publication Number Publication Date
JP2024511996A JP2024511996A (ja) 2024-03-18
JP2024511996A5 true JP2024511996A5 (https=) 2025-03-26

Family

ID=81327909

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023557285A Pending JP2024511996A (ja) 2021-03-17 2022-03-17 抗がん剤としてのプリン誘導体

Country Status (11)

Country Link
US (1) US20240059689A1 (https=)
EP (1) EP4308566A1 (https=)
JP (1) JP2024511996A (https=)
KR (1) KR20240006509A (https=)
CN (1) CN117425656A (https=)
AU (1) AU2022238886A1 (https=)
BR (1) BR112023018799A2 (https=)
CA (1) CA3212292A1 (https=)
IL (1) IL305991A (https=)
MX (1) MX2023010909A (https=)
WO (1) WO2022197892A1 (https=)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL312642A (en) 2021-11-12 2024-07-01 Insilico Medicine Ip Ltd Small molecule inhibitors of ubiquitin specific protease 1 (usp1) and uses thereof
EP4430049A4 (en) * 2021-11-12 2025-12-17 Insilico Medicine Ip Ltd Small molecule inhibitors of ubiquitin-specific protease 1 (USP1) and uses thereof
TW202509030A (zh) 2023-05-08 2025-03-01 美商譚格醫療公司 化合物及使用方法
WO2024233665A1 (en) 2023-05-08 2024-11-14 Tango Therapeutics, Inc. Compounds and their use against cancer
WO2025010245A1 (en) 2023-07-06 2025-01-09 Exelixis, Inc. Fused pyrazole derivatives as usp1 inhibitors
CN117024253A (zh) * 2023-08-14 2023-11-10 江西阿尔法高科药业有限公司 一种药用级麝香草酚特定杂质的制备方法
WO2025102016A1 (en) 2023-11-10 2025-05-15 Vrise Therapeutics, Inc. Novel molecules as inhibitors of dna damage repair pathway
TW202539659A (zh) 2024-01-10 2025-10-16 美商維瑞斯治療股份有限公司 Dna損傷修復途徑的新穎抑制劑
WO2025256544A1 (zh) * 2024-06-11 2025-12-18 福建盛迪医药有限公司 一种1-氨烷基修饰的呋喃核糖衍生物的制备方法
CN119751316A (zh) * 2024-12-20 2025-04-04 江南大学 一种1-苯基三氟甲基n-(氟磺酰基)氨基甲酸酯化合物的制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI378933B (en) * 2008-10-14 2012-12-11 Daiichi Sankyo Co Ltd Morpholinopurine derivatives
CN102127070A (zh) * 2010-01-15 2011-07-20 山东轩竹医药科技有限公司 吡啶并环衍生物
JP2011236198A (ja) * 2010-04-13 2011-11-24 Daiichi Sankyo Co Ltd モルホリノプリン誘導体
CN108473495B (zh) * 2015-11-20 2022-04-12 福马治疗有限公司 作为泛素-特异性蛋白酶1抑制剂的嘌呤酮
US11485736B2 (en) * 2018-12-20 2022-11-01 KSQ Therapeutics, Inc. Substituted pyrazolopyrimidines and substituted purines and their use as ubiquitin-specific-processing protease 1 (USP1) inhibitors

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