JP2024509920A5 - - Google Patents

Info

Publication number
JP2024509920A5
JP2024509920A5 JP2023555245A JP2023555245A JP2024509920A5 JP 2024509920 A5 JP2024509920 A5 JP 2024509920A5 JP 2023555245 A JP2023555245 A JP 2023555245A JP 2023555245 A JP2023555245 A JP 2023555245A JP 2024509920 A5 JP2024509920 A5 JP 2024509920A5
Authority
JP
Japan
Prior art keywords
egfr
cancer
formulation according
seq
bispecific anti
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023555245A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024509920A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/IB2022/052009 external-priority patent/WO2022189942A1/en
Publication of JP2024509920A publication Critical patent/JP2024509920A/ja
Publication of JP2024509920A5 publication Critical patent/JP2024509920A5/ja
Pending legal-status Critical Current

Links

JP2023555245A 2021-03-09 2022-03-07 Egfr活性化変異を欠くがんの治療 Pending JP2024509920A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163158552P 2021-03-09 2021-03-09
US63/158,552 2021-03-09
PCT/IB2022/052009 WO2022189942A1 (en) 2021-03-09 2022-03-07 Treatment of cancers lacking egfr-activating mutations

Publications (2)

Publication Number Publication Date
JP2024509920A JP2024509920A (ja) 2024-03-05
JP2024509920A5 true JP2024509920A5 (cg-RX-API-DMAC10.html) 2025-03-13

Family

ID=80738936

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023555245A Pending JP2024509920A (ja) 2021-03-09 2022-03-07 Egfr活性化変異を欠くがんの治療

Country Status (13)

Country Link
US (1) US20220298248A1 (cg-RX-API-DMAC10.html)
EP (1) EP4304644A1 (cg-RX-API-DMAC10.html)
JP (1) JP2024509920A (cg-RX-API-DMAC10.html)
KR (1) KR20230156094A (cg-RX-API-DMAC10.html)
CN (1) CN116997358A (cg-RX-API-DMAC10.html)
AU (1) AU2022233518A1 (cg-RX-API-DMAC10.html)
BR (1) BR112023018278A2 (cg-RX-API-DMAC10.html)
CA (1) CA3212669A1 (cg-RX-API-DMAC10.html)
CL (2) CL2023002663A1 (cg-RX-API-DMAC10.html)
IL (1) IL305700A (cg-RX-API-DMAC10.html)
JO (1) JOP20230211A1 (cg-RX-API-DMAC10.html)
MX (1) MX2023010633A (cg-RX-API-DMAC10.html)
WO (1) WO2022189942A1 (cg-RX-API-DMAC10.html)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4204455A4 (en) 2020-08-25 2024-10-16 Janssen Biotech, Inc. Treatment of non-small cell lung cancer with egfr mutations

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0281604B1 (en) 1986-09-02 1993-03-31 Enzon Labs Inc. Single polypeptide chain binding molecules
GB9015198D0 (en) 1990-07-10 1990-08-29 Brien Caroline J O Binding substance
ATE199392T1 (de) 1992-12-04 2001-03-15 Medical Res Council Multivalente und multispezifische bindungsproteine, deren herstellung und verwendung
AUPO591797A0 (en) 1997-03-27 1997-04-24 Commonwealth Scientific And Industrial Research Organisation High avidity polyvalent and polyspecific reagents
AU2005250484B2 (en) 2004-06-04 2011-08-11 Genentech, Inc. EGFR mutations
WO2006028936A2 (en) 2004-09-02 2006-03-16 Genentech, Inc. Heteromultimeric molecules
KR101374454B1 (ko) 2005-03-31 2014-03-17 추가이 세이야쿠 가부시키가이샤 회합제어에 의한 폴리펩티드 제조방법
DE102005028778A1 (de) 2005-06-22 2006-12-28 SUNJÜT Deutschland GmbH Mehrlagige Folie mit einer Barriere- und einer antistatischen Lage
DK1999154T3 (da) 2006-03-24 2012-12-03 Merck Patent Gmbh Fremstillede heterodimere proteindomæner
WO2007147901A1 (en) 2006-06-22 2007-12-27 Novo Nordisk A/S Production of bispecific antibodies
CN101952312A (zh) 2007-07-31 2011-01-19 米迪缪尼有限公司 多特异性表位结合蛋白及其应用
US8227577B2 (en) 2007-12-21 2012-07-24 Hoffman-La Roche Inc. Bivalent, bispecific antibodies
US9266967B2 (en) 2007-12-21 2016-02-23 Hoffmann-La Roche, Inc. Bivalent, bispecific antibodies
US8242247B2 (en) 2007-12-21 2012-08-14 Hoffmann-La Roche Inc. Bivalent, bispecific antibodies
US20090162359A1 (en) 2007-12-21 2009-06-25 Christian Klein Bivalent, bispecific antibodies
US9067986B2 (en) 2009-04-27 2015-06-30 Oncomed Pharmaceuticals, Inc. Method for making heteromultimeric molecules
PT2560993T (pt) 2010-04-20 2024-09-16 Genmab As Proteínas contendo anticorpo heterodimérico fc e métodos para a produção das mesmas
CN103429620B (zh) 2010-11-05 2018-03-06 酵活有限公司 在Fc结构域中具有突变的稳定异源二聚的抗体设计
US9574010B2 (en) 2011-11-04 2017-02-21 Zymeworks Inc. Stable heterodimeric antibody design with mutations in the Fc domain
KR102373193B1 (ko) * 2012-11-21 2022-03-10 얀센 바이오테크 인코포레이티드 이중특이성 EGFR/c-Met 항체
WO2014148557A1 (ja) * 2013-03-19 2014-09-25 凸版印刷株式会社 Egfr阻害剤感受性予測方法
BR112019010020A2 (pt) 2016-11-17 2019-08-20 Univ Texas compostos com atividade anti-tumoral contra células cancerosas contendo mutações de egfr ou her2 exon 20
MX2021010265A (es) * 2019-02-26 2021-09-23 Janssen Biotech Inc Terapias de combinacion y estratificacion de pacientes con anticuerpos anti-egfr/c-met biespecificos.

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