JP2024507986A5 - - Google Patents

Info

Publication number
JP2024507986A5
JP2024507986A5 JP2023552183A JP2023552183A JP2024507986A5 JP 2024507986 A5 JP2024507986 A5 JP 2024507986A5 JP 2023552183 A JP2023552183 A JP 2023552183A JP 2023552183 A JP2023552183 A JP 2023552183A JP 2024507986 A5 JP2024507986 A5 JP 2024507986A5
Authority
JP
Japan
Prior art keywords
antibody
antibody fragment
use according
fragment
region
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023552183A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024507986A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/EP2022/055080 external-priority patent/WO2022184676A1/en
Publication of JP2024507986A publication Critical patent/JP2024507986A/ja
Publication of JP2024507986A5 publication Critical patent/JP2024507986A5/ja
Pending legal-status Critical Current

Links

JP2023552183A 2021-03-01 2022-03-01 抗体関連型移植拒絶反応の治療に使用するための抗cd38抗体 Pending JP2024507986A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP21159860 2021-03-01
EP21159860.2 2021-03-01
PCT/EP2022/055080 WO2022184676A1 (en) 2021-03-01 2022-03-01 Anti-cd38 antibodies for use in the treatment of antibody-mediated transplant rejection

Publications (2)

Publication Number Publication Date
JP2024507986A JP2024507986A (ja) 2024-02-21
JP2024507986A5 true JP2024507986A5 (enExample) 2025-03-07

Family

ID=74844778

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023552183A Pending JP2024507986A (ja) 2021-03-01 2022-03-01 抗体関連型移植拒絶反応の治療に使用するための抗cd38抗体

Country Status (12)

Country Link
US (1) US20240228654A9 (enExample)
EP (1) EP4301779A1 (enExample)
JP (1) JP2024507986A (enExample)
KR (1) KR20230154239A (enExample)
AU (1) AU2022230717A1 (enExample)
BR (1) BR112023016352A2 (enExample)
CA (1) CA3209172A1 (enExample)
CL (1) CL2023002495A1 (enExample)
IL (1) IL304692A (enExample)
MX (1) MX2023009868A (enExample)
TW (1) TW202302642A (enExample)
WO (1) WO2022184676A1 (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW202545561A (zh) * 2024-01-16 2025-12-01 德商莫菲西斯有限責任公司 抗體的高度濃縮液體製劑

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020164788A1 (en) 1994-12-02 2002-11-07 The Wellcome Foundation Limited Humanized antibodies to CD38
WO1999062526A2 (en) 1998-06-05 1999-12-09 Mayo Foundation For Medical Education And Research Use of genetically engineered antibodies to cd38 to treat multiple myeloma
US7223397B1 (en) 1999-01-07 2007-05-29 Research Development Foundation Potentiation of anti-CD38-Immunotoxin cytotoxicity
EP1174440A1 (en) 2000-07-19 2002-01-23 U-BISys B.V. A selectively-expressed epitope on the human CD38 molecule detected by a phage display library-derived human scFv antibody fragment
KR20140066259A (ko) 2004-02-06 2014-05-30 모르포시스 아게 항-cd38 인간 항체 및 그의 용도
JP5225069B2 (ja) 2005-03-23 2013-07-03 ゲンマブ エー/エス 多発性骨髄腫の治療のためのcd38に対する抗体
TW200745162A (en) 2005-05-24 2007-12-16 Morphosys Ag Generation and profiling of fully human hucal gold-derived therapeutic antibodies specific for human CD38
CA2625681C (en) 2005-10-12 2016-08-02 Morphosys Ag Generation and profiling of fully human hucal gold-derived therapeutic antibodies specific for human cd38
WO2008037257A2 (en) 2006-09-26 2008-04-03 Genmab A/S Anti-cd38 plus corticosteroids plus a non-corticosteroid chemotherapeutic for treating tumors
EP1914242A1 (en) 2006-10-19 2008-04-23 Sanofi-Aventis Novel anti-CD38 antibodies for the treatment of cancer
EP2191841A1 (en) 2008-11-28 2010-06-02 Sanofi-Aventis Antitumor combinations containing antibodies recognizing specifically CD38 and vincristine
EP2191840A1 (en) 2008-11-28 2010-06-02 Sanofi-Aventis Antitumor combinations containing antibodies recognizing specifically CD38 and melphalan
EP2191842A1 (en) 2008-11-28 2010-06-02 Sanofi-Aventis Antitumor combinations containing antibodies recognizing specifically CD38 and cytarabine
EP2191843A1 (en) 2008-11-28 2010-06-02 Sanofi-Aventis Antitumor combinations containing antibodies recognizing specifically CD38 and cyclophosphamide
US9732154B2 (en) 2014-02-28 2017-08-15 Janssen Biotech, Inc. Anti-CD38 antibodies for treatment of acute lymphoblastic leukemia
CN107406506A (zh) 2014-12-04 2017-11-28 詹森生物科技公司 用于治疗急性髓系白血病的抗cd38抗体
EA037548B1 (ru) 2015-06-24 2021-04-12 Янссен Байотек, Инк. Иммуномодуляция и лечение солидных опухолей антителами, которые специфически связывают cd38
US20190233533A1 (en) 2016-06-28 2019-08-01 Umc Utrecht Holding B.V. Treatment Of IgE-Mediated Diseases With Antibodies That Specifically Bind CD38
EP3434692A1 (en) 2017-07-24 2019-01-30 Encefa Compounds which specifically binds to cd38 for use in the treatment of neurodegenerative diseases
US20220135695A1 (en) * 2019-03-08 2022-05-05 Cedars-Sinai Medical Center Anti-cd38 agents for desensitization and treatment of antibody-mediated rejection of organ transplants
JP7687956B2 (ja) * 2019-03-15 2025-06-03 モルフォシス・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング 自己抗体介在性自己免疫疾患の処置のための、抗cd38抗体及びその医薬組成物

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