JP2024503408A - 細胞培養におけるタンパク質力価の改善方法 - Google Patents

細胞培養におけるタンパク質力価の改善方法 Download PDF

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JP2024503408A
JP2024503408A JP2023541945A JP2023541945A JP2024503408A JP 2024503408 A JP2024503408 A JP 2024503408A JP 2023541945 A JP2023541945 A JP 2023541945A JP 2023541945 A JP2023541945 A JP 2023541945A JP 2024503408 A JP2024503408 A JP 2024503408A
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antibody
cell culture
hepes
cells
antibodies
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レジナルド スミス、
サラ ニコレッティ、
ビクトル シャシロブ、
ホンシア ワン、
ジカン ウ、
アブデルカデル ザマミリ、
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Regeneron Pharmaceuticals Inc
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    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
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    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0018Culture media for cell or tissue culture
    • C12N5/0037Serum-free medium, which may still contain naturally-sourced components
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    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
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    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
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    • C12N2511/00Cells for large scale production

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JP2023541945A 2021-01-20 2022-01-19 細胞培養におけるタンパク質力価の改善方法 Pending JP2024503408A (ja)

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US202163139494P 2021-01-20 2021-01-20
US63/139,494 2021-01-20
PCT/US2022/012883 WO2022159432A1 (en) 2021-01-20 2022-01-19 Methods of improving protein titer in cell culture

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EP (1) EP4281542A1 (enExample)
JP (1) JP2024503408A (enExample)
KR (1) KR20230134117A (enExample)
CN (1) CN116761880A (enExample)
AU (1) AU2022209730A1 (enExample)
CA (1) CA3202197A1 (enExample)
IL (1) IL304111A (enExample)
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MA68845A1 (fr) 2022-06-17 2025-11-28 Apogee Therapeutics, Inc. Anticorps se liant à l'interleukine 13 et méthodes d'utilisation

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AU2022209730A9 (en) 2024-09-26
AU2022209730A1 (en) 2023-07-13
CN116761880A (zh) 2023-09-15
CA3202197A1 (en) 2022-07-28
US20250059501A1 (en) 2025-02-20
TW202233827A (zh) 2022-09-01
US12031151B2 (en) 2024-07-09
KR20230134117A (ko) 2023-09-20
EP4281542A1 (en) 2023-11-29
IL304111A (en) 2023-09-01
US20220228107A1 (en) 2022-07-21
WO2022159432A1 (en) 2022-07-28

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