JP2024502348A5 - - Google Patents
Info
- Publication number
- JP2024502348A5 JP2024502348A5 JP2023541024A JP2023541024A JP2024502348A5 JP 2024502348 A5 JP2024502348 A5 JP 2024502348A5 JP 2023541024 A JP2023541024 A JP 2023541024A JP 2023541024 A JP2023541024 A JP 2023541024A JP 2024502348 A5 JP2024502348 A5 JP 2024502348A5
- Authority
- JP
- Japan
- Prior art keywords
- grna
- ligand
- binding
- complex
- linker
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163133942P | 2021-01-05 | 2021-01-05 | |
| US63/133,942 | 2021-01-05 | ||
| PCT/US2022/011289 WO2022150367A1 (en) | 2021-01-05 | 2022-01-05 | Guide rna designs and complexes for tracr-less type v cas systems |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024502348A JP2024502348A (ja) | 2024-01-18 |
| JP2024502348A5 true JP2024502348A5 (https=) | 2025-01-10 |
Family
ID=82358156
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023541024A Pending JP2024502348A (ja) | 2021-01-05 | 2022-01-05 | Ｔｒａｃｒ不含 Ｖ型Ｃａｓシステム用のガイドＲＮＡデザインおよび複合体 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20240067983A1 (https=) |
| EP (1) | EP4274902A4 (https=) |
| JP (1) | JP2024502348A (https=) |
| CN (1) | CN117222743A (https=) |
| CA (1) | CA3207138A1 (https=) |
| WO (1) | WO2022150367A1 (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2020051562A2 (en) | 2018-09-07 | 2020-03-12 | Beam Therapeutics Inc. | Compositions and methods for improving base editing |
| EP3847254A4 (en) | 2018-09-07 | 2022-08-10 | Beam Therapeutics Inc. | COMPOSITIONS AND METHODS FOR DELIVERING A NUCLEOBASE EDITING SYSTEM |
| AU2020215730A1 (en) | 2019-01-31 | 2021-07-29 | Beam Therapeutics Inc. | Nucleobase editors having reduced non-target deamination and assays for characterizing nucleobase editors |
| CN120174005A (zh) | 2019-02-13 | 2025-06-20 | 比姆医疗股份有限公司 | 具有用于修饰靶标序列中核碱基的腺苷脱氨酶碱基编辑器的经修饰的免疫细胞 |
| EP4034138A4 (en) | 2019-09-27 | 2024-07-31 | Beam Therapeutics, Inc. | COMPOSITIONS AND METHODS FOR THE TREATMENT OF LIQUID CANCERS |
| CA3196831A1 (en) | 2020-09-25 | 2022-03-31 | Beam Therapeutics Inc. | Fratricide resistant modified immune cells and methods of using the same |
| WO2025212120A1 (en) * | 2024-04-05 | 2025-10-09 | Arbor Biotechnologies, Inc. | Chemical modifications of guide rnas for crispr nucleases |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP7044373B2 (ja) * | 2015-07-15 | 2022-03-30 | ラトガース，ザ ステート ユニバーシティ オブ ニュージャージー | ヌクレアーゼ非依存的な標的化遺伝子編集プラットフォームおよびその用途 |
| EP4485466A3 (en) * | 2016-08-17 | 2025-04-02 | The Broad Institute Inc. | Novel crispr enzymes and systems |
| AU2019265019B2 (en) * | 2018-05-11 | 2025-11-06 | Beam Therapeutics Inc. | Methods of substituting pathogenic amino acids using programmable base editor systems |
| MX2021010559A (es) * | 2019-03-07 | 2021-12-15 | Univ California | Polipéptidos efectores de crispr-cas y métodos de uso de estos. |
| US12286633B2 (en) * | 2019-12-17 | 2025-04-29 | University Of Maryland, College Park | Compositions and methods for genome editing in plants |
-
2022
- 2022-01-05 JP JP2023541024A patent/JP2024502348A/ja active Pending
- 2022-01-05 CN CN202280019316.8A patent/CN117222743A/zh active Pending
- 2022-01-05 WO PCT/US2022/011289 patent/WO2022150367A1/en not_active Ceased
- 2022-01-05 EP EP22737034.3A patent/EP4274902A4/en active Pending
- 2022-01-05 CA CA3207138A patent/CA3207138A1/en active Pending
- 2022-01-05 US US18/270,740 patent/US20240067983A1/en active Pending
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