JP2024523877A5 - - Google Patents

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Publication number
JP2024523877A5
JP2024523877A5 JP2023577378A JP2023577378A JP2024523877A5 JP 2024523877 A5 JP2024523877 A5 JP 2024523877A5 JP 2023577378 A JP2023577378 A JP 2023577378A JP 2023577378 A JP2023577378 A JP 2023577378A JP 2024523877 A5 JP2024523877 A5 JP 2024523877A5
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JP
Japan
Prior art keywords
ssrna
adar
rna
sensor
synthetic
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JP2023577378A
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English (en)
Japanese (ja)
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JP7795747B2 (ja
JP2024523877A (ja
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Priority claimed from PCT/US2022/033459 external-priority patent/WO2022266117A2/en
Publication of JP2024523877A publication Critical patent/JP2024523877A/ja
Publication of JP2024523877A5 publication Critical patent/JP2024523877A5/ja
Application granted granted Critical
Publication of JP7795747B2 publication Critical patent/JP7795747B2/ja
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JP2023577378A 2021-06-15 2022-06-14 デアミナーゼベースのrnaセンサー Active JP7795747B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202163210829P 2021-06-15 2021-06-15
US63/210,829 2021-06-15
US202263267177P 2022-01-26 2022-01-26
US63/267,177 2022-01-26
PCT/US2022/033459 WO2022266117A2 (en) 2021-06-15 2022-06-14 Deaminase-based rna sensors

Publications (3)

Publication Number Publication Date
JP2024523877A JP2024523877A (ja) 2024-07-02
JP2024523877A5 true JP2024523877A5 (https=) 2025-06-11
JP7795747B2 JP7795747B2 (ja) 2026-01-08

Family

ID=84527393

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023577378A Active JP7795747B2 (ja) 2021-06-15 2022-06-14 デアミナーゼベースのrnaセンサー

Country Status (9)

Country Link
US (2) US12195734B2 (https=)
EP (1) EP4355906A2 (https=)
JP (1) JP7795747B2 (https=)
KR (1) KR20240021893A (https=)
AU (1) AU2022291759A1 (https=)
CA (1) CA3222560A1 (https=)
IL (1) IL309025B1 (https=)
MX (1) MX2023014550A (https=)
WO (1) WO2022266117A2 (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2024004934A (es) * 2021-10-29 2024-09-10 Duke Univeristy Composiciones y sistemas para la edicion de celulas programables por arn y metodos para elaborar y usar los mismos.
KR20240155250A (ko) * 2022-02-24 2024-10-28 더 보드 오브 트러스티스 오브 더 리랜드 스탠포드 쥬니어 유니버시티 감각 반응 응용을 위해 adar 편집을 이용하는 살아있는 세포의 rna 센서
JPWO2024071424A1 (https=) 2022-09-29 2024-04-04
JP7847274B2 (ja) * 2022-10-27 2026-04-16 アリゾナ ボード オブ リージェンツ オン ビハーフ オブ アリゾナ ステート ユニバーシティ 核酸センサーに関連する組成物および方法
WO2025054355A1 (en) * 2023-09-06 2025-03-13 Radar Therapeutics Inc. Methods, systems, and compositions for exogenous control of protein expression
WO2025151800A1 (en) 2024-01-10 2025-07-17 Autonomous Therapeutics, Inc. Programmable, rna editor-controlled nucleic acid dose amplifiers and their methods of use
CN119505015B (zh) * 2024-11-15 2025-10-17 北京大学 一种融合蛋白及其应用方法
CN121344095B (zh) * 2025-12-16 2026-04-28 北京肿瘤医院(北京大学肿瘤医院) 一种细胞内mRNA传感器开关的DNA文库筛选方法及应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015120197A1 (en) * 2014-02-05 2015-08-13 Regents Of The University Of California Rna editing biomarkers for diagnosis, pharmacological screening and prognostication in cancer
CN110612353A (zh) * 2017-03-03 2019-12-24 加利福尼亚大学董事会 经由抑制性tRNAs和脱氨酶对突变进行RNA靶向
US11359247B2 (en) * 2017-07-31 2022-06-14 Massachusetts Institute Of Technology High performance multi-input microRNA sensors and uses thereof
WO2019071048A1 (en) * 2017-10-04 2019-04-11 The Broad Institute, Inc. SYSTEMS, METHODS AND COMPOSITIONS FOR TARGETED NUCLEIC ACID EDITION
EP3864152B1 (en) * 2018-10-12 2023-08-16 Peking University Methods and compositions for editing rnas
WO2022003684A1 (en) * 2020-06-29 2022-01-06 Bar-Ilan University Composition and methods for identifying antisense guide rna for rna editing
MX2024004934A (es) * 2021-10-29 2024-09-10 Duke Univeristy Composiciones y sistemas para la edicion de celulas programables por arn y metodos para elaborar y usar los mismos.
KR20240155250A (ko) * 2022-02-24 2024-10-28 더 보드 오브 트러스티스 오브 더 리랜드 스탠포드 쥬니어 유니버시티 감각 반응 응용을 위해 adar 편집을 이용하는 살아있는 세포의 rna 센서

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