JP2022534813A5 - - Google Patents

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Publication number
JP2022534813A5
JP2022534813A5 JP2022515977A JP2022515977A JP2022534813A5 JP 2022534813 A5 JP2022534813 A5 JP 2022534813A5 JP 2022515977 A JP2022515977 A JP 2022515977A JP 2022515977 A JP2022515977 A JP 2022515977A JP 2022534813 A5 JP2022534813 A5 JP 2022534813A5
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JP
Japan
Application number
JP2022515977A
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Japanese (ja)
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JP2022534813A (ja
JPWO2020237217A5 (https=
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Publication date
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Priority claimed from PCT/US2020/034391 external-priority patent/WO2020237217A1/en
Publication of JP2022534813A publication Critical patent/JP2022534813A/ja
Publication of JP2022534813A5 publication Critical patent/JP2022534813A5/ja
Publication of JPWO2020237217A5 publication Critical patent/JPWO2020237217A5/ja
Pending legal-status Critical Current

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JP2022515977A 2019-05-23 2020-05-22 Cd33改変のための組成物および方法 Pending JP2022534813A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201962852238P 2019-05-23 2019-05-23
US62/852,238 2019-05-23
US202062962127P 2020-01-16 2020-01-16
US62/962,127 2020-01-16
PCT/US2020/034391 WO2020237217A1 (en) 2019-05-23 2020-05-22 Compositions and methods for cd33 modification

Publications (3)

Publication Number Publication Date
JP2022534813A JP2022534813A (ja) 2022-08-03
JP2022534813A5 true JP2022534813A5 (https=) 2023-05-24
JPWO2020237217A5 JPWO2020237217A5 (https=) 2023-05-24

Family

ID=71078652

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022515977A Pending JP2022534813A (ja) 2019-05-23 2020-05-22 Cd33改変のための組成物および方法

Country Status (9)

Country Link
US (1) US20220228153A1 (https=)
EP (1) EP3973057A1 (https=)
JP (1) JP2022534813A (https=)
KR (1) KR20220035877A (https=)
CN (1) CN114423865A (https=)
AU (1) AU2020280103A1 (https=)
CA (1) CA3141732A1 (https=)
MX (1) MX2021014306A (https=)
WO (1) WO2020237217A1 (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG11201907870VA (en) 2017-02-28 2019-09-27 Vor Biopharma Inc Compositions and methods for inhibition of lineage specific proteins
CA3110837A1 (en) * 2018-08-28 2020-03-05 Vor Biopharma Inc. Genetically engineered hematopoietic stem cells and uses thereof
US20230407337A1 (en) * 2020-12-08 2023-12-21 The Regents if the University of California Crispr ribonucleoprotein complex genome editing of human innate immune cells
US20240384304A1 (en) 2021-07-06 2024-11-21 Vor Biopharma Inc. Inhibitor oligonucleotides and methods of use thereof
AU2022324093A1 (en) 2021-08-02 2024-02-08 Vor Biopharma Inc. Compositions and methods for gene modification
WO2024015925A2 (en) 2022-07-13 2024-01-18 Vor Biopharma Inc. Compositions and methods for artificial protospacer adjacent motif (pam) generation
WO2024073751A1 (en) 2022-09-29 2024-04-04 Vor Biopharma Inc. Methods and compositions for gene modification and enrichment
WO2025030010A1 (en) 2023-08-01 2025-02-06 Vor Biopharma Inc. Compositions comprising genetically engineered hematopoietic stem cells and methods of use thereof

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3241902B1 (en) 2012-05-25 2018-02-28 The Regents of The University of California Methods and compositions for rna-directed target dna modification and for rna-directed modulation of transcription
WO2014093694A1 (en) 2012-12-12 2014-06-19 The Broad Institute, Inc. Crispr-cas nickase systems, methods and compositions for sequence manipulation in eukaryotes
EP3556858A3 (en) 2014-04-09 2020-01-22 Editas Medicine, Inc. Crispr/cas-related methods and compositions for treating cystic fibrosis
US10900034B2 (en) * 2014-12-03 2021-01-26 Agilent Technologies, Inc. Guide RNA with chemical modifications
EP3280803B1 (en) 2015-04-06 2021-05-26 The Board of Trustees of the Leland Stanford Junior University Chemically modified guide rnas for crispr/cas-mediated gene regulation
WO2017053729A1 (en) * 2015-09-25 2017-03-30 The Board Of Trustees Of The Leland Stanford Junior University Nuclease-mediated genome editing of primary cells and enrichment thereof
CN108290939B (zh) * 2015-10-16 2023-01-13 纽约市哥伦比亚大学理事会 用于抑制谱系特异性抗原的组合物和方法
JP7109784B2 (ja) 2015-10-23 2022-08-01 プレジデント アンド フェローズ オブ ハーバード カレッジ 遺伝子編集のための進化したCas9蛋白質
US10767175B2 (en) 2016-06-08 2020-09-08 Agilent Technologies, Inc. High specificity genome editing using chemically modified guide RNAs
AU2017388753A1 (en) 2016-12-30 2019-07-11 Editas Medicine, Inc. Synthetic guide molecules, compositions and methods relating thereto
SG11201907870VA (en) 2017-02-28 2019-09-27 Vor Biopharma Inc Compositions and methods for inhibition of lineage specific proteins
JP2020510439A (ja) 2017-03-10 2020-04-09 プレジデント アンド フェローズ オブ ハーバード カレッジ シトシンからグアニンへの塩基編集因子
CA3057192A1 (en) 2017-03-23 2018-09-27 President And Fellows Of Harvard College Nucleobase editors comprising nucleic acid programmable dna binding proteins
US11718659B2 (en) * 2017-08-28 2023-08-08 The Trustees Of Columbia University In The City Of New York CD33 exon 2 deficient donor stem cells for use with CD33 targeting agents
CA3110837A1 (en) * 2018-08-28 2020-03-05 Vor Biopharma Inc. Genetically engineered hematopoietic stem cells and uses thereof
SG11202103832SA (en) * 2018-11-07 2021-05-28 Crispr Therapeutics Ag Anti-cd33 immune cell cancer therapy
MX2021008490A (es) * 2019-01-16 2021-09-28 Univ Columbia Composiciones y metodos para la inhibicion de antigenos con especificidad de linaje.

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