JP2023541458A5 - - Google Patents

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Publication number
JP2023541458A5
JP2023541458A5 JP2023516770A JP2023516770A JP2023541458A5 JP 2023541458 A5 JP2023541458 A5 JP 2023541458A5 JP 2023516770 A JP2023516770 A JP 2023516770A JP 2023516770 A JP2023516770 A JP 2023516770A JP 2023541458 A5 JP2023541458 A5 JP 2023541458A5
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JP
Japan
Application number
JP2023516770A
Other languages
Japanese (ja)
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JPWO2022056459A5 (https=
JP2023541458A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2021/050254 external-priority patent/WO2022056459A1/en
Publication of JP2023541458A publication Critical patent/JP2023541458A/ja
Publication of JPWO2022056459A5 publication Critical patent/JPWO2022056459A5/ja
Publication of JP2023541458A5 publication Critical patent/JP2023541458A5/ja
Abandoned legal-status Critical Current

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JP2023516770A 2020-09-14 2021-09-14 Cd5修飾のための化合物および方法 Abandoned JP2023541458A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202063078137P 2020-09-14 2020-09-14
US63/078,137 2020-09-14
PCT/US2021/050254 WO2022056459A1 (en) 2020-09-14 2021-09-14 Compositions and methods for cd5 modification

Publications (3)

Publication Number Publication Date
JP2023541458A JP2023541458A (ja) 2023-10-02
JPWO2022056459A5 JPWO2022056459A5 (https=) 2024-09-25
JP2023541458A5 true JP2023541458A5 (https=) 2024-09-25

Family

ID=78086070

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023516770A Abandoned JP2023541458A (ja) 2020-09-14 2021-09-14 Cd5修飾のための化合物および方法

Country Status (4)

Country Link
US (1) US20240041932A1 (https=)
EP (1) EP4211245A1 (https=)
JP (1) JP2023541458A (https=)
WO (1) WO2022056459A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20250295695A1 (en) * 2022-04-04 2025-09-25 Vor Biopharma Inc. Compositions and methods for mediating epitope engineering
EP4587570A2 (en) * 2022-09-16 2025-07-23 Arsenal Biosciences, Inc. Immune cells with combination gene perturbations
KR20260051108A (ko) * 2023-05-23 2026-04-15 비토리아 바이오테라퓨틱스, 인코포레이티드. Cd5 유전자좌 영역에 삽입된 이종성 핵산 분자를 포함하는 유전자 변형 세포

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080254027A1 (en) 2002-03-01 2008-10-16 Bernett Matthew J Optimized CD5 antibodies and methods of using the same
WO2008121160A2 (en) 2006-11-21 2008-10-09 Xencor, Inc. Optimized antibodies that target cd5
MX2011000970A (es) 2008-08-29 2011-03-15 Symphogen As Anticuerpos anti-cd5.
EP3241902B1 (en) 2012-05-25 2018-02-28 The Regents of The University of California Methods and compositions for rna-directed target dna modification and for rna-directed modulation of transcription
WO2014093694A1 (en) 2012-12-12 2014-06-19 The Broad Institute, Inc. Crispr-cas nickase systems, methods and compositions for sequence manipulation in eukaryotes
EP3556858A3 (en) 2014-04-09 2020-01-22 Editas Medicine, Inc. Crispr/cas-related methods and compositions for treating cystic fibrosis
US10900034B2 (en) 2014-12-03 2021-01-26 Agilent Technologies, Inc. Guide RNA with chemical modifications
EP3280803B1 (en) 2015-04-06 2021-05-26 The Board of Trustees of the Leland Stanford Junior University Chemically modified guide rnas for crispr/cas-mediated gene regulation
CN108290939B (zh) 2015-10-16 2023-01-13 纽约市哥伦比亚大学理事会 用于抑制谱系特异性抗原的组合物和方法
JP7109784B2 (ja) 2015-10-23 2022-08-01 プレジデント アンド フェローズ オブ ハーバード カレッジ 遺伝子編集のための進化したCas9蛋白質
US10767175B2 (en) 2016-06-08 2020-09-08 Agilent Technologies, Inc. High specificity genome editing using chemically modified guide RNAs
AU2017388753A1 (en) 2016-12-30 2019-07-11 Editas Medicine, Inc. Synthetic guide molecules, compositions and methods relating thereto
SG11201907870VA (en) 2017-02-28 2019-09-27 Vor Biopharma Inc Compositions and methods for inhibition of lineage specific proteins
JP2020510439A (ja) 2017-03-10 2020-04-09 プレジデント アンド フェローズ オブ ハーバード カレッジ シトシンからグアニンへの塩基編集因子
CA3057192A1 (en) 2017-03-23 2018-09-27 President And Fellows Of Harvard College Nucleobase editors comprising nucleic acid programmable dna binding proteins
JP2020525537A (ja) * 2017-06-12 2020-08-27 エモリー ユニバーシティー T細胞抗原標的キメラ抗原受容体(car)、及び細胞療法での使用
US11718659B2 (en) 2017-08-28 2023-08-08 The Trustees Of Columbia University In The City Of New York CD33 exon 2 deficient donor stem cells for use with CD33 targeting agents
CN111918877A (zh) 2018-03-14 2020-11-10 美国卫生和人力服务部 抗cd33嵌合抗原受体及其用途
SG11202011383VA (en) * 2018-05-31 2020-12-30 Univ Washington Chimeric antigen receptor t cells (car-t) for the treatment of cancer
CN112823011A (zh) * 2018-07-09 2021-05-18 加利福尼亚大学董事会 基于t细胞的免疫疗法的基因靶标
CA3107383A1 (en) 2018-07-23 2020-01-30 Magenta Therapeutics, Inc. Use of anti-cd5 antibody drug conjugate (adc) in allogeneic cell therapy
US20220133790A1 (en) * 2019-01-16 2022-05-05 Beam Therapeutics Inc. Modified immune cells having enhanced anti-neoplasia activity and immunosuppression resistance
EP4034138A4 (en) * 2019-09-27 2024-07-31 Beam Therapeutics, Inc. COMPOSITIONS AND METHODS FOR THE TREATMENT OF LIQUID CANCERS

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