JP2022534813A - Ｃｄ３３改変のための組成物および方法 - Google Patents

Ｃｄ３３改変のための組成物および方法 Download PDF

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JP2022534813A
JP2022534813A JP2022515977A JP2022515977A JP2022534813A JP 2022534813 A JP2022534813 A JP 2022534813A JP 2022515977 A JP2022515977 A JP 2022515977A JP 2022515977 A JP2022515977 A JP 2022515977A JP 2022534813 A JP2022534813 A JP 2022534813A
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cells
grna
cell
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seq
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JPWO2020237217A5 (https=
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ライダード，ジョン
ミシュラ，ビブ，プラサド
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Vor Biopharma Inc
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    • C12N2510/00—Genetically modified cells

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JP2022515977A 2019-05-23 2020-05-22 Ｃｄ３３改変のための組成物および方法 Pending JP2022534813A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201962852238P 2019-05-23 2019-05-23
US62/852,238 2019-05-23
US202062962127P 2020-01-16 2020-01-16
US62/962,127 2020-01-16
PCT/US2020/034391 WO2020237217A1 (en) 2019-05-23 2020-05-22 Compositions and methods for cd33 modification

Publications (3)

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JP2022534813A true JP2022534813A (ja) 2022-08-03
JP2022534813A5 JP2022534813A5 (https=) 2023-05-24
JPWO2020237217A5 JPWO2020237217A5 (https=) 2023-05-24

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US (1) US20220228153A1 (https=)
EP (1) EP3973057A1 (https=)
JP (1) JP2022534813A (https=)
KR (1) KR20220035877A (https=)
CN (1) CN114423865A (https=)
AU (1) AU2020280103A1 (https=)
CA (1) CA3141732A1 (https=)
MX (1) MX2021014306A (https=)
WO (1) WO2020237217A1 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2024019176A (ja) * 2017-02-28 2024-02-08 ブイオーアール バイオファーマ インコーポレーテッド 系統特異的タンパク質の阻害のための組成物および方法

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CA3110837A1 (en) * 2018-08-28 2020-03-05 Vor Biopharma Inc. Genetically engineered hematopoietic stem cells and uses thereof
US20230407337A1 (en) * 2020-12-08 2023-12-21 The Regents if the University of California Crispr ribonucleoprotein complex genome editing of human innate immune cells
US20240384304A1 (en) 2021-07-06 2024-11-21 Vor Biopharma Inc. Inhibitor oligonucleotides and methods of use thereof
AU2022324093A1 (en) 2021-08-02 2024-02-08 Vor Biopharma Inc. Compositions and methods for gene modification
WO2024015925A2 (en) 2022-07-13 2024-01-18 Vor Biopharma Inc. Compositions and methods for artificial protospacer adjacent motif (pam) generation
WO2024073751A1 (en) 2022-09-29 2024-04-04 Vor Biopharma Inc. Methods and compositions for gene modification and enrichment
WO2025030010A1 (en) 2023-08-01 2025-02-06 Vor Biopharma Inc. Compositions comprising genetically engineered hematopoietic stem cells and methods of use thereof

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JP2017537626A (ja) * 2014-12-03 2017-12-21 アジレント・テクノロジーズ・インクＡｇｉｌｅｎｔ Ｔｅｃｈｎｏｌｏｇｉｅｓ， Ｉｎｃ． 化学修飾を有するガイドｒｎａ
JP2018531260A (ja) * 2015-10-16 2018-10-25 ザ・トラスティーズ・オブ・コロンビア・ユニバーシティ・イン・ザ・シティ・オブ・ニューヨーク 系統特異的抗原の阻害のための組成物および方法
WO2019046285A1 (en) * 2017-08-28 2019-03-07 The Trustees Of Columbia University In The City Of New York CD33 EXON 2 DONOR STEM CELLS FOR USE WITH CD33 TARGETING AGENTS
WO2020047164A1 (en) * 2018-08-28 2020-03-05 Vor Biopharma, Inc Genetically engineered hematopoietic stem cells and uses thereof
WO2020095107A1 (en) * 2018-11-07 2020-05-14 Crispr Therapeutics Ag Anti-cd33 immune cell cancer therapy
WO2020150478A1 (en) * 2019-01-16 2020-07-23 The Trustees Of Columbia University In The City Of New York Compositions and methods for inhibition of lineage specific antigens

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WO2014093694A1 (en) 2012-12-12 2014-06-19 The Broad Institute, Inc. Crispr-cas nickase systems, methods and compositions for sequence manipulation in eukaryotes
EP3556858A3 (en) 2014-04-09 2020-01-22 Editas Medicine, Inc. Crispr/cas-related methods and compositions for treating cystic fibrosis
EP3280803B1 (en) 2015-04-06 2021-05-26 The Board of Trustees of the Leland Stanford Junior University Chemically modified guide rnas for crispr/cas-mediated gene regulation
WO2017053729A1 (en) * 2015-09-25 2017-03-30 The Board Of Trustees Of The Leland Stanford Junior University Nuclease-mediated genome editing of primary cells and enrichment thereof
JP7109784B2 (ja) 2015-10-23 2022-08-01 プレジデント アンド フェローズ オブ ハーバード カレッジ 遺伝子編集のための進化したＣａｓ９蛋白質
US10767175B2 (en) 2016-06-08 2020-09-08 Agilent Technologies, Inc. High specificity genome editing using chemically modified guide RNAs
AU2017388753A1 (en) 2016-12-30 2019-07-11 Editas Medicine, Inc. Synthetic guide molecules, compositions and methods relating thereto
SG11201907870VA (en) 2017-02-28 2019-09-27 Vor Biopharma Inc Compositions and methods for inhibition of lineage specific proteins
JP2020510439A (ja) 2017-03-10 2020-04-09 プレジデント アンド フェローズ オブ ハーバード カレッジ シトシンからグアニンへの塩基編集因子
CA3057192A1 (en) 2017-03-23 2018-09-27 President And Fellows Of Harvard College Nucleobase editors comprising nucleic acid programmable dna binding proteins

Patent Citations (6)

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Publication number Priority date Publication date Assignee Title
JP2017537626A (ja) * 2014-12-03 2017-12-21 アジレント・テクノロジーズ・インクＡｇｉｌｅｎｔ Ｔｅｃｈｎｏｌｏｇｉｅｓ， Ｉｎｃ． 化学修飾を有するガイドｒｎａ
JP2018531260A (ja) * 2015-10-16 2018-10-25 ザ・トラスティーズ・オブ・コロンビア・ユニバーシティ・イン・ザ・シティ・オブ・ニューヨーク 系統特異的抗原の阻害のための組成物および方法
WO2019046285A1 (en) * 2017-08-28 2019-03-07 The Trustees Of Columbia University In The City Of New York CD33 EXON 2 DONOR STEM CELLS FOR USE WITH CD33 TARGETING AGENTS
WO2020047164A1 (en) * 2018-08-28 2020-03-05 Vor Biopharma, Inc Genetically engineered hematopoietic stem cells and uses thereof
WO2020095107A1 (en) * 2018-11-07 2020-05-14 Crispr Therapeutics Ag Anti-cd33 immune cell cancer therapy
WO2020150478A1 (en) * 2019-01-16 2020-07-23 The Trustees Of Columbia University In The City Of New York Compositions and methods for inhibition of lineage specific antigens

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2024019176A (ja) * 2017-02-28 2024-02-08 ブイオーアール バイオファーマ インコーポレーテッド 系統特異的タンパク質の阻害のための組成物および方法

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US20220228153A1 (en) 2022-07-21
CA3141732A1 (en) 2020-11-26
KR20220035877A (ko) 2022-03-22
CN114423865A (zh) 2022-04-29
EP3973057A1 (en) 2022-03-30
WO2020237217A1 (en) 2020-11-26
MX2021014306A (es) 2022-03-11
AU2020280103A1 (en) 2021-12-23

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