JP2024501658A5 - - Google Patents
Info
- Publication number
- JP2024501658A5 JP2024501658A5 JP2023537923A JP2023537923A JP2024501658A5 JP 2024501658 A5 JP2024501658 A5 JP 2024501658A5 JP 2023537923 A JP2023537923 A JP 2023537923A JP 2023537923 A JP2023537923 A JP 2023537923A JP 2024501658 A5 JP2024501658 A5 JP 2024501658A5
- Authority
- JP
- Japan
- Prior art keywords
- isomer
- salt
- inhibitors
- flt3
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063129895P | 2020-12-23 | 2020-12-23 | |
| US63/129,895 | 2020-12-23 | ||
| PCT/US2021/065037 WO2022140647A1 (en) | 2020-12-23 | 2021-12-23 | Multi-cyclic irak and flt3 inhibiting compounds and uses thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024501658A JP2024501658A (ja) | 2024-01-15 |
| JP2024501658A5 true JP2024501658A5 (https=) | 2025-01-07 |
Family
ID=82158501
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023537923A Pending JP2024501658A (ja) | 2020-12-23 | 2021-12-23 | 多環状ｉｒａｋ及びｆｌｔ３阻害化合物、並びにその使用 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US12612410B2 (https=) |
| EP (1) | EP4267142A4 (https=) |
| JP (1) | JP2024501658A (https=) |
| CN (1) | CN117015380A (https=) |
| AU (1) | AU2021410783A1 (https=) |
| CA (1) | CA3201841A1 (https=) |
| IL (1) | IL303887A (https=) |
| MX (1) | MX2023006938A (https=) |
| WO (1) | WO2022140647A1 (https=) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2023250431A2 (en) * | 2022-06-22 | 2023-12-28 | Children's Hospital Medical Center | Multi-cyclic irak and flt3 inhibiting compounds and uses thereof |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2009507032A (ja) * | 2005-09-02 | 2009-02-19 | アボット・ラボラトリーズ | 新規なイミダゾ系複素環 |
| BRPI1014572B8 (pt) * | 2009-04-16 | 2022-07-19 | Fundacion Centro Nac De Investigaciones Oncologicas Carlos Iii | Imidazopirazinas para uso como inibidores de cinase |
| WO2012052745A1 (en) | 2010-10-21 | 2012-04-26 | Centro Nacional De Investigaciones Oncológicas (Cnio) | Combinations of pi3k inhibitors with a second anti -tumor agent |
| US8673905B2 (en) * | 2011-03-17 | 2014-03-18 | Hoffmann-La Roche Inc. | Imidazo pyrazines |
| WO2014210255A1 (en) | 2013-06-26 | 2014-12-31 | Abbvie Inc. | Primary carboxamides as btk inhibitors |
| WO2015076800A1 (en) | 2013-11-21 | 2015-05-28 | Ptc Therapeutics, Inc. | Substituted pyridine and pyrazine bmi-1 inhibitors |
| US10138248B2 (en) * | 2016-06-24 | 2018-11-27 | Incyte Corporation | Substituted imidazo[2,1-f][1,2,4]triazines, substituted imidazo[1,2-a]pyridines, substituted imidazo[1,2-b]pyridazines and substituted imidazo[1,2-a]pyrazines as PI3K-γ inhibitors |
| US11542261B2 (en) * | 2016-08-17 | 2023-01-03 | Children's Hospital Medical Center | Substituted Imidazo[1,2-a]-pyridines as IRAK 1/4 and FLT3 inhibitors |
| US11254667B2 (en) | 2016-08-17 | 2022-02-22 | Children's Hospital Medical Center | Substituted imidazo[1,2-A]pyridines as IRAK 1/4 and flt3 inhibitors |
| DK3500571T3 (da) * | 2016-08-17 | 2021-03-08 | Childrens Hospital Med Ct | Imidazo[1,2-a]pyridinforbindelser, sammensætninger omfattende disse, fremgangsmåder til behandling af sygdomme ved hjælp af disse og fremgangsmåder til fremstilling heraf |
| TW201822764A (zh) * | 2016-09-14 | 2018-07-01 | 美商基利科學股份有限公司 | Syk抑制劑 |
| TW201841916A (zh) | 2017-04-12 | 2018-12-01 | 美商麥珍塔治療學股份有限公司 | 芳香烴受體拮抗劑及其用途 |
| WO2019002606A1 (en) * | 2017-06-30 | 2019-01-03 | Selvita S.A. | ADENOSINE A2A RECEPTOR 5,6-BICYCLO-IMIDAZO [1,2-A] PYRAZINE MODULATORS |
-
2021
- 2021-12-23 CA CA3201841A patent/CA3201841A1/en active Pending
- 2021-12-23 AU AU2021410783A patent/AU2021410783A1/en active Pending
- 2021-12-23 IL IL303887A patent/IL303887A/en unknown
- 2021-12-23 WO PCT/US2021/065037 patent/WO2022140647A1/en not_active Ceased
- 2021-12-23 US US18/258,586 patent/US12612410B2/en active Active
- 2021-12-23 CN CN202180093913.0A patent/CN117015380A/zh active Pending
- 2021-12-23 JP JP2023537923A patent/JP2024501658A/ja active Pending
- 2021-12-23 EP EP21912215.7A patent/EP4267142A4/en active Pending
- 2021-12-23 MX MX2023006938A patent/MX2023006938A/es unknown
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