JP2021530513A5 - - Google Patents
Info
- Publication number
- JP2021530513A5 JP2021530513A5 JP2021502436A JP2021502436A JP2021530513A5 JP 2021530513 A5 JP2021530513 A5 JP 2021530513A5 JP 2021502436 A JP2021502436 A JP 2021502436A JP 2021502436 A JP2021502436 A JP 2021502436A JP 2021530513 A5 JP2021530513 A5 JP 2021530513A5
- Authority
- JP
- Japan
- Prior art keywords
- oxazepan
- carboxamide
- ethyl
- cyano
- phenyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862699491P | 2018-07-17 | 2018-07-17 | |
| US62/699,491 | 2018-07-17 | ||
| PCT/US2019/042026 WO2020018551A1 (en) | 2018-07-17 | 2019-07-16 | Certain (2s)- n-[(1s)-1-cyano-2-phenylethyl]-1,4- oxazepane-2-carboxamides for treating inflammatory bowel disease |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2021530513A JP2021530513A (ja) | 2021-11-11 |
| JP2021530513A5 true JP2021530513A5 (https=) | 2022-07-21 |
Family
ID=69163563
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021502436A Pending JP2021530513A (ja) | 2018-07-17 | 2019-07-16 | 炎症性腸疾患を処置するための特定の(2s)−n−[(1s)−1−シアノ−2−フェニルエチル]−1,4−オキサゼパン−2−カルボキサミド |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20210252015A1 (https=) |
| EP (1) | EP3823628A4 (https=) |
| JP (1) | JP2021530513A (https=) |
| KR (1) | KR20210032439A (https=) |
| AU (1) | AU2019305565A1 (https=) |
| CA (1) | CA3106270A1 (https=) |
| WO (1) | WO2020018551A1 (https=) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NO2699580T3 (https=) | 2014-01-24 | 2018-02-24 | ||
| HUE070049T2 (hu) | 2018-03-01 | 2025-05-28 | Astrazeneca Ab | (2S)-{(1S)-1-ciano-2-[4-(3-metil-2-oxo-2,3-dihidro-1,3-benzoxazol-5-il)fenil]etil} -1,4-oxazepán-2-karboxamidot tartalmazó gyógyászati készítmények |
| WO2020018547A1 (en) | 2018-07-17 | 2020-01-23 | Insmed Incorporated | Certain (2s)-n-[(1s)-1-cyano-2-phenylethyl]-1,4-oxazepane-2-carboxamides for treating lupus nephritis |
| CN114106005B (zh) * | 2020-08-26 | 2025-08-01 | 西藏海思科制药有限公司 | 一种作为二肽基肽酶1抑制剂的腈衍生物及其用途 |
| WO2022140516A1 (en) * | 2020-12-22 | 2022-06-30 | Insmed Incorporated | Certain (25)-iv-[(ls')~ i-c yan0-2-phenylethyl·]- 1,4-oxazepane-2- carboxamides for treating behcet's disease |
| US20240150335A1 (en) * | 2021-02-05 | 2024-05-09 | Medshine Discovery Inc. | Fused ring derivatives containing 1,4-oxazepane |
| EP4450497A4 (en) * | 2022-01-11 | 2025-11-26 | Shanghai Yidian Pharmaceutical Tech Development Co Ltd | NITRILE PEPTIDYL COMPOUND AND ITS USES |
| EP4538271A4 (en) * | 2022-06-07 | 2025-10-08 | Reistone Biopharma Company Ltd | POLYMORPH OF BENZO[C]CHROMANE COMPOUND, ITS PREPARATION METHOD AND ITS USE |
| JP2026503035A (ja) | 2023-01-06 | 2026-01-27 | インスメッド インコーポレイテッド | 新規な可逆性dpp1阻害剤及びその用途 |
| KR20250170710A (ko) * | 2023-03-16 | 2025-12-05 | 인스메드 인코포레이티드 | 폴리사이클릭 링커를 갖는 dpp1 억제제 및 이의 용도 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20110236367A1 (en) * | 2000-09-08 | 2011-09-29 | Telenav, Inc. | Rat cathespin dipeptidyl peptidase i (dppi): crystal structure and its uses |
| EP1633702B1 (en) * | 2003-05-30 | 2008-07-02 | Prozymex A/S | Protease inhibitors |
| EP1745292A2 (en) * | 2004-04-28 | 2007-01-24 | Bayer HealthCare AG | Diagnostics and therapeutics for diseases associated with dipeptidyl-peptidase 1 (dpp1) |
| MX2011011661A (es) * | 2009-05-07 | 2011-11-18 | Astrazeneca Ab | Compuestos 1-cianoetilheterociclilcarboxamida sustituidos 750. |
| NO2699580T3 (https=) * | 2014-01-24 | 2018-02-24 | ||
| KR20240091302A (ko) * | 2016-07-29 | 2024-06-21 | 인스메드 인코포레이티드 | 기관지확장증을 치료하기 위한 특정 (2s)-n-[(1s)-1-시아노-2-페닐에틸]-1,4-옥사제판-2-카르복스아미드 |
| CA3089240A1 (en) * | 2018-02-07 | 2019-08-15 | Insmed Incorporated | Certain (2s)-n-[(1s)-1-cyano-2-phenylethyl]-1,4-oxazepane-2-carboxamides for treating anca associated vasculitides |
-
2019
- 2019-07-16 US US17/260,602 patent/US20210252015A1/en not_active Abandoned
- 2019-07-16 CA CA3106270A patent/CA3106270A1/en active Pending
- 2019-07-16 AU AU2019305565A patent/AU2019305565A1/en not_active Abandoned
- 2019-07-16 KR KR1020217004189A patent/KR20210032439A/ko not_active Ceased
- 2019-07-16 WO PCT/US2019/042026 patent/WO2020018551A1/en not_active Ceased
- 2019-07-16 JP JP2021502436A patent/JP2021530513A/ja active Pending
- 2019-07-16 EP EP19838400.0A patent/EP3823628A4/en not_active Withdrawn
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