JP2024500378A5 - - Google Patents
Info
- Publication number
- JP2024500378A5 JP2024500378A5 JP2023535992A JP2023535992A JP2024500378A5 JP 2024500378 A5 JP2024500378 A5 JP 2024500378A5 JP 2023535992 A JP2023535992 A JP 2023535992A JP 2023535992 A JP2023535992 A JP 2023535992A JP 2024500378 A5 JP2024500378 A5 JP 2024500378A5
- Authority
- JP
- Japan
- Prior art keywords
- salt
- isomer
- alkyl
- cycloalkyl
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063125654P | 2020-12-15 | 2020-12-15 | |
| US63/125,654 | 2020-12-15 | ||
| PCT/US2021/063567 WO2022132936A1 (en) | 2020-12-15 | 2021-12-15 | Multi-cyclic irak and flt3 inhibiting compounds and uses thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024500378A JP2024500378A (ja) | 2024-01-09 |
| JP2024500378A5 true JP2024500378A5 (https=) | 2024-12-24 |
Family
ID=82058056
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023535992A Pending JP2024500378A (ja) | 2020-12-15 | 2021-12-15 | 多環状ｉｒａｋ及びｆｌｔ３阻害化合物、並びにその使用 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US12534469B2 (https=) |
| EP (1) | EP4262802A4 (https=) |
| JP (1) | JP2024500378A (https=) |
| CN (1) | CN116887834A (https=) |
| AU (1) | AU2021403015A1 (https=) |
| CA (1) | CA3201690A1 (https=) |
| IL (1) | IL303709A (https=) |
| MX (1) | MX2023006937A (https=) |
| WO (1) | WO2022132936A1 (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX2024008057A (es) | 2021-12-30 | 2024-08-28 | Biomea Fusion Inc | Compuestos de pirazina como inhibidores de flt3. |
| JP2025525322A (ja) * | 2022-06-15 | 2025-08-05 | チルドレンズ ホスピタル メディカル センター | 多環式ｉｒａｋ及びｆｌｔ３阻害化合物並びにその使用 |
| AU2024264188A1 (en) * | 2023-04-28 | 2025-11-06 | Kurome Therapeutics, Inc. | Irak inhibitor free base, salts, and polymorphic forms thereof |
| WO2025029929A1 (en) * | 2023-07-31 | 2025-02-06 | Children's Hospital Medical Center | Multi-cyclic irak1 and irak4 inhibiting compounds and uses thereof |
| WO2025137567A1 (en) * | 2023-12-20 | 2025-06-26 | Children's Hospital Medical Center | Multi-cyclic irak and flt3 inhibiting compounds and uses thereof |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101324804B1 (ko) * | 2008-05-13 | 2013-11-01 | 아이알엠 엘엘씨 | 키나제 억제제로서의 질소 함유 융합 헤테로사이클 및 그의 조성물 |
| UY33304A (es) * | 2010-04-02 | 2011-10-31 | Amgen Inc | Compuestos heterocíclicos y sus usos |
| CA2806655A1 (en) | 2010-07-28 | 2012-02-02 | Bayer Intellectual Property Gmbh | Substituted imidazo[1,2-b]pyridazines |
| US10618903B2 (en) * | 2015-06-24 | 2020-04-14 | Bristol-Myers Squibb Company | Heteroaryl substituted aminopyridine compounds |
| WO2017044623A1 (en) * | 2015-09-09 | 2017-03-16 | Lau Warren C | Methods, compositions, and uses of novel fyn kinase inhibitors |
| US11542261B2 (en) * | 2016-08-17 | 2023-01-03 | Children's Hospital Medical Center | Substituted Imidazo[1,2-a]-pyridines as IRAK 1/4 and FLT3 inhibitors |
| SG11202005237SA (en) * | 2017-12-15 | 2020-07-29 | Pyramid Biosciences Inc | 5-(2-(2,5-difluorophenyl)pyrrolidin-1 -yl)-3-(1h-pyrazol-1-yl)pyrazolo[1,5-a]pyrimidine derivatives and related compounds as trk kinase inhibitors for treating cancer |
| CN110835334B (zh) * | 2018-08-16 | 2022-10-18 | 中国药科大学 | 吲哚取代唑类化合物及其用途 |
-
2021
- 2021-12-15 EP EP21907719.5A patent/EP4262802A4/en active Pending
- 2021-12-15 WO PCT/US2021/063567 patent/WO2022132936A1/en not_active Ceased
- 2021-12-15 CN CN202180093259.3A patent/CN116887834A/zh active Pending
- 2021-12-15 MX MX2023006937A patent/MX2023006937A/es unknown
- 2021-12-15 JP JP2023535992A patent/JP2024500378A/ja active Pending
- 2021-12-15 CA CA3201690A patent/CA3201690A1/en active Pending
- 2021-12-15 US US18/257,746 patent/US12534469B2/en active Active
- 2021-12-15 IL IL303709A patent/IL303709A/en unknown
- 2021-12-15 AU AU2021403015A patent/AU2021403015A1/en active Pending
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