JP2024529453A5 - - Google Patents
Info
- Publication number
- JP2024529453A5 JP2024529453A5 JP2024504973A JP2024504973A JP2024529453A5 JP 2024529453 A5 JP2024529453 A5 JP 2024529453A5 JP 2024504973 A JP2024504973 A JP 2024504973A JP 2024504973 A JP2024504973 A JP 2024504973A JP 2024529453 A5 JP2024529453 A5 JP 2024529453A5
- Authority
- JP
- Japan
- Prior art keywords
- cycloalkyl
- alkyl
- compound
- alkoxy
- formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163227834P | 2021-07-30 | 2021-07-30 | |
| US63/227,834 | 2021-07-30 | ||
| US202163289341P | 2021-12-14 | 2021-12-14 | |
| US63/289,341 | 2021-12-14 | ||
| PCT/US2022/038902 WO2023009833A1 (en) | 2021-07-30 | 2022-07-29 | Multi-cyclic irak and flt3 inhibiting compounds and uses thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024529453A JP2024529453A (ja) | 2024-08-06 |
| JP2024529453A5 true JP2024529453A5 (https=) | 2025-08-06 |
Family
ID=85088105
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024504973A Pending JP2024529453A (ja) | 2021-07-30 | 2022-07-29 | 多環式ｉｒａｋ及びｆｌｔ３阻害化合物並びにその使用 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20250154144A1 (https=) |
| EP (1) | EP4377315A4 (https=) |
| JP (1) | JP2024529453A (https=) |
| AU (1) | AU2022319843A1 (https=) |
| CA (1) | CA3226908A1 (https=) |
| IL (1) | IL310425A (https=) |
| MX (1) | MX2024001193A (https=) |
| WO (1) | WO2023009833A1 (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2024097179A1 (en) * | 2022-11-02 | 2024-05-10 | Vincerx Pharma, Inc. | Combination therapies comprising a cdk9 inhibitor for cancer |
| WO2024163764A2 (en) * | 2023-02-01 | 2024-08-08 | Children's Hospital Medical Center | Multi-cyclic irak and flt3 inhibiting compounds and uses thereof |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006038001A1 (en) * | 2004-10-06 | 2006-04-13 | Celltech R & D Limited | Aminopyrimidine derivatives as jnk inhibitors |
| JP5576370B2 (ja) * | 2008-08-06 | 2014-08-20 | ファイザー・インク | Ｃｈｋ−１阻害剤としての６置換２−ヘテロシクリルアミノピラジン化合物 |
| EP2430013B1 (en) * | 2009-05-13 | 2014-10-15 | Amgen Inc. | Heteroaryl compounds as pikk inhibitors |
| EP2338888A1 (en) * | 2009-12-24 | 2011-06-29 | Almirall, S.A. | Imidazopyridine derivatives as JAK inhibitors |
| US8673905B2 (en) * | 2011-03-17 | 2014-03-18 | Hoffmann-La Roche Inc. | Imidazo pyrazines |
| WO2015091531A1 (en) * | 2013-12-19 | 2015-06-25 | Almirall, S.A. | Imidazolopyrimidin-2-yl derivatives as jak inhibitors |
| US20170035881A1 (en) * | 2015-10-19 | 2017-02-09 | Acerta Pharma B.V. | Therapeutic Combinations of an IRAK4 Inhibitor and a BTK Inhibitor |
| DK3500571T3 (da) * | 2016-08-17 | 2021-03-08 | Childrens Hospital Med Ct | Imidazo[1,2-a]pyridinforbindelser, sammensætninger omfattende disse, fremgangsmåder til behandling af sygdomme ved hjælp af disse og fremgangsmåder til fremstilling heraf |
| US11542261B2 (en) * | 2016-08-17 | 2023-01-03 | Children's Hospital Medical Center | Substituted Imidazo[1,2-a]-pyridines as IRAK 1/4 and FLT3 inhibitors |
| US11254667B2 (en) * | 2016-08-17 | 2022-02-22 | Children's Hospital Medical Center | Substituted imidazo[1,2-A]pyridines as IRAK 1/4 and flt3 inhibitors |
| US11111245B2 (en) * | 2017-02-01 | 2021-09-07 | Aucentra Therapeutics Pty Ltd | Derivatives of N-cycloalkyl/heterocycloalkyl-4-(imidazo[1,2-a]pyridine)pyrimidin-2-amine as therapeutic agents |
| CN111269217B (zh) * | 2020-04-07 | 2021-01-08 | 苏州信诺维医药科技有限公司 | 一种嘧啶胺类化合物、其制备方法及应用 |
-
2022
- 2022-07-29 IL IL310425A patent/IL310425A/en unknown
- 2022-07-29 JP JP2024504973A patent/JP2024529453A/ja active Pending
- 2022-07-29 CA CA3226908A patent/CA3226908A1/en active Pending
- 2022-07-29 MX MX2024001193A patent/MX2024001193A/es unknown
- 2022-07-29 AU AU2022319843A patent/AU2022319843A1/en active Pending
- 2022-07-29 WO PCT/US2022/038902 patent/WO2023009833A1/en not_active Ceased
- 2022-07-29 US US18/293,109 patent/US20250154144A1/en active Pending
- 2022-07-29 EP EP22850373.6A patent/EP4377315A4/en active Pending
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