JP2024501287A5 - - Google Patents

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Publication number
JP2024501287A5
JP2024501287A5 JP2023538735A JP2023538735A JP2024501287A5 JP 2024501287 A5 JP2024501287 A5 JP 2024501287A5 JP 2023538735 A JP2023538735 A JP 2023538735A JP 2023538735 A JP2023538735 A JP 2023538735A JP 2024501287 A5 JP2024501287 A5 JP 2024501287A5
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JP
Japan
Prior art keywords
cells
particles
gene
composition
gene element
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Pending
Application number
JP2023538735A
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English (en)
Japanese (ja)
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JP2024501287A (ja
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Application filed filed Critical
Priority claimed from PCT/US2021/064887 external-priority patent/WO2022140560A1/en
Publication of JP2024501287A publication Critical patent/JP2024501287A/ja
Publication of JP2024501287A5 publication Critical patent/JP2024501287A5/ja
Pending legal-status Critical Current

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JP2023538735A 2020-12-23 2021-12-22 RNAを閉じ込めたアネロウイルス(Anellovirus)キャプシドのインビトロアセンブリ Pending JP2024501287A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202063130360P 2020-12-23 2020-12-23
US63/130,360 2020-12-23
US202163147064P 2021-02-08 2021-02-08
US63/147,064 2021-02-08
PCT/US2021/064887 WO2022140560A1 (en) 2020-12-23 2021-12-22 In vitro assembly of anellovirus capsids enclosing rna

Publications (2)

Publication Number Publication Date
JP2024501287A JP2024501287A (ja) 2024-01-11
JP2024501287A5 true JP2024501287A5 (enExample) 2025-01-07

Family

ID=82160089

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023538735A Pending JP2024501287A (ja) 2020-12-23 2021-12-22 RNAを閉じ込めたアネロウイルス(Anellovirus)キャプシドのインビトロアセンブリ

Country Status (11)

Country Link
US (2) US20220372519A1 (enExample)
EP (1) EP4267157A4 (enExample)
JP (1) JP2024501287A (enExample)
KR (1) KR20230124682A (enExample)
AU (1) AU2021409952A1 (enExample)
BR (1) BR112023012460A2 (enExample)
CA (1) CA3206361A1 (enExample)
IL (1) IL303892A (enExample)
MX (1) MX2023007643A (enExample)
TW (1) TW202235622A (enExample)
WO (1) WO2022140560A1 (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3121528A1 (en) 2018-12-12 2020-06-18 Flagship Pioneering Innovations V, Inc. Anellosomes and methods of use
TW202334423A (zh) 2021-12-15 2023-09-01 美商旗艦先鋒創新公司 表面經修飾之病毒顆粒及模組化之病毒顆粒
EP4735627A1 (en) * 2023-06-29 2026-05-06 Life Technologies Corporation Molecules resistant to nuclease digestion

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CA2264482A1 (en) 1996-09-06 1998-03-12 The Trustees Of The University Of Pennsylvania An inducible method for production of recombinant adeno-associated viruses utilizing t7 polymerase
CA2559955C (en) 2004-03-15 2016-02-16 City Of Hope Methods and compositions for the specific inhibition of gene expression by double-stranded rna
KR20110110776A (ko) 2008-12-18 2011-10-07 다이서나 파마수이티컬, 인크. 유전자 발현의 특이적 억제를 위한 연장된 다이서 기질 제제 및 방법
WO2010093788A2 (en) 2009-02-11 2010-08-19 Dicerna Pharmaceuticals, Inc. Multiplex dicer substrate rna interference molecules having joining sequences
RU2553223C2 (ru) * 2009-08-21 2015-06-10 Виргиния Тек Интеллекчуал Пропертиз, Инк. ВАКЦИНЫ НА ОСНОВЕ СВИНОГО ВИРУСА Torque teNO И СПОСОБЫ ДИАГНОСТИКИ ИНФЕКЦИЙ, ВЫЗВАННЫХ ЭТИМ ВИРУСОМ
EP2653562A1 (en) * 2012-04-20 2013-10-23 Institut Pasteur Anellovirus genome quantification as a biomarker of immune suppression
ES2728782T3 (es) 2012-05-25 2019-10-28 Univ California Métodos y composiciones para la modificación de ADN objetivo dirigida por ARN y para la modulación de la transcripción dirigida por ARN
EP4397759A3 (en) 2012-10-23 2024-10-09 Toolgen Incorporated Composition for cleaving a target dna comprising a guide rna specific for the target dna and cas protein-encoding nucleic acid or cas protein, and use thereof
PT2931898E (pt) 2012-12-12 2016-06-16 Harvard College Manipulação e otimização de sistemas, métodos e composições para manipulação de sequências com domínios funcionais
MX380562B (es) 2012-12-12 2025-03-12 Broad Inst Inc Modificaciones de sistemas, métodos y composiciones guía optimizadas para la manipulación de secuencias.
US8697359B1 (en) 2012-12-12 2014-04-15 The Broad Institute, Inc. CRISPR-Cas systems and methods for altering expression of gene products
CN105209621B (zh) 2012-12-12 2021-05-25 布罗德研究所有限公司 对用于序列操纵的改进的系统、方法和酶组合物进行的工程化和优化
KR102955556B1 (ko) 2012-12-12 2026-04-22 더 브로드 인스티튜트, 인코퍼레이티드 서열 조작을 위한 crispr-cas 성분 시스템, 방법 및 조성물
WO2014093694A1 (en) 2012-12-12 2014-06-19 The Broad Institute, Inc. Crispr-cas nickase systems, methods and compositions for sequence manipulation in eukaryotes
US9790490B2 (en) 2015-06-18 2017-10-17 The Broad Institute Inc. CRISPR enzymes and systems
CA3066750A1 (en) * 2017-06-13 2018-12-20 Flagship Pioneering Innovations V, Inc. Compositions comprising curons and uses thereof
MX2020006150A (es) 2017-12-15 2020-11-11 Flagship Pioneering Innovations Vi Llc Composiciones que comprenden polirribonucleotidos circulares y usos de las mismas.
US11166996B2 (en) * 2018-12-12 2021-11-09 Flagship Pioneering Innovations V, Inc. Anellovirus compositions and methods of use
JP2022513459A (ja) * 2018-12-12 2022-02-08 フラッグシップ パイオニアリング イノベーションズ ブイ, インコーポレイテッド タンパク質代替治療モダリティを送達するためのアネロソーム
CA3121528A1 (en) * 2018-12-12 2020-06-18 Flagship Pioneering Innovations V, Inc. Anellosomes and methods of use
KR20230036109A (ko) * 2020-06-12 2023-03-14 플래그쉽 파이어니어링 이노베이션스 브이, 인크. 바큘로바이러스 발현 시스템
KR20230041686A (ko) * 2020-06-17 2023-03-24 플래그쉽 파이어니어링 이노베이션스 브이, 인크. 아넬로바이러스를 확인 및 특징화하는 방법 및 이의 용도

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