JP2003512841A5 - - Google Patents

Info

Publication number

JP2003512841A5

JP2003512841A5 JP2001533989A JP2001533989A JP2003512841A5 JP 2003512841 A5 JP2003512841 A5 JP 2003512841A5 JP 2001533989 A JP2001533989 A JP 2001533989A JP 2001533989 A JP2001533989 A JP 2001533989A JP 2003512841 A5 JP2003512841 A5 JP 2003512841A5

Authority

JP

Japan

Prior art keywords

seq

amino acids

polypeptide

amino acid

nucleic acid

Prior art date

2000-10-20

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Pending

Links

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• 150000001413 amino acids Chemical class 0.000 description 71
• 229920001184 polypeptide Polymers 0.000 description 44
• 108090000765 processed proteins & peptides Proteins 0.000 description 44
• 102000004196 processed proteins & peptides Human genes 0.000 description 44
• 108091033319 polynucleotide Proteins 0.000 description 32
• 102000040430 polynucleotide Human genes 0.000 description 32
• 239000002157 polynucleotide Substances 0.000 description 32
• 102000039446 nucleic acids Human genes 0.000 description 26
• 108020004707 nucleic acids Proteins 0.000 description 26
• 150000007523 nucleic acids Chemical class 0.000 description 26
• FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 description 23
• 239000000203 mixture Substances 0.000 description 21
• 238000000034 method Methods 0.000 description 18
• 125000003275 alpha amino acid group Chemical group 0.000 description 15
• 210000004027 cell Anatomy 0.000 description 10
• 201000010099 disease Diseases 0.000 description 8
• 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 8
• -1 SEQ ID NO: 2 amino acids Chemical class 0.000 description 7
• 239000002773 nucleotide Substances 0.000 description 7
• 125000003729 nucleotide group Chemical group 0.000 description 7
• 108091026890 Coding region Proteins 0.000 description 6
• 239000012634 fragment Substances 0.000 description 6
• GOJUJUVQIVIZAV-UHFFFAOYSA-N 2-amino-4,6-dichloropyrimidine-5-carbaldehyde Chemical group NC1=NC(Cl)=C(C=O)C(Cl)=N1 GOJUJUVQIVIZAV-UHFFFAOYSA-N 0.000 description 4
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• 230000035764 nutrition Effects 0.000 description 2
• 235000016709 nutrition Nutrition 0.000 description 2
• 125000002924 primary amino group Chemical group [H]N([H])* 0.000 description 2
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• 206010010356 Congenital anomaly Diseases 0.000 description 1
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• 108091008794 FGF receptors Proteins 0.000 description 1
• 102000044168 Fibroblast Growth Factor Receptor Human genes 0.000 description 1
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• 208000027530 Meniere disease Diseases 0.000 description 1
• 208000004843 Pendred Syndrome Diseases 0.000 description 1
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