|
US3891696A
(en)
|
1973-11-02 |
1975-06-24 |
Interx Research Corp |
Novel, transient pro-drug forms of l-dopa
|
|
DE2513940A1
(de)
|
1975-03-29 |
1976-10-14 |
Merck Patent Gmbh |
Pharmazeutische zubereitung
|
|
US4077407A
(en)
|
1975-11-24 |
1978-03-07 |
Alza Corporation |
Osmotic devices having composite walls
|
|
FR2470599A1
(fr)
|
1979-12-07 |
1981-06-12 |
Panoz Donald |
Perfectionnements apportes aux procedes de preparation de formes galeniques a action retard et a liberation programmee et formes galeniques de medicaments ainsi obtenus
|
|
DE3000979A1
(de)
|
1980-01-12 |
1981-07-23 |
Dr. Karl Thomae Gmbh, 7950 Biberach |
Neue dipyridamol-retardformen und verfahren zu ihrer herstellung
|
|
DE3124090A1
(de)
|
1981-06-19 |
1983-01-05 |
Dr. Karl Thomae Gmbh, 7950 Biberach |
Neue orale dipyridamolformen
|
|
DE3126703A1
(de)
|
1981-07-07 |
1983-01-27 |
Dr. Karl Thomae Gmbh, 7950 Biberach |
Bromhexin-retardform und verfahren zu ihrer herstellung
|
|
US4424235A
(en)
|
1981-09-14 |
1984-01-03 |
Hoffmann-La Roche Inc. |
Hydrodynamically balanced controlled release compositions containing L-dopa and a decarboxylase inhibitor
|
|
US5188840A
(en)
|
1985-09-26 |
1993-02-23 |
Chugai Seiyaku Kabushiki Kaisha |
Slow-release pharmaceutical agent
|
|
IT1188212B
(it)
|
1985-12-20 |
1988-01-07 |
Paolo Colombo |
Sistema per il rilascio a velocita' controllata di sostanze attive
|
|
US4849227A
(en)
|
1986-03-21 |
1989-07-18 |
Eurasiam Laboratories, Inc. |
Pharmaceutical compositions
|
|
DE252290T1
(de)
|
1986-06-10 |
1988-06-09 |
Chiesi Farmaceutici S.P.A., Parma |
Levodopa-methyl-ester enthaltende pharmazeutische zusammensetzungen, ihre herstellung und therapeutische verwendungen.
|
|
NZ220599A
(en)
|
1986-06-16 |
1990-10-26 |
Merck & Co Inc |
Controlled release oral dosage formulation of carbidopa and levodopa
|
|
US4832957A
(en)
|
1987-12-11 |
1989-05-23 |
Merck & Co., Inc. |
Controlled release combination of carbidopa/levodopa
|
|
ZA889189B
(en)
|
1986-06-16 |
1989-08-30 |
Merck & Co Inc |
Controlled release combination of carbidopa/levodopa
|
|
US5283352A
(en)
|
1986-11-28 |
1994-02-01 |
Orion-Yhtyma Oy |
Pharmacologically active compounds, methods for the preparation thereof and compositions containing the same
|
|
US4855326A
(en)
|
1987-04-20 |
1989-08-08 |
Fuisz Pharmaceutical Ltd. |
Rapidly dissoluble medicinal dosage unit and method of manufacture
|
|
EP0313845A1
(en)
|
1987-09-29 |
1989-05-03 |
Warner-Lambert Company |
Stabilization of enteric coated dosage form
|
|
US4938968A
(en)
|
1988-07-26 |
1990-07-03 |
Norjec Development Associates, Inc. |
Controlled release indomethacin
|
|
IT1229856B
(it)
|
1989-04-20 |
1991-09-13 |
Recordati Chem Pharm |
Compresse a rilascio controllato contenenti flavossato.
|
|
GB2238047B
(en)
|
1989-11-03 |
1993-02-10 |
Orion Yhtymae Oy |
Stable polymorphic form of (e)-n,n-diethyl-2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)acrylamide and the process for its preparation
|
|
IE66933B1
(en)
|
1990-01-15 |
1996-02-07 |
Elan Corp Plc |
Controlled absorption naproxen formulation for once-daily administration
|
|
DE4101873C2
(de)
|
1991-01-23 |
1993-12-09 |
Isis Pharma Gmbh |
Peroral applizierbare Arzneiform zur Behandlung zentraler Dopaminmangelzustände
|
|
US5624960A
(en)
|
1991-01-23 |
1997-04-29 |
Isis Pharma Gmbh |
Orally administrable drugs for the treatment of central dopamine deficiency conditions
|
|
IT1255522B
(it)
|
1992-09-24 |
1995-11-09 |
Ubaldo Conte |
Compressa per impiego terapeutico atta a cedere una o piu' sostanze attive con differenti velocita'
|
|
GB9309749D0
(en)
|
1993-05-12 |
1993-06-23 |
Boots Co Plc |
Therapeutic agents
|
|
IT1264517B1
(it)
|
1993-05-31 |
1996-09-24 |
Ekita Investments Nv |
Compressa farmaceutica atta al rilascio in tempi successivi dei principi attivi in essa veicolati
|
|
IT1264696B1
(it)
|
1993-07-09 |
1996-10-04 |
Applied Pharma Res |
Forme farmaceutiche destinate alla somministrazione orale in grado di rilasciare sostanze attive a velocita' controllata e differenziata
|
|
IT1266565B1
(it)
|
1993-07-22 |
1997-01-09 |
Ct Lab Farm Srl |
Composizioni farmaceutiche a rilascio controllato a base di uno o piu' sali farmaceuticamente accettabili dell'acido gamma-idrossi-butirrico.
|
|
JPH09500645A
(ja)
|
1993-07-22 |
1997-01-21 |
ワーナー−ランバート・コンパニー |
制御放出タクリン薬物送達システムおよびその製造方法
|
|
US6183778B1
(en)
|
1993-09-21 |
2001-02-06 |
Jagotec Ag |
Pharmaceutical tablet capable of liberating one or more drugs at different release rates
|
|
SG80553A1
(en)
|
1995-07-20 |
2001-05-22 |
Tanabe Seiyaku Co |
Pharmaceutical preparation in form of coated capsule releasable at lower part of digestive tract
|
|
US5840756A
(en)
|
1995-07-21 |
1998-11-24 |
Teva Pharmaceutical Industries Ltd. |
Pharmaceutical composition of L-DOPA ester
|
|
AUPN605795A0
(en)
|
1995-10-19 |
1995-11-09 |
F.H. Faulding & Co. Limited |
Analgesic pharmaceutical composition
|
|
IT1282576B1
(it)
|
1996-02-06 |
1998-03-31 |
Jagotec Ag |
Compressa farmaceutica atta a cedere la sostanza attiva in tempi successivi e predeterminabili
|
|
IT1282650B1
(it)
|
1996-02-19 |
1998-03-31 |
Jagotec Ag |
Compressa farmaceutica,caratterizzata da elevato aumento di volume a contatto con liquidi biologici
|
|
US5773031A
(en)
|
1996-02-27 |
1998-06-30 |
L. Perrigo Company |
Acetaminophen sustained-release formulation
|
|
IT1289160B1
(it)
|
1997-01-08 |
1998-09-29 |
Jagotec Ag |
Compressa farmaceutica completamente rivestita per il rilascio controllato di principi attivi che presentano problemi di
|
|
US6756056B2
(en)
|
1997-04-08 |
2004-06-29 |
Alan A. Rubin |
Treatment of Parkinson's disease and related disorders by novel formulations of the combination carbidopa-levodopa
|
|
US6024981A
(en)
|
1997-04-16 |
2000-02-15 |
Cima Labs Inc. |
Rapidly dissolving robust dosage form
|
|
IT1293764B1
(it)
|
1997-07-23 |
1999-03-10 |
Chiesi Farma Spa |
Composizioni farmaceutiche sotto forma di compresse effervescenti contenenti un principio attivo instabile in presenza di acqua
|
|
IT1295271B1
(it)
|
1997-10-03 |
1999-05-04 |
Chiesi Farma Spa |
Monolita contenente uno o piu'farmaci costituito da tre strati a meccanismo di rilascio differenziato
|
|
US6372254B1
(en)
|
1998-04-02 |
2002-04-16 |
Impax Pharmaceuticals Inc. |
Press coated, pulsatile drug delivery system suitable for oral administration
|
|
US5945424A
(en)
|
1998-07-31 |
1999-08-31 |
G & H Associates, Inc. |
Treatment of periodic limb movement syndrome
|
|
WO2000015197A1
(en)
|
1998-09-14 |
2000-03-23 |
Rubin Alan A |
Improvement in treatment of parkinson's disease and related disorders by novel formulations of the combination carbidopa-levodopa
|
|
US6602521B1
(en)
|
1998-09-29 |
2003-08-05 |
Impax Pharmaceuticals, Inc. |
Multiplex drug delivery system suitable for oral administration
|
|
MXPA01004381A
(es)
|
1998-11-02 |
2005-09-08 |
Elan Corp Plc |
Composicion de multiparticulado de liberacion modificada.
|
|
NZ512027A
(en)
|
1998-11-10 |
2004-04-30 |
Teva Pharma |
Dispersible compositions containing L-dopa ethyl ester
|
|
PT1140012E
(pt)
|
1998-12-17 |
2004-05-31 |
Alza Corp |
Conversao de capsulas de gelatina cheias com liquido em sistemas de libertacao controlada por camadas multiplas
|
|
FI109453B
(fi)
|
1999-06-30 |
2002-08-15 |
Orion Yhtymae Oyj |
Farmaseuttinen koostumus
|
|
HUP0203028A3
(en)
|
1999-11-11 |
2005-07-28 |
Pharmacia Ab |
Pharmaceutical formulation containing tolterodine and its use
|
|
US6627223B2
(en)
|
2000-02-11 |
2003-09-30 |
Eurand Pharmaceuticals Ltd. |
Timed pulsatile drug delivery systems
|
|
US6372252B1
(en)
|
2000-04-28 |
2002-04-16 |
Adams Laboratories, Inc. |
Guaifenesin sustained release formulation and tablets
|
|
JP2004501190A
(ja)
|
2000-06-23 |
2004-01-15 |
テバ ファーマシューティカル インダストリーズ リミティド |
治療薬の胃部保留および制御された放出のための急速膨張する組成物とその組成物を含む剤形
|
|
US6733781B2
(en)
|
2000-12-06 |
2004-05-11 |
Wyeth |
Fast dissolving tablet
|
|
US6531153B2
(en)
|
2001-05-29 |
2003-03-11 |
Drugtech Corporation |
Composition with sustained release of levodopa and carbidopa
|
|
US20040028613A1
(en)
|
2001-06-25 |
2004-02-12 |
Nastech Pharmaceutical Company Inc |
Dopamine agonist formulations for enhanced central nervous system delivery
|
|
IL159812A0
(en)
|
2001-07-12 |
2004-06-20 |
Teva Pharma |
Dual release formulation comprising levodopa ethyl ester and a decarboxylase inhibitor in immediate release layer with levodopa ethyl ester in a controlled release core
|
|
IL159813A0
(en)
|
2001-07-12 |
2004-06-20 |
Teva Pharma |
Dual release formulation comprising levodopa ethyl ester and a decarboxylase inhibitor in immediate release layer with levodopa ethyl ester and a decarboxylase inhibitor in a controlled release core
|
|
US6723348B2
(en)
|
2001-11-16 |
2004-04-20 |
Ethypharm |
Orodispersible tablets containing fexofenadine
|
|
US6811794B2
(en)
|
2001-12-20 |
2004-11-02 |
Shire Laboratories, Inc. |
Sustained release pharmaceutical dosage forms with minimized pH dependent dissolution profiles
|
|
US20060013875A1
(en)
|
2002-05-29 |
2006-01-19 |
Impax Laboratories, Inc. |
Combination immediate release controlled release levodopa/carbidopa dosage forms
|
|
US20030224045A1
(en)
|
2002-05-29 |
2003-12-04 |
Chien-Hsuan Han |
Combination immediate release sustained release levodopa/carbidopa dosage forms
|
|
US7094427B2
(en)
|
2002-05-29 |
2006-08-22 |
Impax Laboratories, Inc. |
Combination immediate release controlled release levodopa/carbidopa dosage forms
|
|
US20050147670A1
(en)
|
2002-05-29 |
2005-07-07 |
Impax Laboratories Inc. |
Oral disintegrating dosage forms
|
|
US20040166159A1
(en)
|
2002-05-29 |
2004-08-26 |
Chien-Hsuan Han |
Pharmaceutical dosage forms having immediate and controlled release properties that contain an aromatic amino acid decarboxylase inhibitor and levodopa
|
|
EP1589951B1
(en)
|
2003-01-03 |
2017-08-09 |
Supernus Pharmaceuticals, Inc. |
Use of a mixture of two or more enteric materials to regulate drug release via membrane or matrix for systemic therapeutics
|
|
ES2665464T3
(es)
|
2003-03-28 |
2018-04-25 |
Sigmoid Pharma Limited |
Forma de dosificación oral sólida que contiene microcápsulas sin costuras
|
|
US8815950B2
(en)
|
2003-08-29 |
2014-08-26 |
Janssen Biotech, Inc. |
Pharmaceutical compositions and method of using levodopa and carbidopa
|
|
DE602004031134D1
(de)
|
2003-08-29 |
2011-03-03 |
Transform Pharmaceuticals Inc |
Pharmazeutische zusammensetzungen und verfahren zur verwendung von levodopa und carbidopa
|
|
US8007827B2
(en)
|
2004-04-02 |
2011-08-30 |
Impax Laboratories, Inc. |
Pharmaceutical dosage forms having immediate release and/or controlled release properties
|
|
WO2005099678A1
(en)
|
2004-04-06 |
2005-10-27 |
Transform Pharmaceuticals, Inc. |
Pharmaceutical compositions and method of using levodopa and carbidopa
|
|
JP2008516893A
(ja)
|
2004-08-27 |
2008-05-22 |
スフェリックス，インク． |
多層錠剤および生体接着性剤形
|
|
US20060045865A1
(en)
|
2004-08-27 |
2006-03-02 |
Spherics, Inc. |
Controlled regional oral delivery
|
|
WO2006133349A2
(en)
|
2005-06-08 |
2006-12-14 |
Alpharma, Inc. |
Orally disintegrable sleep aid formulations
|
|
CA2613631A1
(en)
|
2005-06-23 |
2007-01-04 |
Spherics, Inc. |
Improved dosage forms for movement disorder treatment
|
|
WO2007002518A1
(en)
|
2005-06-23 |
2007-01-04 |
Spherics, Inc. |
Delayed release or extended-delayed release dosage forms of pramipexole
|
|
AR055106A1
(es)
|
2005-08-05 |
2007-08-08 |
Osmotica Pharmaceutical Argent |
Composicion farmaceutica solida de liberacion extendida que contiene carbidopa y levodopa
|
|
EP1919460A2
(en)
|
2005-08-22 |
2008-05-14 |
Novartis AG |
Pharmaceutical compositions comprising a ph-dependent drug, a ph modifier and a retarding agent
|
|
FR2891459B1
(fr)
|
2005-09-30 |
2007-12-28 |
Flamel Technologies Sa |
Microparticules a liberation modifiee d'au moins un principe actif et forme galenique orale en comprenant
|
|
WO2007072911A1
(ja)
|
2005-12-22 |
2007-06-28 |
Asubio Pharma Co., Ltd. |
塩酸サプロプテリンの生体内吸収性を向上させた製剤
|
|
KR20140088230A
(ko)
|
2006-01-27 |
2014-07-09 |
앱탈리스 파마테크, 인코포레이티드 |
약 염기성 약물과 유기산을 포함하는 약물 전달 시스템
|
|
CN101410094B
(zh)
|
2006-01-27 |
2013-04-17 |
阿普塔利斯制药股份有限公司 |
包含弱碱性选择性5-羟色胺5-ht3阻断剂和有机酸的药物递送系统
|
|
US20080131492A1
(en)
|
2006-06-23 |
2008-06-05 |
Spherics, Inc. |
Dosage forms for movement disorder treatment
|
|
US8637080B2
(en)
|
2007-06-28 |
2014-01-28 |
Osmotica Kereskedelmi és Szolgáltató, KFT |
Rupturing controlled release device comprising a subcoat
|
|
CN101910113A
(zh)
|
2007-12-28 |
2010-12-08 |
怡百克制药公司 |
左旋多巴控释制剂及其用途
|
|
PL2432454T3
(pl)
*
|
2009-05-19 |
2017-10-31 |
Neuroderm Ltd |
Kompozycje do ciągłego podawania inhibitorów dopa-dekarboksylazy
|
|
US20100331244A1
(en)
|
2009-06-01 |
2010-12-30 |
The University Of Tokyo |
Pharmaceutical composition, food or drink, and methods related thereto
|
|
WO2011056240A2
(en)
|
2009-11-09 |
2011-05-12 |
Xenoport, Inc. |
Pharmaceutical compositions and oral dosage forms of a levodopa prodrug and methods of use
|
|
WO2012059815A1
(en)
*
|
2010-11-01 |
2012-05-10 |
Intec Pharma Ltd. |
Accordion pill comprising levodopa for an improved treatment of parkinson's disease symptoms
|
|
EP2694538B1
(en)
|
2011-04-05 |
2016-09-14 |
Annexin Pharmaceuticals AB |
Therapeutic and prophylactic methods, uses and compositions comprising anexin a5
|
|
EP2508174A1
(en)
|
2011-04-06 |
2012-10-10 |
Ljiljana Sovic Brkicic |
Pharmaceutical composition
|
|
US20130195973A1
(en)
|
2012-01-30 |
2013-08-01 |
Ranbaxy Laboratories Limited |
Extended release pharmaceutical dosage forms of carbidopa and levodopa and process of preparation thereof
|
|
US10987313B2
(en)
|
2013-10-07 |
2021-04-27 |
Impax Laboratories, Llc |
Muco-adhesive, controlled release formulations of levodopa and/or esters of levodopa and uses thereof
|
|
CN105658211A
(zh)
|
2013-10-07 |
2016-06-08 |
怡百克制药公司 |
左旋多巴和/或左旋多巴的酯的粘膜粘附性、控制释放调配物和其用途
|
|
RU2017120184A
(ru)
*
|
2014-11-28 |
2018-12-28 |
БИАЛ - ПОРТЕЛА ЭНД Ка, С.А. |
Лекарства для замедления течения болезни паркинсона
|
|
AU2017297718B2
(en)
*
|
2016-07-11 |
2023-06-08 |
Contera Pharma A/S |
Pulsatile drug delivery system for treating morning akinesia
|
|
CN108024293B
(zh)
|
2016-11-04 |
2021-07-09 |
中兴通讯股份有限公司 |
一种传输带宽的配置方法及发射节点
|