JP2024164167A5 - - Google Patents
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- Publication number
- JP2024164167A5 JP2024164167A5 JP2024142687A JP2024142687A JP2024164167A5 JP 2024164167 A5 JP2024164167 A5 JP 2024164167A5 JP 2024142687 A JP2024142687 A JP 2024142687A JP 2024142687 A JP2024142687 A JP 2024142687A JP 2024164167 A5 JP2024164167 A5 JP 2024164167A5
- Authority
- JP
- Japan
- Prior art keywords
- subject
- sulfonylurea
- pharmaceutical composition
- therapeutic dose
- administered
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000008194 pharmaceutical composition Substances 0.000 claims 19
- 229940100389 Sulfonylurea Drugs 0.000 claims 18
- YROXIXLRRCOBKF-UHFFFAOYSA-N sulfonylurea Chemical class OC(=N)N=S(=O)=O YROXIXLRRCOBKF-UHFFFAOYSA-N 0.000 claims 18
- 238000011287 therapeutic dose Methods 0.000 claims 16
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims 9
- 238000001802 infusion Methods 0.000 claims 7
- 206010061216 Infarction Diseases 0.000 claims 6
- 230000002490 cerebral effect Effects 0.000 claims 6
- 230000007574 infarction Effects 0.000 claims 6
- 239000008280 blood Substances 0.000 claims 5
- 210000004369 blood Anatomy 0.000 claims 5
- 239000008103 glucose Substances 0.000 claims 5
- 238000001514 detection method Methods 0.000 claims 4
- 230000006866 deterioration Effects 0.000 claims 4
- 230000000926 neurological effect Effects 0.000 claims 4
- 230000000991 decompressive effect Effects 0.000 claims 3
- 230000000977 initiatory effect Effects 0.000 claims 3
- 206010048962 Brain oedema Diseases 0.000 claims 1
- 206010051290 Central nervous system lesion Diseases 0.000 claims 1
- 210000004556 brain Anatomy 0.000 claims 1
- 208000006752 brain edema Diseases 0.000 claims 1
- 238000007428 craniotomy Methods 0.000 claims 1
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562238461P | 2015-10-07 | 2015-10-07 | |
| US62/238,461 | 2015-10-07 | ||
| JP2021022562A JP2021073317A (ja) | 2015-10-07 | 2021-02-16 | Ｃｎｓ浮腫に関連する損傷または状態を処置する方法 |
| JP2023020327A JP7592768B2 (ja) | 2015-10-07 | 2023-02-13 | Ｃｎｓ浮腫に関連する損傷または状態を処置する方法 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023020327A Division JP7592768B2 (ja) | 2015-10-07 | 2023-02-13 | Ｃｎｓ浮腫に関連する損傷または状態を処置する方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024164167A JP2024164167A (ja) | 2024-11-26 |
| JP2024164167A5 true JP2024164167A5 (enExample) | 2025-03-24 |
Family
ID=58488580
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018517841A Active JP7349786B2 (ja) | 2015-10-07 | 2016-10-07 | Ｃｎｓ浮腫に関連する損傷または状態を処置する方法 |
| JP2021022562A Withdrawn JP2021073317A (ja) | 2015-10-07 | 2021-02-16 | Ｃｎｓ浮腫に関連する損傷または状態を処置する方法 |
| JP2023020327A Active JP7592768B2 (ja) | 2015-10-07 | 2023-02-13 | Ｃｎｓ浮腫に関連する損傷または状態を処置する方法 |
| JP2024142687A Pending JP2024164167A (ja) | 2015-10-07 | 2024-08-23 | Ｃｎｓ浮腫に関連する損傷または状態を処置する方法 |
Family Applications Before (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018517841A Active JP7349786B2 (ja) | 2015-10-07 | 2016-10-07 | Ｃｎｓ浮腫に関連する損傷または状態を処置する方法 |
| JP2021022562A Withdrawn JP2021073317A (ja) | 2015-10-07 | 2021-02-16 | Ｃｎｓ浮腫に関連する損傷または状態を処置する方法 |
| JP2023020327A Active JP7592768B2 (ja) | 2015-10-07 | 2023-02-13 | Ｃｎｓ浮腫に関連する損傷または状態を処置する方法 |
Country Status (15)
| Country | Link |
|---|---|
| US (4) | US20180280325A1 (enExample) |
| EP (1) | EP3359162B1 (enExample) |
| JP (4) | JP7349786B2 (enExample) |
| KR (2) | KR20240105519A (enExample) |
| CN (2) | CN108348534A (enExample) |
| AU (3) | AU2016335767B2 (enExample) |
| BR (1) | BR112018006925A2 (enExample) |
| CA (1) | CA3001321A1 (enExample) |
| EA (1) | EA201890893A1 (enExample) |
| ES (1) | ES2940669T3 (enExample) |
| HK (1) | HK1257542A1 (enExample) |
| IL (1) | IL258509B2 (enExample) |
| MA (1) | MA45574A (enExample) |
| MX (1) | MX392466B (enExample) |
| WO (1) | WO2017062765A1 (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR112014027983B1 (pt) | 2012-05-08 | 2022-05-24 | Aeromics, Inc | Uso de inibidores de aquaporina seletivos |
| WO2015069961A1 (en) | 2013-11-06 | 2015-05-14 | Aeromics, Llc | Novel prodrug salts |
| KR20240105519A (ko) * | 2015-10-07 | 2024-07-05 | 레메디 파마슈티칼즈, 인크. | Cns 부종과 관련한 손상 또는 병태의 치료 방법 |
| WO2020041905A1 (en) * | 2018-08-31 | 2020-03-05 | The University Of British Columbia | Methods for identifying compounds suitable for treatment of central nervous system trauma and uses of those compounds |
| CN113874002A (zh) * | 2019-05-02 | 2021-12-31 | 生物切萨皮克有限责任公司 | 治疗患有中枢神经系统挫伤的受试者的方法 |
| TW202214561A (zh) * | 2020-07-17 | 2022-04-16 | 大陸商上海森輝醫藥有限公司 | 磺醯脲類衍生物及其醫藥用途 |
| US12251388B1 (en) | 2024-05-09 | 2025-03-18 | Remedy Pharmaceuticals, Inc. | Methods of treating ischemic stroke at risk for cerebral or cerebellar edema |
| WO2025212189A1 (en) * | 2024-04-05 | 2025-10-09 | Remedy Pharmaceuticals, Inc. | Methods of treating ischemic stroke at risk for cerebral or cerebellar edema using a sur1-trpm4 channel inhibitor |
| WO2025212155A1 (en) * | 2024-04-05 | 2025-10-09 | Remedy Pharmaceuticals, Inc. | Methods of treating ischemic stroke with large vessel occlusion using a sur1-trpm4 channel inhibitor |
| US12251389B1 (en) | 2024-04-22 | 2025-03-18 | Remedy Pharmaceuticals, Inc. | Methods of treating ischemic stroke at risk for cerebral or cerebellar edema |
| WO2025212154A1 (en) * | 2024-04-05 | 2025-10-09 | Remedy Pharmaceuticals, Inc. | Methods of treating ischemic stroke at risk for cerebral or cerebellar edema |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5856360A (en) | 1996-05-03 | 1999-01-05 | Children's Hospital Medical Center | Pharmaceutical method for the treatment of severe blood loss and for the inhibition or treatment of hemorrhagic shock |
| DK2438913T3 (da) * | 2002-03-20 | 2020-06-22 | Univ Maryland | Ikke-selektiv kationkanal i neurale celler og forbindelser, der blokerer kanalen, til anvendelse i behandling af opsvulmning af hjernen |
| US8980952B2 (en) * | 2002-03-20 | 2015-03-17 | University Of Maryland, Baltimore | Methods for treating brain swelling with a compound that blocks a non-selective cation channel |
| US20050246000A1 (en) * | 2004-05-03 | 2005-11-03 | Seacoast Technologies, Inc. | Cooled craniectomy |
| EP2167107B1 (en) | 2007-06-22 | 2016-12-14 | University of Maryland, Baltimore | Inhibitors of ncca-atp channels for therapy |
| WO2009073711A1 (en) * | 2007-12-04 | 2009-06-11 | Remedy Pharmaceuticals, Inc. | Improved formulations and methods for lyophilization and lyophilates provided thereby |
| JP6188021B2 (ja) * | 2010-07-19 | 2017-08-30 | バイオジェン チェサピーク エルエルシー | グリブリドおよび他の薬剤の静脈内投与方法 |
| KR20240105519A (ko) * | 2015-10-07 | 2024-07-05 | 레메디 파마슈티칼즈, 인크. | Cns 부종과 관련한 손상 또는 병태의 치료 방법 |
-
2016
- 2016-10-07 KR KR1020247021781A patent/KR20240105519A/ko not_active Ceased
- 2016-10-07 HK HK18116503.6A patent/HK1257542A1/zh unknown
- 2016-10-07 CN CN201680066630.6A patent/CN108348534A/zh active Pending
- 2016-10-07 KR KR1020187012950A patent/KR102681027B1/ko active Active
- 2016-10-07 BR BR112018006925A patent/BR112018006925A2/pt not_active Application Discontinuation
- 2016-10-07 AU AU2016335767A patent/AU2016335767B2/en active Active
- 2016-10-07 US US15/763,932 patent/US20180280325A1/en not_active Abandoned
- 2016-10-07 ES ES16854422T patent/ES2940669T3/es active Active
- 2016-10-07 EP EP16854422.9A patent/EP3359162B1/en active Active
- 2016-10-07 MA MA045574A patent/MA45574A/fr unknown
- 2016-10-07 EA EA201890893A patent/EA201890893A1/ru unknown
- 2016-10-07 IL IL258509A patent/IL258509B2/en unknown
- 2016-10-07 JP JP2018517841A patent/JP7349786B2/ja active Active
- 2016-10-07 WO PCT/US2016/055988 patent/WO2017062765A1/en not_active Ceased
- 2016-10-07 CA CA3001321A patent/CA3001321A1/en active Pending
- 2016-10-07 CN CN202211412393.8A patent/CN115737816A/zh active Pending
- 2016-10-07 MX MX2018004286A patent/MX392466B/es unknown
-
2021
- 2021-02-16 JP JP2021022562A patent/JP2021073317A/ja not_active Withdrawn
- 2021-09-29 US US17/488,591 patent/US11951085B2/en active Active
-
2022
- 2022-11-28 AU AU2022279369A patent/AU2022279369B2/en active Active
-
2023
- 2023-02-13 JP JP2023020327A patent/JP7592768B2/ja active Active
-
2024
- 2024-03-04 US US18/595,205 patent/US20240216309A1/en active Pending
- 2024-08-23 JP JP2024142687A patent/JP2024164167A/ja active Pending
- 2024-09-30 US US18/902,504 patent/US20250017880A1/en active Pending
-
2025
- 2025-04-14 AU AU2025202620A patent/AU2025202620A1/en active Pending
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