JP2024119984A5 - - Google Patents

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Publication number
JP2024119984A5
JP2024119984A5 JP2024096802A JP2024096802A JP2024119984A5 JP 2024119984 A5 JP2024119984 A5 JP 2024119984A5 JP 2024096802 A JP2024096802 A JP 2024096802A JP 2024096802 A JP2024096802 A JP 2024096802A JP 2024119984 A5 JP2024119984 A5 JP 2024119984A5
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JP
Japan
Prior art keywords
amino acid
seq
pharmaceutical according
represented
acid sequence
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Pending
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JP2024096802A
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English (en)
Japanese (ja)
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JP2024119984A (ja
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Priority claimed from PCT/JP2019/051594 external-priority patent/WO2020138487A1/ja
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Publication of JP2024119984A publication Critical patent/JP2024119984A/ja
Publication of JP2024119984A5 publication Critical patent/JP2024119984A5/ja
Pending legal-status Critical Current

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JP2024096802A 2018-12-28 2024-06-14 TfRに結合するバイスペシフィック抗体 Pending JP2024119984A (ja)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP2018248334 2018-12-28
JP2018248334 2018-12-28
PCT/JP2019/051594 WO2020138487A1 (ja) 2018-12-28 2019-12-27 TfRに結合するバイスペシフィック抗体
JP2020562545A JP7506607B2 (ja) 2018-12-28 2019-12-27 TfRに結合するバイスペシフィック抗体

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2020562545A Division JP7506607B2 (ja) 2018-12-28 2019-12-27 TfRに結合するバイスペシフィック抗体

Publications (2)

Publication Number Publication Date
JP2024119984A JP2024119984A (ja) 2024-09-03
JP2024119984A5 true JP2024119984A5 (enExample) 2024-09-25

Family

ID=71125764

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2020562545A Active JP7506607B2 (ja) 2018-12-28 2019-12-27 TfRに結合するバイスペシフィック抗体
JP2024096802A Pending JP2024119984A (ja) 2018-12-28 2024-06-14 TfRに結合するバイスペシフィック抗体

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP2020562545A Active JP7506607B2 (ja) 2018-12-28 2019-12-27 TfRに結合するバイスペシフィック抗体

Country Status (13)

Country Link
US (2) US12258413B2 (enExample)
EP (1) EP3903816A4 (enExample)
JP (2) JP7506607B2 (enExample)
KR (1) KR20210108961A (enExample)
CN (1) CN113226371B (enExample)
AU (1) AU2019413278B2 (enExample)
BR (1) BR112021012569A2 (enExample)
CA (1) CA3125316A1 (enExample)
MX (1) MX2021007797A (enExample)
MY (1) MY210422A (enExample)
SG (1) SG11202106990PA (enExample)
TW (2) TWI873112B (enExample)
WO (1) WO2020138487A1 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113563473A (zh) * 2020-04-29 2021-10-29 三生国健药业(上海)股份有限公司 四价双特异性抗体、其制备方法和用途
CA3237844A1 (en) 2021-11-15 2023-05-19 Systimmune, Inc. Bispecific antibody-camptothecin drug conjugate and pharmaceutical use thereof
EP4688846A1 (en) * 2023-03-24 2026-02-11 BioArctic AB Antibody binding to the protease-like domain of the human transferrin receptor htfr1
KR20260044219A (ko) 2023-07-21 2026-04-01 매로우 테라퓨틱스, 인크. 조혈 세포 표적화 접합체 및 관련 방법
TW202517685A (zh) * 2023-10-26 2025-05-01 美商百健Ma公司 抗運鐵蛋白受體抗體及其用途

Family Cites Families (59)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US570561A (en) 1896-11-03 S peters co
US2808035A (en) 1953-04-23 1957-10-01 Riley Stoker Corp Burning wet materials
JPS5623587A (en) 1979-08-03 1981-03-05 Mitsuwa Seiki Co Ltd Vane type compressor
JPS58110600A (ja) 1981-12-25 1983-07-01 Kyowa Hakko Kogyo Co Ltd ヒトβ型インタ−フエロン遺伝子を含む組みかえ体プラスミド
WO1985003934A1 (fr) 1984-03-06 1985-09-12 Takeda Chemical Industries, Ltd. Proteine modifiee chimiquement et son procede de preparation
JPS60221091A (ja) 1983-12-21 1985-11-05 Kyowa Hakko Kogyo Co Ltd 新規プロモ−タ−
US5168062A (en) 1985-01-30 1992-12-01 University Of Iowa Research Foundation Transfer vectors and microorganisms containing human cytomegalovirus immediate-early promoter-regulatory DNA sequence
JP2564268B2 (ja) 1985-08-28 1996-12-18 協和醗酵工業株式会社 融合抗原ポリペプチド
ZA872705B (en) 1986-04-22 1987-10-05 Immunex Corporation Human g-csf protein expression
JP2958019B2 (ja) 1988-05-06 1999-10-06 住友製薬株式会社 ポリエチレングリコール誘導体、修飾ペプチドおよびその製造方法
JP2928287B2 (ja) 1988-09-29 1999-08-03 協和醗酵工業株式会社 新規ポリペプチド
JPH02257891A (ja) 1989-03-31 1990-10-18 Kyowa Hakko Kogyo Co Ltd 組換え動物細胞による蛋白質の製造
JPH0322979A (ja) 1989-06-19 1991-01-31 Kyowa Hakko Kogyo Co Ltd 新規プラスミノーゲン活性化因子
JP3131322B2 (ja) 1991-12-17 2001-01-31 協和醗酵工業株式会社 新規α2→3シアリルトランスフェラーゼ
US6042828A (en) 1992-09-07 2000-03-28 Kyowa Hakko Kogyo Co., Ltd. Humanized antibodies to ganglioside GM2
EP0643132B1 (en) 1993-03-29 2006-05-31 Kyowa Hakko Kogyo Co., Ltd. Alpha-1,3-fucosyltransferase
US5705614A (en) 1993-04-09 1998-01-06 Chiron Corporation Methods of producing antigen forks
JPH11507535A (ja) 1995-06-07 1999-07-06 イムクローン システムズ インコーポレイテッド 腫瘍の成長を抑制する抗体および抗体フラグメント類
AU690474B2 (en) 1995-09-11 1998-04-23 Kyowa Hakko Kirin Co., Ltd. Antibody againts alpha-chain of human interleukin 5 receptor
US6001358A (en) 1995-11-07 1999-12-14 Idec Pharmaceuticals Corporation Humanized antibodies to human gp39, compositions containing thereof
DK0979281T3 (da) 1997-05-02 2005-11-21 Genentech Inc Fremgangsmåde til fremstilling af multispecifikke antistoffer med heteromultimere og fælles bestanddele
US6235883B1 (en) 1997-05-05 2001-05-22 Abgenix, Inc. Human monoclonal antibodies to epidermal growth factor receptor
US6528624B1 (en) 1998-04-02 2003-03-04 Genentech, Inc. Polypeptide variants
US6737056B1 (en) 1999-01-15 2004-05-18 Genentech, Inc. Polypeptide variants with altered effector function
KR100940380B1 (ko) 1999-01-15 2010-02-02 제넨테크, 인크. 효과기 기능이 변화된 폴리펩티드 변이체
PT1176195E (pt) 1999-04-09 2013-07-18 Kyowa Hakko Kirin Co Ltd Processo para controlar a actividade de uma molécula funcional sob o ponto de vista imunológico
AU2001247616B2 (en) 2000-04-11 2007-06-14 Genentech, Inc. Multivalent antibodies and uses therefor
WO2001092340A2 (en) * 2000-05-26 2001-12-06 Immunex Corporation Use of interleukin-4 antagonists and compositions thereof
MXPA02012867A (es) 2000-06-29 2003-09-05 Abbott Lab Anticuerpos de especificidad doble y metodos para la elaboracion y el uso de los mismos.
DK2314686T4 (da) 2000-10-06 2023-08-21 Kyowa Kirin Co Ltd Celler, der danner antistofsammensætninger
CN1571797A (zh) 2001-10-15 2005-01-26 麒麟麦酒株式会社 抗hla-dr抗体
US7317091B2 (en) 2002-03-01 2008-01-08 Xencor, Inc. Optimized Fc variants
AU2004279742A1 (en) 2003-10-08 2005-04-21 Kyowa Hakko Kirin Co., Ltd. Fused protein composition
CA2580981C (en) 2004-09-22 2013-10-22 Kirin Beer Kabushiki Kaisha Stabilized human igg4 antibodies
US7923538B2 (en) 2005-07-22 2011-04-12 Kyowa Hakko Kirin Co., Ltd Recombinant antibody composition
US7612181B2 (en) 2005-08-19 2009-11-03 Abbott Laboratories Dual variable domain immunoglobulin and uses thereof
ES2828627T3 (es) * 2008-04-25 2021-05-27 Kyowa Kirin Co Ltd Anticuerpo multivalente estable
WO2010054007A1 (en) * 2008-11-07 2010-05-14 Fabrus Llc Combinatorial antibody libraries and uses thereof
RU2011151069A (ru) * 2009-05-15 2013-06-20 Чугаи Сейяку Кабусики Кайся Анти-axl антитело
EP2441831B9 (en) 2009-06-11 2019-03-06 Inter-University Research Institute Corporation Research Organization of Information and Systems Process for production of protein
WO2011116387A1 (en) 2010-03-19 2011-09-22 Tetragenetics, Inc. Production of aglycosylated monoclonal antibodies in ciliates
WO2012075037A1 (en) 2010-11-30 2012-06-07 Genentech, Inc. Low affinity blood brain barrier receptor antibodies and uses therefor
WO2012145469A1 (en) 2011-04-19 2012-10-26 The United States Of America, As Represented By The Secretary, Department Of Health & Human Services Human monoclonal antibodies specific for glypican-3 and use thereof
CN103534272B (zh) 2011-05-09 2016-05-11 株式会社英仙蛋白质科学 能够特异性识别转铁蛋白受体的抗体
US8691231B2 (en) 2011-06-03 2014-04-08 Merrimack Pharmaceuticals, Inc. Methods of treatment of tumors expressing predominantly high affinity EGFR ligands or tumors expressing predominantly low affinity EGFR ligands with monoclonal and oligoclonal anti-EGFR antibodies
PT2794905T (pt) 2011-12-20 2020-06-30 Medimmune Llc Polipéptidos modificados para estrutura de anticorpos bispecíficos
NZ631565A (en) 2012-03-14 2016-07-29 Regeneron Pharma Multispecific antigen-binding molecules and uses thereof
MX374424B (es) 2012-05-21 2025-03-06 Genentech Inc Metodos para mejorar la seguridad del transporte de la barrera hematoencefalica.
EA038367B1 (ru) 2013-05-20 2021-08-16 Дженентек, Инк. АНТИТЕЛА ПРОТИВ РЕЦЕПТОРА ТРАНСФЕРРИНА (TfR) И СПОСОБЫ ИХ ИСПОЛЬЗОВАНИЯ
CN104211814A (zh) 2013-05-29 2014-12-17 三星电子株式会社 用于消耗靶膜蛋白的组合物
AU2014358191B2 (en) * 2013-12-04 2020-12-24 Chugai Seiyaku Kabushiki Kaisha Antigen-binding molecules, the antigen-binding activity of which varies according to the concentration of compounds, and libraries of said molecules
JP2017511381A (ja) * 2014-04-04 2017-04-20 協和発酵キリン株式会社 アゴニスト活性が低減された抗デスレセプター3(dr3)アンタゴニスト抗体
WO2016081640A1 (en) * 2014-11-19 2016-05-26 Genentech, Inc. Anti-transferrin receptor / anti-bace1 multispecific antibodies and methods of use
JP6779876B2 (ja) * 2014-11-19 2020-11-04 ジェネンテック, インコーポレイテッド 抗トランスフェリン受容体抗体及びその使用方法
EP3243837A4 (en) * 2015-01-08 2018-12-05 Kyowa Hakko Kirin Co., Ltd. Bispecific antibody binding to trailr2 and psma
CR20210429A (es) * 2015-06-24 2021-09-24 Hoffmann La Roche ANTICUERPOS ANTI-RECEPTOR DE TRANSFERRINA CON AFINIDAD DISEÑADA (Divisional 2017-0562)
EP3323832A4 (en) * 2015-07-15 2018-12-26 Kyowa Hakko Kirin Co., Ltd. Antibody which specifically binds to human crth2
EP3454901A4 (en) 2016-05-09 2020-07-29 Annexon, Inc. COMPOSITIONS AND METHODS FOR TREATING PROGRESSIVE SPINAL AMYOTROPHY
KR102156626B1 (ko) 2018-07-16 2020-09-17 주식회사 셀바스에이아이 운동 처방 정보를 제공하는 서버 및 컴퓨터 프로그램

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