JP2023550632A - 眼の症状を処置するための製剤および方法 - Google Patents
眼の症状を処置するための製剤および方法 Download PDFInfo
- Publication number
- JP2023550632A JP2023550632A JP2023530994A JP2023530994A JP2023550632A JP 2023550632 A JP2023550632 A JP 2023550632A JP 2023530994 A JP2023530994 A JP 2023530994A JP 2023530994 A JP2023530994 A JP 2023530994A JP 2023550632 A JP2023550632 A JP 2023550632A
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical formulation
- administered
- azithromycin
- subject
- avermectin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/194—Carboxylic acids, e.g. valproic acid having two or more carboxyl groups, e.g. succinic, maleic or phthalic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/04—Artificial tears; Irrigation solutions
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Ophthalmology & Optometry (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063117393P | 2020-11-23 | 2020-11-23 | |
| US63/117,393 | 2020-11-23 | ||
| US202163254958P | 2021-10-12 | 2021-10-12 | |
| US63/254,958 | 2021-10-12 | ||
| PCT/US2021/060653 WO2022109497A1 (en) | 2020-11-23 | 2021-11-23 | Formulations and methods for treating conditions of the eye |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2023550632A true JP2023550632A (ja) | 2023-12-04 |
| JP2023550632A5 JP2023550632A5 (cg-RX-API-DMAC10.html) | 2024-11-29 |
Family
ID=81658809
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023530994A Pending JP2023550632A (ja) | 2020-11-23 | 2021-11-23 | 眼の症状を処置するための製剤および方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (5) | US20220160668A1 (cg-RX-API-DMAC10.html) |
| EP (1) | EP4247367A4 (cg-RX-API-DMAC10.html) |
| JP (1) | JP2023550632A (cg-RX-API-DMAC10.html) |
| AU (1) | AU2021381495A1 (cg-RX-API-DMAC10.html) |
| CA (1) | CA3199736A1 (cg-RX-API-DMAC10.html) |
| WO (1) | WO2022109497A1 (cg-RX-API-DMAC10.html) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9095412B2 (en) | 2012-03-20 | 2015-08-04 | Sight Sciences, Inc. | Ocular delivery systems and methods |
| US10299958B2 (en) | 2015-03-31 | 2019-05-28 | Sight Sciences, Inc. | Ocular delivery systems and methods |
| US11504270B1 (en) | 2019-09-27 | 2022-11-22 | Sight Sciences, Inc. | Ocular delivery systems and methods |
| US20220160668A1 (en) | 2020-11-23 | 2022-05-26 | Sight Sciences, Inc. | Formulations and methods for treating conditions of the eye |
| WO2022251710A2 (en) | 2021-05-28 | 2022-12-01 | Sight Sciences, Inc. | Intraocular devices, systems, and methods |
| US11877954B2 (en) | 2022-03-16 | 2024-01-23 | Sight Sciences, Inc. | Devices and methods for intraocular tissue manipulation |
| AU2023270196B2 (en) * | 2023-11-20 | 2025-06-26 | Dyer, Gordon Wayne DR | Method of Arthropod Egress |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2002540147A (ja) * | 1999-03-31 | 2002-11-26 | インサイト・ビジョン・インコーポレイテッド | 眼感染症の局所治療または予防 |
| JP2011527709A (ja) * | 2008-07-10 | 2011-11-04 | インスパイアー ファーマシューティカルズ,インコーポレイティド | 眼瞼炎の治療方法 |
| JP2014530044A (ja) * | 2011-09-14 | 2014-11-17 | フォーサイト・ビジョン5・インコーポレイテッドForsightvision5,Inc. | 眼挿入装置および方法 |
| JP2017526655A (ja) * | 2014-09-06 | 2017-09-14 | インテグラル バイオシステムズ エルエルシー | 眼において薬物徐放を達成する方法及び生体適合性組成物 |
Family Cites Families (56)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5614545A (en) | 1988-06-09 | 1997-03-25 | Leonard Bloom | Topical composition for treatment of blepharitis |
| US4957918A (en) | 1988-06-09 | 1990-09-18 | Leonard Bloom | Topical treatment of blepharitis |
| AT393454B (de) | 1989-10-04 | 1991-10-25 | Ido Dr Egerer | Augentropfenzusatz |
| US6107289A (en) | 1992-04-21 | 2000-08-22 | The Schepens Eye Research Institute, Inc. | Ocular therapy in keratoconjunctivitis sicca using topically applied androgens or TGF-β |
| RU2004118424A (ru) | 2001-11-19 | 2005-05-10 | Новартис АГ (CH) | Применение аскомицина для лечения блефарита |
| AR042890A1 (es) | 2003-01-16 | 2005-07-06 | Sucampo Pharmaceuticals Inc | Metodo de tratamiento del ojo seco con una composicion oftalmica que contiene un compuesto macrolido |
| KR20050092429A (ko) | 2003-01-22 | 2005-09-21 | 니찌방 가부시기가이샤 | 안질환 치료용 경피 흡수형 제제, 그 사용, 및 안질환치료약의 눈의 국소 조직으로의 이행 방법 |
| CA2597525A1 (en) | 2005-02-17 | 2006-08-24 | Senju Pharmaceutical Co., Ltd. | Solid ophthalmic drug for external use |
| US20070004672A1 (en) | 2005-07-01 | 2007-01-04 | Dharmendra Jani | Long lasting alginate dry eye, related methods of manufacture and methods of use |
| FR2891460B1 (fr) | 2005-09-30 | 2010-07-30 | Galderma Sa | Utilisation d'au moins un compose de la famille des avermectines pour le traitement des pathologies ophtalmiques dues au demodex folliculorum. |
| EP1964575B1 (en) | 2005-11-28 | 2015-09-23 | Senju Pharmaceutical Co., Ltd. | Pharmaceutical comprising ppar agonist |
| US20090318422A1 (en) | 2006-08-28 | 2009-12-24 | Akiharu Isowaki | Ophthalmic percutaneous absorption type preparation |
| US20080057022A1 (en) | 2006-08-30 | 2008-03-06 | Erning Xia | Ophthalmic Pharmaceutical Compositions and Uses Thereof |
| US7659259B2 (en) | 2006-12-21 | 2010-02-09 | Bausch & Lomb Incorporated | Method of treating inflammation of the eye |
| US20080312194A1 (en) | 2007-02-28 | 2008-12-18 | Ousler Iii George W | Methods and compositions for normalizing meibomian gland secretions |
| CA2685230C (en) * | 2007-05-04 | 2012-10-16 | Bausch & Lomb Incorporated | Compositions for reducing, ameliorating, treating, or preventing condition of dry eye and methods of making and using same |
| WO2008137826A2 (en) | 2007-05-07 | 2008-11-13 | Bausch & Lomb Incorporated | Compositions for reducing, ameliorating, treating, or preventing condition of dry eye and methods of making and using same |
| CA2753844A1 (en) | 2008-03-05 | 2009-09-11 | Vicus Therapeutics, Llc | Compositions and methods for mucositis and oncology therapies |
| US20110059925A1 (en) | 2008-03-26 | 2011-03-10 | Eric Donnenfeld | Methods for improving lid margin and tear film function and treatment of lid margin disease using tetracycline family antibiotics |
| WO2010085572A1 (en) | 2009-01-23 | 2010-07-29 | Inspire Pharmaceuticals, Inc. | Method of treating dry eye disease with azithromycin |
| FR2942138A1 (fr) | 2009-02-16 | 2010-08-20 | Galderma Res & Dev | Association de composes pour le traitement ou la prevention des affections dermatologiques |
| ES2752008T3 (es) | 2009-10-30 | 2020-04-02 | Intratus Inc | Métodos y composiciones para la liberación sostenida de fármacos |
| WO2011068786A2 (en) | 2009-12-02 | 2011-06-09 | Bridge Pharma, Inc. | Treating xerophthalmia with compounds increasing meibomian gland secretion |
| US9011861B2 (en) * | 2010-02-25 | 2015-04-21 | Schepens Eye Research Institute | Therapeutic compositions for the treatment of dry eye disease |
| AU2011287544B2 (en) | 2010-08-06 | 2014-12-11 | Galderma Research & Development | Combination of compounds for treating or preventing skin diseases |
| WO2012092375A1 (en) | 2010-12-29 | 2012-07-05 | Inspire Pharmaceuticals, Inc. | Method for treating dry eye |
| US8900626B2 (en) | 2011-06-20 | 2014-12-02 | Senju Usa, Inc. | Transdermal drug delivery system and method of using the same |
| WO2013003731A2 (en) | 2011-06-29 | 2013-01-03 | Insite Vision Incorporated | Methods of treating recurrent meibomian glands disorder and thereby decreasing the frequency of recurrence |
| EP2895144B1 (en) | 2012-09-12 | 2017-01-11 | Novaliq GmbH | Semifluorinated alkane compositions |
| MX363182B (es) | 2012-09-12 | 2019-03-13 | Novaliq Gmbh | Composiciones que comprenden mezclas de alcanos semifluorados. |
| CA2886042C (en) | 2012-09-28 | 2015-11-24 | Santen Pharmaceutical Co., Ltd. | Therapeutic or preventive agent for meibomian gland dysfunction or meibomian gland blockage |
| US9044508B2 (en) | 2013-03-15 | 2015-06-02 | Insite Vision Corporation | Concentrated aqueous azalide formulations |
| US20150141328A1 (en) * | 2013-11-18 | 2015-05-21 | The Schepens Eye Research Institute | Stimulation of human meibomian gland function |
| US20170232024A1 (en) | 2014-08-04 | 2017-08-17 | Jerry Tan Eye Surgery Pte Ltd | Pharmaceutical compositions for demodex related blepharitis and eyelid crusting |
| US9597328B2 (en) * | 2015-02-24 | 2017-03-21 | Ocugen, Inc. | Methods and compositions for treating dry eye disease and other eye disorders |
| US9393243B1 (en) | 2015-07-14 | 2016-07-19 | Nilesh Parikh | Topical Ciprofloxacin compositions |
| WO2017055924A2 (en) | 2015-09-28 | 2017-04-06 | M.G. Therapeutics Ltd. | Thiol and disulfide-containing agents for increasing meibomian gland lipid secretion |
| FR3041540B1 (fr) | 2015-09-29 | 2018-10-26 | Galderma Research & Development | Composition nettoyante auto-moussante a rincer, contenant de l'ivermectine. |
| WO2017089980A1 (en) | 2015-11-26 | 2017-06-01 | Cadila Healthcare Limited | Dual ppar modulators for the treatment of diabetic retinopathy and diabetic eye diseases |
| GB201522144D0 (en) | 2015-12-15 | 2016-01-27 | Univ Manchester | Compositions and uses and methods relating thereto |
| US9439917B1 (en) | 2015-12-28 | 2016-09-13 | Shetal Amit Shah | Anti-blepharitis compositions and their use |
| EA201891743A1 (ru) | 2016-02-04 | 2019-01-31 | Гордон Уэйн Дайер | Способ нарушения состояния касси-бакстера |
| US11260035B2 (en) | 2016-10-12 | 2022-03-01 | Ps Therapies Ltd | Topical compositions and methods of use thereof |
| EP3326608A1 (en) | 2016-11-24 | 2018-05-30 | Nestlé Skin Health SA | Composition comprising avermectin compounds without solid fatty substances |
| GB201706969D0 (en) | 2017-05-02 | 2017-06-14 | Medherant Ltd | Formulation |
| US20190008920A1 (en) * | 2017-05-19 | 2019-01-10 | Ocugen, Inc. | Ophthalmic compositions and methods of use |
| EP3644966A4 (en) | 2017-06-29 | 2021-03-24 | Advaite LLC | TREATMENT AND DIAGNOSIS OF EYE SURFACE DISORDERS |
| CA3080166A1 (en) | 2017-11-21 | 2019-05-31 | Axerovision, Inc. | Compositions and methods of use for treating aberrant inflammation in peri-ocular secretory glands or at the ocular surface |
| WO2019113475A1 (en) | 2017-12-07 | 2019-06-13 | Dermavant Sciences GmbH | Topical ointment formulations and their use in treating skin conditions |
| WO2020077284A1 (en) | 2018-10-12 | 2020-04-16 | Hovione Scientia | Macrocyclic lactone formulations, methods of their preparation and use of the formulations in treating pathologies secondary to ophthalmic parasites |
| US12161752B2 (en) * | 2019-08-20 | 2024-12-10 | Vishwanath Padmanabhan | Compositions and methods for the treatment of anterior blepharitis and posterior blepharitis |
| US20210052493A1 (en) | 2019-08-21 | 2021-02-25 | Joseph Sinclair | Non-aqueous anti-parasitic ointment for ophthalmological use |
| WO2021067823A2 (en) | 2019-10-05 | 2021-04-08 | The Schepens Eye Research Institute, Inc. | A new treatment for meibomian gland dysfunction |
| WO2021087051A1 (en) | 2019-10-30 | 2021-05-06 | Ps Therapy Ltd. | Topical compositions and methods of use thereof |
| US20220160668A1 (en) | 2020-11-23 | 2022-05-26 | Sight Sciences, Inc. | Formulations and methods for treating conditions of the eye |
| US11872213B2 (en) | 2021-01-28 | 2024-01-16 | Glaukos Corporation | Formulations |
-
2021
- 2021-11-23 US US17/534,348 patent/US20220160668A1/en not_active Abandoned
- 2021-11-23 EP EP21895840.3A patent/EP4247367A4/en not_active Withdrawn
- 2021-11-23 AU AU2021381495A patent/AU2021381495A1/en not_active Abandoned
- 2021-11-23 CA CA3199736A patent/CA3199736A1/en active Pending
- 2021-11-23 WO PCT/US2021/060653 patent/WO2022109497A1/en not_active Ceased
- 2021-11-23 US US17/534,349 patent/US11419886B2/en active Active
- 2021-11-23 JP JP2023530994A patent/JP2023550632A/ja active Pending
-
2022
- 2022-07-19 US US17/868,696 patent/US11554134B2/en active Active
- 2022-12-23 US US18/088,347 patent/US11925657B2/en active Active
-
2024
- 2024-02-01 US US18/430,551 patent/US20240415860A1/en not_active Abandoned
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2002540147A (ja) * | 1999-03-31 | 2002-11-26 | インサイト・ビジョン・インコーポレイテッド | 眼感染症の局所治療または予防 |
| JP2011527709A (ja) * | 2008-07-10 | 2011-11-04 | インスパイアー ファーマシューティカルズ,インコーポレイティド | 眼瞼炎の治療方法 |
| JP2014530044A (ja) * | 2011-09-14 | 2014-11-17 | フォーサイト・ビジョン5・インコーポレイテッドForsightvision5,Inc. | 眼挿入装置および方法 |
| JP2017526655A (ja) * | 2014-09-06 | 2017-09-14 | インテグラル バイオシステムズ エルエルシー | 眼において薬物徐放を達成する方法及び生体適合性組成物 |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2022109497A1 (en) | 2022-05-27 |
| US20220160668A1 (en) | 2022-05-26 |
| US11419886B2 (en) | 2022-08-23 |
| EP4247367A1 (en) | 2023-09-27 |
| CA3199736A1 (en) | 2022-05-27 |
| US11554134B2 (en) | 2023-01-17 |
| US20220354878A1 (en) | 2022-11-10 |
| US20240415860A1 (en) | 2024-12-19 |
| AU2021381495A1 (en) | 2023-06-22 |
| EP4247367A4 (en) | 2024-10-16 |
| US20230210878A1 (en) | 2023-07-06 |
| US20220160743A1 (en) | 2022-05-26 |
| US11925657B2 (en) | 2024-03-12 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US11925657B2 (en) | Formulations and methods for treating conditions of the eye | |
| JP2019518730A (ja) | 眼の炎症性障害および疾患の組合せ処置 | |
| EP2646010B1 (en) | Folic acid - ramipril combination: cellprotective, neuroprotective and retinoprotective ophtalmologic compositions | |
| TWI815423B (zh) | 用於治療近視的方法和藥物組合物 | |
| JP2023550632A5 (cg-RX-API-DMAC10.html) | ||
| JP2023512828A (ja) | クロマカリムプロドラッグ療法のための改善された方法及び組成物 | |
| US20110217262A1 (en) | Treatment of Ocular Surface Disorders by Increasing Conjunctival Vascular Permeability | |
| WO2015187840A2 (en) | Methods and formulations for treatment of ocular disorders | |
| EP4011450A1 (en) | Ophthalmic composition for promoting tear secretion | |
| KR20210010638A (ko) | 다이피리다몰을 이용하여 눈 장애를 치료하는데 사용하기 위한 조성물 | |
| US9901580B2 (en) | Methods of eye treatment using therapeutic compositions containing dipyridamole | |
| CN116710087A (zh) | 用于治疗眼部病症的制剂和方法 | |
| CN101432000B (zh) | 用于变应性眼病或变应性鼻病的包含三环性三唑并苯并氮杂*衍生物的预防剂或治疗剂 | |
| CN108348516A (zh) | 外用剂 | |
| RS66989B1 (sr) | Oftalmološke topikalne formulacije na bazi ksantana sa redukovanim režimom doziranja | |
| RU2836815C1 (ru) | Офтальмологические композиции для местного применения на ксантановой основе с сокращенным режимом дозирования | |
| Williams et al. | The birth of ocular pharmacology in the 20th century | |
| CN104721820A (zh) | 双特异性单克隆抗体在治疗葡萄膜炎中的用途 | |
| Mashael | Systemic Medications and Their Ocular Side Effects | |
| EA051764B1 (ru) | Офтальмологическая композиция, содержащая левофлоксацин и кеторолак, способ ее получения и ее применение | |
| CN117959316A (zh) | 一种包含恩格列净的药物组合物及其制备方法与制药用途 | |
| Hopkins | Therapeutic drugs | |
| HK40070050A (en) | Compositions and methods useable for treatment of dry eye | |
| HK40039952A (en) | Pharmaceutical compositions for controlling and/or reducing the progression of myopia | |
| EA047371B1 (ru) | Применение соединения при лечении сухости глаз или дискомфорта в глазах |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20241121 |
|
| A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20241121 |
|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20250818 |
|
| A977 | Report on retrieval |
Free format text: JAPANESE INTERMEDIATE CODE: A971007 Effective date: 20250829 |
|
| A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20251117 |
|
| A02 | Decision of refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A02 Effective date: 20260311 |