|
AU2003220970A1
(en)
|
2002-03-01 |
2003-09-16 |
Smithkline Beecham Corporation |
Diamino-pyrimidines and their use as angiogenesis inhibitors
|
|
US20050154202A1
(en)
|
2002-04-05 |
2005-07-14 |
Hagmann William K. |
Substituted aryl amides
|
|
NZ543482A
(en)
|
2003-05-21 |
2009-02-28 |
Prosidion Ltd |
Pyrrolopyridine-2-carboxylic acid amide inhibitors of glycogen phoshorylase
|
|
US7557211B2
(en)
|
2004-11-12 |
2009-07-07 |
Bristol-Myers Squibb Company |
8H-imidazo[4,5-D]thiazolo[4,5-B]pyridine based tricyclic compounds and pharmaceutical compositions comprising same
|
|
US7737279B2
(en)
|
2005-05-10 |
2010-06-15 |
Bristol-Myers Squibb Company |
1,6-dihydro-1,3,5,6-tetraaza-as-indacene based tricyclic compounds and pharmaceutical compositions comprising same
|
|
TW200803855A
(en)
|
2006-02-24 |
2008-01-16 |
Kalypsys Inc |
Quinolones useful as inducible nitric oxide synthase inhibitors
|
|
EP2114916A2
(en)
|
2007-02-02 |
2009-11-11 |
NeuroSearch A/S |
Pyridinyl-pyrazole derivatives and their use as potassium channel modulators
|
|
US8865732B2
(en)
|
2008-03-21 |
2014-10-21 |
Novartis Ag |
Heterocyclic compounds and uses thereof
|
|
TWI501967B
(zh)
|
2010-12-16 |
2015-10-01 |
Janssen R&D Ireland |
作為呼吸道融合病毒抗病毒劑之氮雜吲哚類
|
|
US9527925B2
(en)
|
2011-04-01 |
2016-12-27 |
Boehringer Ingelheim International Gmbh |
Bispecific binding molecules binding to VEGF and ANG2
|
|
WO2013056679A1
(en)
|
2011-10-21 |
2013-04-25 |
Beijing Hanmi Pharmaceutical Co., Ltd |
Novel heteroaryl-amino derivatives
|
|
AR090151A1
(es)
|
2012-03-07 |
2014-10-22 |
Lilly Co Eli |
Compuestos inhibidores de raf
|
|
JO3300B1
(ar)
|
2012-06-06 |
2018-09-16 |
Novartis Ag |
مركبات وتركيبات لتعديل نشاط egfr
|
|
US20150152083A1
(en)
|
2012-06-06 |
2015-06-04 |
Irm Llc, A Delaware Limited Liability Company |
Compounds and Compositions for Modulating EGFR Activity
|
|
MX2014014828A
(es)
*
|
2012-06-27 |
2015-02-12 |
Hoffmann La Roche |
Compuestos de 5-azaindazol y metodos de uso.
|
|
RU2660429C2
(ru)
|
2012-09-28 |
2018-07-06 |
Мерк Шарп И Доум Корп. |
Новые соединения, которые являются ингибиторами erk
|
|
WO2014081718A1
(en)
|
2012-11-20 |
2014-05-30 |
Genentech, Inc. |
Aminopyrimidine compounds as inhibitors of t790m containing egfr mutants
|
|
US9242969B2
(en)
|
2013-03-14 |
2016-01-26 |
Novartis Ag |
Biaryl amide compounds as kinase inhibitors
|
|
WO2014210354A1
(en)
|
2013-06-28 |
2014-12-31 |
Genentech, Inc. |
Azaindazole compounds as inhibitors of t790m containing egfr mutants
|
|
CN105658639A
(zh)
|
2013-08-22 |
2016-06-08 |
豪夫迈·罗氏有限公司 |
炔基醇和应用方法
|
|
CN104418858B
(zh)
|
2013-08-30 |
2018-12-11 |
浙江医药股份有限公司新昌制药厂 |
2,6-二含氮取代的嘌呤衍生物及其制备方法和其药物组合物与应用
|
|
WO2015094929A1
(en)
|
2013-12-18 |
2015-06-25 |
Merck Sharp & Dohme Corp. |
Erk inhibitors
|
|
LT3466955T
(lt)
|
2014-01-13 |
2021-02-25 |
Aurigene Discovery Technologies Limited |
Oksazol[4,5-b]piridino ir tiazol[4,5-b]piridino darinių, kaip irak4 inhibitorių, skirtų vėžio gydymui, gamybos būdas
|
|
JP6568926B2
(ja)
|
2014-03-20 |
2019-08-28 |
カペラ セラピューティクス，インコーポレーテッド |
癌の治療のためのｅｒｂｂチロシンキナーゼ阻害剤としてのベンゾイミダゾール誘導体
|
|
CA2943220C
(en)
|
2014-03-20 |
2024-01-16 |
Capella Therapeutics, Inc. |
Benzimidazole derivatives as erbb tyrosine kinase inhibitors for the treatment of cancer
|
|
CN105315285B
(zh)
*
|
2014-07-25 |
2017-12-08 |
上海海雁医药科技有限公司 |
2,4‑二取代7H‑吡咯并[2,3‑d]嘧啶衍生物、其制法与医药上的用途
|
|
EP3270694A4
(en)
*
|
2015-02-17 |
2018-09-05 |
Neupharma, Inc. |
Certain chemical entities, compositions, and methods
|
|
CN108012529A
(zh)
|
2015-05-15 |
2018-05-08 |
诺华股份有限公司 |
治疗egfr突变的癌症的方法
|
|
UA124090C2
(uk)
|
2015-06-03 |
2021-07-21 |
Прінсіпіа Байофарма Інк. |
Інгібітори тирозинкінази
|
|
JP6845165B2
(ja)
|
2015-06-30 |
2021-03-17 |
デイナ ファーバー キャンサー インスティチュート，インコーポレイテッド |
Ｅｇｆｒ阻害剤およびその使用方法
|
|
EP3347353B1
(en)
|
2015-09-11 |
2019-07-17 |
Boehringer Ingelheim International GmbH |
Pyrazolyl-substituted heteroaryls and their use as medicaments
|
|
TWI726968B
(zh)
|
2016-01-07 |
2021-05-11 |
開曼群島商Ｃｓ醫藥技術公司 |
Egfr酪胺酸激酶之臨床重要突變體之選擇性抑制劑
|
|
EP3535258B1
(en)
|
2016-11-03 |
2021-11-24 |
Bristol-Myers Squibb Company |
Substituted bicycle heterocyclic derivatives useful as romk channel inhibitors
|
|
US11198726B2
(en)
|
2017-06-02 |
2021-12-14 |
Boerhinger Ingelheim International Gmbh |
Anti-cancer combination therapy
|
|
EP3717471B1
(en)
|
2017-12-02 |
2022-01-05 |
Galapagos NV |
Novel compounds and pharmaceutical compositions thereof for the treatment of diseases
|
|
JP7313364B2
(ja)
*
|
2018-02-21 |
2023-07-24 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
Ｅｇｆｒ阻害剤としての新たなベンズイミダゾール化合物および誘導体
|
|
WO2020178316A1
(en)
*
|
2019-03-05 |
2020-09-10 |
Aziende Chimiche Riunite Angelini Francesco - A.C.R.A.F. S.P.A. |
5- or 7-azaindazoles as beta-lactamase inhibitors
|