JP2023547832A - 眼の適応症に対するベクター化抗ＴＮＦ－α抗体 - Google Patents

眼の適応症に対するベクター化抗ＴＮＦ－α抗体 Download PDF

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JP2023547832A
JP2023547832A JP2023524162A JP2023524162A JP2023547832A JP 2023547832 A JP2023547832 A JP 2023547832A JP 2023524162 A JP2023524162 A JP 2023524162A JP 2023524162 A JP2023524162 A JP 2023524162A JP 2023547832 A JP2023547832 A JP 2023547832A
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seq
amino acid
acid sequence
light chain
encoding
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JP2023547832A5 (https=
JPWO2022094106A5 (https=
Inventor
ワン，シュー
マクドゥーガルド，デヴィン
ブルーダー，ジョセフ
リウ，イェ
ダノス，オリビエ
リー，ウェイ－ファ
チャオ，チャンピング
バドジンスキ，エワ
ヒギンス，ミカイラ
シ，ミ
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リジェネックスバイオ インコーポレイテッド
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Publication of JP2023547832A5 publication Critical patent/JP2023547832A5/ja
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    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/241—Tumor Necrosis Factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
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    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • C—CHEMISTRY; METALLURGY
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    • C07K2317/00—Immunoglobulins specific features
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    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
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    • C12N2710/10011—Adenoviridae
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    • C12N2750/00011—Details
    • C12N2750/14011—Parvoviridae
    • C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
    • C12N2750/14141—Use of virus, viral particle or viral elements as a vector
    • C12N2750/14145—Special targeting system for viral vectors

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  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
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  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
JP2023524162A 2020-10-28 2021-10-28 眼の適応症に対するベクター化抗ＴＮＦ－α抗体 Pending JP2023547832A (ja)

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US202063106832P 2020-10-28 2020-10-28
US63/106,832 2020-10-28
PCT/US2021/057084 WO2022094106A1 (en) 2020-10-28 2021-10-28 VECTORIZED ANTI-TNF-α ANTIBODIES FOR OCULAR INDICATIONS

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JP2023547832A true JP2023547832A (ja) 2023-11-14
JP2023547832A5 JP2023547832A5 (https=) 2024-10-29
JPWO2022094106A5 JPWO2022094106A5 (https=) 2024-10-29

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US (1) US20230391864A1 (https=)
EP (1) EP4236999A1 (https=)
JP (1) JP2023547832A (https=)
KR (1) KR20230093437A (https=)
CN (1) CN116528892A (https=)
AR (1) AR123948A1 (https=)
AU (1) AU2021371307A1 (https=)
CA (1) CA3195967A1 (https=)
IL (1) IL302279A (https=)
MX (1) MX2023004806A (https=)
TW (1) TW202233841A (https=)
WO (1) WO2022094106A1 (https=)

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WO2024003578A1 (en) * 2022-07-01 2024-01-04 The University Of Bristol Vector comprising a sequence encoding an anti-tnf antibody and an inflammation-inducible promoter
EP4627095A2 (en) * 2022-11-28 2025-10-08 Siren Biotechnology, Inc. Gene therapy vectors for treatment of cancer

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MX2023004806A (es) 2023-05-10
WO2022094106A1 (en) 2022-05-05
KR20230093437A (ko) 2023-06-27
US20230391864A1 (en) 2023-12-07
AR123948A1 (es) 2023-01-25
AU2021371307A9 (en) 2024-09-19
EP4236999A1 (en) 2023-09-06
CA3195967A1 (en) 2022-05-05
AU2021371307A1 (en) 2023-06-01
IL302279A (en) 2023-06-01
CN116528892A (zh) 2023-08-01
TW202233841A (zh) 2022-09-01

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