JP2023539870A5 - - Google Patents

Info

Publication number
JP2023539870A5
JP2023539870A5 JP2023513564A JP2023513564A JP2023539870A5 JP 2023539870 A5 JP2023539870 A5 JP 2023539870A5 JP 2023513564 A JP2023513564 A JP 2023513564A JP 2023513564 A JP2023513564 A JP 2023513564A JP 2023539870 A5 JP2023539870 A5 JP 2023539870A5
Authority
JP
Japan
Prior art keywords
seq
region
amino acid
acid sequence
cells
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023513564A
Other languages
English (en)
Japanese (ja)
Other versions
JP2023539870A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2021/047600 external-priority patent/WO2022046935A2/en
Publication of JP2023539870A publication Critical patent/JP2023539870A/ja
Publication of JP2023539870A5 publication Critical patent/JP2023539870A5/ja
Pending legal-status Critical Current

Links

JP2023513564A 2020-08-26 2021-08-25 グリア芽細胞腫を処置するための方法および組成物 Pending JP2023539870A (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US202063070550P 2020-08-26 2020-08-26
US63/070,550 2020-08-26
US202163171187P 2021-04-06 2021-04-06
US63/171,187 2021-04-06
US202163218761P 2021-07-06 2021-07-06
US63/218,761 2021-07-06
PCT/US2021/047600 WO2022046935A2 (en) 2020-08-26 2021-08-25 Methods and compositions for treating glioblastoma

Publications (2)

Publication Number Publication Date
JP2023539870A JP2023539870A (ja) 2023-09-20
JP2023539870A5 true JP2023539870A5 (enExample) 2024-09-02

Family

ID=80352963

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2023513567A Pending JP2023539871A (ja) 2020-08-26 2021-08-25 グリア芽細胞腫を処置するための方法および組成物
JP2023513564A Pending JP2023539870A (ja) 2020-08-26 2021-08-25 グリア芽細胞腫を処置するための方法および組成物

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP2023513567A Pending JP2023539871A (ja) 2020-08-26 2021-08-25 グリア芽細胞腫を処置するための方法および組成物

Country Status (6)

Country Link
US (2) US20230364139A1 (enExample)
EP (2) EP4204443A4 (enExample)
JP (2) JP2023539871A (enExample)
CN (2) CN116348482A (enExample)
CA (2) CA3193009A1 (enExample)
WO (2) WO2022046938A1 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3568466A4 (en) 2017-01-10 2020-07-15 The General Hospital Corporation TARGETED T CELLS WITH CYTOTOXICITY TO IMMUNOSUPPRESSIVE CELLS
US12378297B2 (en) 2017-04-14 2025-08-05 The General Hospital Corporation Chimeric antigen receptor T cells targeting the tumor microenvironment
WO2019157533A1 (en) * 2018-02-12 2019-08-15 The General Hospital Corporation Chimeric antigen receptors targeting the tumor microenvironment
JP2023539871A (ja) * 2020-08-26 2023-09-20 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア グリア芽細胞腫を処置するための方法および組成物
CN116555204B (zh) * 2023-07-04 2023-09-12 苏州驾玉生物医药有限公司 一种性能提升的突变荧光素酶及其应用
WO2025096603A1 (en) * 2023-10-30 2025-05-08 City Of Hope Targeted chimeric antigen receptor modified t cells for treatment of il13ralpha2 positive malignancies
WO2025193475A1 (en) * 2024-03-14 2025-09-18 The Regents Of The University Of California Enhancing immune cell innate and adaptive responses

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6884603B2 (en) * 1998-04-03 2005-04-26 The Penn State Research Foundation Nucleic acids encoding IL13 mutants
EP2331566B1 (en) * 2008-08-26 2015-10-07 City of Hope Method and compositions for enhanced anti-tumor effector functioning of t cells
CA2861491C (en) * 2012-02-13 2020-08-25 Seattle Children's Hospital D/B/A Seattle Children's Research Institute Bispecific chimeric antigen receptors and therapeutic uses thereof
JP2017537622A (ja) * 2014-12-02 2017-12-21 ロジャー・ウィリアムズ・ホスピタル がんを治療するための方法及び組成物
JP6821688B2 (ja) * 2015-10-09 2021-01-27 ミルテニー・バイオテク・テクノロジー・インコーポレイテッドMiltenyi Biotec Technology, Inc. キメラ抗原受容体および使用方法
PL3368571T3 (pl) * 2015-10-30 2023-05-02 The Regents Of The University Of California Polipeptydy odpowiadające na transformujący czynnik wzrostu beta i sposoby ich zastosowania
EP3202783A1 (en) * 2016-02-02 2017-08-09 Ecole Polytechnique Fédérale de Lausanne (EPFL) Engineered antigen presenting cells and uses thereof
US20180100016A1 (en) * 2016-12-22 2018-04-12 Xiaotong Song Use of car-modified human natural killer cells to treat cancer
BR112019017256A2 (pt) * 2017-02-20 2020-04-14 Dragonfly Therapeutics Inc proteínas de ligação gd2, nkg2d e cd16
CA3095757A1 (en) * 2018-04-06 2019-10-10 The Regents Of The University Of California Methods of treating glioblastomas
JP2023539871A (ja) * 2020-08-26 2023-09-20 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア グリア芽細胞腫を処置するための方法および組成物

Similar Documents

Publication Publication Date Title
JP2023539870A5 (enExample)
JP2023539871A5 (enExample)
CA2942459C (en) Claudin-6-specific immunoreceptors and t cell epitopes
RU2685479C2 (ru) Химерный антигенный рецептор
JP2023534928A (ja) 改変免疫細胞及びその使用
JP2022513148A (ja) T細胞の改変
JP2016528899A (ja) 抗cd30キメラ抗原受容体およびその使用
WO2017028374A1 (en) Construct, genetically modified lymphocyte, preparation method and usage thereof
WO2019096115A1 (zh) 分离的t细胞受体、其修饰的细胞、编码核酸、表达载体、制备方法、药物组合物和应用
CN110857319B (zh) 一种分离的t细胞受体、其修饰的细胞、编码核酸及其应用
CN113896801B (zh) 靶向人Claudin18.2和NKG2DL的嵌合抗原受体细胞及其制备方法和应用
CA2700942A1 (en) An ex vivo, fast and efficient process to obtain activated antigen-presenting cells that are useful for therapies against cancer and immune system-related diseases
CA3174248A1 (en) Codon-optimized nucleotide sequences encoding an ap-1 transcription factor
JP2023532280A (ja) 免疫細胞のmRNAトランスフェクション
US20260042813A1 (en) Natural killer cell products and methods
US20230398216A1 (en) Chimeric activation receptors
JP2023524873A (ja) 方法
US20230030680A1 (en) Chimeric gmcsf-il18 receptor
EP4293041A1 (en) Amplification enhancer and use thereof
JP7748934B2 (ja) ユニバーサルcar-t細胞ならびにその調製および用途
WO2023051361A1 (zh) 工程化免疫细胞及其用途
CN111499766B (zh) 针对慢性淋巴细胞白血病的免疫效应细胞、其制备方法和应用
WO2023035947A1 (zh) 工程化免疫细胞及其用途
WO2021115333A1 (zh) 一种融合蛋白及表达此蛋白的工程化免疫细胞及其应用
CN113993991A (zh) 宿主细胞中免疫蛋白酶体的过表达用于产生抗原呈递细胞