JP2023535926A5 - - Google Patents

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Publication number
JP2023535926A5
JP2023535926A5 JP2023504487A JP2023504487A JP2023535926A5 JP 2023535926 A5 JP2023535926 A5 JP 2023535926A5 JP 2023504487 A JP2023504487 A JP 2023504487A JP 2023504487 A JP2023504487 A JP 2023504487A JP 2023535926 A5 JP2023535926 A5 JP 2023535926A5
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JP
Japan
Prior art keywords
branched
linear
independently selected
alkyl
hydrogen atom
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JP2023504487A
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English (en)
Japanese (ja)
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JP2023535926A (ja
JP7797473B2 (ja
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Priority claimed from PCT/CN2021/107774 external-priority patent/WO2022017440A1/zh
Publication of JP2023535926A publication Critical patent/JP2023535926A/ja
Publication of JP2023535926A5 publication Critical patent/JP2023535926A5/ja
Priority to JP2025280400A priority Critical patent/JP2026065019A/ja
Application granted granted Critical
Publication of JP7797473B2 publication Critical patent/JP7797473B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2023504487A 2020-07-22 2021-07-22 ５－ｈｔ２ａ受容体阻害剤又は逆作動薬、その調製方法、及びその用途 Active JP7797473B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2025280400A JP2026065019A (ja) 2020-07-22 2025-12-24 ５－ｈｔ２ａ受容体阻害剤又は逆作動薬、その調製方法、及びその用途

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
CN202010708352 2020-07-22
CN202010708352.8 2020-07-22
CN202110364023.0 2021-04-03
CN202110364023 2021-04-03
PCT/CN2021/107774 WO2022017440A1 (zh) 2020-07-22 2021-07-22 5-ht 2a受体抑制剂或反向激动剂及其制备方法和应用

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2025280400A Division JP2026065019A (ja) 2020-07-22 2025-12-24 ５－ｈｔ２ａ受容体阻害剤又は逆作動薬、その調製方法、及びその用途

Publications (3)

Publication Number Publication Date
JP2023535926A JP2023535926A (ja) 2023-08-22
JP2023535926A5 true JP2023535926A5 (enExample) 2024-07-24
JP7797473B2 JP7797473B2 (ja) 2026-01-13

Family

ID=79728503

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2023504487A Active JP7797473B2 (ja) 2020-07-22 2021-07-22 ５－ｈｔ２ａ受容体阻害剤又は逆作動薬、その調製方法、及びその用途
JP2025280400A Pending JP2026065019A (ja) 2020-07-22 2025-12-24 ５－ｈｔ２ａ受容体阻害剤又は逆作動薬、その調製方法、及びその用途

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2025280400A Pending JP2026065019A (ja) 2020-07-22 2025-12-24 ５－ｈｔ２ａ受容体阻害剤又は逆作動薬、その調製方法、及びその用途

Country Status (5)

Country Link
US (1) US20230348421A1 (enExample)
EP (1) EP4186893A4 (enExample)
JP (2) JP7797473B2 (enExample)
CN (2) CN114728933B (enExample)
WO (1) WO2022017440A1 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2021193790A1 (ja) 2020-03-26 2021-09-30 塩野義製薬株式会社 セロトニン受容体結合活性を有する芳香族複素環誘導体
JP7741820B2 (ja) * 2020-12-28 2025-09-18 塩野義製薬株式会社 セロトニン受容体結合活性を有する環状アミン誘導体
AU2023319750A1 (en) * 2022-08-03 2025-02-13 Luye Innomind Pharma Shijiazhuang Co., Ltd. 5-ht2a receptor inverse agonist, and preparation method therefor and use thereof
CN115850204B (zh) * 2022-11-26 2024-01-19 烟台大学 四氢苯并噻吩衍生物及其制备方法和应用
WO2025162237A1 (zh) * 2024-02-02 2025-08-07 绿叶嘉奥制药石家庄有限公司 一种5-ht2a受体反向激动剂的盐型、晶型及其制备方法和应用

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US3829307A (en) * 1971-04-30 1974-08-13 Stauffer Chemical Co 1-picolyl-3-phenyl ureas and their utility as herbicides
US3991195A (en) * 1974-05-06 1976-11-09 Stauffer Chemical Company Method of controlling bacteria
DK485176A (da) * 1975-11-12 1977-05-13 Merck & Co Inc Fremgangsmade til fremstilling af pyridylurinstoffer
FR2802206B1 (fr) * 1999-12-14 2005-04-22 Sod Conseils Rech Applic Derives de 4-aminopiperidine et leur utilisation en tant que medicament
EP1263729B1 (en) * 2000-03-06 2006-12-20 Acadia Pharmaceuticals Inc. Azacyclic compounds for use in the treatment of serotonin related diseases
KR20050008846A (ko) * 2002-06-24 2005-01-21 아카디아 파마슈티칼스 인코포레이티드 세로토닌 수용체 제제로서의 ｎ-치환된 피페리딘 유도체
CA2512639C (en) 2003-01-16 2012-10-30 Acadia Pharmaceuticals Inc. Selective serotonin 2a/2c receptor inverse agonists as therapeutics for neurodegenerative diseases
US20050261278A1 (en) * 2004-05-21 2005-11-24 Weiner David M Selective serotonin receptor inverse agonists as therapeutics for disease
US20120183600A1 (en) * 2007-01-16 2012-07-19 Chien-Hung Chen Novel composition for treating metabolic syndrome and other conditions
US20080280886A1 (en) * 2007-05-08 2008-11-13 Auspex Pharmaceuticals, Inc. Substituted ureas
WO2009039461A2 (en) * 2007-09-21 2009-03-26 Acadia Pharmaceuticals, Inc. N-substituted piperidine derivatives as serotonin receptor agents
EP2195302B1 (en) * 2007-10-09 2015-02-18 Dow AgroSciences LLC Insecticidal substituted azinyl derivatives
WO2010111353A1 (en) * 2009-03-25 2010-09-30 Acadia Pharmaceuticals, Inc. N-substituted piperidine derivatives as serotonin receptor agents
WO2010141696A1 (en) * 2009-06-04 2010-12-09 Dara Biosciences, Inc. Methods of treating or preventing psoriasis, and/or alzheimer's disease using indane acetic acid derivatives
JP2016513734A (ja) * 2013-03-15 2016-05-16 エーエルエス マウンテン リミテッド ライアビリティ カンパニー Ａｍｐｋ活性化剤及びセロトニン作動薬を含む医薬組成物並びにそれらの使用方法
TWI703130B (zh) * 2014-03-07 2020-09-01 瑞士商赫爾辛保健股份有限公司 對位取代的不對稱脲及其醫療用途
WO2017172757A1 (en) * 2016-03-29 2017-10-05 Acadia Pharmaceuticals Inc. 5-ht2a serotonin receptor inverse agonists or antagonists for use in reducing amyloid-beta peptides and accumulation of amyloid plaques
CN109111385B (zh) * 2017-06-23 2023-06-30 上海翰森生物医药科技有限公司 5-ht2a受体抑制剂及其制备方法和应用
MX2020001757A (es) * 2017-08-21 2020-09-07 Acadia Pharm Inc Compuestos, sales de los mismos y metodos para el tratamiento de enfermedades.
WO2019040106A2 (en) * 2017-08-21 2019-02-28 Acadia Pharmaceuticals Inc. COMPOUNDS, RELATED SALTS AND METHODS FOR THE TREATMENT OF DISEASES
CN113214141B (zh) * 2020-01-21 2022-04-08 瀚远医药有限公司 5ht2a受体拮抗剂及其制备和应用
WO2021193790A1 (ja) 2020-03-26 2021-09-30 塩野義製薬株式会社 セロトニン受容体結合活性を有する芳香族複素環誘導体
AU2023319750A1 (en) * 2022-08-03 2025-02-13 Luye Innomind Pharma Shijiazhuang Co., Ltd. 5-ht2a receptor inverse agonist, and preparation method therefor and use thereof

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