JP2023535598A5 - - Google Patents
Info
- Publication number
- JP2023535598A5 JP2023535598A5 JP2023505412A JP2023505412A JP2023535598A5 JP 2023535598 A5 JP2023535598 A5 JP 2023535598A5 JP 2023505412 A JP2023505412 A JP 2023505412A JP 2023505412 A JP2023505412 A JP 2023505412A JP 2023535598 A5 JP2023535598 A5 JP 2023535598A5
- Authority
- JP
- Japan
- Prior art keywords
- groups
- ligand
- group
- solvate
- pharmaceutically acceptable
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010730899.8 | 2020-07-27 | ||
| CN202010730899 | 2020-07-27 | ||
| CN202010735910 | 2020-07-28 | ||
| CN202010735910.X | 2020-07-28 | ||
| PCT/CN2021/108666 WO2022022508A1 (zh) | 2020-07-27 | 2021-07-27 | 抗cd79b抗体药物偶联物、其制备方法及其医药用途 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023535598A JP2023535598A (ja) | 2023-08-18 |
| JP2023535598A5 true JP2023535598A5 (enExample) | 2024-08-27 |
| JP7817236B2 JP7817236B2 (ja) | 2026-02-18 |
Family
ID=80037618
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023505412A Active JP7817236B2 (ja) | 2020-07-27 | 2021-07-27 | 抗ｃｄ７９ｂ抗体薬物複合体、その調製方法及びその医薬用途 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US12642862B2 (enExample) |
| EP (1) | EP4190812A4 (enExample) |
| JP (1) | JP7817236B2 (enExample) |
| KR (1) | KR20230044275A (enExample) |
| CN (1) | CN115698079A (enExample) |
| AU (1) | AU2021317378A1 (enExample) |
| BR (1) | BR112023001359A2 (enExample) |
| CA (1) | CA3184724A1 (enExample) |
| MX (1) | MX2023001163A (enExample) |
| TW (1) | TWI888610B (enExample) |
| WO (1) | WO2022022508A1 (enExample) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP7821733B2 (ja) * | 2020-01-22 | 2026-02-27 | 上海森輝医薬有限公司 | エリブリン誘導体の薬物複合体、その調製方法及びその医薬的応用 |
| MX2024000893A (es) * | 2021-07-22 | 2024-02-06 | Shanghai Senhui Medicine Co Ltd | Farmaco conjugado de un derivado de eribulina. |
| EP4393514A1 (en) * | 2021-08-24 | 2024-07-03 | Kunshan Xinyunda Biotech Co., Ltd. | Antibody-drug conjugate conjugated via breakable linker |
| IL311324A (en) * | 2021-09-16 | 2024-05-01 | Chia Tai Tianqing Pharmaceutical Group Co Ltd | A drug-antibody conjugate against HER3, a preparation including it and its use |
| JP7767613B2 (ja) | 2021-11-15 | 2025-11-11 | システィミューン，インコーポレイテッド | 二重特異性抗体－カンプトテシン薬物複合体及びその製薬的使用 |
| CA3248952A1 (en) * | 2022-01-26 | 2025-07-10 | Shanghai Mabgen Biotech Ltd. | PHARMACEUTICAL COMPOSITION COMPRISING AN ANTI-CD79B ANTIBODY-DRUG CONJUGATE AND ITS USE |
| EP4480499A1 (en) * | 2022-02-16 | 2024-12-25 | Medilink Therapeutics (Suzhou) Co., Ltd. | Conjugate of antibody-eribulin or derivative thereof, intermediate thereof, preparation method therefor, pharmaceutical composition thereof and use thereof |
| KR20240150773A (ko) * | 2022-02-24 | 2024-10-16 | 에보포인트 바이오사이언시스 컴퍼니 리미티드 | 항체 및 약물 접합체 및 이의 용도 |
| CN119998325A (zh) * | 2022-08-08 | 2025-05-13 | Atb治疗公司 | 抗CD79b的人源化抗体 |
| WO2024078612A1 (en) * | 2022-10-14 | 2024-04-18 | Genequantum Healthcare (Suzhou) Co., Ltd. | Linker-payload compound, conjugates and applications thereof |
| CN117917248A (zh) * | 2022-10-20 | 2024-04-23 | 英诺湖医药(杭州)有限公司 | 酶裂解连接子及包含其的配体-艾瑞布林偶联物 |
| EP4623936A1 (en) * | 2022-11-22 | 2025-10-01 | Keymed Biosciences (Chengdu) Co., Ltd. | Fused ring compound, conjugate thereof and use thereof |
| CN118271439B (zh) * | 2022-12-29 | 2025-06-13 | 深圳泽安生物医药有限公司 | 抗CD79b抗体及其用途 |
| KR20250143351A (ko) * | 2023-04-12 | 2025-10-01 | 레메젠 코, 리미티드 | 모노메틸 아우리스타틴 e 화합물의 제조 및 정제 방법 |
| WO2025162492A1 (zh) * | 2024-01-29 | 2025-08-07 | 甘李药业股份有限公司 | 一种连接子、配体-药物偶联物及其医药用途 |
| CN122514386A (zh) * | 2024-02-02 | 2026-08-04 | 江苏恒瑞医药股份有限公司 | 抗CD79b抗体药物偶联物联合免疫治疗剂、化疗剂治疗肿瘤 |
| WO2025209279A1 (zh) * | 2024-04-03 | 2025-10-09 | 英诺湖医药(杭州)有限公司 | 一种抗b7h3抗体-艾瑞布林偶联物及其应用 |
| WO2026006252A1 (en) * | 2024-06-25 | 2026-01-02 | Abbvie Inc. | Anti-cd79b antibody drug conjugates |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5208020A (en) | 1989-10-25 | 1993-05-04 | Immunogen Inc. | Cytotoxic agents comprising maytansinoids and their therapeutic use |
| GB9112536D0 (en) | 1991-06-11 | 1991-07-31 | Celltech Ltd | Chemical compounds |
| US6884869B2 (en) | 2001-04-30 | 2005-04-26 | Seattle Genetics, Inc. | Pentapeptide compounds and uses related thereto |
| US20090068178A1 (en) | 2002-05-08 | 2009-03-12 | Genentech, Inc. | Compositions and Methods for the Treatment of Tumor of Hematopoietic Origin |
| PT1644412E (pt) | 2003-07-01 | 2015-12-23 | Ucb Biopharma Sprl | Fragmentos de anticorpos fab modificados |
| GB0315450D0 (en) | 2003-07-01 | 2003-08-06 | Celltech R&D Ltd | Biological products |
| GB0315457D0 (en) | 2003-07-01 | 2003-08-06 | Celltech R&D Ltd | Biological products |
| ES2605443T3 (es) | 2003-11-06 | 2017-03-14 | Seattle Genetics, Inc. | Conjugados de auristatina con anticuerpos anti-HER2 o anti-CD22 y su uso en terapia |
| GB0411186D0 (en) | 2004-05-19 | 2004-06-23 | Celltech R&D Ltd | Biological products |
| AU2016273960B2 (en) * | 2007-07-16 | 2019-01-24 | Genentech, Inc. | Anti-CD79b antibodies and immunoconjugates and methods of use |
| PE20140625A1 (es) * | 2007-07-16 | 2014-05-29 | Genentech Inc | ANTICUERPOS ANTI-CD79b E INMUNOCONJUGADOS HUMANIZADOS |
| EP2535350B1 (en) | 2007-09-26 | 2018-01-24 | UCB Biopharma SPRL | Dual specificity antibody fusions |
| DK2657253T3 (en) * | 2008-01-31 | 2017-10-09 | Genentech Inc | Anti-CD79b antibodies and immune conjugates and methods of use |
| US10407513B2 (en) | 2008-09-26 | 2019-09-10 | Ucb Biopharma Sprl | Biological products |
| SI2992016T1 (en) | 2013-05-02 | 2018-01-31 | F. Hoffmann-La Roche Ag | Combination therapy of an afucosylated cd20 antibody with a cd79b antibody-drug conjugate |
| CA2979671C (en) * | 2014-09-23 | 2020-03-10 | Genentech, Inc. | Methods of using anti-cd79b immunoconjugates |
| MX386587B (es) | 2014-12-05 | 2025-03-19 | Genentech Inc | ANTICUERPOS ANTI-CD79b Y MÉTODOS DE USO. |
| JP2019510000A (ja) | 2016-02-26 | 2019-04-11 | ジエンス ヘンルイ メデイシンカンパニー リミテッドＪｉａｎｇｓｕ Ｈｅｎｇｒｕｉ Ｍｅｄｉｃｉｎｅ Ｃｏ．，Ｌｔｄ． | 新規トキシン及びその中間体の製造方法 |
| JOP20190187A1 (ar) | 2017-02-03 | 2019-08-01 | Novartis Ag | مترافقات عقار جسم مضاد لـ ccr7 |
| CR20250325A (es) * | 2018-04-13 | 2025-08-29 | Genentech Inc | Formulaciones inmunoconjugadas anti-cd79b estables (divisional expediente 2020-0550) |
| UA130338C2 (uk) | 2018-09-26 | 2026-01-28 | Джянгсу Хенгруй Медісін Ко., Лтд. | Кон'югат ліганд-лікарський засіб аналога ексатекану, спосіб його отримання та його застосування |
| JP7408646B2 (ja) | 2018-09-30 | 2024-01-05 | ジエンス ハンソー ファーマスーティカル グループ カンパニー リミテッド | 抗－ｂ７ｈ３抗体－エキサテカンアナログコンジュゲート及びその医薬用途 |
| CN111116745B (zh) * | 2018-11-01 | 2022-10-14 | 上海新理念生物医药科技有限公司 | 抗CD79b抗体、其药物偶联物及其应用 |
| CA3127556A1 (en) * | 2019-01-28 | 2020-08-06 | Tuojie Biotech (Shanghai) Co., Ltd. | Anti-cd79b antibody, antigen-binding fragment thereof, and pharmaceutical use thereof |
| JP7821733B2 (ja) * | 2020-01-22 | 2026-02-27 | 上海森輝医薬有限公司 | エリブリン誘導体の薬物複合体、その調製方法及びその医薬的応用 |
-
2021
- 2021-07-27 EP EP21849525.7A patent/EP4190812A4/en active Pending
- 2021-07-27 TW TW110127556A patent/TWI888610B/zh active
- 2021-07-27 WO PCT/CN2021/108666 patent/WO2022022508A1/zh not_active Ceased
- 2021-07-27 CA CA3184724A patent/CA3184724A1/en active Pending
- 2021-07-27 JP JP2023505412A patent/JP7817236B2/ja active Active
- 2021-07-27 BR BR112023001359A patent/BR112023001359A2/pt unknown
- 2021-07-27 AU AU2021317378A patent/AU2021317378A1/en active Pending
- 2021-07-27 MX MX2023001163A patent/MX2023001163A/es unknown
- 2021-07-27 US US18/018,241 patent/US12642862B2/en active Active
- 2021-07-27 CN CN202180042603.6A patent/CN115698079A/zh active Pending
- 2021-07-27 KR KR1020237006821A patent/KR20230044275A/ko active Pending
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