JP2023519261A5 - - Google Patents
Info
- Publication number
- JP2023519261A5 JP2023519261A5 JP2022557789A JP2022557789A JP2023519261A5 JP 2023519261 A5 JP2023519261 A5 JP 2023519261A5 JP 2022557789 A JP2022557789 A JP 2022557789A JP 2022557789 A JP2022557789 A JP 2022557789A JP 2023519261 A5 JP2023519261 A5 JP 2023519261A5
- Authority
- JP
- Japan
- Prior art keywords
- groups
- antibody
- cancer
- pharmaceutically acceptable
- drug conjugate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010218297 | 2020-03-25 | ||
| CN202010218297.4 | 2020-03-25 | ||
| PCT/CN2021/082857 WO2021190583A1 (zh) | 2020-03-25 | 2021-03-25 | 抗psma抗体-依喜替康类似物偶联物及其医药用途 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2023519261A JP2023519261A (ja) | 2023-05-10 |
| JP2023519261A5 true JP2023519261A5 (enExample) | 2024-04-02 |
Family
ID=77890968
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022557789A Pending JP2023519261A (ja) | 2020-03-25 | 2021-03-25 | 抗ｐｓｍａ抗体－エキサテカン類似体複合体及びその医薬用途 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20230140397A1 (enExample) |
| EP (1) | EP4130006A4 (enExample) |
| JP (1) | JP2023519261A (enExample) |
| KR (1) | KR20220160016A (enExample) |
| CN (1) | CN115298186B (enExample) |
| AU (1) | AU2021240756A1 (enExample) |
| BR (1) | BR112022019027A2 (enExample) |
| CA (1) | CA3177279A1 (enExample) |
| MX (1) | MX2022011808A (enExample) |
| TW (1) | TWI888517B (enExample) |
| WO (1) | WO2021190583A1 (enExample) |
| ZA (1) | ZA202210724B (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP7767613B2 (ja) | 2021-11-15 | 2025-11-11 | システィミューン，インコーポレイテッド | 二重特異性抗体－カンプトテシン薬物複合体及びその製薬的使用 |
| US11814394B2 (en) | 2021-11-16 | 2023-11-14 | Genequantum Healthcare (Suzhou) Co., Ltd. | Exatecan derivatives, linker-payloads, and conjugates and thereof |
| WO2024012566A2 (en) | 2022-07-15 | 2024-01-18 | Genequantum Healthcare (Suzhou) Co., Ltd. | Antibody, linkers, payload, conjugates and applications thereof |
| KR20260040624A (ko) * | 2023-07-25 | 2026-03-25 | 지앙수 헨그루이 파마슈티컬스 컴퍼니 리미티드 | c-Met를 표적으로 하는 항체-약물 접합체 및 이의 의학적 용도 |
| WO2025031285A1 (zh) * | 2023-08-04 | 2025-02-13 | 江苏恒瑞医药股份有限公司 | 抗psma抗体-药物偶联物及其医药用途 |
| TW202542201A (zh) * | 2023-12-29 | 2025-11-01 | 瑞士商Ｔ Ｏ Ａ Ｄ 腫瘤學股份有限公司 | 抗psma軛合物及其使用方法 |
| WO2026138778A1 (zh) * | 2024-12-23 | 2026-07-02 | 江苏恒瑞医药股份有限公司 | 一种包含抗c-Met抗体-药物偶联物的药物组合物及其用途 |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5208020A (en) | 1989-10-25 | 1993-05-04 | Immunogen Inc. | Cytotoxic agents comprising maytansinoids and their therapeutic use |
| US6504029B1 (en) | 1995-04-10 | 2003-01-07 | Daiichi Pharmaceutical Co., Ltd. | Condensed-hexacyclic compounds and a process therefor |
| WO2003000657A1 (en) | 2001-06-20 | 2003-01-03 | Daiichi Pharmaceutical Co., Ltd. | Diamine derivatives |
| WO2003034903A2 (en) * | 2001-10-23 | 2003-05-01 | Psma Development Company, L.L.C. | Psma antibodies and protein multimers |
| ES2605443T3 (es) | 2003-11-06 | 2017-03-14 | Seattle Genetics, Inc. | Conjugados de auristatina con anticuerpos anti-HER2 o anti-CD22 y su uso en terapia |
| AU2006262231B2 (en) * | 2005-06-20 | 2013-01-24 | Psma Development Company, Llc | PSMA antibody-drug conjugates |
| JP2015506349A (ja) | 2011-12-21 | 2015-03-02 | アルデリックス， インコーポレイテッド | 非全身性ｔｇｒ５アゴニスト |
| CN104168899B (zh) | 2012-01-13 | 2017-04-05 | 通用医疗公司 | 麻醉剂化合物及其相关的使用方法 |
| US10195288B2 (en) | 2012-10-11 | 2019-02-05 | Daiichi Sankyo Company, Limited | Antibody-drug conjugate |
| WO2015012904A2 (en) * | 2012-12-13 | 2015-01-29 | Immunomedics, Inc. | Antibody-sn-38 immunoconjugates with a cl2a linker |
| SG11201603960XA (en) | 2014-01-31 | 2016-07-28 | Daiichi Sankyo Co Ltd | Anti-her2 antibody-drug conjugate |
| US11185594B2 (en) * | 2014-04-10 | 2021-11-30 | Daiichi Sankyo Company, Limited | (Anti-HER2 antibody)-drug conjugate |
| PL3204018T3 (pl) * | 2014-10-07 | 2022-01-03 | Immunomedics, Inc. | Neoadiuwantowe zastosowanie koniugatów przeciwciało-lek |
| US10195175B2 (en) * | 2015-06-25 | 2019-02-05 | Immunomedics, Inc. | Synergistic effect of anti-Trop-2 antibody-drug conjugate in combination therapy for triple-negative breast cancer when used with microtubule inhibitors or PARP inhibitors |
| WO2017046746A1 (en) * | 2015-09-15 | 2017-03-23 | Acerta Pharma B.V. | Therapeutic combinations of a btk inhibitor and a gitr binding molecule, a 4-1bb agonist, or an ox40 agonist |
| CN117534764A (zh) * | 2016-06-06 | 2024-02-09 | 阿布泽纳(英国)有限公司 | 抗体、其用途及其缀合物 |
| CN112469440B (zh) * | 2018-06-18 | 2024-09-06 | 优瑞科生物技术公司 | 靶向前列腺特异性膜抗原(psma)的构建体和其用途 |
| UA130338C2 (uk) * | 2018-09-26 | 2026-01-28 | Джянгсу Хенгруй Медісін Ко., Лтд. | Кон'югат ліганд-лікарський засіб аналога ексатекану, спосіб його отримання та його застосування |
| CN112125915A (zh) * | 2019-09-18 | 2020-12-25 | 四川百利药业有限责任公司 | 一种喜树碱衍生物及其偶联物 |
-
2021
- 2021-03-25 MX MX2022011808A patent/MX2022011808A/es unknown
- 2021-03-25 AU AU2021240756A patent/AU2021240756A1/en active Pending
- 2021-03-25 US US17/914,209 patent/US20230140397A1/en not_active Abandoned
- 2021-03-25 TW TW110110881A patent/TWI888517B/zh active
- 2021-03-25 WO PCT/CN2021/082857 patent/WO2021190583A1/zh not_active Ceased
- 2021-03-25 CA CA3177279A patent/CA3177279A1/en active Pending
- 2021-03-25 KR KR1020227035634A patent/KR20220160016A/ko active Pending
- 2021-03-25 BR BR112022019027A patent/BR112022019027A2/pt unknown
- 2021-03-25 EP EP21775717.8A patent/EP4130006A4/en active Pending
- 2021-03-25 CN CN202180022490.3A patent/CN115298186B/zh active Active
- 2021-03-25 JP JP2022557789A patent/JP2023519261A/ja active Pending
-
2022
- 2022-09-28 ZA ZA2022/10724A patent/ZA202210724B/en unknown
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