JP2023535121A5 - - Google Patents

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Publication number
JP2023535121A5
JP2023535121A5 JP2022570440A JP2022570440A JP2023535121A5 JP 2023535121 A5 JP2023535121 A5 JP 2023535121A5 JP 2022570440 A JP2022570440 A JP 2022570440A JP 2022570440 A JP2022570440 A JP 2022570440A JP 2023535121 A5 JP2023535121 A5 JP 2023535121A5
Authority
JP
Japan
Prior art keywords
parkin
seq
optionally
protein
polynucleotide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2022570440A
Other languages
English (en)
Japanese (ja)
Other versions
JP2023535121A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2021/033491 external-priority patent/WO2021236981A2/en
Publication of JP2023535121A publication Critical patent/JP2023535121A/ja
Publication of JP2023535121A5 publication Critical patent/JP2023535121A5/ja
Pending legal-status Critical Current

Links

JP2022570440A 2020-05-20 2021-05-20 操作されたパーキン及びその使用 Pending JP2023535121A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202063027866P 2020-05-20 2020-05-20
US202063027868P 2020-05-20 2020-05-20
US63/027,868 2020-05-20
US63/027,866 2020-05-20
PCT/US2021/033491 WO2021236981A2 (en) 2020-05-20 2021-05-20 Engineered parkin and uses thereof

Publications (2)

Publication Number Publication Date
JP2023535121A JP2023535121A (ja) 2023-08-16
JP2023535121A5 true JP2023535121A5 (https=) 2024-05-29

Family

ID=78707577

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022570440A Pending JP2023535121A (ja) 2020-05-20 2021-05-20 操作されたパーキン及びその使用

Country Status (5)

Country Link
US (1) US20230174994A1 (https=)
EP (1) EP4153614A4 (https=)
JP (1) JP2023535121A (https=)
CA (1) CA3177341A1 (https=)
WO (1) WO2021236981A2 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUE055862T2 (hu) 2016-04-20 2021-12-28 Centro De Investig Energeticas Készítmények és eljárások PKLR fokozott génexpressziójára
SG11202002263TA (en) 2017-10-16 2020-04-29 Centro De Investigaciones Energeticas Medioambientales Y Tecnologicas Lentiviral vectors for delivery of pklr to treat pyruvate kinase deficiency
WO2019200167A1 (en) 2018-04-11 2019-10-17 Rocket Pharmaceuticals, Ltd. Compositions and methods for stem cell transplant
MX2020011386A (es) 2018-04-27 2021-01-29 Spacecraft Seven Llc Terapia genica para la degeneracion del snc.
KR20230043869A (ko) 2020-08-07 2023-03-31 스페이스크래프트 세븐, 엘엘씨 Aav 벡터를 사용한 플라코필린-2(pkp2) 유전자 요법
CN119193701B (zh) * 2024-09-13 2025-07-15 暨南大学 帕金森动物模型的构建方法与特异性靶向Parkin基因的gRNA及其应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009026116A2 (en) * 2007-08-16 2009-02-26 Genizon Biosciences, Inc. Genemap of the human genes associated with longevity
WO2011053825A2 (en) * 2009-10-30 2011-05-05 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Compositions and methods for the treatment or prevention of mitochondrial diseases
WO2012050402A2 (ko) * 2010-10-14 2012-04-19 주식회사 프로셀제약 세포투과성 parkin 재조합 단백질 및 이를 함유하는 퇴행성 뇌질환 치료용 약학적 조성물
US9283287B2 (en) * 2012-04-02 2016-03-15 Moderna Therapeutics, Inc. Modified polynucleotides for the production of nuclear proteins
CA3150658A1 (en) * 2013-01-18 2014-07-24 Foundation Medicine, Inc. Methods of treating cholangiocarcinoma
MX2020011386A (es) * 2018-04-27 2021-01-29 Spacecraft Seven Llc Terapia genica para la degeneracion del snc.

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