JP2023534847A5 - - Google Patents

Info

Publication number
JP2023534847A5
JP2023534847A5 JP2023504420A JP2023504420A JP2023534847A5 JP 2023534847 A5 JP2023534847 A5 JP 2023534847A5 JP 2023504420 A JP2023504420 A JP 2023504420A JP 2023504420 A JP2023504420 A JP 2023504420A JP 2023534847 A5 JP2023534847 A5 JP 2023534847A5
Authority
JP
Japan
Application number
JP2023504420A
Other languages
Japanese (ja)
Other versions
JPWO2022019945A5 (https=
JP2023534847A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2020/062907 external-priority patent/WO2022019945A1/en
Publication of JP2023534847A publication Critical patent/JP2023534847A/ja
Publication of JPWO2022019945A5 publication Critical patent/JPWO2022019945A5/ja
Publication of JP2023534847A5 publication Critical patent/JP2023534847A5/ja
Pending legal-status Critical Current

Links

JP2023504420A 2020-07-20 2020-12-02 Il-10を含む二重サイトカイン融合タンパク質 Pending JP2023534847A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202063054208P 2020-07-20 2020-07-20
US63/054,208 2020-07-20
PCT/US2020/062907 WO2022019945A1 (en) 2020-07-20 2020-12-02 Dual cytokine fusion proteins comprising il-10

Publications (3)

Publication Number Publication Date
JP2023534847A JP2023534847A (ja) 2023-08-14
JPWO2022019945A5 JPWO2022019945A5 (https=) 2023-12-11
JP2023534847A5 true JP2023534847A5 (https=) 2023-12-11

Family

ID=79291996

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023504420A Pending JP2023534847A (ja) 2020-07-20 2020-12-02 Il-10を含む二重サイトカイン融合タンパク質

Country Status (11)

Country Link
US (19) US11292822B2 (https=)
EP (1) EP4181957A4 (https=)
JP (1) JP2023534847A (https=)
KR (1) KR20230096959A (https=)
CN (1) CN116322785A (https=)
AU (1) AU2020459746A1 (https=)
BR (1) BR112023001187A2 (https=)
CA (1) CA3186753A1 (https=)
IL (1) IL300062A (https=)
MX (1) MX2023000948A (https=)
WO (1) WO2022019945A1 (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7641912B2 (ja) 2019-04-19 2025-03-07 シナーキン・ファーマ・ベスローテン・フエンノートシャップ Il13を含む融合タンパク質
CA3186753A1 (en) 2020-07-20 2022-01-27 John Mumm Dual cytokine fusion proteins comprising il-10
JP2024546999A (ja) * 2021-12-16 2024-12-26 デカ バイオサイエンシーズ, インコーポレイテッド Il-10を含む二重サイトカイン融合物およびがんを処置するための養子細胞療法または二重特異性t細胞エンゲージャー
CN118900697A (zh) * 2022-02-22 2024-11-05 德卡生物科学公司 使用白细胞介素减轻双特异性t细胞接合器或嵌合抗原受体t细胞介导的细胞因子释放综合征的方法
KR20250078792A (ko) * 2023-11-24 2025-06-04 주식회사 메드팩토 피브로넥틴 엑스트라도메인 B (Extradomain B of Fibronectin, EDB-FN) 및 전환성장인자 베타(transforming growth factor β, TGFβ)에 특이적으로 결합하는 융합 단백질 및 이의 용도
WO2025148750A1 (zh) * 2024-01-08 2025-07-17 上药生物治疗(香港)有限公司 膜表达il-10及其用途
CN119954974B (zh) * 2025-04-09 2025-07-22 四川康德赛医疗科技有限公司 一种工程化巨噬细胞,其制备方法及抗纤维化的应用

Family Cites Families (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5989867A (en) 1996-09-23 1999-11-23 Knappe; Andrea DNA encoding IL-10-like homologue; related reagents
JP4793971B2 (ja) * 1999-08-09 2011-10-12 メルク パテント ゲーエムベーハー 複合サイトカイン−抗体複合体
US8809504B2 (en) * 2002-09-03 2014-08-19 Vit Lauermann Inhibitor which is deactivatable by a reagent produced by a target cell
EA200802289A1 (ru) 2006-05-08 2009-04-28 Филоджен Спа Направляемые к мишени антителами цитокины для терапии
WO2008130382A2 (en) 2006-10-31 2008-10-30 East Carolina University Fusion proteins comprising an anti -inflammatory cytokine and an antigen for treatment of immune disorders
ES2536772T3 (es) 2007-09-21 2015-05-28 The Regents Of The University Of California El interferón dirigido demuestra potentes actividades apoptóticas y antitumorales
WO2009056268A1 (en) 2007-10-30 2009-05-07 Philogen S.P.A. An antigen associated with rheumatoid arthritis
NZ592420A (en) 2008-10-02 2012-12-21 Emergent Product Dev Seattle Cd86 antagonist multi-target binding proteins
US9249225B2 (en) * 2010-05-26 2016-02-02 Regents Of The University Of Minnesota Single chain variable fragment anti-CD133 antibodies and uses thereof
WO2012045334A1 (en) 2010-10-05 2012-04-12 Synthon Bv Biologically active il-10 fusion proteins
EA201892619A1 (ru) 2011-04-29 2019-04-30 Роше Гликарт Аг Иммуноконъюгаты, содержащие мутантные полипептиды интерлейкина-2
EP2736535B1 (en) 2011-07-27 2018-10-17 Philogen S.p.A. Il-12 immunoconjugate
KR102277469B1 (ko) 2011-12-12 2021-07-15 더 트러스티스 오브 더 유니버시티 오브 펜실바니아 개선된 il-12 유전적 컨스트럭트 및 백신을 포함하는 조성물, 면역치료제 및 이를 이용하는 방법
CN104245722A (zh) 2012-02-29 2014-12-24 Ambrx公司 白细胞介素-10多肽结合物和其用途
CA2876285A1 (en) * 2012-08-08 2014-02-13 Roche Glycart Ag Interleukin-10 fusion proteins and uses thereof
RU2612878C2 (ru) * 2012-10-03 2017-03-13 Филоджен С.П.А. Антигены, ассоциированные с воспалительным заболеванием кишечника
KR20160043927A (ko) 2013-03-14 2016-04-22 파카쉬 길 세포 표면 grp78에 결합하는 항체를 사용하는 암 치료
AU2014257906A1 (en) 2013-04-26 2015-12-10 Philogen S.P.A. IL4 conjugated to antibodies against extracellular matrix components
WO2015117930A1 (en) 2014-02-06 2015-08-13 F. Hoffmann-La Roche Ag Interleukine 10 immunoconjugates
CN106659774A (zh) 2014-05-16 2017-05-10 贝勒研究院 用于治疗自身免疫和炎性病症的方法和组合物
CN104403004B (zh) 2014-11-24 2017-10-13 苏州丁孚靶点生物技术有限公司 抗体‑干扰素异二聚体的制备和用途
AU2015364396B2 (en) 2014-12-19 2018-08-09 Alkermes, Inc. Single chain Fc fusion proteins
CA2986755A1 (en) 2015-05-28 2016-12-01 Armo Biosciences, Inc. Pegylated interleukin-10 for use in treating cancer
KR101811050B1 (ko) 2015-09-02 2017-12-21 경북대학교 산학협력단 항염증성 폴리펩티드와 페리틴 모노머 단편이 접합된 융합폴리펩티드 및 이를 유효성분으로 포함하는 염증성 질환 예방 및 치료용 약학적 조성물
WO2017091611A1 (en) 2015-11-23 2017-06-01 Immungene, Inc Enhanced cancer immunotherapy using antibody-interferon fusion molecules
UY37003A (es) 2015-12-04 2017-06-30 Novartis Ag Composiciones de anticuerpo injertado con citoquina y métodos para su uso en inmunorregulacion
CN106349393B (zh) * 2015-12-21 2020-10-30 合肥立方制药股份有限公司 一种增强抗体药物稳定性的结构
CA3044556C (en) 2016-04-12 2020-11-17 Philogen S.P.A. Combination therapy comprising an inflammatory immunocytokine and a chimeric antigen receptor (car)-t cell
KR102379464B1 (ko) 2016-06-20 2022-03-29 키맵 리미티드 항-pd-l1 항체
WO2018156791A1 (en) 2017-02-22 2018-08-30 Aleta Biotherapeutics Inc. Compositions and methods for tumor transduction
EP3625253A4 (en) * 2017-05-16 2021-03-24 Scalmibio, Inc. ACTIVABLE ANTIBODIES AND THEIR METHODS OF USE
WO2019201866A1 (en) * 2018-04-16 2019-10-24 Swedish Orphan Biovitrum Ab (Publ) Fusion protein
CA3100005A1 (en) 2018-05-14 2019-11-21 Werewolf Therapeutics, Inc. Activatable cytokine polypeptides and methods of use thereof
JP2022524018A (ja) 2019-03-06 2022-04-27 デカ バイオサイエンシーズ, インコーポレイテッド Il-10バリアント分子ならびに炎症性疾患および腫瘍を処置する方法
US20210214782A1 (en) 2020-01-09 2021-07-15 Deka Biosciences, Inc. Method of using genetic markers, single nucleotide polymorphisms and/or indels to determine responsiveness to il-10 or il-10 derivative treatment
AU2021257439A1 (en) 2020-04-13 2022-12-15 University Health Network Methods for treating cytokine release syndrome
CA3186753A1 (en) * 2020-07-20 2022-01-27 John Mumm Dual cytokine fusion proteins comprising il-10
CA3215528A1 (en) 2021-05-11 2022-11-17 Salvatore Albani Chimeric antigen receptors and modified cells comprising the same
JP2024546938A (ja) 2021-12-13 2024-12-26 デカ バイオサイエンシーズ, インコーポレイテッド マルチサブユニットサイトカインを含む二重サイトカイン融合タンパク質
JP2024546999A (ja) 2021-12-16 2024-12-26 デカ バイオサイエンシーズ, インコーポレイテッド Il-10を含む二重サイトカイン融合物およびがんを処置するための養子細胞療法または二重特異性t細胞エンゲージャー
CN118900697A (zh) 2022-02-22 2024-11-05 德卡生物科学公司 使用白细胞介素减轻双特异性t细胞接合器或嵌合抗原受体t细胞介导的细胞因子释放综合征的方法

Similar Documents

Publication Publication Date Title
CN306102337S (https=)
CN305749498S (https=)
CN305585913S (https=)
CN305616168S (https=)
CN305616330S (https=)
CN305643601S (https=)
CN305669543S (https=)
CN305670363S (https=)
CN305671976S (https=)
CN305672803S (https=)
CN305674957S (https=)
CN305675806S (https=)
CN305711803S (https=)
CN305717472S (https=)
CN305717633S (https=)
CN305719413S (https=)
CN305743859S (https=)
CN305748467S (https=)
CN306105610S (https=)
CN305753692S (https=)
CN305771682S (https=)
CN305774821S (https=)
CN305775393S (https=)
CN305775714S (https=)
CN305929348S (https=)