JP2025508882A5 - - Google Patents

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Publication number
JP2025508882A5
JP2025508882A5 JP2024550728A JP2024550728A JP2025508882A5 JP 2025508882 A5 JP2025508882 A5 JP 2025508882A5 JP 2024550728 A JP2024550728 A JP 2024550728A JP 2024550728 A JP2024550728 A JP 2024550728A JP 2025508882 A5 JP2025508882 A5 JP 2025508882A5
Authority
JP
Japan
Application number
JP2024550728A
Other languages
Japanese (ja)
Other versions
JP2025508882A (ja
JPWO2023164288A5 (https=
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2023/014128 external-priority patent/WO2023164288A2/en
Publication of JP2025508882A publication Critical patent/JP2025508882A/ja
Publication of JP2025508882A5 publication Critical patent/JP2025508882A5/ja
Publication of JPWO2023164288A5 publication Critical patent/JPWO2023164288A5/ja
Pending legal-status Critical Current

Links

JP2024550728A 2022-02-28 2023-02-28 標的化サイトカインおよびその使用方法 Pending JP2025508882A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202263314928P 2022-02-28 2022-02-28
US202263314926P 2022-02-28 2022-02-28
US63/314,926 2022-02-28
US63/314,928 2022-02-28
PCT/US2023/014128 WO2023164288A2 (en) 2022-02-28 2023-02-28 Targeted cytokines and methods of use thereof

Publications (3)

Publication Number Publication Date
JP2025508882A JP2025508882A (ja) 2025-04-10
JP2025508882A5 true JP2025508882A5 (https=) 2026-03-05
JPWO2023164288A5 JPWO2023164288A5 (https=) 2026-03-05

Family

ID=85791876

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024550728A Pending JP2025508882A (ja) 2022-02-28 2023-02-28 標的化サイトカインおよびその使用方法

Country Status (11)

Country Link
US (1) US20230365641A1 (https=)
EP (1) EP4486460A2 (https=)
JP (1) JP2025508882A (https=)
KR (1) KR20240152853A (https=)
CN (1) CN120248131A (https=)
AU (1) AU2023225803A1 (https=)
CA (1) CA3247112A1 (https=)
IL (1) IL314922A (https=)
MX (1) MX2024010488A (https=)
TW (1) TW202342504A (https=)
WO (1) WO2023164288A2 (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116554344A (zh) * 2022-01-30 2023-08-08 中国科学院生物物理研究所 一种pd1抗体与白介素2融合的双功能分子
US20250092109A1 (en) * 2023-08-30 2025-03-20 Xilio Development, Inc. Vhh masked cytokines and methods of use thereof
WO2025049948A1 (en) * 2023-08-30 2025-03-06 Xilio Development, Inc. Masked il-2 cytokines and methods of use thereof
WO2025151274A1 (en) * 2024-01-08 2025-07-17 Adimab, Llc Inducible il-18 prodrugs
TW202545979A (zh) * 2024-01-10 2025-12-01 美商艾希利歐發展股份有限公司 經遮蔽之il-2細胞介素及其使用方法
WO2025242835A1 (en) * 2024-05-22 2025-11-27 Ose Immunotherapeutics Molecules comprising masking linkers and uses thereof for the treatment of cancer
WO2025242836A1 (en) * 2024-05-22 2025-11-27 Ose Immunotherapeutics Molecules comprising masking linkers and uses thereof for the treatment of auto-immune or inflammatory diseases and disorders

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5731168A (en) 1995-03-01 1998-03-24 Genentech, Inc. Method for making heteromultimeric polypeptides
US5641870A (en) 1995-04-20 1997-06-24 Genentech, Inc. Low pH hydrophobic interaction chromatography for antibody purification
US20140302037A1 (en) 2013-03-15 2014-10-09 Amgen Inc. BISPECIFIC-Fc MOLECULES
CN120463822A (zh) * 2018-09-27 2025-08-12 西里欧发展公司 掩蔽型细胞因子多肽
US20220289822A1 (en) * 2019-08-21 2022-09-15 AskGene Pharma, Inc. Novel il-21 prodrugs and methods of use thereof
JP7735306B2 (ja) * 2020-04-01 2025-09-08 エクシリオ デベロップメント, インコーポレイテッド マスクされたil-2サイトカイン及びその切断産物
IL296911A (en) * 2020-04-01 2022-12-01 Xilio Dev Inc Masked il-15 cytokines and their cleavage products
AU2021248919A1 (en) * 2020-04-01 2022-10-13 Xilio Development, Inc. Masked IL-12 cytokines and their cleavage products
WO2022115865A2 (en) * 2020-11-25 2022-06-02 Xilio Development, Inc. Tumor-specific cleavable linkers

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