JP2023531517A5 - - Google Patents

Info

Publication number
JP2023531517A5
JP2023531517A5 JP2022579725A JP2022579725A JP2023531517A5 JP 2023531517 A5 JP2023531517 A5 JP 2023531517A5 JP 2022579725 A JP2022579725 A JP 2022579725A JP 2022579725 A JP2022579725 A JP 2022579725A JP 2023531517 A5 JP2023531517 A5 JP 2023531517A5
Authority
JP
Japan
Prior art keywords
unsubstituted
substituted
compound
pharmaceutically acceptable
acceptable salt
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2022579725A
Other languages
English (en)
Japanese (ja)
Other versions
JP2023531517A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2021/038661 external-priority patent/WO2021262836A1/en
Publication of JP2023531517A publication Critical patent/JP2023531517A/ja
Publication of JP2023531517A5 publication Critical patent/JP2023531517A5/ja
Priority to JP2026000046A priority Critical patent/JP2026042854A/ja
Pending legal-status Critical Current

Links

JP2022579725A 2020-06-24 2021-06-23 3.アルファ.-ヒドロキシ、17.ベータ.-c(o)-n-アリール置換神経活性ステロイド及びそれらの組成物 Pending JP2023531517A (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2026000046A JP2026042854A (ja) 2020-06-24 2026-01-04 3.アルファ.-ヒドロキシ、17.ベータ.-c(o)-n-アリール置換神経活性ステロイド及びそれらの組成物

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202063043641P 2020-06-24 2020-06-24
US63/043,641 2020-06-24
PCT/US2021/038661 WO2021262836A1 (en) 2020-06-24 2021-06-23 3.alpha.-hydroxy, 17.beta.-c(o)-n-aryl substituted neuroactive steroids and compositions thereof

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2026000046A Division JP2026042854A (ja) 2020-06-24 2026-01-04 3.アルファ.-ヒドロキシ、17.ベータ.-c(o)-n-アリール置換神経活性ステロイド及びそれらの組成物

Publications (2)

Publication Number Publication Date
JP2023531517A JP2023531517A (ja) 2023-07-24
JP2023531517A5 true JP2023531517A5 (https=) 2024-07-01

Family

ID=77265178

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2022579725A Pending JP2023531517A (ja) 2020-06-24 2021-06-23 3.アルファ.-ヒドロキシ、17.ベータ.-c(o)-n-アリール置換神経活性ステロイド及びそれらの組成物
JP2026000046A Pending JP2026042854A (ja) 2020-06-24 2026-01-04 3.アルファ.-ヒドロキシ、17.ベータ.-c(o)-n-アリール置換神経活性ステロイド及びそれらの組成物

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2026000046A Pending JP2026042854A (ja) 2020-06-24 2026-01-04 3.アルファ.-ヒドロキシ、17.ベータ.-c(o)-n-アリール置換神経活性ステロイド及びそれらの組成物

Country Status (11)

Country Link
US (1) US20230250129A1 (https=)
EP (1) EP4172171A1 (https=)
JP (2) JP2023531517A (https=)
CN (1) CN115768781A (https=)
AR (1) AR122733A1 (https=)
AU (1) AU2021296846A1 (https=)
CA (1) CA3183248A1 (https=)
IL (1) IL299176A (https=)
MX (3) MX2022016343A (https=)
TW (1) TW202233198A (https=)
WO (1) WO2021262836A1 (https=)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2882708A1 (en) 2012-08-21 2014-02-27 Sage Therapeutics, Inc. Methods of treating epilepsy or status epilepticus
KR102396328B1 (ko) 2013-04-17 2022-05-10 세이지 테라퓨틱스, 인크. 19-노르 c3,3-이치환된 c21-n-피라졸릴 스테로이드 및 그의 사용 방법
US10246482B2 (en) 2014-06-18 2019-04-02 Sage Therapeutics, Inc. Neuroactive steroids, compositions, and uses thereof
JOP20200195A1 (ar) 2014-09-08 2017-06-16 Sage Therapeutics Inc سترويدات وتركيبات نشطة عصبياً، واستخداماتها
WO2016082789A1 (en) 2014-11-27 2016-06-02 Sage Therapeutics, Inc. Compositions and methods for treating cns disorders
EP3504189A1 (en) 2016-08-23 2019-07-03 Sage Therapeutics, Inc. A crystalline 19-nor c3, 3-disubstituted c21-n-pyrazolyl steroid
MA51046A (fr) 2017-12-08 2021-03-17 Sage Therapeutics Inc Dérivés de 21-[4-cyano-pyrazol-1-yl]-19-nor-pregan-3. alpha-ol-20-one deutérés pour le traitement de troubles du snc
EP4321519B1 (en) 2018-10-12 2026-04-08 Sage Therapeutics, LLC Neuroactive steroids substituted in position 10 with a cyclic group for use in the treatment of cns disorders
KR20250174100A (ko) 2018-12-05 2025-12-11 세이지 테라퓨틱스, 인크. 신경활성 스테로이드 및 이의 사용 방법
EP4711377A1 (en) * 2023-05-11 2026-03-18 Shujing Biopharma Co., Ltd Steroid compound, preparation method therefor, and use thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5376645A (en) 1990-01-23 1994-12-27 University Of Kansas Derivatives of cyclodextrins exhibiting enhanced aqueous solubility and the use thereof
MA45599A (fr) * 2016-07-11 2019-05-15 Sage Therapeutics Inc Stéroïdes neuroactifs substitués en c17, c20 et c21 et leurs procédés d'utilisation
MX2020006599A (es) * 2017-12-22 2020-11-06 Sage Therapeutics Inc Composiciones y metodos para el tratamiento de trastornos en el sistema nervioso central.
EP3750909B1 (en) * 2018-02-11 2025-03-05 Jiangsu Hansoh Pharmaceutical Group Co., Ltd. Steroid derivative regulators, method for preparing the same, and uses thereof
WO2020132504A1 (en) * 2018-12-21 2020-06-25 Sage Therapeutics, Inc. 3.alpha.-hydroxy-17.beta.-amide neuroactive steroids and compositions thereof

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