MX2022016343A - Esteroides neuroactivos y composiciones de estos. - Google Patents
Esteroides neuroactivos y composiciones de estos.Info
- Publication number
- MX2022016343A MX2022016343A MX2022016343A MX2022016343A MX2022016343A MX 2022016343 A MX2022016343 A MX 2022016343A MX 2022016343 A MX2022016343 A MX 2022016343A MX 2022016343 A MX2022016343 A MX 2022016343A MX 2022016343 A MX2022016343 A MX 2022016343A
- Authority
- MX
- Mexico
- Prior art keywords
- sup
- beta
- alpha
- hydroxy
- compositions
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J63/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by expansion of only one ring by one or two atoms
- C07J63/008—Expansion of ring D by one atom, e.g. D homo steroids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0003—Androstane derivatives
- C07J1/0011—Androstane derivatives substituted in position 17 by a keto group
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J3/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom
- C07J3/005—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom the carbon atom being part of a carboxylic function
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of only two carbon atoms, e.g. pregnane derivatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0066—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by a carbon atom forming part of an amide group
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J51/00—Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
- C07J7/0005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21
- C07J7/001—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group
- C07J7/0015—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group not substituted in position 17 alfa
- C07J7/002—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group not substituted in position 17 alfa not substituted in position 16
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Addiction (AREA)
- Psychology (AREA)
- Anesthesiology (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063043641P | 2020-06-24 | 2020-06-24 | |
| PCT/US2021/038661 WO2021262836A1 (en) | 2020-06-24 | 2021-06-23 | 3.alpha.-hydroxy, 17.beta.-c(o)-n-aryl substituted neuroactive steroids and compositions thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2022016343A true MX2022016343A (es) | 2023-03-06 |
Family
ID=77265178
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2022016343A MX2022016343A (es) | 2020-06-24 | 2021-06-23 | Esteroides neuroactivos y composiciones de estos. |
| MX2024008998A MX2024008998A (es) | 2020-06-24 | 2022-12-15 | Esteroides neuroactivos y composiciones de estos. |
| MX2024008999A MX2024008999A (es) | 2020-06-24 | 2022-12-15 | Esteroides neuroactivos y composiciones de estos. |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2024008998A MX2024008998A (es) | 2020-06-24 | 2022-12-15 | Esteroides neuroactivos y composiciones de estos. |
| MX2024008999A MX2024008999A (es) | 2020-06-24 | 2022-12-15 | Esteroides neuroactivos y composiciones de estos. |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20230250129A1 (https=) |
| EP (1) | EP4172171A1 (https=) |
| JP (2) | JP2023531517A (https=) |
| CN (1) | CN115768781A (https=) |
| AR (1) | AR122733A1 (https=) |
| AU (1) | AU2021296846A1 (https=) |
| CA (1) | CA3183248A1 (https=) |
| IL (1) | IL299176A (https=) |
| MX (3) | MX2022016343A (https=) |
| TW (1) | TW202233198A (https=) |
| WO (1) | WO2021262836A1 (https=) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2882708A1 (en) | 2012-08-21 | 2014-02-27 | Sage Therapeutics, Inc. | Methods of treating epilepsy or status epilepticus |
| KR102396328B1 (ko) | 2013-04-17 | 2022-05-10 | 세이지 테라퓨틱스, 인크. | 19-노르 c3,3-이치환된 c21-n-피라졸릴 스테로이드 및 그의 사용 방법 |
| US10246482B2 (en) | 2014-06-18 | 2019-04-02 | Sage Therapeutics, Inc. | Neuroactive steroids, compositions, and uses thereof |
| JOP20200195A1 (ar) | 2014-09-08 | 2017-06-16 | Sage Therapeutics Inc | سترويدات وتركيبات نشطة عصبياً، واستخداماتها |
| WO2016082789A1 (en) | 2014-11-27 | 2016-06-02 | Sage Therapeutics, Inc. | Compositions and methods for treating cns disorders |
| EP3504189A1 (en) | 2016-08-23 | 2019-07-03 | Sage Therapeutics, Inc. | A crystalline 19-nor c3, 3-disubstituted c21-n-pyrazolyl steroid |
| MA51046A (fr) | 2017-12-08 | 2021-03-17 | Sage Therapeutics Inc | Dérivés de 21-[4-cyano-pyrazol-1-yl]-19-nor-pregan-3. alpha-ol-20-one deutérés pour le traitement de troubles du snc |
| EP4321519B1 (en) | 2018-10-12 | 2026-04-08 | Sage Therapeutics, LLC | Neuroactive steroids substituted in position 10 with a cyclic group for use in the treatment of cns disorders |
| KR20250174100A (ko) | 2018-12-05 | 2025-12-11 | 세이지 테라퓨틱스, 인크. | 신경활성 스테로이드 및 이의 사용 방법 |
| EP4711377A1 (en) * | 2023-05-11 | 2026-03-18 | Shujing Biopharma Co., Ltd | Steroid compound, preparation method therefor, and use thereof |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5376645A (en) | 1990-01-23 | 1994-12-27 | University Of Kansas | Derivatives of cyclodextrins exhibiting enhanced aqueous solubility and the use thereof |
| MA45599A (fr) * | 2016-07-11 | 2019-05-15 | Sage Therapeutics Inc | Stéroïdes neuroactifs substitués en c17, c20 et c21 et leurs procédés d'utilisation |
| MX2020006599A (es) * | 2017-12-22 | 2020-11-06 | Sage Therapeutics Inc | Composiciones y metodos para el tratamiento de trastornos en el sistema nervioso central. |
| EP3750909B1 (en) * | 2018-02-11 | 2025-03-05 | Jiangsu Hansoh Pharmaceutical Group Co., Ltd. | Steroid derivative regulators, method for preparing the same, and uses thereof |
| WO2020132504A1 (en) * | 2018-12-21 | 2020-06-25 | Sage Therapeutics, Inc. | 3.alpha.-hydroxy-17.beta.-amide neuroactive steroids and compositions thereof |
-
2021
- 2021-06-23 US US18/003,215 patent/US20230250129A1/en active Pending
- 2021-06-23 EP EP21752283.8A patent/EP4172171A1/en active Pending
- 2021-06-23 CN CN202180044419.5A patent/CN115768781A/zh active Pending
- 2021-06-23 CA CA3183248A patent/CA3183248A1/en active Pending
- 2021-06-23 WO PCT/US2021/038661 patent/WO2021262836A1/en not_active Ceased
- 2021-06-23 AU AU2021296846A patent/AU2021296846A1/en active Pending
- 2021-06-23 IL IL299176A patent/IL299176A/en unknown
- 2021-06-23 JP JP2022579725A patent/JP2023531517A/ja active Pending
- 2021-06-23 MX MX2022016343A patent/MX2022016343A/es unknown
- 2021-06-24 TW TW110123100A patent/TW202233198A/zh unknown
- 2021-06-24 AR ARP210101745A patent/AR122733A1/es unknown
-
2022
- 2022-12-15 MX MX2024008998A patent/MX2024008998A/es unknown
- 2022-12-15 MX MX2024008999A patent/MX2024008999A/es unknown
-
2026
- 2026-01-04 JP JP2026000046A patent/JP2026042854A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| AR122733A1 (es) | 2022-10-05 |
| CA3183248A1 (en) | 2021-12-30 |
| WO2021262836A1 (en) | 2021-12-30 |
| US20230250129A1 (en) | 2023-08-10 |
| MX2024008998A (es) | 2024-07-30 |
| IL299176A (en) | 2023-02-01 |
| CN115768781A (zh) | 2023-03-07 |
| MX2024008999A (es) | 2024-07-30 |
| TW202233198A (zh) | 2022-09-01 |
| AU2021296846A1 (en) | 2022-12-15 |
| JP2023531517A (ja) | 2023-07-24 |
| EP4172171A1 (en) | 2023-05-03 |
| JP2026042854A (ja) | 2026-03-11 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MX2024008998A (es) | Esteroides neuroactivos y composiciones de estos. | |
| MX2025000126A (es) | Esteroides neuroactivos alfa.-hidroxi-17.beta.-amida y composiciones de los mismos | |
| MX2024009540A (es) | Esteroides neuroactivos y composiciones de estos. | |
| MX2024004789A (es) | Esteroides neuroactivos y sus metodos de uso. | |
| MX2024011494A (es) | Esteroides neuroactivos sustituidos en la posicion 10 con un grupo ciclico para su uso en el tratamiento de trastornos del snc. | |
| MX2025008327A (es) | Composiciones y metodos para el tratamiento de trastornos del snc | |
| MX2020007633A (es) | Péptidos macrocíclicos contra acinetobacter baumannii. | |
| PE20230239A1 (es) | Derivado de arilamida con actividad antitumoral | |
| EP4606812A3 (en) | 9(11)-unsaturated neuroactive steroids and their methods of use | |
| EP4442695A3 (en) | 19-homo, 3.alpha.-hydroxy-steroid-20-one compounds for treating cns disorders | |
| NO20062905L (no) | Nye hydroksaminsyreestere og farmasoytisk anvendelse derav | |
| NO20062370L (no) | Amidderivater | |
| JP2010523684A (ja) | テトラサイクリン化合物を用いる、脊髄筋委縮症を治療するための方法 | |
| MX2022004450A (es) | Aminas de heteroaril-bifenilo para el tratamiento de enfermedades pd-l1. | |
| EP4360707A3 (en) | Compositions for treating spinal muscular atrophy | |
| NO20085077L (no) | Nye forbindelser | |
| NO20070576L (no) | Nye hydantionderivater for behandling av obstruktive luftveissykdommer. | |
| NO20073730L (no) | Amidderivater | |
| MX2010007375A (es) | Nuevos derivados de lupano. | |
| RU2011136250A (ru) | Низкомолекулярное полисульфатированное производное гиалуроновой кислоты и содержащее его лекарственное средство | |
| KR950032267A (ko) | 11,21-비스페닐-19-노르프레그난 유도체 | |
| NO20071321L (no) | Anti-inflammatoriske midler | |
| CA3200722A1 (en) | Heteroaryl-acetylenes, pharmaceutical compositions thereof, and their therapeutic applications | |
| FR2850023B1 (fr) | Medicaments pour le systeme nerveux | |
| WO2012137224A1 (en) | Coumarin compounds for the treatment of mycobacterial infections |