JP2023531496A5 - - Google Patents

Info

Publication number
JP2023531496A5
JP2023531496A5 JP2022579000A JP2022579000A JP2023531496A5 JP 2023531496 A5 JP2023531496 A5 JP 2023531496A5 JP 2022579000 A JP2022579000 A JP 2022579000A JP 2022579000 A JP2022579000 A JP 2022579000A JP 2023531496 A5 JP2023531496 A5 JP 2023531496A5
Authority
JP
Japan
Prior art keywords
fusion protein
protein according
terminus
recombinant polypeptide
cytokine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2022579000A
Other languages
English (en)
Japanese (ja)
Other versions
JP2023531496A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2021/038909 external-priority patent/WO2021262985A1/en
Publication of JP2023531496A publication Critical patent/JP2023531496A/ja
Publication of JP2023531496A5 publication Critical patent/JP2023531496A5/ja
Pending legal-status Critical Current

Links

JP2022579000A 2020-06-25 2021-06-24 サイトカインコンジュゲート Pending JP2023531496A (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US202063044335P 2020-06-25 2020-06-25
US63/044,335 2020-06-25
US202163197875P 2021-06-07 2021-06-07
US202163197944P 2021-06-07 2021-06-07
US63/197,944 2021-06-07
US63/197,875 2021-06-07
PCT/US2021/038909 WO2021262985A1 (en) 2020-06-25 2021-06-24 Cytokine conjugates

Publications (2)

Publication Number Publication Date
JP2023531496A JP2023531496A (ja) 2023-07-24
JP2023531496A5 true JP2023531496A5 (https=) 2024-07-02

Family

ID=79281847

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022579000A Pending JP2023531496A (ja) 2020-06-25 2021-06-24 サイトカインコンジュゲート

Country Status (13)

Country Link
US (1) US20230265146A1 (https=)
EP (1) EP4171609A4 (https=)
JP (1) JP2023531496A (https=)
KR (1) KR20230042014A (https=)
CN (1) CN116096730A (https=)
AU (1) AU2021296605A1 (https=)
BR (1) BR112022026248A2 (https=)
CA (1) CA3180251A1 (https=)
CO (1) CO2023000048A2 (https=)
IL (1) IL298626A (https=)
MX (1) MX2022016389A (https=)
PH (1) PH12022553408A1 (https=)
WO (1) WO2021262985A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20250114489A1 (en) * 2022-02-15 2025-04-10 Tagworks Pharmaceuticals B.V. Masked il12 protein
IL320318A (en) * 2022-10-19 2025-06-01 Kalivir Immunotherapeutics Inc Nucleic acids encoding tgf-beta inhibitor and il-12 and uses thereof
WO2025122957A1 (en) 2023-12-08 2025-06-12 Amunix Pharmaceuticals, Inc. Protease activatable cytokines and methods for making and using the same

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020077276A1 (en) * 1999-04-27 2002-06-20 Fredeking Terry M. Compositions and methods for treating hemorrhagic virus infections and other disorders
ES2610356T3 (es) * 2009-02-03 2017-04-27 Amunix Operating Inc. Polipéptidos recombinantes extendidos y composiciones que comprenden los mismos
US8557961B2 (en) * 2010-04-02 2013-10-15 Amunix Operating Inc. Alpha 1-antitrypsin compositions and methods of making and using same
JP6355563B2 (ja) * 2012-02-27 2018-07-11 アムニクス オペレーティング インコーポレイテッド Xten共役組成物およびそれを製造する方法
IL319047A (en) * 2015-08-28 2025-04-01 Amunix Operating Inc Chimeric polypeptide composition and methods for its preparation and use
JP7285220B2 (ja) * 2017-05-18 2023-06-01 モデルナティエックス インコーポレイテッド 連結したインターロイキン-12(il12)ポリペプチドをコードするポリヌクレオチドを含む脂質ナノ粒子
AU2018393111B2 (en) * 2017-12-21 2025-07-10 Amunix Pharmaceuticals, Inc. Release segments and binding compositions comprising same
PE20210313A1 (es) * 2018-03-28 2021-02-12 Bristol Myers Squibb Co Proteinas de fusion interleucina-2/receptor alfa de interleucina-2 y metodos de uso
WO2019222296A1 (en) * 2018-05-14 2019-11-21 Werewolf Therapeutics, Inc. Activatable interleukin 12 polypeptides and methods of use thereof
EP3849592A4 (en) * 2018-08-23 2022-08-24 Exalt Therapeutics, LLC MODIFIED IFNL3 POLYPEPTIDES COMPRISING A PHARMACOKINETIC ENHANCING FRAGMENT AND THEIR USES

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