JP2023531008A5 - - Google Patents

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Publication number
JP2023531008A5
JP2023531008A5 JP2022578713A JP2022578713A JP2023531008A5 JP 2023531008 A5 JP2023531008 A5 JP 2023531008A5 JP 2022578713 A JP2022578713 A JP 2022578713A JP 2022578713 A JP2022578713 A JP 2022578713A JP 2023531008 A5 JP2023531008 A5 JP 2023531008A5
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JP
Japan
Prior art keywords
disease
disorder
abnormality
pharmaceutically acceptable
pharmaceutical product
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2022578713A
Other languages
English (en)
Japanese (ja)
Other versions
JP2023531008A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/EP2021/066695 external-priority patent/WO2021255279A1/en
Publication of JP2023531008A publication Critical patent/JP2023531008A/ja
Publication of JP2023531008A5 publication Critical patent/JP2023531008A5/ja
Pending legal-status Critical Current

Links

JP2022578713A 2020-06-19 2021-06-18 Nlrp3インフラマソーム経路を調節するジヒドロオキサゾール及びチオ尿素または尿素誘導体 Pending JP2023531008A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP20181221.1 2020-06-19
EP20181221 2020-06-19
EP21164097 2021-03-22
EP21164097.4 2021-03-22
PCT/EP2021/066695 WO2021255279A1 (en) 2020-06-19 2021-06-18 D i h yd rooxazo le and thiourea derivatives modulating the nlrp3 inflammasome pathway

Publications (2)

Publication Number Publication Date
JP2023531008A JP2023531008A (ja) 2023-07-20
JP2023531008A5 true JP2023531008A5 (https=) 2024-06-25

Family

ID=76532220

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022578713A Pending JP2023531008A (ja) 2020-06-19 2021-06-18 Nlrp3インフラマソーム経路を調節するジヒドロオキサゾール及びチオ尿素または尿素誘導体

Country Status (11)

Country Link
US (1) US20230250070A1 (https=)
EP (1) EP4168395B1 (https=)
JP (1) JP2023531008A (https=)
KR (1) KR20230028425A (https=)
CN (1) CN115768754B (https=)
AU (1) AU2021291065B2 (https=)
BR (1) BR112022025612A2 (https=)
CA (1) CA3178361A1 (https=)
IL (1) IL299084A (https=)
MX (1) MX2022014709A (https=)
WO (1) WO2021255279A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3823974A1 (en) 2018-07-20 2021-05-26 F. Hoffmann-La Roche AG Sulfonimidamide compounds as inhibitors of interleukin-1 activity
CN118541366A (zh) * 2021-12-22 2024-08-23 Ac免疫有限公司 二氢噁唑衍生物化合物
WO2025153532A1 (en) 2024-01-16 2025-07-24 NodThera Limited Nlrp3 inhibitors and glp-1 agonists combination therapies

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AU723895B2 (en) 1997-01-29 2000-09-07 Pfizer Inc. Sulfonyl urea derivatives and their use in the control of interleukin-1 activity
KR102727059B1 (ko) * 2015-02-16 2024-11-05 더 유니버서티 어브 퀸슬랜드 설포닐우레아와 관련 화합물 및 그 용도
CN109071454B (zh) 2016-02-16 2023-02-17 昆士兰大学 磺酰脲和相关化合物及其用途
ES2940611T3 (es) 2016-04-18 2023-05-09 Novartis Ag Compuestos y composiciones para el tratamiento de afecciones asociadas a la actividad de NLRP
US11597706B2 (en) 2016-04-18 2023-03-07 Novartis Ag Compounds and compositions for treating conditions associated with NLRP activity
EP3272739A1 (en) 2016-07-20 2018-01-24 NodThera Limited Sulfonyl urea derivatives and their use in the control of interleukin-1 activity
CA3047336A1 (en) 2017-01-23 2018-07-26 Jecure Therapeutics, Inc. Chemical compounds as inhibitors of interleukin-1 activity
GB2561540A (en) * 2017-03-13 2018-10-24 Nodthera Ltd Chemical compounds
AU2017416068A1 (en) 2017-05-24 2019-10-31 The Provost, Fellows, Foundation Scholars, And Other Members Of Board, Of The College Of The Holy And Undivided Trinity Of Queen Elizabeth Near Dublin Novel compounds and uses
EP3634951B8 (en) 2017-06-09 2024-08-21 Zydus Lifesciences Limited Novel substituted sulfoximine compounds
US11465992B2 (en) 2017-07-07 2022-10-11 Inflazome Limited Sulfonamide carboxamide compounds
US11370776B2 (en) 2017-07-07 2022-06-28 Inflazome Limited Sulfonylureas and sulfonylthioureas as NLRP3 inhibitors
CN111094242B (zh) 2017-07-24 2024-02-09 诺华股份有限公司 用于治疗与nlrp活性相关的病症的化合物和组合物
RS65492B1 (sr) 2017-07-24 2024-05-31 Novartis Ag Jedinjenja i kompozicije za lečenje stanja povezanih sa aktivnošću nlrp
WO2019034693A1 (en) 2017-08-15 2019-02-21 Inflazome Limited SULFONYLURATES AND SULFONYLTHIOURES AS INHIBITORS OF NLRP3
MX2020001776A (es) 2017-08-15 2020-03-24 Inflazome Ltd Sulfonilureas y sulfoniltioureas como inhibidores de nlrp3.
EP3668862A1 (en) 2017-08-15 2020-06-24 Inflazome Limited Novel sulfonamide carboxamide compounds
US11542255B2 (en) 2017-08-15 2023-01-03 Inflazome Limited Sulfonylureas and sulfonylthioureas as NLRP3 inhibitors
EP3668861A1 (en) 2017-08-15 2020-06-24 Inflazome Limited Novel sulfonamide carboxamide compounds
JP2020531448A (ja) 2017-08-15 2020-11-05 インフレイゾーム リミテッド 新規なスルホンアミドカルボキサミド化合物
US11518739B2 (en) 2017-08-15 2022-12-06 Inflazome Limited Sulfonamide carboxamide compounds
WO2019043610A1 (en) 2017-08-31 2019-03-07 Cadila Healthcare Limited NEW SUBSTITUTED SULFONYLUREA DERIVATIVES
US11623922B2 (en) 2017-10-03 2023-04-11 Inflazome Limited Compounds
EP3697758B1 (en) 2017-10-17 2022-07-06 Novartis AG Sulphonamides and compositions thereof for treating conditions associated with nlrp activity
US12221434B2 (en) 2017-11-09 2025-02-11 Inflazome Limited Sulfonamide carboxamide compounds
KR20200087759A (ko) 2017-11-09 2020-07-21 인플라좀 리미티드 신규한 설폰아마이드 카복스아마이드 화합물
WO2019092172A1 (en) 2017-11-09 2019-05-16 Inflazome Limited Novel sulfonamide carboxamide compounds
CR20200588A (es) * 2018-05-04 2021-06-24 Inflazome Ltd Compuestos novedosos
SG11202012159TA (en) 2018-07-20 2021-01-28 Hoffmann La Roche Sulfonylurea compounds as inhibitors of interleukin-1 activity
EP3823974A1 (en) 2018-07-20 2021-05-26 F. Hoffmann-La Roche AG Sulfonimidamide compounds as inhibitors of interleukin-1 activity
KR20210038877A (ko) 2018-07-25 2021-04-08 노파르티스 아게 Nlrp3 인플라마좀 억제제
WO2020157069A1 (en) * 2019-01-28 2020-08-06 NodThera Limited Amino heterocyclic compounds and uses thereof
JP2022547882A (ja) 2019-09-06 2022-11-16 インフレイゾーム リミテッド Nlrp3阻害剤

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