JP2023530778A5 - - Google Patents
Info
- Publication number
- JP2023530778A5 JP2023530778A5 JP2023502874A JP2023502874A JP2023530778A5 JP 2023530778 A5 JP2023530778 A5 JP 2023530778A5 JP 2023502874 A JP2023502874 A JP 2023502874A JP 2023502874 A JP2023502874 A JP 2023502874A JP 2023530778 A5 JP2023530778 A5 JP 2023530778A5
- Authority
- JP
- Japan
- Prior art keywords
- item
- compound
- alkyl
- salt
- independently selected
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2024218609A JP7645431B2 (ja) | 2020-03-27 | 2024-12-13 | Ｍｔｏｒｃ１モジュレーターおよびその使用 |
Applications Claiming Priority (15)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063001177P | 2020-03-27 | 2020-03-27 | |
| US202063001144P | 2020-03-27 | 2020-03-27 | |
| US202063001187P | 2020-03-27 | 2020-03-27 | |
| US63/001,177 | 2020-03-27 | ||
| US63/001,144 | 2020-03-27 | ||
| US63/001,187 | 2020-03-27 | ||
| US202063019176P | 2020-05-01 | 2020-05-01 | |
| US63/019,176 | 2020-05-01 | ||
| US202063054762P | 2020-07-21 | 2020-07-21 | |
| US202063054768P | 2020-07-21 | 2020-07-21 | |
| US202063054763P | 2020-07-21 | 2020-07-21 | |
| US63/054,762 | 2020-07-21 | ||
| US63/054,768 | 2020-07-21 | ||
| US63/054,763 | 2020-07-21 | ||
| PCT/US2021/024536 WO2021195599A1 (en) | 2020-03-27 | 2021-03-26 | Mtorc1 modulators and uses thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024218609A Division JP7645431B2 (ja) | 2020-03-27 | 2024-12-13 | Ｍｔｏｒｃ１モジュレーターおよびその使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023530778A JP2023530778A (ja) | 2023-07-19 |
| JP2023530778A5 true JP2023530778A5 (enExample) | 2024-04-04 |
| JP7606591B2 JP7606591B2 (ja) | 2024-12-25 |
Family
ID=77892684
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023502874A Active JP7606591B2 (ja) | 2020-03-27 | 2021-03-26 | Ｍｔｏｒｃ１モジュレーターおよびその使用 |
| JP2024218609A Active JP7645431B2 (ja) | 2020-03-27 | 2024-12-13 | Ｍｔｏｒｃ１モジュレーターおよびその使用 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024218609A Active JP7645431B2 (ja) | 2020-03-27 | 2024-12-13 | Ｍｔｏｒｃ１モジュレーターおよびその使用 |
Country Status (11)
| Country | Link |
|---|---|
| US (3) | US11634432B2 (enExample) |
| EP (1) | EP4126229A4 (enExample) |
| JP (2) | JP7606591B2 (enExample) |
| KR (2) | KR102805250B1 (enExample) |
| CN (2) | CN115776907B (enExample) |
| AU (2) | AU2021241718B2 (enExample) |
| CA (1) | CA3173722A1 (enExample) |
| IL (1) | IL296828A (enExample) |
| MX (1) | MX2022011964A (enExample) |
| WO (1) | WO2021195599A1 (enExample) |
| ZA (1) | ZA202210888B (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10980784B2 (en) | 2018-06-15 | 2021-04-20 | Navitor Pharmaceuticals, Inc. | Rapamycin analogs and uses thereof |
| CA3127448C (en) | 2019-01-22 | 2024-06-04 | Aeovian Pharmaceuticals, Inc. | Mtorc modulators and uses thereof |
| EP4069223A4 (en) | 2019-12-05 | 2023-12-20 | Janssen Pharmaceutica NV | RAPAMYCIN ANALOGS AND THEIR USES |
| CN115776907B (zh) | 2020-03-27 | 2025-02-25 | 艾奥维安制药公司 | Mtorc1调节剂及其用途 |
| CN121426814A (zh) * | 2020-07-21 | 2026-01-30 | 艾奥维安制药公司 | Mtorc1调节剂及其用途 |
| WO2024211738A1 (en) * | 2023-04-07 | 2024-10-10 | Regeneron Pharmaceuticals, Inc. | Selective rapamycin analogs and uses thereof |
Family Cites Families (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA935112B (en) | 1992-07-17 | 1994-02-08 | Smithkline Beecham Corp | Rapamycin derivatives |
| US5258389A (en) * | 1992-11-09 | 1993-11-02 | Merck & Co., Inc. | O-aryl, O-alkyl, O-alkenyl and O-alkynylrapamycin derivatives |
| BR9408323A (pt) | 1993-12-17 | 1997-08-19 | Sandoz Ag | Derivados de rapamicina |
| US6187757B1 (en) * | 1995-06-07 | 2001-02-13 | Ariad Pharmaceuticals, Inc. | Regulation of biological events using novel compounds |
| WO1999036553A2 (en) * | 1998-01-15 | 1999-07-22 | Ariad Gene Therapeutics, Inc. | Regulation of biological events using multimeric chimeric proteins |
| IL147803A0 (en) * | 1999-08-24 | 2002-08-14 | Ariad Gene Therapeutics Inc | 28-epirapalogs |
| EP1896075A2 (en) | 2005-06-22 | 2008-03-12 | LifeCycle Pharma A/S | Pharmaceutical compositions comprising tacrolimus and a cyp3a4 inhibitor |
| GB0601406D0 (en) * | 2006-01-24 | 2006-03-08 | Novartis Ag | Organic Compounds |
| WO2009131631A1 (en) | 2008-04-14 | 2009-10-29 | Poniard Pharmaceuticals, Inc. | Rapamycin analogs as anti-cancer agents |
| CN103391780B (zh) * | 2011-02-16 | 2015-08-19 | 诺瓦提斯公司 | 用于治疗神经变性疾病的治疗剂的组合物 |
| WO2014153118A1 (en) * | 2013-03-14 | 2014-09-25 | The Board Of Trustees Of The Leland Stanford Junior University | Treatment of diseases and conditions associated with dysregulation of mammalian target of rapamycin complex 1 (mtorc1) |
| WO2015142661A1 (en) * | 2014-03-15 | 2015-09-24 | Novartis Ag | Regulatable chimeric antigen receptor |
| EP3193902A4 (en) | 2014-09-11 | 2018-03-28 | The Regents of The University of California | mTORC1 INHIBITORS |
| US20190022073A1 (en) | 2015-09-03 | 2019-01-24 | Nippon Kayaku Kabushiki Kaisha | Pharmaceutical composition comprising rapamycin or derivative thereof |
| US10683308B2 (en) * | 2015-09-11 | 2020-06-16 | Navitor Pharmaceuticals, Inc. | Rapamycin analogs and uses thereof |
| CN108926533B (zh) | 2017-05-24 | 2022-03-25 | 江苏天士力帝益药业有限公司 | 一种替西罗莫司脂质体及其制备方法 |
| US10478561B2 (en) | 2017-08-03 | 2019-11-19 | Minhong Yu | Wireless transmission system with integrated sensing capability |
| UY37900A (es) * | 2017-09-26 | 2019-04-30 | Novartis Ag | Nuevos derivados de rapamicina |
| US10980784B2 (en) * | 2018-06-15 | 2021-04-20 | Navitor Pharmaceuticals, Inc. | Rapamycin analogs and uses thereof |
| WO2020076738A2 (en) | 2018-10-12 | 2020-04-16 | Bellicum Pharmaceuticals, Inc | Protein-binding compounds |
| LT3898637T (lt) | 2018-12-18 | 2025-03-10 | Novartis Ag | Rapamicino dariniai |
| CA3127448C (en) | 2019-01-22 | 2024-06-04 | Aeovian Pharmaceuticals, Inc. | Mtorc modulators and uses thereof |
| EP4069223A4 (en) | 2019-12-05 | 2023-12-20 | Janssen Pharmaceutica NV | RAPAMYCIN ANALOGS AND THEIR USES |
| CN115776907B (zh) | 2020-03-27 | 2025-02-25 | 艾奥维安制药公司 | Mtorc1调节剂及其用途 |
| CN121426814A (zh) | 2020-07-21 | 2026-01-30 | 艾奥维安制药公司 | Mtorc1调节剂及其用途 |
| JP2024503898A (ja) | 2021-01-22 | 2024-01-29 | ヤンセン ファーマシューティカ エヌ．ベー． | ラパマイシン類似体及びその使用 |
-
2021
- 2021-03-26 CN CN202180038254.0A patent/CN115776907B/zh active Active
- 2021-03-26 CA CA3173722A patent/CA3173722A1/en active Pending
- 2021-03-26 IL IL296828A patent/IL296828A/en unknown
- 2021-03-26 KR KR1020227036354A patent/KR102805250B1/ko active Active
- 2021-03-26 CN CN202510123209.5A patent/CN119954829A/zh active Pending
- 2021-03-26 WO PCT/US2021/024536 patent/WO2021195599A1/en not_active Ceased
- 2021-03-26 JP JP2023502874A patent/JP7606591B2/ja active Active
- 2021-03-26 AU AU2021241718A patent/AU2021241718B2/en active Active
- 2021-03-26 EP EP21775952.1A patent/EP4126229A4/en active Pending
- 2021-03-26 MX MX2022011964A patent/MX2022011964A/es unknown
- 2021-03-26 KR KR1020257014654A patent/KR102963519B1/ko active Active
-
2022
- 2022-03-01 US US17/683,549 patent/US11634432B2/en active Active
- 2022-06-03 US US17/832,240 patent/US11603377B2/en active Active
- 2022-10-03 ZA ZA2022/10888A patent/ZA202210888B/en unknown
-
2023
- 2023-03-08 US US18/180,517 patent/US20240002399A1/en active Pending
-
2024
- 2024-12-13 JP JP2024218609A patent/JP7645431B2/ja active Active
-
2025
- 2025-06-25 AU AU2025204768A patent/AU2025204768C1/en active Active
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