JP2023530704A5 - - Google Patents

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Publication number
JP2023530704A5
JP2023530704A5 JP2022577426A JP2022577426A JP2023530704A5 JP 2023530704 A5 JP2023530704 A5 JP 2023530704A5 JP 2022577426 A JP2022577426 A JP 2022577426A JP 2022577426 A JP2022577426 A JP 2022577426A JP 2023530704 A5 JP2023530704 A5 JP 2023530704A5
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JP
Japan
Prior art keywords
derived
car
cells
receptor
ipsc
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2022577426A
Other languages
English (en)
Japanese (ja)
Other versions
JP2023530704A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2021/038134 external-priority patent/WO2021258016A1/en
Publication of JP2023530704A publication Critical patent/JP2023530704A/ja
Publication of JP2023530704A5 publication Critical patent/JP2023530704A5/ja
Priority to JP2026002868A priority Critical patent/JP2026081256A/ja
Pending legal-status Critical Current

Links

JP2022577426A 2020-06-19 2021-06-18 免疫療法で使用するためのiPSC由来エフェクター細胞型の組み合わせ Pending JP2023530704A (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2026002868A JP2026081256A (ja) 2020-06-19 2026-01-09 免疫療法で使用するためのiPSC由来エフェクター細胞型の組み合わせ

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202063041672P 2020-06-19 2020-06-19
US63/041,672 2020-06-19
PCT/US2021/038134 WO2021258016A1 (en) 2020-06-19 2021-06-18 Combining ipsc-derived effector cell types for immunotherapy use

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2026002868A Division JP2026081256A (ja) 2020-06-19 2026-01-09 免疫療法で使用するためのiPSC由来エフェクター細胞型の組み合わせ

Publications (2)

Publication Number Publication Date
JP2023530704A JP2023530704A (ja) 2023-07-19
JP2023530704A5 true JP2023530704A5 (enExample) 2024-06-25

Family

ID=79025356

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2022577426A Pending JP2023530704A (ja) 2020-06-19 2021-06-18 免疫療法で使用するためのiPSC由来エフェクター細胞型の組み合わせ
JP2026002868A Pending JP2026081256A (ja) 2020-06-19 2026-01-09 免疫療法で使用するためのiPSC由来エフェクター細胞型の組み合わせ

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2026002868A Pending JP2026081256A (ja) 2020-06-19 2026-01-09 免疫療法で使用するためのiPSC由来エフェクター細胞型の組み合わせ

Country Status (11)

Country Link
US (2) US12275955B2 (enExample)
EP (1) EP4168538B1 (enExample)
JP (2) JP2023530704A (enExample)
KR (1) KR20230040337A (enExample)
CN (1) CN116096386A (enExample)
AU (1) AU2021292695A1 (enExample)
BR (1) BR112022025806A2 (enExample)
CA (1) CA3182852A1 (enExample)
IL (1) IL299106B2 (enExample)
MX (1) MX2022015863A (enExample)
WO (1) WO2021258016A1 (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL303269A (en) 2020-12-03 2023-07-01 Century Therapeutics Inc Genetically engineered cells and uses thereof
US11661459B2 (en) 2020-12-03 2023-05-30 Century Therapeutics, Inc. Artificial cell death polypeptide for chimeric antigen receptor and uses thereof
TW202241935A (zh) * 2020-12-18 2022-11-01 美商世紀治療股份有限公司 具有可調適受體專一性之嵌合抗原受體系統
WO2023129937A1 (en) * 2021-12-29 2023-07-06 Century Therapeutics, Inc. Genetically engineered cells having anti-cd19 / anti-cd22 chimeric antigen receptors, and uses thereof
EP4508193A4 (en) * 2022-04-11 2026-04-29 In8Bio Inc IPSC-BASED GAMMA-DELTA T LYMPHOCYTES: COMPOSITIONS AND METHODS OF USE
CN116948012B (zh) * 2022-04-13 2024-07-26 星奕昂(上海)生物科技有限公司 增强细胞功能的cd16抗剪切突变体
US20250090582A1 (en) * 2022-06-08 2025-03-20 Century Therapeutics, Inc. Genetically engineered cells having anti-cd133 / anti-egfr chimeric antigen receptors, and uses thereof
EP4663762A4 (en) * 2023-03-02 2026-07-29 Hongkong Bioheng Biotech Ltd TRANSFORMED CELL RESISTANT TO IMMUNE REJECTION
CN117305241B (zh) * 2023-11-28 2024-03-19 上海兴瑞一达生物科技有限公司 一种hiPSCs诱导分化为NK细胞的方法
CN118389421A (zh) * 2024-04-01 2024-07-26 苏州艾凯利元生物科技有限公司 一种体外评估nk细胞群的特性的方法
WO2026073244A1 (en) * 2024-09-30 2026-04-02 Ensoma, Inc. Constructs for multi-lineage expression of therapeutic agents

Family Cites Families (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6352694B1 (en) 1994-06-03 2002-03-05 Genetics Institute, Inc. Methods for inducing a population of T cells to proliferate using agents which recognize TCR/CD3 and ligands which stimulate an accessory molecule on the surface of the T cells
GB9710807D0 (en) 1997-05-23 1997-07-23 Medical Res Council Nucleic acid binding proteins
GB9710809D0 (en) 1997-05-23 1997-07-23 Medical Res Council Nucleic acid binding proteins
US6140081A (en) 1998-10-16 2000-10-31 The Scripps Research Institute Zinc finger binding domains for GNN
US6534261B1 (en) 1999-01-12 2003-03-18 Sangamo Biosciences, Inc. Regulation of endogenous gene expression in cells using zinc finger proteins
US6453242B1 (en) 1999-01-12 2002-09-17 Sangamo Biosciences, Inc. Selection of sites for targeting by zinc finger proteins and methods of designing zinc finger proteins to bind to preselected sites
JP2002060786A (ja) 2000-08-23 2002-02-26 Kao Corp 硬質表面用殺菌防汚剤
US20040224385A1 (en) 2001-08-20 2004-11-11 Barbas Carlos F Zinc finger binding domains for cnn
US7745140B2 (en) 2002-01-03 2010-06-29 The Trustees Of The University Of Pennsylvania Activation and expansion of T-cells using an engineered multivalent signaling platform as a research tool
US7888121B2 (en) 2003-08-08 2011-02-15 Sangamo Biosciences, Inc. Methods and compositions for targeted cleavage and recombination
US7972854B2 (en) 2004-02-05 2011-07-05 Sangamo Biosciences, Inc. Methods and compositions for targeted cleavage and recombination
AU2005250408B2 (en) 2004-05-27 2010-09-23 The Trustees Of The University Of Pennsylvania Novel artificial antigen presenting cells and uses therefor
CN105837690A (zh) 2006-06-12 2016-08-10 新兴产品开发西雅图有限公司 具有效应功能的单链多价结合蛋白
PT2816112T (pt) 2009-12-10 2018-11-20 Univ Iowa State Res Found Inc Modificação do adn modificada pelo efector tal
WO2011159726A2 (en) 2010-06-14 2011-12-22 The Scripps Research Institute Reprogramming of cells to a new fate
MX2014001222A (es) 2011-07-29 2014-09-15 Univ Pennsylvania Receptores coestimuladores de cambio.
EP2814846B1 (en) 2012-02-13 2020-01-08 Seattle Children's Hospital d/b/a Seattle Children's Research Institute Bispecific chimeric antigen receptors and therapeutic uses thereof
SG10201806573TA (en) 2012-05-25 2018-09-27 Cellectis Methods for engineering allogeneic and immunosuppressive resistant t cell for immunotherapy
IL305629A (en) 2013-02-15 2023-11-01 Univ California Chimeric antigen receptor and methods of using it
EP3789487A1 (en) * 2013-04-03 2021-03-10 Memorial Sloan Kettering Cancer Center Effective generation of tumor-targeted t-cells derived from pluripotent stem cells
US9932607B2 (en) 2013-11-15 2018-04-03 The Board Of Trustees Of The Leland Stanford Junior University Site-specific integration of transgenes into human cells
EP3104866A4 (en) 2014-02-14 2017-08-02 Bellicum Pharmaceuticals, Inc. Methods for activating t cells using an inducible chimeric polypeptide
DK3105335T3 (da) 2014-02-14 2020-01-13 Univ Texas Kimære antigenreceptorer og fremgangsmåder til fremstilling heraf
CN120536341A (zh) 2014-03-04 2025-08-26 菲特治疗公司 改良的重编程方法和细胞培养平台
CN113699159A (zh) 2014-03-28 2021-11-26 明尼苏达大学评议会 涉及经工程改造的cd16的多肽、细胞和方法
AU2015312117A1 (en) 2014-09-02 2017-03-02 Bellicum Pharmaceuticals, Inc. Costimulation of chimeric antigen receptors by Myd88 and CD40 polypeptides
CN117737124A (zh) 2015-10-16 2024-03-22 菲特治疗公司 用于诱导和维护基态多能性的平台
US12642852B1 (en) * 2015-11-04 2026-06-02 Fate Therapeutics, Inc. Genomic engineering of pluripotent cells
CN122146606A (zh) 2015-11-04 2026-06-05 菲特治疗公司 用于诱导造血细胞分化的方法和组合物
CA3007473A1 (en) 2015-12-14 2017-06-22 Bellicum Pharmaceuticals, Inc. Dual controls for therapeutic cell activation or elimination
JP7653759B2 (ja) 2016-01-20 2025-03-31 フェイト セラピューティクス,インコーポレイテッド 養子免疫療法における免疫細胞調節のための組成物および方法
US12247226B2 (en) 2017-10-11 2025-03-11 Fate Therapeutics, Inc. Cellular reprogramming using temporal and transient plasmid vector expression system
CN111556892A (zh) * 2017-12-08 2020-08-18 菲特治疗公司 使用增强的iPSC衍生的效应细胞的免疫疗法
BR112020011017A2 (pt) * 2017-12-22 2020-11-17 Fate Therapeutics, Inc. células efetoras imunes intensificadas e uso das mesmas
AU2019243315A1 (en) * 2018-03-29 2020-09-24 Fate Therapeutics, Inc. Engineered immune effector cells and use thereof
JP2022510207A (ja) * 2018-12-02 2022-01-26 フェイト セラピューティクス,インコーポレイテッド 増強されたiPSC派生エフェクター細胞を使用した免疫療法
CN113906133A (zh) 2019-04-11 2022-01-07 菲特治疗公司 工程改造的iPSC和免疫效应细胞中的CD3重建

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