JP2022541441A5 - - Google Patents
Info
- Publication number
- JP2022541441A5 JP2022541441A5 JP2022502275A JP2022502275A JP2022541441A5 JP 2022541441 A5 JP2022541441 A5 JP 2022541441A5 JP 2022502275 A JP2022502275 A JP 2022502275A JP 2022502275 A JP2022502275 A JP 2022502275A JP 2022541441 A5 JP2022541441 A5 JP 2022541441A5
- Authority
- JP
- Japan
- Prior art keywords
- cells
- derived
- cell
- car
- mica
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2025109951A JP2025157281A (ja) | 2019-07-17 | 2025-06-30 | 免疫エフェクター細胞操作およびその使用 |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962875490P | 2019-07-17 | 2019-07-17 | |
| US62/875,490 | 2019-07-17 | ||
| US202063021560P | 2020-05-07 | 2020-05-07 | |
| US63/021,560 | 2020-05-07 | ||
| PCT/US2020/042657 WO2021011919A1 (en) | 2019-07-17 | 2020-07-17 | Immune effector cell engineering and use thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025109951A Division JP2025157281A (ja) | 2019-07-17 | 2025-06-30 | 免疫エフェクター細胞操作およびその使用 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2022541441A JP2022541441A (ja) | 2022-09-26 |
| JP2022541441A5 true JP2022541441A5 (enExample) | 2023-07-21 |
Family
ID=74211221
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022502275A Pending JP2022541441A (ja) | 2019-07-17 | 2020-07-17 | 免疫エフェクター細胞操作およびその使用 |
| JP2025109951A Pending JP2025157281A (ja) | 2019-07-17 | 2025-06-30 | 免疫エフェクター細胞操作およびその使用 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025109951A Pending JP2025157281A (ja) | 2019-07-17 | 2025-06-30 | 免疫エフェクター細胞操作およびその使用 |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US20220275333A1 (enExample) |
| EP (1) | EP3999628A4 (enExample) |
| JP (2) | JP2022541441A (enExample) |
| KR (1) | KR20220035190A (enExample) |
| CN (1) | CN114258429A (enExample) |
| AU (1) | AU2020314969A1 (enExample) |
| BR (1) | BR112022000641A2 (enExample) |
| CA (1) | CA3146967A1 (enExample) |
| IL (1) | IL289830A (enExample) |
| MX (1) | MX2022000553A (enExample) |
| WO (1) | WO2021011919A1 (enExample) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11629340B2 (en) | 2017-03-03 | 2023-04-18 | Obsidian Therapeutics, Inc. | DHFR tunable protein regulation |
| CA3181118A1 (en) * | 2020-07-15 | 2022-01-20 | Yali ZHOU | Engineered immune cell for allotransplantation |
| US11459372B2 (en) | 2020-11-30 | 2022-10-04 | Crispr Therapeutics Ag | Gene-edited natural killer cells |
| EP4271798A1 (en) | 2020-12-30 | 2023-11-08 | CRISPR Therapeutics AG | Compositions and methods for differentiating stem cells into nk cells |
| MX2023008809A (es) | 2021-01-29 | 2023-08-04 | Allogene Therapeutics Inc | ATENUACIÓN O INACTIVACIÓN DE UNO O MÁS DE TAP2, NLRC5, ß2M, TRAC, RFX5, RFXAP Y RFXANK PARA MITIGAR EL RECONOCIMIENTO DE CÉLULAS T DE PRODUCTOS CELULARES ALOGÉNICOS. |
| CN117083375A (zh) * | 2021-01-29 | 2023-11-17 | 艾洛基治疗公司 | 敲低或敲除TAP2、NLRC5、β2m、TRAC、RFX5、RFXAP和RFXANK中的一个或多个以减轻同种异体细胞产物的T细胞识别 |
| CN116897202A (zh) * | 2021-02-24 | 2023-10-17 | 科济生物医药(上海)有限公司 | Tigit工程化细胞及其组合物 |
| WO2022179620A1 (zh) * | 2021-02-25 | 2022-09-01 | 克莱格医学有限公司 | Cd94工程化细胞及其组合物 |
| CA3209946A1 (en) * | 2021-03-05 | 2022-09-09 | Matthew Angel | Engineered immune cell therapies |
| CA3210702A1 (en) * | 2021-04-07 | 2022-10-13 | Century Therapeutics, Inc. | Gene transfer vectors and methods of engineering cells |
| WO2022251443A1 (en) * | 2021-05-26 | 2022-12-01 | FUJIFILM Cellular Dynamics, Inc. | Methods to prevent rapid silencing of genes in pluripotent stem cells |
| KR20240051112A (ko) | 2021-07-01 | 2024-04-19 | 인답타 세라뷰틱스 인코포레이티드 | 조작된 자연 살해(nk) 세포 및 관련 방법 |
| US20240307540A1 (en) * | 2021-07-02 | 2024-09-19 | Fate Therapeutics, Inc. | Protected effector cells and use thereof for allogeneic adoptive cell therapies |
| CA3228865A1 (en) * | 2021-08-18 | 2023-02-23 | Bahram Valamehr | Off-the-shelf ipsc-derived car-nk cell as monotherapy and in combination with antibody |
| IL312565A (en) * | 2021-11-08 | 2024-07-01 | Fate Therapeutics Inc | Engineered effector cells for trafficking of allogeneic cell therapies in solid tumors |
| US20250018034A1 (en) * | 2021-11-08 | 2025-01-16 | Fate Therapeutics, Inc. | Engineered effector cells and methods of enhancing ubiquitous targeting of solid tumors |
| KR20250005097A (ko) * | 2022-04-08 | 2025-01-09 | 페이트 세러퓨틱스, 인코포레이티드 | 고형 종양 표적화 골격을 갖는 세포 및 이의 용도 |
| KR20250004622A (ko) | 2022-04-08 | 2025-01-08 | 페이트 세러퓨틱스, 인코포레이티드 | 종양 표적화를 위한 키메라 항원 수용체 |
| US20260108554A1 (en) * | 2022-05-01 | 2026-04-23 | Factor Bioscience Inc. | Methods for reprogramming and gene editing cells |
| US20250375524A1 (en) | 2022-06-30 | 2025-12-11 | Indapta Therapeutics, Inc. | Combination of engineered natural killer (nk) cells and antibody therapy and related methods |
| WO2024047561A1 (en) * | 2022-09-02 | 2024-03-07 | Janssen Biotech, Inc. | Biomaterials and processes for immune synapse modulation of hypoimmunogenicity |
| EP4593868A1 (en) * | 2022-09-26 | 2025-08-06 | Institut Curie | Myeloid cells expressing il-2 and uses thereof for quick anticancer therapy |
| CN119923264A (zh) * | 2022-09-27 | 2025-05-02 | 基因泰克公司 | 抑制基因毒性应激以改善t细胞工程化 |
| GB202218144D0 (en) * | 2022-12-02 | 2023-01-18 | Univ Oxford Innovation Ltd | Product |
| CN120826463A (zh) * | 2023-03-31 | 2025-10-21 | 杭州启函生物科技有限公司 | 使用工程化细胞的癌症免疫疗法 |
| WO2025101471A1 (en) * | 2023-11-09 | 2025-05-15 | Merck Sharp & Dohme Llc | Anti-cd27 antibody cell-based biological potency assay |
| CN118703438B (zh) * | 2024-08-30 | 2025-01-14 | 星奕昂(上海)生物科技有限公司 | 一种活化和扩增自然杀伤细胞的方法及其用途 |
| CN119220607B (zh) * | 2024-12-03 | 2025-03-07 | 星奕昂(上海)生物科技有限公司 | 编辑tim3基因获得功能强化的car-nk细胞的方法与应用 |
| CN119552808A (zh) * | 2025-01-24 | 2025-03-04 | 上海元戊医学技术有限公司 | 通用型诱导多能干细胞及其制备方法与应用 |
Family Cites Families (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6352694B1 (en) | 1994-06-03 | 2002-03-05 | Genetics Institute, Inc. | Methods for inducing a population of T cells to proliferate using agents which recognize TCR/CD3 and ligands which stimulate an accessory molecule on the surface of the T cells |
| GB9710809D0 (en) | 1997-05-23 | 1997-07-23 | Medical Res Council | Nucleic acid binding proteins |
| GB9710807D0 (en) | 1997-05-23 | 1997-07-23 | Medical Res Council | Nucleic acid binding proteins |
| US6140081A (en) | 1998-10-16 | 2000-10-31 | The Scripps Research Institute | Zinc finger binding domains for GNN |
| US6534261B1 (en) | 1999-01-12 | 2003-03-18 | Sangamo Biosciences, Inc. | Regulation of endogenous gene expression in cells using zinc finger proteins |
| US6453242B1 (en) | 1999-01-12 | 2002-09-17 | Sangamo Biosciences, Inc. | Selection of sites for targeting by zinc finger proteins and methods of designing zinc finger proteins to bind to preselected sites |
| JP2002060786A (ja) | 2000-08-23 | 2002-02-26 | Kao Corp | 硬質表面用殺菌防汚剤 |
| US20040224385A1 (en) | 2001-08-20 | 2004-11-11 | Barbas Carlos F | Zinc finger binding domains for cnn |
| US7745140B2 (en) | 2002-01-03 | 2010-06-29 | The Trustees Of The University Of Pennsylvania | Activation and expansion of T-cells using an engineered multivalent signaling platform as a research tool |
| US7888121B2 (en) | 2003-08-08 | 2011-02-15 | Sangamo Biosciences, Inc. | Methods and compositions for targeted cleavage and recombination |
| US7972854B2 (en) | 2004-02-05 | 2011-07-05 | Sangamo Biosciences, Inc. | Methods and compositions for targeted cleavage and recombination |
| AU2005250408B2 (en) | 2004-05-27 | 2010-09-23 | The Trustees Of The University Of Pennsylvania | Novel artificial antigen presenting cells and uses therefor |
| JP5328018B2 (ja) * | 2006-06-05 | 2013-10-30 | 国立大学法人広島大学 | 抗cd38抗体を細胞表面に有する免疫担当細胞 |
| PT2816112T (pt) | 2009-12-10 | 2018-11-20 | Univ Iowa State Res Found Inc | Modificação do adn modificada pelo efector tal |
| WO2011159726A2 (en) | 2010-06-14 | 2011-12-22 | The Scripps Research Institute | Reprogramming of cells to a new fate |
| MX2014001222A (es) | 2011-07-29 | 2014-09-15 | Univ Pennsylvania | Receptores coestimuladores de cambio. |
| EP2814846B1 (en) | 2012-02-13 | 2020-01-08 | Seattle Children's Hospital d/b/a Seattle Children's Research Institute | Bispecific chimeric antigen receptors and therapeutic uses thereof |
| SG10201806573TA (en) | 2012-05-25 | 2018-09-27 | Cellectis | Methods for engineering allogeneic and immunosuppressive resistant t cell for immunotherapy |
| US9932607B2 (en) | 2013-11-15 | 2018-04-03 | The Board Of Trustees Of The Leland Stanford Junior University | Site-specific integration of transgenes into human cells |
| EP3104866A4 (en) | 2014-02-14 | 2017-08-02 | Bellicum Pharmaceuticals, Inc. | Methods for activating t cells using an inducible chimeric polypeptide |
| CN113699159A (zh) | 2014-03-28 | 2021-11-26 | 明尼苏达大学评议会 | 涉及经工程改造的cd16的多肽、细胞和方法 |
| AU2015312117A1 (en) | 2014-09-02 | 2017-03-02 | Bellicum Pharmaceuticals, Inc. | Costimulation of chimeric antigen receptors by Myd88 and CD40 polypeptides |
| WO2016154585A1 (en) * | 2015-03-26 | 2016-09-29 | Charles Sentman | Anti-mica antigen binding fragments, fusion molecules, cells which express and methods of using |
| US9790490B2 (en) * | 2015-06-18 | 2017-10-17 | The Broad Institute Inc. | CRISPR enzymes and systems |
| US12642852B1 (en) * | 2015-11-04 | 2026-06-02 | Fate Therapeutics, Inc. | Genomic engineering of pluripotent cells |
| CA3007473A1 (en) | 2015-12-14 | 2017-06-22 | Bellicum Pharmaceuticals, Inc. | Dual controls for therapeutic cell activation or elimination |
| EP3661552A4 (en) * | 2017-05-22 | 2021-08-25 | Dana-Farber Cancer Institute, Inc. | COMPOSITIONS AND METHODS FOR INHIBITING MICA / B REJECTION |
| AU2018359907A1 (en) * | 2017-11-06 | 2020-05-07 | Fred Hutchinson Cancer Center | Combination of a cell therapy and a gamma secretase inhibitor |
| US11639496B2 (en) * | 2017-12-05 | 2023-05-02 | Celyad S.A. | Reducing fratricide of immune cells expressing NKG2D-based receptors |
| CN111556892A (zh) * | 2017-12-08 | 2020-08-18 | 菲特治疗公司 | 使用增强的iPSC衍生的效应细胞的免疫疗法 |
| BR112020011017A2 (pt) * | 2017-12-22 | 2020-11-17 | Fate Therapeutics, Inc. | células efetoras imunes intensificadas e uso das mesmas |
-
2020
- 2020-07-17 KR KR1020227005062A patent/KR20220035190A/ko not_active Ceased
- 2020-07-17 JP JP2022502275A patent/JP2022541441A/ja active Pending
- 2020-07-17 US US17/627,574 patent/US20220275333A1/en active Pending
- 2020-07-17 BR BR112022000641A patent/BR112022000641A2/pt unknown
- 2020-07-17 EP EP20839948.5A patent/EP3999628A4/en active Pending
- 2020-07-17 CN CN202080058417.7A patent/CN114258429A/zh active Pending
- 2020-07-17 MX MX2022000553A patent/MX2022000553A/es unknown
- 2020-07-17 WO PCT/US2020/042657 patent/WO2021011919A1/en not_active Ceased
- 2020-07-17 CA CA3146967A patent/CA3146967A1/en active Pending
- 2020-07-17 AU AU2020314969A patent/AU2020314969A1/en active Pending
-
2021
- 2021-01-29 US US17/163,040 patent/US20210163622A1/en not_active Abandoned
-
2022
- 2022-01-13 IL IL289830A patent/IL289830A/en unknown
-
2025
- 2025-06-30 JP JP2025109951A patent/JP2025157281A/ja active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2022550899A5 (enExample) | ||
| JP2022548943A5 (enExample) | ||
| JP2021505131A5 (enExample) | ||
| JP2022510207A5 (enExample) | ||
| JP2023505206A5 (enExample) | ||
| JP2023530704A5 (enExample) | ||
| US12404338B2 (en) | Anti CD30 chimeric antigen receptor and its use | |
| JP2023549098A5 (enExample) | ||
| JP2023548467A5 (enExample) | ||
| JP2021519061A5 (enExample) | ||
| JP7623020B2 (ja) | 同種異系移植のための操作された免疫細胞 | |
| JP2023548829A5 (enExample) | ||
| KR102600544B1 (ko) | 트랜스진 유전자 태그 및 사용 방법 | |
| JP2023153141A (ja) | 治療免疫細胞の有効性を改良するための方法 | |
| Maher | Immunotherapy of malignant disease using chimeric antigen receptor engrafted T cells | |
| JP2023545992A5 (enExample) | ||
| KR20230129983A (ko) | 조작된 세포 요법을 위한 표적화된 사이토카인 구축물 | |
| RS62870B1 (sr) | Himerni antigenski receptori sa ciljanim delovanjem na receptore spregnute sa g-proteinom i njihove upotrebe | |
| US10941202B2 (en) | Isolated human mesenchymal stem cell expressing a bispecific antibody that binds CD33 and CD3 and method of using to treat cancer | |
| JP2024502157A (ja) | 樹状細胞活性化キメラ抗原受容体及びその使用 | |
| JP2024533375A5 (enExample) | ||
| JP2024515920A5 (enExample) | ||
| KR20210018838A (ko) | 유전자 조작된 세포 및 응용 | |
| AU2021338819A1 (en) | Chimeric antigen receptor comprising novel co-stimulatory domain and use thereof | |
| JP2024525492A5 (enExample) |