JP2023527962A5 - - Google Patents

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Publication number
JP2023527962A5
JP2023527962A5 JP2022567119A JP2022567119A JP2023527962A5 JP 2023527962 A5 JP2023527962 A5 JP 2023527962A5 JP 2022567119 A JP2022567119 A JP 2022567119A JP 2022567119 A JP2022567119 A JP 2022567119A JP 2023527962 A5 JP2023527962 A5 JP 2023527962A5
Authority
JP
Japan
Prior art keywords
adc
pharmaceutically acceptable
acceptable salt
cancer
trop2
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2022567119A
Other languages
English (en)
Japanese (ja)
Other versions
JP2023527962A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2021/030198 external-priority patent/WO2021225892A1/en
Publication of JP2023527962A publication Critical patent/JP2023527962A/ja
Publication of JP2023527962A5 publication Critical patent/JP2023527962A5/ja
Pending legal-status Critical Current

Links

JP2022567119A 2020-05-03 2021-04-30 抗trop2抗体を含む抗体薬物複合体(adc)、かかるadcを含む組成物、ならびにそれらを作製および使用する方法 Pending JP2023527962A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
CNPCT/CN2020/088565 2020-05-03
CN2020088565 2020-05-03
CNPCT/CN2021/086849 2021-04-13
CN2021086849 2021-04-13
PCT/US2021/030198 WO2021225892A1 (en) 2020-05-03 2021-04-30 Antibody-drug conjugates (adcs) comprising an anti-trop-2 antibody, compositions comprising such adcs, as well as methods of making and using the same

Publications (2)

Publication Number Publication Date
JP2023527962A JP2023527962A (ja) 2023-07-03
JP2023527962A5 true JP2023527962A5 (https=) 2024-05-10

Family

ID=76012056

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022567119A Pending JP2023527962A (ja) 2020-05-03 2021-04-30 抗trop2抗体を含む抗体薬物複合体(adc)、かかるadcを含む組成物、ならびにそれらを作製および使用する方法

Country Status (11)

Country Link
US (1) US20240082415A1 (https=)
EP (1) EP4146283A1 (https=)
JP (1) JP2023527962A (https=)
KR (1) KR20230087414A (https=)
CN (1) CN116963782A (https=)
AU (1) AU2021267995A1 (https=)
CA (1) CA3177562A1 (https=)
IL (1) IL297830A (https=)
MX (1) MX2022013768A (https=)
TW (1) TW202200212A (https=)
WO (1) WO2021225892A1 (https=)

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CN116199784A (zh) * 2021-11-30 2023-06-02 泽达生物医药有限公司 抗trop-2/pd-l1双特异性抗体
CA3256048A1 (en) 2022-04-13 2023-10-19 Arcus Biosciences, Inc. POLYTHERAPY FOR THE TREATMENT OF CANCERS EXPRESSING A TUMOR ANTIGEN
JP2025512384A (ja) 2022-04-13 2025-04-17 ギリアード サイエンシーズ, インコーポレイテッド Trop-2発現がんを治療するための併用療法
US20250381283A1 (en) * 2022-06-27 2025-12-18 Bio-Thera Solutions, Ltd. Method for treating solid tumor
WO2024207177A1 (en) * 2023-04-04 2024-10-10 Genequantum Healthcare (Suzhou) Co., Ltd. Antibody, linkers, payload, conjugates and applications thereof
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WO2024155761A1 (en) * 2023-01-20 2024-07-25 Adcentrx Therapeutics Inc. Drug conjugates and methods of preparing and using the same
WO2024199466A1 (zh) 2023-03-31 2024-10-03 应世生物科技(南京)有限公司 提高大分子药物在肿瘤组织中的浓度的方法
AU2024288808A1 (en) 2023-07-07 2026-01-22 Shanghai Escugen Biotechnology Co., Ltd. Linker-drug molecule and antibody drug conjugate, preparation method therefor and use thereof
WO2025110502A1 (ko) 2023-11-20 2025-05-30 이화여자대학교 산학협력단 이량체 tctp의 수용체인 cd300c 및 이의 용도

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