JP2011505371A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2011505371A5 JP2011505371A5 JP2010536173A JP2010536173A JP2011505371A5 JP 2011505371 A5 JP2011505371 A5 JP 2011505371A5 JP 2010536173 A JP2010536173 A JP 2010536173A JP 2010536173 A JP2010536173 A JP 2010536173A JP 2011505371 A5 JP2011505371 A5 JP 2011505371A5
- Authority
- JP
- Japan
- Prior art keywords
- cancer
- seq
- chain variable
- variable region
- complex
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US99169007P | 2007-11-30 | 2007-11-30 | |
| PCT/US2008/084899 WO2009073524A2 (en) | 2007-11-30 | 2008-11-26 | Conjugates of anti-rg-1 antibodies |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2011505371A JP2011505371A (ja) | 2011-02-24 |
| JP2011505371A5 true JP2011505371A5 (https=) | 2011-11-04 |
Family
ID=40427118
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010536173A Withdrawn JP2011505371A (ja) | 2007-11-30 | 2008-11-26 | 抗−ｒｇ−１抗体の複合体 |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US20110020329A1 (https=) |
| EP (1) | EP2211908A2 (https=) |
| JP (1) | JP2011505371A (https=) |
| KR (1) | KR20100101122A (https=) |
| CN (1) | CN101951960A (https=) |
| AR (1) | AR069746A1 (https=) |
| AU (1) | AU2008331507A1 (https=) |
| BR (1) | BRPI0819765A2 (https=) |
| CA (1) | CA2707443A1 (https=) |
| CL (1) | CL2008003525A1 (https=) |
| CO (1) | CO6210734A2 (https=) |
| EA (1) | EA201000921A1 (https=) |
| IL (1) | IL206060A0 (https=) |
| MX (1) | MX2010005683A (https=) |
| NZ (1) | NZ586514A (https=) |
| TW (1) | TW200930407A (https=) |
| WO (1) | WO2009073524A2 (https=) |
| ZA (1) | ZA201003729B (https=) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2005263555B2 (en) * | 2004-07-16 | 2011-01-27 | Amgen Research (Munich) Gmbh | Expression-enhanced polypeptides |
| ES2647317T3 (es) | 2008-11-03 | 2017-12-20 | Syntarga B.V. | Análogos de CC-1065 y sus conjugados |
| PT3056203T (pt) | 2010-04-21 | 2018-02-15 | Syntarga Bv | Conjugados de análogos de cc-1065 e ligantes bifuncionais |
| EP2576621B1 (en) | 2010-05-27 | 2019-04-10 | Genmab A/S | Monoclonal antibodies against her2 |
| CA2800769C (en) | 2010-05-27 | 2021-11-02 | Genmab A/S | Monoclonal antibodies against her2 epitope |
| US8852599B2 (en) * | 2011-05-26 | 2014-10-07 | Bristol-Myers Squibb Company | Immunoconjugates, compositions for making them, and methods of making and use |
| RU2680404C2 (ru) | 2014-01-10 | 2019-02-21 | Синтон Байофармасьютикалс Б. В. | Способ очистки cys-связанных конъюгатов антитело-лекарственное средство |
| US10562977B2 (en) * | 2014-01-29 | 2020-02-18 | Shanghai Hengrui Pharmaceutical Co., Ltd. | Ligand-cytotoxic drug conjugate, preparation method thereof, and uses thereof |
| MY202018A (en) | 2017-07-31 | 2024-03-29 | Trishula Therapeutics Inc | Anti-cd39 antibodies, compositions comprising anti-cd39 antibodies and methods of using anti-cd39 antibodies |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4912227A (en) * | 1984-02-21 | 1990-03-27 | The Upjohn Company | 1,2,8,8A-tetrahydrocyclopropa(c)pyrrolo(3,2-e)-indol-4-(5H)-ones and related compounds |
| US4978757A (en) * | 1984-02-21 | 1990-12-18 | The Upjohn Company | 1,2,8,8a-tetrahydrocyclopropa (C) pyrrolo [3,2-e)]-indol-4(5H)-ones and related compounds |
| US5332837A (en) * | 1986-12-19 | 1994-07-26 | The Upjohn Company | CC-1065 analogs |
| US5084468A (en) * | 1988-08-11 | 1992-01-28 | Kyowa Hakko Kogyo Co., Ltd. | Dc-88a derivatives |
| JP2598116B2 (ja) * | 1988-12-28 | 1997-04-09 | 協和醗酵工業株式会社 | 新規物質ｄｃ１１３ |
| US5187186A (en) * | 1989-07-03 | 1993-02-16 | Kyowa Hakko Kogyo Co., Ltd. | Pyrroloindole derivatives |
| JP2510335B2 (ja) * | 1989-07-03 | 1996-06-26 | 協和醗酵工業株式会社 | Ｄｃ―８８ａ誘導体 |
| CA2078118C (en) * | 1990-04-25 | 1999-11-16 | Paul A. Aristoff | Cc-1065 analogs |
| US6214345B1 (en) * | 1993-05-14 | 2001-04-10 | Bristol-Myers Squibb Co. | Lysosomal enzyme-cleavable antitumor drug conjugates |
| US5641780A (en) * | 1994-04-22 | 1997-06-24 | Kyowa Hakko Kogyo Co., Ltd. | Pyrrolo-indole derivatives |
| JPH07309761A (ja) * | 1994-05-20 | 1995-11-28 | Kyowa Hakko Kogyo Co Ltd | デュオカルマイシン誘導体の安定化法 |
| US5871969A (en) * | 1996-02-12 | 1999-02-16 | Human Genome Sciences, Inc. | Nucleic acids encoding human neuronal attachment factor-1 |
| US6682902B2 (en) * | 1999-12-16 | 2004-01-27 | Schering Aktiengesellschaft | DNA encoding a novel RG1 polypeptide |
| US6989452B2 (en) * | 2001-05-31 | 2006-01-24 | Medarex, Inc. | Disulfide prodrugs and linkers and stabilizers useful therefor |
| EP1423110A4 (en) * | 2001-09-07 | 2005-04-27 | Scripps Research Inst | CBI ANALOGUE OF CC-1065 AND DUOCARMYCINES |
| US7091186B2 (en) * | 2001-09-24 | 2006-08-15 | Seattle Genetics, Inc. | p-Amidobenzylethers in drug delivery agents |
| MXPA06000798A (es) * | 2003-07-22 | 2006-04-07 | Schering Ag | Anticuerpos de rg1 y usos de los mismos. |
| JP4806680B2 (ja) * | 2004-05-19 | 2011-11-02 | メダレックス インコーポレイテッド | 自己犠牲リンカー及び薬剤複合体 |
| US7691962B2 (en) * | 2004-05-19 | 2010-04-06 | Medarex, Inc. | Chemical linkers and conjugates thereof |
| US7714016B2 (en) * | 2005-04-08 | 2010-05-11 | Medarex, Inc. | Cytotoxic compounds and conjugates with cleavable substrates |
| EP2354163A3 (en) * | 2005-09-26 | 2013-04-24 | Medarex, Inc. | Conjugates of duocarmycin and anti-CD70 or anti-PSMA antibodies |
| WO2007059404A2 (en) * | 2005-11-10 | 2007-05-24 | Medarex, Inc. | Duocarmycin derivatives as novel cytotoxic compounds and conjugates |
| ES2469676T3 (es) * | 2006-05-25 | 2014-06-18 | Bayer Intellectual Property Gmbh | Complejos moleculares dim�ricos |
-
2008
- 2008-11-26 US US12/745,337 patent/US20110020329A1/en not_active Abandoned
- 2008-11-26 WO PCT/US2008/084899 patent/WO2009073524A2/en not_active Ceased
- 2008-11-26 CL CL2008003525A patent/CL2008003525A1/es unknown
- 2008-11-26 CA CA2707443A patent/CA2707443A1/en not_active Abandoned
- 2008-11-26 TW TW097145816A patent/TW200930407A/zh unknown
- 2008-11-26 AU AU2008331507A patent/AU2008331507A1/en not_active Abandoned
- 2008-11-26 EA EA201000921A patent/EA201000921A1/ru unknown
- 2008-11-26 AR ARP080105135A patent/AR069746A1/es not_active Application Discontinuation
- 2008-11-26 NZ NZ586514A patent/NZ586514A/en not_active IP Right Cessation
- 2008-11-26 MX MX2010005683A patent/MX2010005683A/es not_active Application Discontinuation
- 2008-11-26 CN CN2008801259196A patent/CN101951960A/zh active Pending
- 2008-11-26 EP EP08858236A patent/EP2211908A2/en not_active Withdrawn
- 2008-11-26 JP JP2010536173A patent/JP2011505371A/ja not_active Withdrawn
- 2008-11-26 KR KR1020107014394A patent/KR20100101122A/ko not_active Withdrawn
- 2008-11-26 BR BRPI0819765 patent/BRPI0819765A2/pt not_active IP Right Cessation
-
2010
- 2010-05-25 ZA ZA2010/03729A patent/ZA201003729B/en unknown
- 2010-05-28 CO CO10064681A patent/CO6210734A2/es not_active Application Discontinuation
- 2010-05-30 IL IL206060A patent/IL206060A0/en unknown
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2011505371A5 (https=) | ||
| ES2982012T3 (es) | Materiales biológicos y usos de los mismos | |
| RU2476441C2 (ru) | Cd19-связывающие средства и их применение | |
| JP2020502271A5 (https=) | ||
| JP2009505676A5 (https=) | ||
| JP2009506790A5 (https=) | ||
| JP2010535713A5 (https=) | ||
| JP2018070648A5 (https=) | ||
| JP2010531140A5 (https=) | ||
| WO2021248048A9 (en) | Antibody-drug conjugates containing an anti-mesothelin antibody and uses thereof | |
| RU2013142004A (ru) | Конъюгаты "антитело-лекарственное средство" | |
| JP2015534579A5 (https=) | ||
| JP2015527318A5 (https=) | ||
| JP2014502955A5 (https=) | ||
| JP2013518912A5 (https=) | ||
| JP2012522513A5 (https=) | ||
| CA2595610A1 (en) | Antibodies directed to angiopoietin-2 and uses thereof | |
| JP2015528818A5 (https=) | ||
| JP2015534577A5 (https=) | ||
| JP2004534020A5 (https=) | ||
| JP2016503295A5 (https=) | ||
| JP2015534578A5 (https=) | ||
| JP2017534253A5 (https=) | ||
| JP2010511388A5 (https=) | ||
| JP2014522850A5 (https=) |