JP2023552791A5 - - Google Patents
Info
- Publication number
- JP2023552791A5 JP2023552791A5 JP2023534648A JP2023534648A JP2023552791A5 JP 2023552791 A5 JP2023552791 A5 JP 2023552791A5 JP 2023534648 A JP2023534648 A JP 2023534648A JP 2023534648 A JP2023534648 A JP 2023534648A JP 2023552791 A5 JP2023552791 A5 JP 2023552791A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyldiyl
- peg
- alkyl
- immunocomplex
- cancer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063124421P | 2020-12-11 | 2020-12-11 | |
| US63/124,421 | 2020-12-11 | ||
| PCT/US2021/062833 WO2022125915A1 (en) | 2020-12-11 | 2021-12-10 | Anti-her2 immunoconjugates, and uses thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2023552791A JP2023552791A (ja) | 2023-12-19 |
| JP2023552791A5 true JP2023552791A5 (https=) | 2024-12-05 |
Family
ID=79425413
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023534648A Withdrawn JP2023552791A (ja) | 2020-12-11 | 2021-12-10 | 抗ｈｅｒ２免疫複合体、及びその使用 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20240042050A1 (https=) |
| EP (1) | EP4259211A1 (https=) |
| JP (1) | JP2023552791A (https=) |
| CN (1) | CN116897054A (https=) |
| CA (1) | CA3200320A1 (https=) |
| WO (1) | WO2022125915A1 (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2023154318A1 (en) * | 2022-02-09 | 2023-08-17 | Bolt Biotherapeutics, Inc. | Anti-tr0p2, aminobenzazepine immunoconjugates, and uses thereof |
| WO2024173384A1 (en) | 2023-02-14 | 2024-08-22 | Bolt Biotherapeutics, Inc. | Aza-benzazepine immunoconjugates, and uses thereof |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3101690B2 (ja) | 1987-03-18 | 2000-10-23 | エス・ビィ・２・インコーポレイテッド | 変性抗体の、または変性抗体に関する改良 |
| JP3040121B2 (ja) | 1988-01-12 | 2000-05-08 | ジェネンテク，インコーポレイテッド | 増殖因子レセプターの機能を阻害することにより腫瘍細胞を処置する方法 |
| EP1400536A1 (en) | 1991-06-14 | 2004-03-24 | Genentech Inc. | Method for making humanized antibodies |
| WO1994004679A1 (en) | 1991-06-14 | 1994-03-03 | Genentech, Inc. | Method for making humanized antibodies |
| US6800738B1 (en) | 1991-06-14 | 2004-10-05 | Genentech, Inc. | Method for making humanized antibodies |
| NZ507557A (en) | 1998-05-06 | 2003-10-31 | Genentech Inc | Protein purification by ion exchange chromatography |
| US6949245B1 (en) | 1999-06-25 | 2005-09-27 | Genentech, Inc. | Humanized anti-ErbB2 antibodies and treatment with anti-ErbB2 antibodies |
| JP2003531149A (ja) | 2000-04-13 | 2003-10-21 | ザ・ロツクフエラー・ユニバーシテイ | 抗体由来の免疫応答の増強 |
| DK1791565T3 (en) | 2004-09-23 | 2016-08-01 | Genentech Inc | Cysteingensplejsede antibodies and conjugates |
| WO2006073921A2 (en) | 2004-12-30 | 2006-07-13 | The Rockefeller University | Compositions and methods for enhanced dendritic cell maturation and function |
| US20080286819A1 (en) | 2005-11-07 | 2008-11-20 | Ravetch Jeffrey V | Reagents, Methods and Systems for Selecting a Cytotoxic Antibody or Variant Thereof |
| CL2008001334A1 (es) | 2007-05-08 | 2008-09-22 | Genentech Inc | Anticuerpo anti-muc16 disenado con cisteina; conjugado que lo comprende; metodo de produccion; formulacion farmaceutica que lo comprende; y su uso para tratar el cancer. |
| NZ584514A (en) | 2007-10-19 | 2012-07-27 | Genentech Inc | Cysteine engineered anti-tenb2 antibodies and antibody drug conjugates |
| US20120121615A1 (en) | 2010-11-17 | 2012-05-17 | Flygare John A | Alaninyl maytansinol antibody conjugates |
| AU2015349878A1 (en) | 2014-11-21 | 2017-05-25 | Bristol-Myers Squibb Company | Antibodies against CD73 and uses thereof |
| AU2019337654A1 (en) * | 2018-09-12 | 2021-04-08 | Silverback Therapeutics, Inc. | Substituted benzazepine compounds, conjugates, and uses thereof |
| JP7558205B2 (ja) * | 2019-06-13 | 2024-09-30 | ボルト バイオセラピューティクス、インコーポレーテッド | 高分子支持アミノベンズアピン化合物 |
| US20200390899A1 (en) * | 2019-06-13 | 2020-12-17 | Bolt Biotherapeutics, Inc. | Aminobenzazepine compounds, immunoconjugates, and uses thereof |
| US20230293716A1 (en) * | 2020-05-08 | 2023-09-21 | Bolt Biotherapeutics, Inc. | Elastase-substrate, peptide linker immunoconjugates, and uses thereof |
-
2021
- 2021-12-10 CN CN202180092533.5A patent/CN116897054A/zh active Pending
- 2021-12-10 EP EP21841073.6A patent/EP4259211A1/en not_active Withdrawn
- 2021-12-10 US US18/038,897 patent/US20240042050A1/en active Pending
- 2021-12-10 WO PCT/US2021/062833 patent/WO2022125915A1/en not_active Ceased
- 2021-12-10 JP JP2023534648A patent/JP2023552791A/ja not_active Withdrawn
- 2021-12-10 CA CA3200320A patent/CA3200320A1/en active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2023553421A5 (ja) | 抗ｃｅａ免疫複合体、及びその使用 | |
| JP2024523453A5 (https=) | ||
| JP2022553702A5 (https=) | ||
| JP2023552792A5 (https=) | ||
| JP2022537158A5 (https=) | ||
| JP2022549510A5 (https=) | ||
| JP2023524271A5 (https=) | ||
| JP2023105175A (ja) | グルクロニド薬物－リンカーの調製のためのプロセスおよびその中間体 | |
| CA3186295A1 (en) | Camptothecin drug having high-stability hydrophilic connecting unit and conjugate thereof | |
| JP2024059609A5 (https=) | ||
| IL312845B1 (en) | Extacan derivatives, charge-linkers, and their conjugates | |
| JP2022546110A5 (https=) | ||
| JP2024533356A5 (https=) | ||
| CA3044898A1 (en) | Di-substituted maleic amide linker for antibody-drug conjugating and preparation method and use thereof | |
| RU2748992C2 (ru) | Системы доставки для контролируемого высвобождения лекарственного средства | |
| JP2023552791A5 (https=) | ||
| JP2023527962A5 (https=) | ||
| JP2024511088A5 (https=) | ||
| JP2022554094A5 (https=) | ||
| JP2019502650A5 (ja) | 抗ＥｒｂＢ２抗体−薬物コンジュゲート及びその組成物、そのための調製方法、並びにその使用 | |
| HRP20230275T1 (hr) | Antitijelo-lijek konjugati koji sadrže derivate ekteinascidina | |
| JP2023552790A5 (https=) | ||
| JP2024501453A5 (https=) | ||
| CA2338000C (en) | Water-soluble 4-thio-maleimido derivatives and methods for their production | |
| WO2024227439A1 (zh) | 具有靶向作用的偶联物及其制备方法和用途 |