JP2023523600A5 - - Google Patents

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Publication number
JP2023523600A5
JP2023523600A5 JP2022564470A JP2022564470A JP2023523600A5 JP 2023523600 A5 JP2023523600 A5 JP 2023523600A5 JP 2022564470 A JP2022564470 A JP 2022564470A JP 2022564470 A JP2022564470 A JP 2022564470A JP 2023523600 A5 JP2023523600 A5 JP 2023523600A5
Authority
JP
Japan
Prior art keywords
humanized antibody
antibody according
variable domain
antibody
single variable
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2022564470A
Other languages
English (en)
Japanese (ja)
Other versions
JP2023523600A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/CN2021/088674 external-priority patent/WO2021213435A1/zh
Publication of JP2023523600A publication Critical patent/JP2023523600A/ja
Publication of JP2023523600A5 publication Critical patent/JP2023523600A5/ja
Pending legal-status Critical Current

Links

JP2022564470A 2020-04-22 2021-04-21 ヒトプログラム細胞死リガンド1(pd-l1)を標的とする単一可変ドメイン抗体およびその誘導体 Pending JP2023523600A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CN202010324761 2020-04-22
CN202010324761.8 2020-04-22
PCT/CN2021/088674 WO2021213435A1 (zh) 2020-04-22 2021-04-21 一种靶向人程序性死亡配体1(pd-l1)的单可变域抗体及其衍生物

Publications (2)

Publication Number Publication Date
JP2023523600A JP2023523600A (ja) 2023-06-06
JP2023523600A5 true JP2023523600A5 (enExample) 2024-05-01

Family

ID=78095333

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022564470A Pending JP2023523600A (ja) 2020-04-22 2021-04-21 ヒトプログラム細胞死リガンド1(pd-l1)を標的とする単一可変ドメイン抗体およびその誘導体

Country Status (5)

Country Link
US (1) US20230279115A1 (enExample)
EP (1) EP4144758A4 (enExample)
JP (1) JP2023523600A (enExample)
CN (1) CN113527488B (enExample)
WO (1) WO2021213435A1 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115505045A (zh) * 2021-06-23 2022-12-23 迈威(上海)生物科技股份有限公司 靶向lag-3和pd-l1的新型双特异抗体及其应用
CN113940997B (zh) * 2021-12-21 2022-04-08 迈威(上海)生物科技股份有限公司 一种双特异性抗体的稳定制剂
CN115925947B (zh) * 2022-09-27 2023-08-22 上海百英生物科技股份有限公司 一种亲和力成熟方法及抗人pd-l1单域抗体的亲和力成熟
CN120380023A (zh) * 2022-10-20 2025-07-25 基础应用医学研究基金会 用于癌症治疗的纳米抗体
CN117660358B (zh) * 2024-01-31 2024-05-14 青岛华赛伯曼医学细胞生物有限公司 表达分泌型融合蛋白的工程化免疫细胞及其应用
WO2025242206A1 (zh) * 2024-05-24 2025-11-27 苏州康宁杰瑞生物科技有限公司 基于pd-l1结合多肽的多功能分子

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CN106397592A (zh) * 2015-07-31 2017-02-15 苏州康宁杰瑞生物科技有限公司 针对程序性死亡配体(pd-l1)的单域抗体及其衍生蛋白
CN107216389B (zh) * 2016-03-18 2022-03-29 和迈生物科技有限公司 抗pd-l1纳米抗体及其编码序列和用途
CN107400166A (zh) * 2016-05-19 2017-11-28 苏州康宁杰瑞生物科技有限公司 针对ctla4的单域抗体及其衍生蛋白
CN109485726B (zh) * 2017-09-13 2022-07-08 和迈生物科技有限公司 放射性标记抗纳米抗体在癌症的预后、诊断中的应用
EP3710480A4 (en) * 2017-11-17 2021-12-15 Nanjing Legend Biotech Co., Ltd. SINGLE-DOMAIN ANTIBODIES AND VARIANTS OF THEM DIRECTED AGAINST PD-L1
CN110144010B9 (zh) * 2018-02-14 2021-01-05 上海洛启生物医药技术有限公司 阻断型pd-l1驼源单域抗体及其用途
CN109265548B (zh) * 2018-09-13 2021-05-18 东南大学 抗pd-l1纳米抗体及其编码序列、制备方法和应用
CN110627904B (zh) * 2019-10-31 2020-07-10 南京蓝盾生物科技有限公司 抗人gpc3单克隆抗体
CN113968903A (zh) * 2020-07-24 2022-01-25 迈威(上海)生物科技股份有限公司 TGF-β RII突变体及其融合蛋白

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