JP2023518976A5 - - Google Patents

Info

Publication number
JP2023518976A5
JP2023518976A5 JP2022558088A JP2022558088A JP2023518976A5 JP 2023518976 A5 JP2023518976 A5 JP 2023518976A5 JP 2022558088 A JP2022558088 A JP 2022558088A JP 2022558088 A JP2022558088 A JP 2022558088A JP 2023518976 A5 JP2023518976 A5 JP 2023518976A5
Authority
JP
Japan
Prior art keywords
composition according
nanoemulsion
nanoemulsion composition
virus
oil
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2022558088A
Other languages
English (en)
Japanese (ja)
Other versions
JP2023518976A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2021/019103 external-priority patent/WO2021194672A1/en
Publication of JP2023518976A publication Critical patent/JP2023518976A/ja
Publication of JP2023518976A5 publication Critical patent/JP2023518976A5/ja
Pending legal-status Critical Current

Links

JP2022558088A 2020-03-23 2021-02-22 Rnaを送達するための組成物および方法 Pending JP2023518976A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202062993307P 2020-03-23 2020-03-23
US62/993,307 2020-03-23
US202063054754P 2020-07-21 2020-07-21
US63/054,754 2020-07-21
PCT/US2021/019103 WO2021194672A1 (en) 2020-03-23 2021-02-22 Compositions and methods for delivery of rna

Publications (2)

Publication Number Publication Date
JP2023518976A JP2023518976A (ja) 2023-05-09
JP2023518976A5 true JP2023518976A5 (https=) 2024-02-08

Family

ID=74885039

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022558088A Pending JP2023518976A (ja) 2020-03-23 2021-02-22 Rnaを送達するための組成物および方法

Country Status (10)

Country Link
US (15) US20220110881A1 (https=)
EP (1) EP4126021A1 (https=)
JP (1) JP2023518976A (https=)
KR (1) KR20220156933A (https=)
CN (1) CN115551548A (https=)
AU (1) AU2021241355A1 (https=)
BR (1) BR112022019124A2 (https=)
CA (1) CA3172489A1 (https=)
GB (2) GB2605538B (https=)
WO (1) WO2021194672A1 (https=)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11679163B2 (en) 2019-09-20 2023-06-20 Hdt Bio Corp. Compositions and methods for delivery of RNA
KR20220156933A (ko) 2020-03-23 2022-11-28 에이치디티 바이오 코포레이션 Rna의 전달을 위한 조성물 및 방법
US20220193225A1 (en) * 2020-08-31 2022-06-23 Bruce Lyday Compositions and methods for sars-2 vaccine with virus replicative particles and recombinant glycoproteins
JP2024535354A (ja) 2021-09-22 2024-09-30 エイチディーティー バイオ コーポレーション がん治療組成物およびその使用
CA3232719A1 (en) 2021-09-22 2023-03-30 Steven Gregory REED Sars-cov-2 rna vaccine compositions and methods of use
WO2023048760A1 (en) * 2021-09-22 2023-03-30 Hdt Bio Corp. Rna vaccines against infectious diseases
EP4404919A4 (en) 2021-09-22 2025-08-20 Hdt Bio Corp DRIED NANOPARTICLE COMPOSITIONS
EP4404977A4 (en) * 2021-09-22 2025-07-30 Hdt Bio Corp NUCLEIC ACID SENSOR AGONIST COMPOSITIONS AND USES THEREOF
EP4460326A4 (en) * 2022-01-07 2026-03-11 Hdt Bio Corp COMPOSITIONS AND METHODS ASSOCIATED WITH MULTIVALENT IMMUNE RESPONSES
US11648332B1 (en) * 2022-04-22 2023-05-16 Innovative Technologies Universal air purification system
CN116942610A (zh) * 2022-04-29 2023-10-27 北京祥瑞生物制品股份有限公司 一种核酸药物递送系统及其制备方法
WO2023228116A1 (en) * 2022-05-24 2023-11-30 Access To Advanced Health Institute Intranasal administration of thermostable rna vaccines
WO2024020453A2 (en) * 2022-07-20 2024-01-25 Hdt Bio Corp. Immune system modulators and uses thereof
WO2024031051A1 (en) 2022-08-05 2024-02-08 Life Technologies Corporation Lipids for nucleic acid delivery
WO2024148169A1 (en) * 2023-01-06 2024-07-11 Hdt Bio Corp. Nanoparticle complexes for enhanced safety
EP4687991A1 (en) 2023-03-30 2026-02-11 Ose Immunotherapeutics Lipid-based nanoparticle targeted at activated immune cells for the expression of immune cell enhancing molecule and use thereof
WO2024200820A1 (en) 2023-03-30 2024-10-03 Ose Immunotherapeutics Method of synthesis of targeted lipid nanoparticle and uses thereof
WO2024216171A2 (en) * 2023-04-13 2024-10-17 Massachusetts Institute Of Technology Lipid nanoparticles for delivery of agents
WO2025027116A1 (en) 2023-08-01 2025-02-06 Institut Curie Nanoparticles comprising nucleic acid sequences encoding cyclic gmp-amp synthase
WO2025231068A1 (en) * 2024-04-30 2025-11-06 The Regents Of The University Of Michigan Compositions and methods for enhancing systemic and mucosal immune responses

Family Cites Families (85)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1156781B1 (en) 1999-02-26 2005-06-08 Chiron Corporation Microemulsions with adsorbed macromolecules and microparticles
AU7398200A (en) 1999-09-17 2001-04-24 Aventis Pasteur Limited Chlamydia antigens and corresponding dna fragments and uses thereof
CA2434546C (en) 2001-01-12 2012-09-11 Chiron Corporation Induction of immune response by a replication-defective venezuelan equine encephalitis-sindbis chimeric virus replicon particle encoding an antigen
ES2330202T5 (es) 2001-09-06 2014-01-20 Alphavax, Inc. Sistemas vectores basados en replicones de alfavirus
US7416840B2 (en) 2002-12-13 2008-08-26 Fox Chase Cancer Center Replication of hepatitis C virus in non-hepatic epithelial and mouse hepatic cells
US20090252721A1 (en) 2003-09-18 2009-10-08 Thomas Buschmann Differentially expressed tumour-specific polypeptides for use in the diagnosis and treatment of cancer
WO2005107760A1 (en) 2004-04-30 2005-11-17 Irm Llc Compounds and compositions as inducers of keratinocyte differentiation
CN1989250B (zh) 2004-05-18 2013-11-20 阿尔法瓦克斯公司 Tc-83衍生的甲病毒属载体、颗粒和方法
TWI388344B (zh) 2005-08-23 2013-03-11 Celsion Corp 儲存奈米微粒調合物之方法
KR101499750B1 (ko) 2006-02-27 2015-03-06 더 보드 오브 리전츠 오브 더 유니버시티 오브 텍사스 시스템 가감염성 플라비바이러스 및 이들의 용도
PL2068918T5 (pl) 2006-09-26 2024-12-02 Access To Advanced Health Institute Kompozycja szczepionki zawierająca syntetyczny adiuwant
BRPI0809926B8 (pt) 2007-04-04 2021-05-25 Infectious Disease Res Inst composição que compreende antígenos de mycobacterium tuberculosis, polipeptídeo de fusão isolado, polinucleotídeo isolado que codifica o dito polipeptídeo e uso da dita composição para estimular uma resposta imune protetora
CN101868180A (zh) * 2007-10-09 2010-10-20 圣路易斯华盛顿州立大学 成像粒子
US9370558B2 (en) 2008-02-13 2016-06-21 President And Fellows Of Harvard College Controlled delivery of TLR agonists in structural polymeric devices
KR20110126717A (ko) 2009-02-24 2011-11-23 더 스크립스 리서치 인스티튜트 단백질 생성 증강을 위한 mrna 1차 구조의 재구조화
CA2764374C (en) 2009-06-05 2019-11-19 Infectious Disease Research Institute Synthetic glucopyranosyl lipid adjuvants
DK2509634T3 (en) 2009-12-11 2019-04-23 Pfizer Stable formulations for lyophilization of therapeutic particles
KR101915699B1 (ko) 2010-06-10 2018-11-06 유니버시티 오브 워싱톤 스루 이츠 센터 포 커머셜리제이션 데스모글레인 2(디에스쥐2)와 아데노바이러스의 상호작용을 위한 방법 및 시스템
US9555136B2 (en) 2010-06-21 2017-01-31 University Of Washington Through Its Center For Commercialization Coated magnetic nanoparticles
NZ606591A (en) 2010-07-06 2015-02-27 Novartis Ag Cationic oil-in-water emulsions
ES2646669T3 (es) 2010-07-06 2017-12-14 Glaxosmithkline Biologicals Sa Procedimientos de aumento de una respuesta inmunitaria mediante el suministro de ARN
JP6059220B2 (ja) 2011-07-06 2017-01-18 ノバルティス アーゲー 核酸を含む水中油型エマルジョン
US9101669B2 (en) 2012-01-31 2015-08-11 Postech Academy-Industry Foundation Self-assembed conjugate and use thereof
HUE065746T2 (hu) 2012-08-03 2024-06-28 Access To Advanced Health Inst Készítmények és eljárások aktív mycobacterium tuberculosis fertõzés kezelésére
WO2014130761A2 (en) 2013-02-22 2014-08-28 President And Fellows Of Harvard College Nanostructured active therapeutic vehicles and uses thereof
US9775894B2 (en) 2013-07-09 2017-10-03 University Of Washington Through Its Center For Commercialization Methods and compositions for activation of innate immune responses through RIG-I like receptor signaling
RU2546249C2 (ru) 2013-08-07 2015-04-10 Силезиа Груп Пте. Лтд. Композиция для усиления экспрессии трансгена в эукариотических клетках и способ увеличения продукции целевого белка, кодируемого трансгеном
IL310015B2 (en) 2013-12-31 2026-02-01 Access To Advanced Health Inst Single vial formulation
PL4023249T3 (pl) 2014-04-23 2025-03-10 Modernatx, Inc. Szczepionki z kwasem nukleinowym
TWI696700B (zh) 2015-01-16 2020-06-21 國立研究開發法人產業技術總合研究所 使用具有匿跡性之rna的基因表現系統及含有該rna的基因導入、表現載體
CN108064176A (zh) 2015-04-22 2018-05-22 库瑞瓦格股份公司 用于治疗肿瘤疾病的含有rna的组合物
CN106176599A (zh) 2015-05-06 2016-12-07 江苏天士力帝益药业有限公司 一种卡巴他赛脂肪乳注射剂及其制备方法
US11364292B2 (en) 2015-07-21 2022-06-21 Modernatx, Inc. CHIKV RNA vaccines
CN106445676B (zh) * 2015-08-05 2019-10-22 杭州海康威视系统技术有限公司 一种分布式数据计算的任务分配方法和任务分配装置
WO2017053851A1 (en) * 2015-09-23 2017-03-30 Massachusetts Institute Of Technology Compositions and methods for modified dendrimer nanoparticle vaccine delivery
AU2016338672A1 (en) 2015-10-16 2018-04-12 Marinus Pharmaceuticals, Inc. Injectable neurosteroid formulations containing nanoparticles
WO2017070624A1 (en) 2015-10-22 2017-04-27 Modernatx, Inc. Tropical disease vaccines
AU2016341309A1 (en) 2015-10-22 2018-06-07 Modernatx, Inc. Cancer vaccines
JP7384512B2 (ja) 2015-10-22 2023-11-21 モデルナティエックス インコーポレイテッド 広域インフルエンザウイルスワクチン
PL3386484T3 (pl) 2015-12-10 2022-07-25 Modernatx, Inc. Kompozycje i sposoby dostarczania środków terapeutycznych
JP7250520B2 (ja) 2016-04-13 2023-04-03 ヤンセン ファーマシューティカルズ,インコーポレーテッド 組換えアルテリウイルスレプリコン系およびその使用
DE102017206254B4 (de) 2016-04-13 2024-07-11 Dialog Semiconductor (Uk) Limited DC-DC-Umwandlung für Mehrzellen-Batterien
WO2017200957A1 (en) 2016-05-16 2017-11-23 Infectious Disease Research Institute Pegylated liposomes and methods of use
MX2018014086A (es) 2016-05-16 2019-09-18 Infectious Disease Res Inst Formulacion que contiene agonista tlr y metodos de uso.
JP2019521095A (ja) 2016-05-21 2019-07-25 インフェクシャス ディズィーズ リサーチ インスティチュート 二次性結核および非結核性マイコバクテリウム感染症を治療するための組成物および方法
KR20250008135A (ko) 2016-06-01 2025-01-14 액세스 투 어드밴스드 헬스 인스티튜트 사이징제를 함유하는 나노명반 입자
WO2017218704A1 (en) 2016-06-14 2017-12-21 Modernatx, Inc. Stabilized formulations of lipid nanoparticles
WO2018022957A1 (en) * 2016-07-29 2018-02-01 Tarveda Therapeutics, Inc. T cell binding conjugates and methods of use
KR20180025701A (ko) 2016-09-01 2018-03-09 (주)아모레퍼시픽 특정 siRNA을 포함하는 멜라닌 증진용 조성물
BR112019004913B1 (pt) 2016-09-16 2022-07-12 Infectious Disease Research Institute Vacinas que compreendem polipeptídeos de mycobacterium leprae para a prevenção, tratamento e diagnóstico de lepra
KR102718353B1 (ko) 2016-10-17 2024-10-15 얀센 파마슈티칼즈, 인코포레이티드 재조합 바이러스 레플리콘 시스템 및 그의 용도
US20190274968A1 (en) 2016-10-27 2019-09-12 The Trustees Of The University Of Pennsylvania Nucleoside-modified rna for inducing an adaptive immune response
WO2018147710A1 (ko) 2017-02-13 2018-08-16 단디바이오사이언스 주식회사 이미다조퀴놀린계열 물질을 포함하는 나노에멀젼 및 이의 용도
MX2019015076A (es) * 2017-06-15 2020-08-03 Infectious Disease Res Inst Portadores lípidos nanoestructurados y emulsiones estables y usos de los mismos.
US12065649B2 (en) 2018-01-09 2024-08-20 Vanderbilt University Pattern recognition receptor agonist prodrugs and methods of use thereof
JP7494117B2 (ja) 2018-01-19 2024-06-03 ヤンセン ファーマシューティカルズ,インコーポレーテッド 組換えレプリコン系を使用する免疫応答の誘導および増強
WO2019152884A1 (en) 2018-02-02 2019-08-08 University Of Washington Compositions and methods for inducing tripartite motif-containing protein 16 (trim16) signaling
US20190382450A1 (en) 2018-06-18 2019-12-19 University Of Maryland, College Park Newcastle disease virus-based vectored vaccine
US12390812B2 (en) 2018-12-19 2025-08-19 Nuclein, Llc Apparatus and methods for molecular diagnostics
WO2020146690A1 (en) 2019-01-10 2020-07-16 Massachusetts Institute Of Technology Methods for in vitro evolution of rna replicons
US11406699B2 (en) 2019-03-22 2022-08-09 George Mason University Alphavirus and compositions, methods, and kits related thereto
CA3141577A1 (en) 2019-05-25 2020-12-03 Infectious Disease Research Institute Composition and method for spray drying an adjuvant vaccine emulsion
GB201908729D0 (en) 2019-06-18 2019-07-31 Imp College Innovations Ltd RNA construct
US12410241B2 (en) 2019-07-26 2025-09-09 Vanderbilt University Human monoclonal antibodies to enterovirus D68
US11716044B2 (en) * 2019-09-02 2023-08-01 Toshiba Mitsubishi-Electric Industrial Systems Corporation Power conversion device and electric motor drive system
US11679163B2 (en) * 2019-09-20 2023-06-20 Hdt Bio Corp. Compositions and methods for delivery of RNA
WO2021067480A1 (en) 2019-10-02 2021-04-08 University Of Washington Compositions and methods for treatment of hepatitis b virus infection
WO2021072112A1 (en) 2019-10-09 2021-04-15 Hdt Bio Corp. Detection of desmoglein-2 in cancers of epithelial origin
WO2021076630A1 (en) 2019-10-14 2021-04-22 The Regents Of The University Of California Nano-enabled immunotherapy in cancer
KR102754152B1 (ko) * 2019-10-18 2025-01-14 현대모비스 주식회사 사이드 에어백 장치
IL295548A (en) 2020-02-14 2022-10-01 Altimmune Inc Immunogenic compositions of the corona virus and their uses
WO2021178416A1 (en) 2020-03-02 2021-09-10 Heat Biologics, Inc. Immune-mediated coronavirus treatments
WO2021178886A1 (en) 2020-03-06 2021-09-10 Thomas Jefferson University Coronavirus disease (covid-19) vaccine
AU2021236068A1 (en) 2020-03-09 2022-10-06 Arcturus Therapeutics, Inc. Compositions and methods for inducing immune responses
KR20220156933A (ko) * 2020-03-23 2022-11-28 에이치디티 바이오 코포레이션 Rna의 전달을 위한 조성물 및 방법
TWI891771B (zh) 2020-04-17 2025-08-01 美商Vlp醫療股份有限公司 冠狀病毒疫苗
AU2021335334A1 (en) 2020-09-04 2023-04-20 Access To Advanced Health Institute Genetically-adjuvanted rna vaccines
WO2022051022A1 (en) 2020-09-04 2022-03-10 Infectious Disease Research Institute Co-lyophilized rna and nanostructured lipid carrier
EP4048308A1 (en) 2020-12-23 2022-08-31 Infectious Disease Research Institute Solanesol vaccine adjuvants and methods of preparing same
WO2022217079A1 (en) 2021-04-08 2022-10-13 Georgia State University Research Foundation, Inc. Graphene oxide nanoparticles and methods of use for stimulating immune responses
IN202121031414A (https=) 2021-07-13 2023-01-13
IN202121038492A (https=) 2021-08-25 2023-03-03
WO2023056202A2 (en) 2021-09-22 2023-04-06 Hdt Bio Corp. Compositions and methods for enhanced protein production
JP2024535354A (ja) 2021-09-22 2024-09-30 エイチディーティー バイオ コーポレーション がん治療組成物およびその使用
WO2023049363A1 (en) 2021-09-24 2023-03-30 Amgen Inc. Sotorasib and afatinib for treating cancer comprising a kras g12c mutation

Similar Documents

Publication Publication Date Title
JP2023518976A5 (https=)
US11318213B2 (en) Compositions and methods for delivery of RNA
Couvreur et al. Nanotechnology: Intelligent Design to Treat Complex Disease: Couvreur and Vauthier
AU2022349634A1 (en) Nucleic acid sensor agonist compositions and uses thereof
US11679163B2 (en) Compositions and methods for delivery of RNA
WO2023133500A2 (en) Compositions and methods for multivalent immune responses
EP4442257A1 (en) Nanoparticle compositions comprising one or more variants of poly(d,l-lactic-co-glycolic acid)
HK40086331A (zh) 用於rna递送的组合物和方法
Al-Deen On the Delivery of Blood Stage Malaria DNA Vaccine Using Magnetic Nanoparticles
Nawwab Al-Deen On the delivery of blood stage malaria DNA vaccine using magnetic nanoparticles