JP2023516977A5 - - Google Patents
Info
- Publication number
- JP2023516977A5 JP2023516977A5 JP2022552314A JP2022552314A JP2023516977A5 JP 2023516977 A5 JP2023516977 A5 JP 2023516977A5 JP 2022552314 A JP2022552314 A JP 2022552314A JP 2022552314 A JP2022552314 A JP 2022552314A JP 2023516977 A5 JP2023516977 A5 JP 2023516977A5
- Authority
- JP
- Japan
- Prior art keywords
- compound according
- unsubstituted
- substituted
- independently
- group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202062983997P | 2020-03-02 | 2020-03-02 | |
| US62/983,997 | 2020-03-02 | ||
| PCT/US2021/020450 WO2021178396A1 (en) | 2020-03-02 | 2021-03-02 | Imidazole-based synthetic lipidoids for in vivo mrna delivery into immune cells |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023516977A JP2023516977A (ja) | 2023-04-21 |
| JP2023516977A5 true JP2023516977A5 (enExample) | 2024-03-13 |
| JP7716112B2 JP7716112B2 (ja) | 2025-07-31 |
Family
ID=77613658
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022552314A Active JP7716112B2 (ja) | 2020-03-02 | 2021-03-02 | 免疫細胞へのｉｎ ｖｉｖｏでのｍＲＮＡ送達のためのイミダゾール系合成リピドイド |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20230097743A1 (enExample) |
| EP (1) | EP4114467A4 (enExample) |
| JP (1) | JP7716112B2 (enExample) |
| CN (1) | CN115461083A (enExample) |
| CA (1) | CA3170055A1 (enExample) |
| WO (1) | WO2021178396A1 (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20230005367A (ko) * | 2020-05-04 | 2023-01-09 | 트러스티즈 오브 터프츠 칼리지 | 뇌 전달을 위한 합성 지질-유사 물질 |
| US20250268828A1 (en) * | 2021-09-30 | 2025-08-28 | Orna Therapeutics, Inc. | Lipid Nanoparticle Compositions for Delivering Circular Polynucleotides |
| WO2023081526A1 (en) | 2021-11-08 | 2023-05-11 | Orna Therapeutics, Inc. | Lipid nanoparticle compositions for delivering circular polynucleotides |
| CN114805212B (zh) * | 2022-02-22 | 2024-06-18 | 中国科学院基础医学与肿瘤研究所(筹) | 用于递送治疗或预防剂的脂质和脂质组合物 |
| CN119486721A (zh) | 2022-07-08 | 2025-02-18 | 宝利普拉斯生物转染公司 | 包含基于咪唑鎓的阳离子脂质的脂质纳米颗粒 |
| WO2024205657A2 (en) * | 2023-03-29 | 2024-10-03 | Orna Therapeutics, Inc. | Lipids and lipid nanoparticle compositions for delivering polynucleotides |
| WO2025124548A1 (zh) | 2023-12-13 | 2025-06-19 | 上海瑞宏迪医药有限公司 | 一种咪唑类脂质及其应用 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4097475A (en) * | 1974-04-03 | 1978-06-27 | E. I. Du Pont De Nemours And Company | Disperse mono- and bisazo dyes derived from 2-amino-4,5-dicyanoimidazole |
| US20040132788A1 (en) * | 1999-10-11 | 2004-07-08 | Chabrier De Lassauniere Pierre-Etienne | Derivatives of heterocycles with 5 members, their preparation and their use as medicaments |
| WO2006138380A2 (en) * | 2005-06-15 | 2006-12-28 | Massachusetts Institute Of Technology | Amine-containing lipids and uses thereof |
| KR101363278B1 (ko) * | 2005-06-27 | 2014-02-21 | 엑셀리시스 페이턴트 컴퍼니 엘엘씨 | 이미다졸계 ｌｘｒ 변조제 |
| WO2010062322A2 (en) * | 2008-10-27 | 2010-06-03 | Massachusetts Institute Of Technology | Modulation of the immune response |
| US9512073B2 (en) * | 2011-10-27 | 2016-12-06 | Massachusetts Institute Of Technology | Amino acid-, peptide-and polypeptide-lipids, isomers, compositions, and uses thereof |
| IL276322B2 (en) * | 2018-02-01 | 2024-12-01 | Tufts College | Lipid-like nanocomplexes and uses thereof |
-
2021
- 2021-03-02 JP JP2022552314A patent/JP7716112B2/ja active Active
- 2021-03-02 US US17/909,260 patent/US20230097743A1/en active Pending
- 2021-03-02 WO PCT/US2021/020450 patent/WO2021178396A1/en not_active Ceased
- 2021-03-02 EP EP21764086.1A patent/EP4114467A4/en active Pending
- 2021-03-02 CN CN202180032365.0A patent/CN115461083A/zh active Pending
- 2021-03-02 CA CA3170055A patent/CA3170055A1/en active Pending
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