|
US6749853B1
(en)
|
1992-03-05 |
2004-06-15 |
Board Of Regents, The University Of Texas System |
Combined methods and compositions for coagulation and tumor treatment
|
|
GB9324807D0
(en)
|
1993-12-03 |
1994-01-19 |
Cancer Res Campaign Tech |
Tumour antibody
|
|
EP0771216B9
(en)
|
1994-07-11 |
2003-01-02 |
The Board Of Regents, The University Of Texas System |
Methods and compositions for the specific coagulation of tumoral vasculature
|
|
US6117980A
(en)
|
1997-02-21 |
2000-09-12 |
Genentech, Inc. |
Humanized anti-IL-8 monoclonal antibodies
|
|
US20060235209A9
(en)
|
1997-03-10 |
2006-10-19 |
Jin-An Jiao |
Use of anti-tissue factor antibodies for treating thromboses
|
|
US20030109680A1
(en)
|
2001-11-21 |
2003-06-12 |
Sunol Molecular Corporation |
Antibodies for inhibiting blood coagulation and methods of use thereof
|
|
JP2001206899A
(ja)
|
1999-11-18 |
2001-07-31 |
Japan Tobacco Inc |
ＴＧＦ−βＩＩ型受容体に対するヒトモノクローナル抗体及びその医薬用途
|
|
WO2001045636A1
(en)
|
1999-12-20 |
2001-06-28 |
Merck & Co., Inc. |
Pharmaceutical kit
|
|
US8623373B2
(en)
|
2000-02-24 |
2014-01-07 |
Philogen S.P.A. |
Compositions and methods for treatment of angiogenesis in pathological lesions
|
|
WO2001083755A2
(en)
|
2000-04-28 |
2001-11-08 |
La Jolla Institute For Allergy And Immunology |
Human anti-cd40 antibodies and methods of making and using same
|
|
EP1355919B1
(en)
|
2000-12-12 |
2010-11-24 |
MedImmune, LLC |
Molecules with extended half-lives, compositions and uses thereof
|
|
EP1345969B1
(fr)
|
2000-12-26 |
2010-08-11 |
Institut National De La Sante Et De La Recherche Medicale (Inserm) |
Anticorps anti-cd28
|
|
US20040204481A1
(en)
|
2001-04-12 |
2004-10-14 |
Pnina Fishman |
Activation of natural killer cells by adenosine A3 receptor agonists
|
|
CA2456470A1
(en)
|
2001-08-13 |
2003-02-27 |
University Of Southern California |
Interleukin-2 mutants with reduced toxicity
|
|
TWI338009B
(en)
|
2001-10-29 |
2011-03-01 |
Genentech Inc |
Antibodies for inhibiting blood coagulation and methods of use thereof
|
|
WO2003104425A2
(en)
|
2002-06-07 |
2003-12-18 |
The Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services |
Novel stable anti-cd22 antibodies
|
|
US9321832B2
(en)
|
2002-06-28 |
2016-04-26 |
Domantis Limited |
Ligand
|
|
DE60335383D1
(de)
|
2002-07-15 |
2011-01-27 |
Univ Texas |
Antikörper mit bindung an anionische phospholipide und aminophospholipide und ihre verwendung bei der behandlung von virusinfektionen
|
|
JP4463104B2
(ja)
|
2002-08-30 |
2010-05-12 |
財団法人化学及血清療法研究所 |
ヒト抗ヒトインターロイキン−６抗体及び該抗体フラグメント
|
|
ES2559763T3
(es)
|
2002-09-10 |
2016-02-15 |
Affimed Gmbh |
Anticuerpo humano específico de CD3 con propiedades inmunosupresoras
|
|
ES2367430T3
(es)
|
2002-12-23 |
2011-11-03 |
Wyeth Llc |
Anticuerpos contra pd-1 y sus usos.
|
|
US7563869B2
(en)
|
2003-01-23 |
2009-07-21 |
Ono Pharmaceutical Co., Ltd. |
Substance specific to human PD-1
|
|
CA2516832A1
(en)
|
2003-02-27 |
2004-09-10 |
Theravision Gmbh |
A molecule which binds cd80 and cd86
|
|
RU2005132458A
(ru)
|
2003-03-21 |
2006-03-20 |
Уайт (Us) |
Лечение иммунологических расстройств с использованием агонистов интерлейкина-21/рецептора интерлейкина-21
|
|
AU2004244626A1
(en)
|
2003-05-23 |
2004-12-09 |
The Government Of The United States Of America As Represented By The Secretary, Department Of Health And Human Services |
GITR ligand and GITR ligand-related molecules and antibodies and uses thereof
|
|
US9005613B2
(en)
|
2003-06-16 |
2015-04-14 |
Immunomedics, Inc. |
Anti-mucin antibodies for early detection and treatment of pancreatic cancer
|
|
JP2005124568A
(ja)
|
2003-10-01 |
2005-05-19 |
Junichi Masuyama |
細胞活性化方法及びこれを用いる細胞製造方法並びに医薬組成物
|
|
NZ549040A
(en)
|
2004-02-17 |
2009-07-31 |
Schering Corp |
Use for interleukin-33 (IL33) and the IL-33 receptor complex
|
|
US8133485B2
(en)
|
2004-03-30 |
2012-03-13 |
Yissum Research Development Company Of The Hebrew University Of Jerusalem |
Bi-specific complexes for targeting cells involved in allergic-type reactions, compositions and uses thereof
|
|
CA2597098C
(en)
|
2005-02-08 |
2016-08-02 |
Steven R. Ledbetter |
Antibodies to tgfbeta
|
|
US7393833B2
(en)
|
2005-03-09 |
2008-07-01 |
The Board Of Regents Of The University Of Oklahoma |
Chimeric proteins with phosphatidylserine binding domains
|
|
EP1863905B1
(en)
|
2005-03-17 |
2016-01-20 |
UCL Business PLC |
Method for activating natural killer cells by tumour cell preparations in vitro
|
|
CN100509849C
(zh)
|
2005-04-07 |
2009-07-08 |
苏州大学 |
可溶性人cd28分子检测试剂盒及其应用
|
|
US8067546B2
(en)
|
2005-04-19 |
2011-11-29 |
Seattle Genetics, Inc. |
Humanized anti-CD70 binding agents and uses thereof
|
|
EP1877444A2
(en)
|
2005-04-26 |
2008-01-16 |
Pfizer, Inc. |
P-cadherin antibodies
|
|
MX2007013875A
(es)
|
2005-05-11 |
2008-01-28 |
Philogen Spa |
Proteinas de fusion del anticuerpo l19 contra fibronectina ed-b e interlucina 12.
|
|
GB0510790D0
(en)
|
2005-05-26 |
2005-06-29 |
Syngenta Crop Protection Ag |
Anti-CD16 binding molecules
|
|
US7612181B2
(en)
|
2005-08-19 |
2009-11-03 |
Abbott Laboratories |
Dual variable domain immunoglobulin and uses thereof
|
|
EP1777294A1
(en)
|
2005-10-20 |
2007-04-25 |
Institut National De La Sante Et De La Recherche Medicale (Inserm) |
IL-15Ralpha sushi domain as a selective and potent enhancer of IL-15 action through IL-15Rbeta/gamma, and hyperagonist (IL15Ralpha sushi -IL15) fusion proteins
|
|
US8092804B2
(en)
|
2007-12-21 |
2012-01-10 |
Medimmune Limited |
Binding members for interleukin-4 receptor alpha (IL-4Rα)-173
|
|
JP5425180B2
(ja)
|
2008-03-27 |
2014-02-26 |
ザイモジェネティクス， インコーポレイテッド |
ＰＤＧＦＲβおよびＶＥＧＦ−Ａを阻害するための組成物および方法
|
|
KR20180005753A
(ko)
|
2008-06-25 |
2018-01-16 |
에스바테크 - 어 노바티스 컴파니 엘엘씨 |
Ｖｅｇｆ를 억제하는 안정하고 가용성인 항체
|
|
US8822645B2
(en)
|
2008-07-08 |
2014-09-02 |
Abbvie Inc. |
Prostaglandin E2 dual variable domain immunoglobulins and uses thereof
|
|
US9273136B2
(en)
|
2008-08-04 |
2016-03-01 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Fully human anti-human NKG2D monoclonal antibodies
|
|
US8298533B2
(en)
|
2008-11-07 |
2012-10-30 |
Medimmune Limited |
Antibodies to IL-1R1
|
|
MX356367B
(es)
|
2008-12-09 |
2018-05-25 |
Genentech Inc |
Anticuerpos anti-pd-l1 y su uso para mejorar la funcion de celulas t.
|
|
MX2012002651A
(es)
|
2009-09-01 |
2012-05-22 |
Abbott Lab |
Inmunoglobulinas de dominio variable doble y usos de las mismas.
|
|
DE102009045006A1
(de)
|
2009-09-25 |
2011-04-14 |
Technische Universität Dresden |
Anti-CD33 Antikörper und ihre Anwendung zum Immunotargeting bei der Behandlung von CD33-assoziierten Erkrankungen
|
|
AR078651A1
(es)
|
2009-10-15 |
2011-11-23 |
Abbott Lab |
Inmunoglobulinas con dominio variable dual y usos de las mismas
|
|
UY32979A
(es)
|
2009-10-28 |
2011-02-28 |
Abbott Lab |
Inmunoglobulinas con dominio variable dual y usos de las mismas
|
|
NZ601580A
(en)
|
2010-02-11 |
2014-11-28 |
Alexion Pharma Inc |
Therapeutic methods using anti-cd200 antibodies
|
|
EP2560994B1
(en)
|
2010-04-08 |
2016-10-12 |
JN Biosciences LLC |
Antibodies to cd122
|
|
CN103079644B
(zh)
|
2010-06-11 |
2017-02-15 |
协和发酵麒麟株式会社 |
抗tim‑3抗体
|
|
KR20130100118A
(ko)
|
2010-08-03 |
2013-09-09 |
아비에 인코포레이티드 |
이원 가변 도메인 면역글로불린 및 이의 용도
|
|
JP2012034668A
(ja)
|
2010-08-12 |
2012-02-23 |
Tohoku Univ |
ヒト型化抗ｅｇｆｒ抗体リジン置換可変領域断片及びその利用
|
|
JP6251570B2
(ja)
|
2010-09-21 |
2017-12-20 |
アルター・バイオサイエンス・コーポレーション |
多量体ｉｌ−１５可溶性融合分子並びにその製造及び使用方法
|
|
BR112013008738B1
(pt)
|
2010-10-11 |
2017-12-19 |
Abbvie Bahamas Ltd. |
Method for purification of a protein
|
|
CN102153653B
(zh)
|
2010-12-30 |
2012-08-15 |
厦门大学 |
肿瘤血管靶向多肽与组织因子的融合蛋白及其制备方法
|
|
CN102634484A
(zh)
*
|
2011-02-15 |
2012-08-15 |
株式会社赛莱克斯 |
Nk细胞活化方法、使用该方法的nk细胞增殖方法及细胞制备方法以及含nk细胞的单核细胞
|
|
GB201103955D0
(en)
|
2011-03-09 |
2011-04-20 |
Antitope Ltd |
Antibodies
|
|
MX336197B
(es)
|
2011-04-19 |
2016-01-11 |
Merrimack Pharmaceuticals Inc |
Anicuerpos anti-igf-1r y anti-erbb3 monoespecificos y biespecificos.
|
|
EP2703486B1
(en)
|
2011-04-25 |
2018-03-07 |
Daiichi Sankyo Company, Limited |
Anti-b7-h3 antibody
|
|
US9067997B2
(en)
|
2011-05-25 |
2015-06-30 |
Innate Pharma Sa |
Anti-KIR antibodies for the treatment of inflammatory and autoimmune disorders
|
|
US8753640B2
(en)
|
2011-05-31 |
2014-06-17 |
University Of Washington Through Its Center For Commercialization |
MIC-binding antibodies and methods of use thereof
|
|
EP2714735B1
(en)
|
2011-06-03 |
2021-07-21 |
XOMA Technology Ltd. |
Antibodies specific for tgf-beta
|
|
WO2012170470A1
(en)
|
2011-06-06 |
2012-12-13 |
Board Of Regents Of The University Of Nebraska |
Compositions and methods for detection and treatment of cancer
|
|
AU2012273955A1
(en)
|
2011-06-22 |
2014-01-09 |
Inserm (Institut National De La Sante Et De La Recherche Medicale) |
Anti-Axl antibodies and uses thereof
|
|
EP2537933A1
(en)
|
2011-06-24 |
2012-12-26 |
Institut National de la Santé et de la Recherche Médicale (INSERM) |
An IL-15 and IL-15Ralpha sushi domain based immunocytokines
|
|
SG11201401699WA
(en)
|
2011-11-11 |
2014-09-26 |
Rinat Neuroscience Corp |
Antibodies specific for trop-2 and their uses
|
|
CN105861487B
(zh)
|
2012-01-26 |
2020-05-05 |
纽亘技术公司 |
用于靶向核酸序列富集和高效文库产生的组合物和方法
|
|
WO2013134665A1
(en)
|
2012-03-08 |
2013-09-12 |
Selig Sealing Products, Inc. |
Container sealing member with protected security component and removal tab
|
|
KR101535341B1
(ko)
|
2012-07-02 |
2015-07-13 |
한화케미칼 주식회사 |
Dll4에 특이적으로 결합하는 신규한 단일클론항체 및 이의 용도
|
|
US9346872B2
(en)
|
2012-08-08 |
2016-05-24 |
Roche Glycart Ag |
Interleukin-10 fusion proteins
|
|
US20150218280A1
(en)
|
2012-08-10 |
2015-08-06 |
University Of Southern California |
CD20 scFv-ELPs METHODS AND THERAPEUTICS
|
|
US20150259429A1
(en)
|
2012-08-28 |
2015-09-17 |
Institut Curie |
Cluster of differentiation 36 (cd36) as a therapeutic target for hiv infection
|
|
PT3199552T
(pt)
|
2012-11-20 |
2020-03-25 |
Sanofi Sa |
Anticorpos anti-ceacam5 e suas utilizações
|
|
ES2895848T3
(es)
|
2012-12-17 |
2022-02-22 |
Cell Medica Inc |
Anticuerpos contra IL-1 beta
|
|
EP2948475A2
(en)
|
2013-01-23 |
2015-12-02 |
AbbVie Inc. |
Methods and compositions for modulating an immune response
|
|
WO2014130635A1
(en)
|
2013-02-20 |
2014-08-28 |
Novartis Ag |
Effective targeting of primary human leukemia using anti-cd123 chimeric antigen receptor engineered t cells
|
|
US9790274B2
(en)
|
2013-03-14 |
2017-10-17 |
The Board Of Regents Of The University Of Texas System |
Monoclonal antibodies targeting EpCAM for detection of prostate cancer lymph node metastases
|
|
CA2913052A1
(en)
|
2013-05-24 |
2014-11-27 |
Board Of Regents, The University Of Texas System |
Chimeric antigen receptor-targeting monoclonal antibodies
|
|
JP2015030666A
(ja)
|
2013-07-31 |
2015-02-16 |
学校法人順天堂 |
抗ヒトｃｄ２６モノクローナル抗体又はその抗原結合性断片
|
|
CN103709251B
(zh)
|
2013-12-19 |
2016-04-13 |
江苏众红生物工程创药研究院有限公司 |
全人源抗cd26抗体及其应用
|
|
KR102127408B1
(ko)
|
2014-01-29 |
2020-06-29 |
삼성전자주식회사 |
항 Her3 scFv 단편 및 이를 포함하는 항 c-Met/항 Her3 이중 특이 항체
|
|
PL3099717T3
(pl)
|
2014-01-31 |
2019-10-31 |
Novartis Ag |
Cząsteczki przeciwciała dla TIM-3 i ich zastosowanie
|
|
AU2015211674A1
(en)
|
2014-02-03 |
2016-08-04 |
Nanocarrier Co., Ltd. |
Anti-tissue factor monoclonal antibody
|
|
FR3021970B1
(fr)
|
2014-06-06 |
2018-01-26 |
Universite Sciences Technologies Lille |
Anticorps dirige contre la galectine 9 et inhibiteur de l'activite suppressive des lymphocytes t regulateurs
|
|
CA2957722C
(en)
|
2014-08-19 |
2022-05-31 |
Merck Sharp & Dohme Corp. |
Anti-tigit antibodies
|
|
ES2774380T3
(es)
*
|
2014-08-29 |
2020-07-20 |
Hoffmann La Roche |
Politerapia de inmunocitocinas de variante de IL-2 dirigida a tumor y anticuerpos frente a PD-L1 humano
|
|
EP3789039A1
(en)
|
2014-12-22 |
2021-03-10 |
The Rockefeller University |
Anti-mertk agonistic antibodies and uses thereof
|
|
WO2016154585A1
(en)
|
2015-03-26 |
2016-09-29 |
Charles Sentman |
Anti-mica antigen binding fragments, fusion molecules, cells which express and methods of using
|
|
CN108064245A
(zh)
|
2015-04-17 |
2018-05-22 |
埃尔萨里斯生物技术公司 |
抗Tyro3抗体及其用途
|
|
KR101778439B1
(ko)
|
2015-04-27 |
2017-09-14 |
울산대학교 산학협력단 |
자연살해세포 활성화제를 유효성분으로 함유하는 면역증강 및 항암활성증진용 조성물
|
|
EP3307772B1
(en)
|
2015-06-12 |
2020-09-09 |
Ludwig Institute For Cancer Research Limited |
Tgf-beta 3 specific antibodies and methods and uses thereof
|
|
PT3328894T
(pt)
|
2015-08-06 |
2019-02-13 |
Agency Science Tech & Res |
Anticorpos de cadeia comum gama/il2rbeta
|
|
SG11201802915WA
(en)
|
2015-09-11 |
2018-05-30 |
Ys Ac Co Ltd |
Cancer treatment composition combining anti-cd26 antibody and other anticancer agent
|
|
SG10202007764TA
(en)
|
2015-09-25 |
2020-09-29 |
Genentech Inc |
Anti-tigit antibodies and methods of use
|
|
US20190358258A1
(en)
*
|
2015-10-09 |
2019-11-28 |
Robert J. Deans |
Methods for enhancing proliferation of t regulatory cells
|
|
US20190060361A1
(en)
*
|
2015-10-26 |
2019-02-28 |
The Brigham And Women's Hospital, Inc. |
Methods and compositions relating to regulatory t cells
|
|
CN114853907B
(zh)
|
2015-11-13 |
2025-06-27 |
达纳-法伯癌症研究所有限公司 |
用于癌症免疫疗法的nkg2d-ig融合蛋白
|
|
RU2018131123A
(ru)
|
2016-02-17 |
2020-03-17 |
Новартис Аг |
Антитела к tgf-бета2
|
|
RU2756275C2
(ru)
|
2016-03-01 |
2021-09-29 |
Юссум Рисёрч Девелопмент Компани Оф Зэ Хибру Юниверсити Оф Иерусалим Лтд. |
Антитела, специфические к рецептору полиовируса (pvr) человека
|
|
US11963980B2
(en)
|
2016-04-25 |
2024-04-23 |
Musc Foundation For Research Development |
Activated CD26-high immune cells and CD26-negative immune cells and uses thereof
|
|
CN109952369B
(zh)
|
2016-10-05 |
2024-03-22 |
弗罗里达中央大学研究基金会 |
涉及nk细胞和抗pdl1癌症治疗的方法和组合物
|
|
MX2019004681A
(es)
|
2016-10-21 |
2019-10-07 |
Altor Bioscience Corp |
Moleculas basadas en il-15 multimericas.
|
|
JP7790686B2
(ja)
|
2017-01-03 |
2025-12-23 |
バイオアトラ インコーポレイテッド |
老化細胞の処置のためのタンパク質療法
|
|
TW202506185A
(zh)
|
2017-01-20 |
2025-02-16 |
法商賽諾菲公司 |
抗TGF-β抗體及其用途
|
|
AU2018226526B2
(en)
|
2017-02-28 |
2025-03-13 |
Affimed Gmbh |
Combination of an anti-CD16A antibody with a cytokine
|
|
KR102625293B1
(ko)
|
2017-03-06 |
2024-01-15 |
알토 바이오사이언스 엘엘씨 |
Il-12 및 il-18로의 il-15-기반 융합
|
|
CA3058144A1
(en)
|
2017-03-27 |
2018-10-04 |
Nantcell, Inc. |
Ank and il-12 compositions and methods
|
|
EP3421607A1
(en)
|
2017-06-29 |
2019-01-02 |
Fundación Centro Nacional de Investigaciones Oncológicas Carlos III |
Identification and elimination of damaged and/or senescent cells
|
|
JP2020533971A
(ja)
|
2017-08-28 |
2020-11-26 |
アルター・バイオサイエンス・コーポレーション |
Ｉｌ−１５をベースとするｉｌ−７及びｉｌ−２１への融合物
|
|
CN112996805A
(zh)
|
2018-08-30 |
2021-06-18 |
Hcw生物科技公司 |
多链嵌合多肽和其用途
|
|
WO2020047333A1
(en)
|
2018-08-30 |
2020-03-05 |
HCW Biologics, Inc. |
Single-chain chimeric polypeptides and uses thereof
|
|
CA3109139A1
(en)
|
2018-08-30 |
2020-03-05 |
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|
|
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(en)
|
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|
|
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(zh)
|
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|
|
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(en)
|
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|
|
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(en)
|
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|
|
AU2021262794B2
(en)
|
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2026-06-18 |
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|
|
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(en)
|
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2024-07-02 |
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|
|
US12594323B2
(en)
|
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Immunitybio, Inc. |
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|