JP2023511992A5 - - Google Patents

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Publication number
JP2023511992A5
JP2023511992A5 JP2022545423A JP2022545423A JP2023511992A5 JP 2023511992 A5 JP2023511992 A5 JP 2023511992A5 JP 2022545423 A JP2022545423 A JP 2022545423A JP 2022545423 A JP2022545423 A JP 2022545423A JP 2023511992 A5 JP2023511992 A5 JP 2023511992A5
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JP
Japan
Application number
JP2022545423A
Other languages
Japanese (ja)
Other versions
JP2023511992A (ja
JPWO2021152147A5 (https=
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/EP2021/052204 external-priority patent/WO2021152147A1/en
Publication of JP2023511992A publication Critical patent/JP2023511992A/ja
Publication of JP2023511992A5 publication Critical patent/JP2023511992A5/ja
Publication of JPWO2021152147A5 publication Critical patent/JPWO2021152147A5/ja
Priority to JP2025137441A priority Critical patent/JP2025186257A/ja
Pending legal-status Critical Current

Links

JP2022545423A 2020-01-31 2021-01-29 修飾ヌクレオチドを用いた閉じた直鎖dna Pending JP2023511992A (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2025137441A JP2025186257A (ja) 2020-01-31 2025-08-21 修飾ヌクレオチドを用いた閉じた直鎖dna

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP20382063 2020-01-31
EP20382063.4 2020-01-31
PCT/EP2021/052204 WO2021152147A1 (en) 2020-01-31 2021-01-29 Closed linear dna with modified nucleotides

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2025137441A Division JP2025186257A (ja) 2020-01-31 2025-08-21 修飾ヌクレオチドを用いた閉じた直鎖dna

Publications (3)

Publication Number Publication Date
JP2023511992A JP2023511992A (ja) 2023-03-23
JP2023511992A5 true JP2023511992A5 (https=) 2024-02-05
JPWO2021152147A5 JPWO2021152147A5 (https=) 2024-02-05

Family

ID=69713977

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2022545423A Pending JP2023511992A (ja) 2020-01-31 2021-01-29 修飾ヌクレオチドを用いた閉じた直鎖dna
JP2025137441A Pending JP2025186257A (ja) 2020-01-31 2025-08-21 修飾ヌクレオチドを用いた閉じた直鎖dna

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2025137441A Pending JP2025186257A (ja) 2020-01-31 2025-08-21 修飾ヌクレオチドを用いた閉じた直鎖dna

Country Status (8)

Country Link
US (1) US20230323343A1 (https=)
EP (1) EP4097253A1 (https=)
JP (2) JP2023511992A (https=)
KR (1) KR20220133999A (https=)
CN (1) CN115003829A (https=)
AU (1) AU2021213927A1 (https=)
CA (1) CA3164390A1 (https=)
WO (1) WO2021152147A1 (https=)

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EP4083227A1 (en) * 2021-04-29 2022-11-02 4basebio, S.L.U. Linear dna with enhanced resistance against exonucleases
EP4124660A1 (en) * 2021-07-30 2023-02-01 4basebio, S.L.U. Linear dna with enhanced resistance against exonucleases and methods for the production thereof
EP4388118A4 (en) * 2021-08-19 2025-05-21 Twist Bioscience Corporation METHODS AND COMPOSITIONS IN COMPOSITION WITH COVALENTLY CLOSED NUCLEIC ACIDS
CN114075595B (zh) * 2021-11-22 2023-11-17 上海交通大学 甲基化检测组合物、试剂盒及方法
JP2025507359A (ja) * 2022-02-10 2025-03-18 コード バイオセラピューティクス インコーポレイテッド 増強されたdnaデンドリマー及びその使用方法
JP2025516638A (ja) * 2022-05-13 2025-05-30 フラッグシップ パイオニアリング イノベーションズ セブン,エルエルシー 二本鎖dna組成物及び関連する方法
CN115976138A (zh) * 2022-06-02 2023-04-18 宜明(苏州)细胞生物科技有限公司 新型闭合线性双链dna的体外制备技术
WO2024039652A1 (en) 2022-08-16 2024-02-22 Aldevron, L.L.C. Cell-free method of producing synthetic circular nucleic acid
ES3062031T3 (https=) * 2023-02-01 2026-04-08 4Basebio Uk Ltd
EP4410995A1 (en) * 2023-02-01 2024-08-07 4basebio, S.L.U. Linear dna with enhanced resistance against exonucleases and methods for the production thereof
WO2025034978A1 (en) * 2023-08-09 2025-02-13 Code Biotherapeutics, Inc. Enhanced dna dendrimers and methods of use thereof
WO2025064396A1 (en) * 2023-09-18 2025-03-27 Intellia Therapeutics, Inc. Nuclease resistant double stranded dna product for non-viral delivery to a cell and methods of production thereof
WO2025096807A2 (en) * 2023-10-31 2025-05-08 Flagship Pioneering Innovations Vii, Llc Novel therapeutic dna forms
WO2025202929A1 (en) * 2024-03-29 2025-10-02 Pfizer Inc. Methods for producing nucleic acids
EP4663200A1 (en) * 2024-06-10 2025-12-17 CPTx GmbH Compositions and methods
WO2026012450A1 (zh) * 2024-07-11 2026-01-15 石药集团中奇制药技术(石家庄)有限公司 一种非病毒载体介导的大片段dna定点敲入系统

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US4373071A (en) 1981-04-30 1983-02-08 City Of Hope Research Institute Solid-phase synthesis of polynucleotides
JP4517061B2 (ja) * 2003-08-08 2010-08-04 独立行政法人産業技術総合研究所 ダンベル型dnaの効率的な製造方法
CN1918293A (zh) * 2004-02-20 2007-02-21 莫洛根股份公司 用于对人及高等动物进行治疗性和预防性免疫刺激的取代的非编码核酸分子
WO2006085664A1 (ja) 2005-02-10 2006-08-17 The University Of Tokyo ポリカチオン荷電性ポリマー及び核酸のキャリヤーとしての使用
ES2359058B1 (es) 2009-07-02 2012-03-27 Consejo Superior De Investigaciones Cient�?Ficas (Csic) Quimera de adn polimerasa del fago ph1 29.
GB2523187A (en) * 2014-02-18 2015-08-19 Mologen Ag Covalently closed non-coding immunomodulatory DNA construct
US20170067097A1 (en) * 2014-04-11 2017-03-09 Redvault Biosciences, Lp Systems and methods for clonal replication and amplification of nucleic acid molecules for genomic and therapeutic applications
GB201418159D0 (en) * 2014-10-14 2014-11-26 Oxford Nanopore Tech Ltd Method
DK3500682T3 (da) * 2016-08-16 2020-08-24 Touchlight Ip Ltd Fremstilling af lukket, lineært dna
US11473090B2 (en) * 2017-05-16 2022-10-18 Helix Nanotechnologies, Inc. Linear covalently closed vectors and related compositions and methods thereof
EP3714064B8 (en) * 2017-11-21 2024-10-30 4basebio UK Ltd Methods and kits for amplification of double stranded dna

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