JP2023510871A5 - - Google Patents
Info
- Publication number
- JP2023510871A5 JP2023510871A5 JP2022542897A JP2022542897A JP2023510871A5 JP 2023510871 A5 JP2023510871 A5 JP 2023510871A5 JP 2022542897 A JP2022542897 A JP 2022542897A JP 2022542897 A JP2022542897 A JP 2022542897A JP 2023510871 A5 JP2023510871 A5 JP 2023510871A5
- Authority
- JP
- Japan
- Prior art keywords
- wild type
- juvenile
- deleted
- arthritis
- polypeptide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202062960847P | 2020-01-14 | 2020-01-14 | |
| US62/960,847 | 2020-01-14 | ||
| PCT/US2021/013514 WO2021146481A1 (en) | 2020-01-14 | 2021-01-14 | Il2 muteins |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2023510871A JP2023510871A (ja) | 2023-03-15 |
| JP2023510871A5 true JP2023510871A5 (https=) | 2024-01-22 |
Family
ID=76863259
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022542897A Pending JP2023510871A (ja) | 2020-01-14 | 2021-01-14 | Il2ムテイン |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20230210951A1 (https=) |
| EP (1) | EP4090354A4 (https=) |
| JP (1) | JP2023510871A (https=) |
| KR (1) | KR20220127866A (https=) |
| CN (3) | CN115066253A (https=) |
| AU (1) | AU2021207661A1 (https=) |
| CA (1) | CA3166009A1 (https=) |
| IL (1) | IL294070A (https=) |
| MX (1) | MX2022008770A (https=) |
| WO (1) | WO2021146481A1 (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102777151B1 (ko) | 2017-11-21 | 2025-03-05 | 더 보드 어브 트러스티스 어브 더 리랜드 스탠포드 주니어 유니버시티 | 인터루킨-2의 부분 효능제 |
| WO2021146436A2 (en) | 2020-01-14 | 2021-07-22 | Synthekine, Inc. | Biased il2 muteins methods and compositions |
| EP4357357A4 (en) * | 2021-07-30 | 2025-01-08 | Dracoterpin Biomedicine LLC | HUMAN INTERLEUKIN-2 VARIANT AND ITS USE |
| CA3234552A1 (en) | 2021-10-20 | 2023-04-27 | Synthekine, Inc. | Heterodimeric fc cytokines and uses thereof |
| WO2024086739A1 (en) | 2022-10-20 | 2024-04-25 | Synthekine, Inc. | Methods and compositions of il12 muteins and il2 muteins |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DZ2788A1 (fr) * | 1998-05-15 | 2003-12-01 | Bayer Ag | Agonistes et antagonistes selectifs à IL-2. |
| CA2644513A1 (en) * | 2006-03-03 | 2007-09-07 | London Health Sciences Centre Research Inc. | Preventing il-2 mediated inflammation in epithelial cells |
| AU2010206840B2 (en) * | 2009-01-21 | 2015-02-05 | Amgen Inc. | Compositions and methods of treating inflammatory and autoimmune diseases |
| CA2860170C (en) * | 2010-12-22 | 2022-06-14 | The Board Of Trustees Of The Leland Stanford Junior University | Superagonists and antagonists of interleukin-2 |
| WO2015164815A1 (en) * | 2014-04-24 | 2015-10-29 | The Board Of Trustees Of The Leland Stanford Junior University | Superagonists, partial agonists and antagonists of interleukin-2 |
| US9567399B1 (en) * | 2016-06-20 | 2017-02-14 | Kymab Limited | Antibodies and immunocytokines |
| EP3538548A4 (en) * | 2016-11-08 | 2020-08-19 | Delinia, Inc. | IL-2 VARIANTS FOR THE TREATMENT OF AUTOIMMUNE DISEASES |
| EP3707162A1 (en) * | 2017-11-10 | 2020-09-16 | Agency for Science, Technology and Research | Il2rbeta/common gamma chain antibodies |
| KR102777151B1 (ko) * | 2017-11-21 | 2025-03-05 | 더 보드 어브 트러스티스 어브 더 리랜드 스탠포드 주니어 유니버시티 | 인터루킨-2의 부분 효능제 |
| KR20250156190A (ko) * | 2018-06-22 | 2025-10-31 | 큐진 인크. | 인터루킨-2 변이체 및 이의 사용 방법 |
-
2021
- 2021-01-14 CA CA3166009A patent/CA3166009A1/en active Pending
- 2021-01-14 CN CN202180009469.XA patent/CN115066253A/zh active Pending
- 2021-01-14 MX MX2022008770A patent/MX2022008770A/es unknown
- 2021-01-14 US US17/785,786 patent/US20230210951A1/en active Pending
- 2021-01-14 JP JP2022542897A patent/JP2023510871A/ja active Pending
- 2021-01-14 CN CN202511566821.6A patent/CN121554597A/zh active Pending
- 2021-01-14 EP EP21741554.6A patent/EP4090354A4/en active Pending
- 2021-01-14 AU AU2021207661A patent/AU2021207661A1/en active Pending
- 2021-01-14 IL IL294070A patent/IL294070A/en unknown
- 2021-01-14 WO PCT/US2021/013514 patent/WO2021146481A1/en not_active Ceased
- 2021-01-14 KR KR1020227027688A patent/KR20220127866A/ko active Pending
- 2021-01-14 CN CN202511566818.4A patent/CN121319219A/zh active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2023510871A5 (https=) | ||
| RU2464276C2 (ru) | Улучшенные нанотела против фактора некроза опухоли-альфа | |
| JP2006516094A5 (https=) | ||
| Clements et al. | The crystal structure of myelin oligodendrocyte glycoprotein, a key autoantigen in multiple sclerosis | |
| JP2019523653A5 (https=) | ||
| JP3328644B2 (ja) | 病原性ボレリア・ブルグドルフェリ菌株、病原性ボレリア・ブルグドルフェリの単離及び再培養法 | |
| ES2402650T3 (es) | Métodos de purificación de anticuerpos anti A beta | |
| US8357778B2 (en) | Polypeptide, an affinity chromatography material, and a method for separating and/or purifying immunoglobulin | |
| JP2022020674A5 (https=) | ||
| RU2006127314A (ru) | Вакцина, стимулирующая рост, основанная на нейтрализующем эпитопе | |
| IL276286B2 (en) | FC variants with improved binding to FCRN and extended half-life | |
| JP2006510619A5 (https=) | ||
| DK2000535T3 (da) | Sekvenser af circovirus type B forbundet med udmagringssygdom hos pattegrise (PWD). | |
| HRP20150937T1 (hr) | Pentaspecifiäśno protutijelo | |
| US20250266122A1 (en) | Multi-domain proteins with increased native state colloidal stability | |
| CN113840835A (zh) | 结合分子 | |
| RU2223115C2 (ru) | ГУМАНИЗИРОВАННАЯ АНТИ-Fas АНТИТЕЛОПОДОБНАЯ МОЛЕКУЛА (ВАРИАНТЫ), ДНК (ВАРИАНТЫ), ВЕКТОР (ВАРИАНТЫ), ПОЛИПЕПТИД, СПОСОБ ПОЛУЧЕНИЯ, ИСПОЛЬЗОВАНИЕ АНТИТЕЛА | |
| RU99120702A (ru) | Гуманизированная анти-Fas антитело-подобная молекула (варианты), ДНК (варианты), вектор (варианты), полипептид, способ получения, использование антитела | |
| JP2002544237A5 (https=) | ||
| JP2006521082A5 (https=) | ||
| Yamanaka et al. | Cloning and sequence analysis of the hemagglutinin gene of the virulent strain of rinderpest virus | |
| JP2024023268A5 (https=) | ||
| Luo et al. | Prediction of three-dimensional models for foot-and-mouth disease virus and hepatitis A virus | |
| US10995133B2 (en) | Method for producing antibody | |
| JP2023542737A5 (https=) |